Bipolaris or Curvularia? Resolving the spicy issue of how clinical isolates should be reported

Sarah E. Kidd, Lars F. Westblade

PLOS Pathogens: published November 20, 2024 | https://doi.org/10.1371/journal.ppat.1012678

TMPRSS2 in microbial interactions: Insights from HKU1 and TcsH

Zhengyang Pan, Daoqun Li, Leiliang Zhang

PLOS Pathogens: published November 20, 2024 | https://doi.org/10.1371/journal.ppat.1012677

Adaptation of Candida albicans to specific host environments by gain-of-function mutations in transcription factors

Joachim Morschhäuser

PLOS Pathogens: published November 4, 2024 | https://doi.org/10.1371/journal.ppat.1012643

Eimeria: Navigating complex intestinal ecosystems

Shengjie Weng, Erjie Tian, Meng Gao, Siyu Zhang, Guodong Yang, Bianhua Zhou

PLOS Pathogens: published November 22, 2024 | https://doi.org/10.1371/journal.ppat.1012689

CD4⁺ but not CD8⁺ T cells are required for protection against severe guinea pig cytomegalovirus infections

Tyler B. Rollman, Zachary W. Berkebile, Dustin M. Hicks, Jason S. Hatfield, Priyanka Chauhan, Marco Pravetoni, Mark R. Schleiss, Gregg N. Milligan, Terry K. Morgan, Craig J. Bierle

PLOS Pathogens: published November 4, 2024 | https://doi.org/10.1371/journal.ppat.1012515

Copper acquisition is essential for plant colonization and virulence in a root-infecting vascular wilt fungus

Rafael Palos-Fernández, María Victoria Aguilar-Pontes, Gema Puebla-Planas, Harald Berger, Lena Studt-Reinhold, Joseph Strauss, Antonio Di Pietro, Manuel Sánchez López-Berges

PLOS Pathogens: published November 4, 2024 | https://doi.org/10.1371/journal.ppat.1012671

Tissue specific innate immune responses impact viral infection in Drosophila

Elisha Segrist, Steven Miller, Beth Gold, Yue Li, Sara Cherry

PLOS Pathogens: published November 4, 2024 | https://doi.org/10.1371/journal.ppat.1012672

Suppressing neutrophil itaconate production attenuates Mycoplasma pneumoniae pneumonia

Cui Wang, Jun Wen, Zijun Yan, Yujun Zhou, Zhande Gong, Ying Luo, Zhenkui Li, Kang Zheng, Haijun Zhang, Nan Ding, Chuan Wang, Cuiming Zhu, Yimou Wu, Aihua Lei

PLOS Pathogens: published November 5, 2024 | https://doi.org/10.1371/journal.ppat.1012614

A major role of class III HD-ZIPs in promoting sugar beet cyst nematode parasitism in Arabidopsis

Xunliang Liu, Melissa G. Mitchum

PLOS Pathogens: published November 7, 2024 | https://doi.org/10.1371/journal.ppat.1012610

Metarhizium fight club: Within-host competitive exclusion and resource partitioning

Huiyu Sheng, Raymond J. St. Leger

PLOS Pathogens: published November 7, 2024 | https://doi.org/10.1371/journal.ppat.1012639

Reduction of antisense transcription affects bovine leukemia virus replication and oncogenesis

Thomas Joris, Thomas Jouant, Jean-Rock Jacques, Lorian Gouverneur, Xavier Saintmard, Lea Vilanova Mañá, Majeed Jamakhani, Michal Reichert, Luc Willems

PLOS Pathogens: published November 7, 2024 | https://doi.org/10.1371/journal.ppat.1012659

A viral p3a protein targets and inhibits TaDOF transcription factors to promote the expression of susceptibility genes and facilitate viral infection

Shuyuan Tian, Qingting Song, Yipeng Cheng, Wenmei Zhou, Kuan Wu, Yu Zhao, Yunfeng Wu, Lei Zhao

PLOS Pathogens: published November 7, 2024 | https://doi.org/10.1371/journal.ppat.1012680

Use of the Puccinia sorghi haustorial transcriptome to identify and characterize AvrRp1-D recognized by the maize Rp1-D resistance protein

Saet-Byul Kim, Ki-Tae Kim, Solhee In, Namrata Jaiswal, Gir-Won Lee, Seungmee Jung, Abigail Rogers, Libia F. Gómez-Trejo, Sujan Gautam, Matthew Helm, Hee-Kyung Ahn, Hye-Young Lee, Quentin D. Read, Jongchan Woo, Katerina L. Holan, Steven A. Whitham, Jonathan D. G. Jones, Doil Choi, Ralph Dean, Eunsook Park, Peter Balint-Kurti

PLOS Pathogens: published November 8, 2024 | https://doi.org/10.1371/journal.ppat.1012662

Structural basis for human DPP4 receptor recognition by a pangolin MERS-like coronavirus

Mo Yang, Zehou Li, Jing Chen, Yang Li, Ran Xu, Meihua Wang, Ying Xu, Rong Chen, Weiwei Ji, Xiaoxia Li, Jiayu Wei, Zhengrong Zhou, Minjie Ren, Ke Ma, Jiayu Guan, Guoxiang Mo, Peng Zhou, Bo Shu, Jingjing Guo, Yuan Yuan, Zheng-Li Shi, Shuijun Zhang

PLOS Pathogens: published November 8, 2024 | https://doi.org/10.1371/journal.ppat.1012695

TRIM32 inhibits Venezuelan equine encephalitis virus infection by targeting a late step in viral entry

Yifan Xie, Jie Cao, Shuyi Gan, Lingdong Xu, Dongjie Zhang, Suhong Qian, Feng Xu, Qiang Ding, John W. Schoggins, Wenchun Fan

PLOS Pathogens: published November 11, 2024 | https://doi.org/10.1371/journal.ppat.1012312

A model of lymphocryptovirus-associated post-transplant lymphoproliferative disorder in immunosuppressed Mauritian cynomolgus macaques

Helen L. Wu, Whitney C. Weber, Courtney M. Waytashek, Carla D. Boyle, Jason S. Reed, Katherine B. Bateman, Hannah K. Fisher, Yan Chen, Kimberly Armantrout, Tonya Swanson, Christine Shriver-Munsch, Mina Northrup, Miranda Fischer, Sreya Biswas, John Templon, Angela Panoskaltsis-Mortari, Benjamin J. Burwitz, Amanda L. Johnson, Lois Colgin, Anne D. Lewis, Jeremy V. Smedley, Michael K. Axthelm, Rebecca Skalsky, Gabrielle Meyers, Richard T. Maziarz, Erik Mittra, Melissa Berg, Jeffrey J. Stanton, Jonah B. Sacha

PLOS Pathogens: published November 11, 2024 | https://doi.org/10.1371/journal.ppat.1012644

Super broad and protective nanobodies against Sarbecoviruses including SARS-CoV-1 and the divergent SARS-CoV-2 subvariant KP.3.1.1

Haodi Dong, Runhong Zhou, Jing Chen, Jing Wei, Zimeng Wei, Ziqing Yang, Kun Zhu, Yufan Yang, Qianqian Yang, Na Liu, Yuting Chen, Yuhan Wu, Yan Liang, Yige Zeng, Qile Guo, Mingxi Li, Sisi Shan, Han Wang, Mengyue Niu, Isabella Yunfei Zeng, Xuanling Shi, Qi Zhang, Xinquan Wang, Zhiwei Chen, Linqi Zhang

PLOS Pathogens: published November 11, 2024 | https://doi.org/10.1371/journal.ppat.1012625

The Plasmodium transmission-blocking symbiont, Microsporidia MB, is vertically transmitted through Anopheles arabiensis germline stem cells

Thomas Ogao Onchuru, Edward Edmond Makhulu, Purity Cassandra Ronnie, Stancy Mandere, Fidel Gabriel Otieno, Joseph Gichuhi, Jeremy Keith Herren

PLOS Pathogens: published November 11, 2024 | https://doi.org/10.1371/journal.ppat.1012340

Critical role of Babesia bovis spherical body protein 3 in ridge formation on infected red blood cells

Atefeh Fathi, Hassan Hakimi, Miako Sakaguchi, Junya Yamagishi, Shin-ichiro Kawazu, Masahito Asada

PLOS Pathogens: published November 11, 2024 | https://doi.org/10.1371/journal.ppat.1012294

Anchorage of bacterial effector at plasma membrane via selective phosphatidic acid binding to modulate host cell signaling

Meng Wang, Qixiao Guan, Chunyan Wang, Lyubin Hu, Xueyan Hu, Menglin Xu, Yuhao Cai, Haoran Zhang, Qing Cao, Huiming Sheng, Xiaohui Wei, Jane E. Koehler, Hongjing Dou, Ruo-xu Gu, Congli Yuan

PLOS Pathogens: published November 12, 2024 | https://doi.org/10.1371/journal.ppat.1012694

Mycoplasma bovis 5′-nucleotidase is a virulence factor conferring mammary fitness in bovine mastitis

Aga E. Gelgie, Peleg Schneider, Christine Citti, Emilie Dordet-Frisoni, Barbara E. Gillespie, Raúl A. Almeida, Getahun E. Agga, Yaa Serwaah Amoah, Nahum Y. Shpigel, Oudessa Kerro Dego, Inna Lysnyansky

PLOS Pathogens: published November 12, 2024 | https://doi.org/10.1371/journal.ppat.1012628

ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization

Lu Zhang, Hsiu-Hsin Cheng, Nadine Krüger, Bojan Hörnich, Luise Graichen, Alexander S. Hahn, Sebastian R. Schulz, Hans-Martin Jäck, Metodi V. Stankov, Georg M. N. Behrens, Marcel A. Müller, Christian Drosten, Onnen Mörer, Martin Sebastian Winkler, ZhaoHui Qian, Stefan Pöhlmann, Markus Hoffmann

PLOS Pathogens: published November 13, 2024 | https://doi.org/10.1371/journal.ppat.1012653

Single-cell transcriptomics unveils skin cell specific antifungal immune responses and IL-1Ra- IL-1R immune evasion strategies of emerging fungal pathogen Candida auris

Abishek Balakumar, Diprasom Das, Abhishek Datta, Abtar Mishra, Garrett Bryak, Shrihari M. Ganesh, Mihai G. Netea, Vinod Kumar, Michail S. Lionakis, Devender Arora, Jyothi Thimmapuram, Shankar Thangamani

PLOS Pathogens: published November 13, 2024 | https://doi.org/10.1371/journal.ppat.1012699

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite Entamoeba histolytica

Misato Shimoyama, Kumiko Nakada-Tsukui, Tomoyoshi Nozaki

PLOS Pathogens: published November 13, 2024 | https://doi.org/10.1371/journal.ppat.1012364

Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design

Rebekah A. Jones, Fidel Ramirez-Bencomo, Gail Whiting, Min Fang, Hayley Lavender, Kacper Kurzyp, Angela Thistlethwaite, Lenka Stejskal, Smruti Rashmi, Ann E. Jerse, Ana Cehovin, Jeremy P. Derrick, Christoph M. Tang

PLOS Pathogens: published November 14, 2024 | https://doi.org/10.1371/journal.ppat.1012688

NS1-mediated DNMT1 degradation regulates human bocavirus 1 replication and RNA processing

Shuangkang Qin, Honghe Chen, Chuchu Tian, Zhen Chen, Li Zuo, Xueyan Zhang, Haojie Hao, Fang Huang, Haibin Liu, Xiulian Sun, Wuxiang Guan

PLOS Pathogens: published November 14, 2024 | https://doi.org/10.1371/journal.ppat.1012682

Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses

Ravi Ojha, Anmin Jiang, Elina Mäntylä, Tania Quirin, Naphak Modhira, Robert Witte, Arnaud Gaudin, Lisa De Zanetti, Rachel Sarah Gormal, Maija Vihinen-Ranta, Jason Mercer, Maarit Suomalainen, Urs F. Greber, Yohei Yamauchi, Pierre-Yves Lozach, Ari Helenius, Olli Vapalahti, Paul Young, Daniel Watterson, Frédéric A. Meunier, Merja Joensuu, Giuseppe Balistreri

PLOS Pathogens: published November 14, 2024 | https://doi.org/10.1371/journal.ppat.1012690

Distinct pathways for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses

Alexandra L. Tse, Cory M. Acreman, Inna Ricardo-Lax, Jacob Berrigan, Gorka Lasso, Toheeb Balogun, Fiona L. Kearns, Lorenzo Casalino, Georgia L. McClain, Amartya Mudry Chandran, Charlotte Lemeunier, Rommie E. Amaro, Charles M. Rice, Rohit K. Jangra, Jason S. McLellan, Kartik Chandran, Emily Happy Miller

PLOS Pathogens: published November 15, 2024 | https://doi.org/10.1371/journal.ppat.1012704

The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors

Silke Malmsheimer, Iwan Grin, Erwin Bohn, Mirita Franz-Wachtel, Boris Macek, Tobias Sahr, Fabian Smollich, David Chetrit, Amit Meir, Craig Roy, Carmen Buchrieser, Samuel Wagner

PLOS Pathogens: published November 15, 2024 | https://doi.org/10.1371/journal.ppat.1012118

Mucosal immunization with the lung Lactobacillus-derived amphiphilic exopolysaccharide adjuvanted recombinant vaccine improved protection against P. aeruginosa infection

Haochi Zhang, Shouxin Sheng, Chunhe Li, Xuemei Bao, Lixia Zhao, Jian Chen, Pingyuan Guan, Xiaoyan Li, Na Pan, Yanchen Liang, Xueqi Wang, Jingmin Sun, Xiao Wang

PLOS Pathogens: published November 18, 2024 | https://doi.org/10.1371/journal.ppat.1012696

Attenuated Getah virus confers protection against multiple arthritogenic alphaviruses

Zhiwen Jiang, Andres Merits, Ying Qin, Gang Xing, Letian Zhang, Jie Chen, Ningning Wang, Margus Varjak, Xiaofeng Zhai, Dongyan Li, Wanjie Song, Shuo Su

PLOS Pathogens: published November 18, 2024 | https://doi.org/10.1371/journal.ppat.1012700

The blast pathogen effector AVR-Pik binds and stabilizes rice heavy metal-associated (HMA) proteins to co-opt their function in immunity

Kaori Oikawa, Koki Fujisaki, Motoki Shimizu, Takumi Takeda, Keiichiro Nemoto, Hiromasa Saitoh, Akiko Hirabuchi, Yukie Hiraka, Naomi Miyaji, Aleksandra Białas, Thorsten Langner, Ronny Kellner, Tolga O Bozkurt, Stella Cesari, Thomas Kroj, Mark J Banfield, Sophien Kamoun, Ryohei Terauchi

PLOS Pathogens: published November 18, 2024 | https://doi.org/10.1371/journal.ppat.1012647

Polyamines mediate cellular energetics and lipid metabolism through mitochondrial respiration to facilitate virus replication

Yazmin E. Cruz-Pulido, Natalie J. LoMascolo, Delaina May, Jomana Hatahet, Caroline E. Thomas, Andrea K. W. Chu, Samantha P. Stacey, Maria del Mar Villanueva Guzman, Gregory Aubert, Bryan C. Mounce

PLOS Pathogens: published November 18, 2024 | https://doi.org/10.1371/journal.ppat.1012711

Profiling serum immunodominance following SARS-CoV-2 primary and breakthrough infection reveals distinct variant-specific epitope usage and immune imprinting

Jeffrey Seow, George C. E. Jefferson, Michael D. Keegan, Yeuk Yau, Luke B. Snell, Katie J. Doores

PLOS Pathogens: published November 18, 2024 | https://doi.org/10.1371/journal.ppat.1012724

AGC family kinase of Entamoeba histolytica: Decoding the members biochemically

Azhar Ahmad, Vikas Kumar, Tushar Kushwaha, Akash Kumar, Deepak Sehgal, Krishna K. Inampudi, Somlata

PLOS Pathogens: published November 19, 2024 | https://doi.org/10.1371/journal.ppat.1012729

Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection

Mathias Franzén Boger, Tyra Hasselrot, Vilde Kaldhusdal, Gisele H. B. Miranda, Paulo Czarnewski, Gabriella Edfeldt, Frideborg Bradley, Genta Rexaj, Julie Lajoie, Kenneth Omollo, Joshua Kimani, Keith R. Fowke, Kristina Broliden, Annelie Tjernlund

PLOS Pathogens: published November 19, 2024 | https://doi.org/10.1371/journal.ppat.1012709

Antagonism of BST2/Tetherin, a new restriction factor of respiratory syncytial virus, requires the viral NS1 protein

Katherine Marougka, Delphine Judith, Tristan Jaouen, Sabine Blouquit-Laye, Gina Cosentino, Clarisse Berlioz-Torrent, Marie-Anne Rameix-Welti, Delphine Sitterlin

PLOS Pathogens: published November 19, 2024 | https://doi.org/10.1371/journal.ppat.1012687

The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence

Patricia P. Peterson, Jin-Tae Choi, Ci Fu, Leah E. Cowen, Sheng Sun, Yong-Sun Bahn, Joseph Heitman

PLOS Pathogens: published November 19, 2024 | https://doi.org/10.1371/journal.ppat.1012735

Enterovirus A71 and coxsackievirus A6 circulation in England, UK, 2006–2017: A mathematical modelling study using cross-sectional seroprevalence data

Everlyn Kamau, Ben Lambert, David J. Allen, Cristina Celma, Stuart Beard, Heli Harvala, Peter Simmonds, Nicholas C. Grassly, Margarita Pons-Salort

PLOS Pathogens: published November 20, 2024 | https://doi.org/10.1371/journal.ppat.1012703

Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin

Fabiana Bisaro, Clay D. Jackson-Litteken, Jenna C. McGuffey, Anna J. Hooppaw, Sophie Bodrog, Leila Jebeli, Manon Janet-Maitre, Juan C. Ortiz-Marquez, Tim van Opijnen, Nichollas E. Scott, Gisela Di Venanzio, Mario F. Feldman

PLOS Pathogens: published November 21, 2024 | https://doi.org/10.1371/journal.ppat.1012705

Massive entry of BK Polyomavirus induces transient cytoplasmic vacuolization of human renal proximal tubule epithelial cells

Elias Myrvoll Lorentzen, Stian Henriksen, Christine Hanssen Rinaldo

PLOS Pathogens: published November 21, 2024 | https://doi.org/10.1371/journal.ppat.1012681

SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation

Abdullah M. Syed, Alison Ciling, Irene P. Chen, Christopher R. Carlson, Armin N. Adly, Hannah S. Martin, Taha Y. Taha, Mir M. Khalid, Nathan Price, Mehdi Bouhaddou, Manisha R. Ummadi, Jack M. Moen, Nevan J. Krogan, David O. Morgan, Melanie Ott, Jennifer A. Doudna

PLOS Pathogens: published November 21, 2024 | https://doi.org/10.1371/journal.ppat.1012741

Membrane fluidity control by the Magnaporthe oryzae acyl-CoA binding protein sets the thermal range for host rice cell colonization

Michael Richter, Lauren M. Segal, Raquel O. Rocha, Nisha Rokaya, Aline R. de Queiroz, Wayne R. Riekhof, Rebecca L. Roston, Richard A. Wilson

PLOS Pathogens: published November 25, 2024 | https://doi.org/10.1371/journal.ppat.1012738

N6-methyladenosine RNA modification promotes Severe Fever with Thrombocytopenia Syndrome Virus infection

Zhiqiang Chen, Jinyu Zhang, Jun Wang, Hao Tong, Wen Pan, Feng Ma, Qihan Wu, Jianfeng Dai

PLOS Pathogens: published November 25, 2024 | https://doi.org/10.1371/journal.ppat.1012725

Examining the molecular clock hypothesis for the contemporary evolution of the rabies virus

Rowan Durrant, Christina A. Cobbold, Kirstyn Brunker, Kathryn Campbell, Jonathan Dushoff, Elaine A. Ferguson, Gurdeep Jaswant, Ahmed Lugelo, Kennedy Lushasi, Lwitiko Sikana, Katie Hampson

PLOS Pathogens: published November 25, 2024 | https://doi.org/10.1371/journal.ppat.1012740

Seoul orthohantavirus evades innate immune activation by reservoir endothelial cells

Stefan D. Klimaj, Autumn LaPointe, Kimberly Martinez, Eduardo Hernandez Acosta, Alison M. Kell

PLOS Pathogens: published November 25, 2024 | https://doi.org/10.1371/journal.ppat.1012728

Trim72 is a major host factor protecting against lethal Candida albicans infection

Wang Tan, Jiayu Liu, Renlin Yu, Ping Zhao, Yuhan Liu, Qian Lu, Ke Wang, Hao Ding, Yi Liu, Xiaofei Lai, Ju Cao

PLOS Pathogens: published November 25, 2024 | https://doi.org/10.1371/journal.ppat.1012747

Viral genomic methylation and the interspecies evolutionary relationships of ranavirus

Weiqiang Pan, Mincong Liang, Yanlin You, Zhimin Li, Shaoping Weng, Jianguo He, Changjun Guo

PLOS Pathogens: published November 25, 2024 | https://doi.org/10.1371/journal.ppat.1012736

Discovery of Nanosota-9 as anti-Omicron nanobody therapeutic candidate

Gang Ye, Fan Bu, Divyasha Saxena, Hailey Turner-Hubbard, Morgan Herbst, Benjamin Spiller, Brian E. Wadzinski, Lanying Du, Bin Liu, Jian Zheng, Fang Li

PLOS Pathogens: published November 26, 2024 | https://doi.org/10.1371/journal.ppat.1012726

Coronavirus nucleocapsid protein enhances the binding of p-PKCα to RACK1: Implications for inhibition of nucleocytoplasmic trafficking and suppression of the innate immune response

Wenxiang Xue, Hongyan Chu, Jiehuang Wang, Yingjie Sun, Xusheng Qiu, Cuiping Song, Lei Tan, Chan Ding, Ying Liao

PLOS Pathogens: published November 27, 2024 | https://doi.org/10.1371/journal.ppat.1012097

Human norovirus disturbs intestinal motility and transit time through its capsid proteins

Arno Cuvry, Lorane Molineaux, Roberto Gozalbo-Rovira, Johan Neyts, Peter de Witte, Jesús Rodríguez-Díaz, Joana Rocha-Pereira

PLOS Pathogens: published November 27, 2024 | https://doi.org/10.1371/journal.ppat.1012710

Retraction: p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication

The PLOS Pathogens Editors

PLOS Pathogens: published November 8, 2024 | https://doi.org/10.1371/journal.ppat.1012698

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