Is antimicrobial resistance evolution accelerating?

Christopher Witzany, Sebastian Bonhoeffer, Jens Rolff

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008905

Rapid deployment of SARS-CoV-2 testing: The CLIAHUB

Emily D. Crawford, Irene Acosta, Vida Ahyong, Erika C. Anderson, Shaun Arevalo, Daniel Asarnow, Shannon Axelrod, Patrick Ayscue, Camillia S. Azimi, Caleigh M. Azumaya, Stefanie Bachl, Iris Bachmutsky, Aparna Bhaduri, Jeremy Bancroft Brown, Joshua Batson, Astrid Behnert, Ryan M. Boileau, Saumya R. Bollam, Alain R. Bonny, David Booth, Michael Jerico B. Borja, David Brown, Bryan Buie, Cassandra E. Burnett, Lauren E. Byrnes, Katelyn A. Cabral, Joana P. Cabrera, Saharai Caldera, Gabriela Canales, Gloria R. Castañeda, Agnes Protacio Chan, Christopher R. Chang, Arthur Charles-Orszag, Carly Cheung, Unseng Chio, Eric D. Chow, Y. Rose Citron, Allison Cohen, Lillian B. Cohn, Charles Chiu, Mitchel A. Cole, Daniel N. Conrad, Angela Constantino, Andrew Cote, Tre’Jon Crayton-Hall, Spyros Darmanis, Angela M. Detweiler, Rebekah L. Dial, Shen Dong, Elias M. Duarte, David Dynerman, Rebecca Egger, Alison Fanton, Stacey M. Frumm, Becky Xu Hua Fu, Valentina E. Garcia, Julie Garcia, Christina Gladkova, Miriam Goldman, Rafael Gomez-Sjoberg, M. Grace Gordon, James C. R. Grove, Shweta Gupta, Alexis Haddjeri-Hopkins, Pierce Hadley, John Haliburton, Samantha L. Hao, George Hartoularos, Nadia Herrera, Melissa Hilberg, Kit Ying E. Ho, Nicholas Hoppe, Shayan Hosseinzadeh, Conor J. Howard, Jeffrey A. Hussmann, Elizabeth Hwang, Danielle Ingebrigtsen, Julia R. Jackson, Ziad M. Jowhar, Danielle Kain, James Y. S. Kim, Amy Kistler, Oriana Kreutzfeld, Jessie Kulsuptrakul, Andrew F. Kung, Charles Langelier, Matthew T. Laurie, Lena Lee, Kun Leng, Kristoffer E. Leon, Manuel D. Leonetti, Sophia R. Levan, Sam Li, Aileen W. Li, Jamin Liu, Heidi S. Lubin, Amy Lyden, Jennifer Mann, Sabrina Mann, Gorica Margulis, Diana M. Marquez, Bryan P. Marsh, Calla Martyn, Elizabeth E. McCarthy, Aaron McGeever, Alexander F. Merriman, Lauren K. Meyer, Steve Miller, Megan K. Moore, Cody T. Mowery, Tanzila Mukhtar, Lusajo L. Mwakibete, Noelle Narez, Norma F. Neff, Lindsay A. Osso, Diter Oviedo, Suping Peng, Maira Phelps, Kiet Phong, Peter Picard, Lindsey M. Pieper, Neha Pincha, Angela Oliveira Pisco, Angela Pogson, Sergei Pourmal, Robert R. Puccinelli, Andreas S. Puschnik, Elze Rackaityte, Preethi Raghavan, Madhura Raghavan, James Reese, Joseph M. Replogle, Hanna Retallack, Helen Reyes, Donald Rose, Marci F. Rosenberg, Estella Sanchez-Guerrero, Sydney M. Sattler, Laura Savy, Stephanie K. See, Kristin K. Sellers, Paula Hayakawa Serpa, Maureen Sheehy, Jonathan Sheu, Sukrit Silas, Jessica A. Streithorst, Jack Strickland, Doug Stryke, Sara Sunshine, Peter Suslow, Renaldo Sutanto, Serena Tamura, Michelle Tan, Jiongyi Tan, Alice Tang, Cristina M. Tato, Jack C. Taylor, Iliana Tenvooren, Erin M. Thompson, Edward C. Thornborrow, Eric Tse, Tony Tung, Marc L. Turner, Victoria S. Turner, Rigney E. Turnham, Mary J. Turocy, Trisha V. Vaidyanathan, Ilia D. Vainchtein, Manu Vanaerschot, Sara E. Vazquez, Anica M. Wandler, Anne Wapniarski, James T. Webber, Zara Y. Weinberg, Alexandra Westbrook, Allison W. Wong, Emily Wong, Gajus Worthington, Fang Xie, Albert Xu, Terrina Yamamoto, Ying Yang, Fauna Yarza, Yefim Zaltsman, Tina Zheng, Joseph L. DeRisi

PLOS Pathogens: published October 28, 2020 | https://doi.org/10.1371/journal.ppat.1008966

“Trained immunity” from Mycobacterium spp. exposure or BCG vaccination and COVID-19 outcomes

Samer Singh, Rajendra Prakash Maurya, Rakesh K. Singh

PLOS Pathogens: published October 29, 2020 | https://doi.org/10.1371/journal.ppat.1008969

Immunometabolism in Caenorhabditis elegans

Sarah M. Anderson, Read Pukkila-Worley

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008897

Antimicrobial surfaces: A need for stewardship?

Sam S. Cassidy, David J. Sanders, Jim Wade, Ivan P. Parkin, Claire J. Carmalt, Andrew M. Smith, Elaine Allan

PLOS Pathogens: published October 15, 2020 | https://doi.org/10.1371/journal.ppat.1008880

Antibiotic tolerance

Lars F. Westblade, Jeff Errington, Tobias Dörr

PLOS Pathogens: published October 15, 2020 | https://doi.org/10.1371/journal.ppat.1008892

Invasive alien species and disease risk: An open challenge in public and animal health

Eleonora Chinchio, Matteo Crotta, Claudia Romeo, Julian A. Drewe, Javier Guitian, Nicola Ferrari

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008922

Some like it hot: Candida activation of inflammasomes

Giorgio Camilli, James S. Griffiths, Jemima Ho, Jonathan P. Richardson, Julian R. Naglik

PLOS Pathogens: published October 29, 2020 | https://doi.org/10.1371/journal.ppat.1008975

The prion-like phenomenon in Alzheimer’s disease: Evidence of pathology transmission in humans

Ruben Gomez-Gutierrez, Rodrigo Morales

PLOS Pathogens: published October 29, 2020 | https://doi.org/10.1371/journal.ppat.1009004

Dual-function quorum-sensing systems in bacterial pathogens and symbionts

Kelsey Barrasso, Samit Watve, Chelsea A. Simpson, Logan J. Geyman, Julia C. van Kessel, Wai-Leung Ng

PLOS Pathogens: published October 29, 2020 | https://doi.org/10.1371/journal.ppat.1008934

Preparedness needs research: How fundamental science and international collaboration accelerated the response to COVID-19

Cormac M. Kinsella, Pauline Dianne Santos, Ignacio Postigo-Hidalgo, Alba Folgueiras-González, Tim Casper Passchier, Kevin P. Szillat, Joyce Odeke Akello, Beatriz Álvarez-Rodríguez, Joan Martí-Carreras

PLOS Pathogens: published October 9, 2020 | https://doi.org/10.1371/journal.ppat.1008902

A molecular understanding of alphavirus entry

Autumn C. Holmes, Katherine Basore, Daved H. Fremont, Michael S. Diamond

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008876

Candida auris: Epidemiology, biology, antifungal resistance, and virulence

Han Du, Jian Bing, Tianren Hu, Craig L. Ennis, Clarissa J. Nobile, Guanghua Huang

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008921

The pneumococcal social network

Surya D. Aggarwal, Hasan Yesilkaya, Suzanne Dawid, N. Luisa Hiller

PLOS Pathogens: published October 29, 2020 | https://doi.org/10.1371/journal.ppat.1008931

The C4 protein encoded by tomato leaf curl Yunnan virus reverses transcriptional gene silencing by interacting with NbDRM2 and impairing its DNA-binding ability

Yuzhen Mei, Yaqin Wang, Fangfang Li, Xueping Zhou

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008829

Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

Pachiyappan Kamarajan, Islam Ateia, Jae M. Shin, J. Christopher Fenno, Charles Le, Ling Zhan, Ana Chang, Richard Darveau, Yvonne L. Kapila

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008881

STAT3 imparts BRCAness by impairing homologous recombination repair in Epstein-Barr virus-transformed B lymphocytes

Michael T. McIntosh, Siva Koganti, J. Lucas Boatwright, Xiaofan Li, Salvatore V. Spadaro, Alexis C. Brantly, Jasmine B. Ayers, Ramon D. Perez, Eric M. Burton, Sandeepta Burgula, Thomas MacCarthy, Sumita Bhaduri-McIntosh

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008849

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

Katharina Robichon, Tim Maiwald, Marcel Schilling, Annette Schneider, Joschka Willemsen, Florian Salopiata, Melissa Teusel, Clemens Kreutz, Christian Ehlting, Jun Huang, Sajib Chakraborty, Xiaoyun Huang, Georg Damm, Daniel Seehofer, Philipp A. Lang, Johannes G. Bode, Marco Binder, Ralf Bartenschlager, Jens Timmer, Ursula Klingmüller

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008461

Sclerotinia sclerotiorum utilizes host-derived copper for ROS detoxification and infection

Yijuan Ding, Jiaqin Mei, Yaru Chai, Wenjing Yang, Yi Mao, Baoqin Yan, Yang Yu, Joseph Onwusemu Disi, Kusum Rana, Jiana Li, Wei Qian

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008919

Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms

Emily R. Bowman, Cheryl M. Cameron, Brian Richardson, Manjusha Kulkarni, Janelle Gabriel, Morgan J. Cichon, Kenneth M. Riedl, Yousef Mustafa, Michael Cartwright, Brandon Snyder, Subha V. Raman, David A. Zidar, Susan L. Koletar, Martin P. Playford, Nehal N. Mehta, Scott F. Sieg, Michael L. Freeman, Michael M. Lederman, Mark J. Cameron, Nicholas T. Funderburg

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008869

Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation

Melanie Genoula, José Luis Marín Franco, Mariano Maio, Belén Dolotowicz, Malena Ferreyra, M. Ayelén Milillo, Rémi Mascarau, Eduardo José Moraña, Domingo Palmero, Mario Matteo, Federico Fuentes, Beatriz López, Paula Barrionuevo, Olivier Neyrolles, Céline Cougoule, Geanncarlo Lugo-Villarino, Christel Vérollet, María del Carmen Sasiain, Luciana Balboa

PLOS Pathogens: published October 1, 2020 | https://doi.org/10.1371/journal.ppat.1008929

Chaperone-tip adhesin complex is vital for synergistic activation of CFA/I fimbriae biogenesis

Li-hui He, Hao Wang, Yang Liu, Mei Kang, Tao Li, Chang-cheng Li, Ai-ping Tong, Yi-bo Zhu, Ying-jie Song, Stephen J. Savarino, Michael G. Prouty, Di Xia, Rui Bao

PLOS Pathogens: published October 2, 2020 | https://doi.org/10.1371/journal.ppat.1008848

Identification and characterisation of serotonin signalling in the potato cyst nematode Globodera pallida reveals new targets for crop protection

Anna Crisford, Fernando Calahorro, Elizabeth Ludlow, Jessica M. C. Marvin, Jennifer K. Hibbard, Catherine J. Lilley, James Kearn, Francesca Keefe, Peter Johnson, Rachael Harmer, Peter E. Urwin, Vincent O’Connor, Lindy Holden-Dye

PLOS Pathogens: published October 2, 2020 | https://doi.org/10.1371/journal.ppat.1008884

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

Daniele Veggi, Federica Bianchi, Laura Santini, Paola Lo Surdo, Chelsy C. Chesterman, Werner Pansegrau, Nicoletta Bechi, Ying Huang, Vega Masignani, Mariagrazia Pizza, Rino Rappuoli, Matthew J. Bottomley, Roberta Cozzi, Domenico Maione

PLOS Pathogens: published October 2, 2020 | https://doi.org/10.1371/journal.ppat.1008882

Novel Babesia bovis exported proteins that modify properties of infected red blood cells

Hassan Hakimi, Thomas J. Templeton, Miako Sakaguchi, Junya Yamagishi, Shinya Miyazaki, Kazuhide Yahata, Takayuki Uchihashi, Shin-ichiro Kawazu, Osamu Kaneko, Masahito Asada

PLOS Pathogens: published October 5, 2020 | https://doi.org/10.1371/journal.ppat.1008917

The transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress

Crispin Zavala-Alvarado, Odile Sismeiro, Rachel Legendre, Hugo Varet, Giovanni Bussotti, Jan Bayram, Samuel G. Huete, Guillaume Rey, Jean-Yves Coppée, Mathieu Picardeau, Nadia Benaroudj

PLOS Pathogens: published October 6, 2020 | https://doi.org/10.1371/journal.ppat.1008904

Lipopolysaccharide O structure of adherent and invasive Escherichia coli regulates intestinal inflammation via complement C3

Masashi Ohno, Mizuho Hasegawa, Atsushi Hayashi, Gustavo Caballero-Flores, Christopher J. Alteri, Trevor D. Lawley, Nobuhiko Kamada, Gabriel Núñez, Naohiro Inohara

PLOS Pathogens: published October 7, 2020 | https://doi.org/10.1371/journal.ppat.1008928

Murine cytomegaloviruses m139 targets DDX3 to curtail interferon production and promote viral replication

Olha Puhach, Eleonore Ostermann, Christoph Krisp, Giada Frascaroli, Hartmut Schlüter, Melanie M. Brinkmann, Wolfram Brune

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008546

Increased phagocytosis in the presence of enhanced M2-like macrophage responses correlates with increased primary and latent HSV-1 infection

Ujjaldeep Jaggi, Mingjie Yang, Harry H. Matundan, Satoshi Hirose, Prediman K. Shah, Behrooz G. Sharifi, Homayon Ghiasi

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008971

Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection

Emmeline L. Blanchard, Molly R. Braun, Aaron W. Lifland, Barbara Ludeke, Sarah L. Noton, Daryll Vanover, Chiara Zurla, Rachel Fearns, Philip J. Santangelo

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008987

Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis

Brigitta M. Laksono, Paola Fortugno, Bernadien M. Nijmeijer, Rory D. de Vries, Sonia Cordisco, Thijs Kuiken, Teunis B. H. Geijtenbeek, W. Paul Duprex, Francesco Brancati, Rik L. de Swart

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008253

The potyviral silencing suppressor HCPro recruits and employs host ARGONAUTE1 in pro-viral functions

Maija Pollari, Swarnalok De, Aiming Wang, Kristiina Mäkinen

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008965

Poxvirus-encoded decapping enzymes promote selective translation of viral mRNAs

Fernando Cantu, Shuai Cao, Candy Hernandez, Pragyesh Dhungel, Joshua Spradlin, Zhilong Yang

PLOS Pathogens: published October 8, 2020 | https://doi.org/10.1371/journal.ppat.1008926

Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity

Satoshi Ikegame, Shannon M. Beaty, Christian Stevens, Taylor Won, Arnold Park, David Sachs, Patrick Hong, Benhur Lee, Patricia A. Thibault

PLOS Pathogens: published October 9, 2020 | https://doi.org/10.1371/journal.ppat.1008877

Role reversal of functional identity in host factors: Dissecting features affecting pro-viral versus antiviral functions of cellular DEAD-box helicases in tombusvirus replication

Cheng-Yu Wu, Peter D. Nagy

PLOS Pathogens: published October 9, 2020 | https://doi.org/10.1371/journal.ppat.1008990

An intrinsic mechanism for coordinated production of the contact-dependent and contact-independent weapon systems in a soil bacterium

Mingming Yang, Shuangshuang Ren, Danyu Shen, Nianda Yang, Bingxin Wang, Sen Han, Xi Shen, Shan-Ho Chou, Guoliang Qian

PLOS Pathogens: published October 9, 2020 | https://doi.org/10.1371/journal.ppat.1008967

Antibody recognition of the Pneumovirus fusion protein trimer interface

Jiachen Huang, Darren Diaz, Jarrod J. Mousa

PLOS Pathogens: published October 9, 2020 | https://doi.org/10.1371/journal.ppat.1008942

Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis

Alexander Lercher, Alexandra M. Popa, Csilla Viczenczova, Lindsay Kosack, Kristaps Klavins, Benedikt Agerer, Christiane A. Opitz, Tobias V. Lanz, Michael Platten, Andreas Bergthaler

PLOS Pathogens: published October 12, 2020 | https://doi.org/10.1371/journal.ppat.1008973

BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis

Julia Holzerland, Lucie Fénéant, Logan Banadyga, Julia E. Hölper, Michael R. Knittler, Allison Groseth

PLOS Pathogens: published October 12, 2020 | https://doi.org/10.1371/journal.ppat.1008948

Fluorescent secreted bacterial effectors reveal active intravacuolar proliferation of Listeria monocytogenes in epithelial cells

Caroline Peron-Cane, José-Carlos Fernandez, Julien Leblanc, Laure Wingertsmann, Arnaud Gautier, Nicolas Desprat, Alice Lebreton

PLOS Pathogens: published October 12, 2020 | https://doi.org/10.1371/journal.ppat.1009001

The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae

Gregory L. Sousa, Ritika Bishnoi, Richard H. G. Baxter, Michael Povelones

PLOS Pathogens: published October 12, 2020 | https://doi.org/10.1371/journal.ppat.1008985

Association of host protein VARICOSE with HCPro within a multiprotein complex is crucial for RNA silencing suppression, translation, encapsidation and systemic spread of potato virus A infection

Swarnalok De, Maija Pollari, Markku Varjosalo, Kristiina Mäkinen

PLOS Pathogens: published October 12, 2020 | https://doi.org/10.1371/journal.ppat.1008956

Selective usage of ANP32 proteins by influenza B virus polymerase: Implications in determination of host range

Zhenyu Zhang, Haili Zhang, Ling Xu, Xing Guo, Wenfei Wang, Yujie Ji, Chaohui Lin, Yujie Wang, Xiaojun Wang

PLOS Pathogens: published October 12, 2020 | https://doi.org/10.1371/journal.ppat.1008989

Mining for humoral correlates of HIV control and latent reservoir size

Jishnu Das, Anush Devadhasan, Caitlyn Linde, Tom Broge, Jessica Sassic, Max Mangano, Sean O'Keefe, Todd Suscovich, Hendrik Streeck, Alivelu Irrinki, Chris Pohlmeyer, Gundula Min-Oo, Shu Lin, Joshua A. Weiner, Thomas Cihlar, Margaret E. Ackerman, Boris Julg, Steven Deeks, Douglas A. Lauffenburger, Galit Alter

PLOS Pathogens: published October 13, 2020 | https://doi.org/10.1371/journal.ppat.1008868

Wolbachia and Sirtuin-4 interaction is associated with alterations in host glucose metabolism and bacterial titer

Heverton Leandro Carneiro Dutra, Mark Anthony Deehan, Horacio Frydman

PLOS Pathogens: published October 13, 2020 | https://doi.org/10.1371/journal.ppat.1008996

YebC regulates variable surface antigen VlsE expression and is required for host immune evasion in Borrelia burgdorferi

Yan Zhang, Tong Chen, Sajith Raghunandanan, Xuwu Xiang, Jing Yang, Qiang Liu, Diane G. Edmondson, Steven J. Norris, X. Frank Yang, Yongliang Lou

PLOS Pathogens: published October 13, 2020 | https://doi.org/10.1371/journal.ppat.1008953

IL-27 signalling regulates glycolysis in Th1 cells to limit immunopathology during infection

Marcela Montes de Oca, Fabian de Labastida Rivera, Clay Winterford, Teija C. M. Frame, Susanna S. Ng, Fiona H. Amante, Chelsea L. Edwards, Luzia Bukali, Yulin Wang, Jude E. Uzonna, Rachel D. Kuns, Ping Zhang, Agnieszka Kabat, Ramon I. Klein Geltink, Edward J. Pearce, Geoffrey R. Hill, Christian R. Engwerda

PLOS Pathogens: published October 13, 2020 | https://doi.org/10.1371/journal.ppat.1008994

“The structure of the Type III secretion system export gate with CdsO, an ATPase lever arm”

Jaime L. Jensen, Shavait Yamini, Arne Rietsch, Benjamin W. Spiller

PLOS Pathogens: published October 13, 2020 | https://doi.org/10.1371/journal.ppat.1008923

HER2-mediated enhancement of Ebola virus entry

Makoto Kuroda, Peter Halfmann, Yoshihiro Kawaoka

PLOS Pathogens: published October 14, 2020 | https://doi.org/10.1371/journal.ppat.1008900

Reversion to ancestral Zika virus NS1 residues increases competence of Aedes albopictus

Lili Kuo, Anna S. Jaeger, Elyse M. Banker, Sean M. Bialosuknia, Nicholas Mathias, Anne F. Payne, Laura D. Kramer, Matthew T. Aliota, Alexander T. Ciota

PLOS Pathogens: published October 14, 2020 | https://doi.org/10.1371/journal.ppat.1008951

A non-canonical role for the autophagy machinery in anti-retroviral signaling mediated by TRIM5α

Bhaskar Saha, Devon Chisholm, Alison M. Kell, Michael A. Mandell

PLOS Pathogens: published October 14, 2020 | https://doi.org/10.1371/journal.ppat.1009017

Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

L. G. Webb, J. Veloz, J. Pintado-Silva, T. Zhu, M. V. Rangel, T. Mutetwa, L. Zhang, D. Bernal-Rubio, D. Figueroa, L. Carrau, R. Fenutria, U. Potla, St. P. Reid, J. S. Yount, K. A. Stapleford, S. Aguirre, A. Fernandez-Sesma

PLOS Pathogens: published October 15, 2020 | https://doi.org/10.1371/journal.ppat.1008999

KSHV G-protein coupled receptor vGPCR oncogenic signaling upregulation of Cyclooxygenase-2 expression mediates angiogenesis and tumorigenesis in Kaposi’s sarcoma

María Victoria Medina, Agata D´Agostino, Qi Ma, Pilar Eroles, Lucas Cavallin, Chiara Chiozzini, Daiana Sapochnik, Cora Cymeryng, Elizabeth Hyjek, Ethel Cesarman, Julian Naipauer, Enrique A. Mesri, Omar A. Coso

PLOS Pathogens: published October 15, 2020 | https://doi.org/10.1371/journal.ppat.1009006

Deciphering the molecular mechanisms of mother-to-egg immune protection in the mealworm beetle Tenebrio molitor

Guillaume Tetreau, Julien Dhinaut, Richard Galinier, Pascaline Audant-Lacour, Sébastien N. Voisin, Karim Arafah, Manon Chogne, Frédérique Hilliou, Anaïs Bordes, Camille Sabarly, Philippe Chan, Marie-Laure Walet-Balieu, David Vaudry, David Duval, Philippe Bulet, Christine Coustau, Yannick Moret, Benjamin Gourbal

PLOS Pathogens: published October 15, 2020 | https://doi.org/10.1371/journal.ppat.1008935

The NS1 protein of the parvovirus MVM Aids in the localization of the viral genome to cellular sites of DNA damage

Kinjal Majumder, Maria Boftsi, Fawn B. Whittle, Juexin Wang, Matthew S. Fuller, Trupti Joshi, David J. Pintel

PLOS Pathogens: published October 16, 2020 | https://doi.org/10.1371/journal.ppat.1009002

Qualitative Differences Between the IFNα subtypes and IFNβ Influence Chronic Mucosal HIV-1 Pathogenesis

Kejun Guo, Guannan Shen, Jon Kibbie, Tania Gonzalez, Stephanie M. Dillon, Harry A. Smith, Emily H. Cooper, Kerry Lavender, Kim J. Hasenkrug, Kathrin Sutter, Ulf Dittmer, Miranda Kroehl, Katerina Kechris, Cara C. Wilson, Mario L. Santiago

PLOS Pathogens: published October 16, 2020 | https://doi.org/10.1371/journal.ppat.1008986

RNA-based thermoregulation of a Campylobacter jejuni zinc resistance determinant

Heba Barnawi, Nader Masri, Natasha Hussain, Bushra Al-Lawati, Evita Mayasari, Aleksandra Gulbicka, Adrian J. Jervis, Min-Hsuan Huang, Jennifer S. Cavet, Dennis Linton

PLOS Pathogens: published October 16, 2020 | https://doi.org/10.1371/journal.ppat.1009008

Cellular co-infection can modulate the efficiency of influenza A virus production and shape the interferon response

Brigitte E. Martin, Jeremy D. Harris, Jiayi Sun, Katia Koelle, Christopher B. Brooke

PLOS Pathogens: published October 16, 2020 | https://doi.org/10.1371/journal.ppat.1008974

Feline calicivirus strain 2280 p30 antagonizes type I interferon-mediated antiviral innate immunity through directly degrading IFNAR1 mRNA

Jin Tian, Hongtao Kang, Jiapei Huang, Zhijie Li, Yudi Pan, Yin Li, Si Chen, Jikai Zhang, Hang Yin, Liandong Qu

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1008944

A non-enveloped arbovirus released in lysosome-derived extracellular vesicles induces super-infection exclusion

Thomas Labadie, Polly Roy

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1009015

Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2

Andrea J. French, Sekar Natesampillai, Ashton Krogman, Cristina Correia, Kevin L. Peterson, Alecia Alto, Aswath P. Chandrasekar, Anisha Misra, Ying Li, Scott H. Kaufmann, Andrew D. Badley, Nathan W. Cummins

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1008906

Analysis of KSHV B lymphocyte lineage tropism in human tonsil reveals efficient infection of CD138+ plasma cells

Farizeh Aalam, Romina Nabiee, Jesus Ramirez Castano, Jennifer Totonchy

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1008968

Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics

Béatrice Cambien, Kevin Lebrigand, Alberto Baeri, Nicolas Nottet, Catherine Compin, Audrey Lamit, Olivier Ferraris, Christophe N. Peyrefitte, Virginie Magnone, Jérôme Henriques, Laure-Emmanuelle Zaragosi, Sophie Giorgetti-Peraldi, Frédéric Bost, Marine Gautier-Isola, Roger Rezzonico, Pascal Barbry, Robert Barthel, Bernard Mari, Georges Vassaux

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1008660

Acinetobacter baumannii can use multiple siderophores for iron acquisition, but only acinetobactin is required for virulence

Jessica R. Sheldon, Eric P. Skaar

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1008995

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response

Rujapak Sutiwisesak, Nathan D. Hicks, Shayla Boyce, Kenan C. Murphy, Kadamba Papavinasasundaram, Stephen M. Carpenter, Julie Boucau, Neelambari Joshi, Sylvie Le Gall, Sarah M. Fortune, Christopher M. Sassetti, Samuel M. Behar

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1009000

Endothelin receptors promote schistosomiasis-induced hepatic fibrosis via splenic B cells

Hongyan Kong, Jinan He, Shusen Guo, Qiqin Song, Dandan Xiang, Ran Tao, Haijing Yu, Guang Chen, Zhiyong Huang, Qin Ning, Jiaquan Huang

PLOS Pathogens: published October 19, 2020 | https://doi.org/10.1371/journal.ppat.1008947

Biogenesis and molecular characteristics of serum hepatitis B virus RNA

Sheng Shen, Zhanglian Xie, Dawei Cai, Xiaoyang Yu, Hu Zhang, Elena S. Kim, Bin Zhou, Jinlin Hou, Xiaoyong Zhang, Qi Huang, Jian Sun, Haitao Guo

PLOS Pathogens: published October 20, 2020 | https://doi.org/10.1371/journal.ppat.1008945

p120 catenin recruits HPV to γ-secretase to promote virus infection

Mara Calypso Harwood, Allison Jade Dupzyk, Takamasa Inoue, Daniel DiMaio, Billy Tsai

PLOS Pathogens: published October 21, 2020 | https://doi.org/10.1371/journal.ppat.1008946

Gallbladder carriage generates genetic variation and genome degradation in Salmonella Typhi

Pham Thanh Duy, Nga Tran Vu Thieu, To Nguyen Thi Nguyen, Ho Ngoc Dan Thanh, Sabina Dongol, Abhilasha Karkey, Megan Carey, Buddha Basnyat, Gordon Dougan, Maia A. Rabaa, Stephen Baker

PLOS Pathogens: published October 21, 2020 | https://doi.org/10.1371/journal.ppat.1008998

Opsonized antigen activates Vδ2+ T cells via CD16/FCγRIIIa in individuals with chronic malaria exposure

Lila A. Farrington, Perri C. Callaway, Hilary M. Vance, Kayla Baskevitch, Emma Lutz, Lakshmi Warrier, Tara I. McIntyre, Rachel Budker, Prasanna Jagannathan, Felistas Nankya, Kenneth Musinguzi, Mayimuna Nalubega, Ester Sikyomu, Kate Naluwu, Emmanuel Arinaitwe, Grant Dorsey, Moses R. Kamya, Margaret E. Feeney

PLOS Pathogens: published October 21, 2020 | https://doi.org/10.1371/journal.ppat.1008997

Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes

Haowen Qiao, Moujian Guo, Jia Shang, Wen Zhao, Zhenyan Wang, Nian Liu, Bin Li, Ying Zhou, Ying Wu, Pu Chen

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008899

Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice

Elysia A. Masters, Karen L. de Mesy Bentley, Ann Lindley Gill, Stephanie P. Hao, Chad A. Galloway, Alec T. Salminen, Diamond R. Guy, James L. McGrath, Hani A. Awad, Steven R. Gill, Edward M. Schwarz

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008988

Role for the flagellum attachment zone in Leishmania anterior cell tip morphogenesis

Clare Halliday, Ryuji Yanase, Carolina Moura Costa Catta-Preta, Flavia Moreira-Leite, Jitka Myskova, Katerina Pruzinova, Petr Volf, Jeremy C. Mottram, Jack D. Sunter

PLOS Pathogens: published October 22, 2020 | https://doi.org/10.1371/journal.ppat.1008494

E2 ubiquitin-conjugating enzyme UBE2L6 promotes Senecavirus A proliferation by stabilizing the viral RNA polymerase

Liang Li, Juan Bai, Hui Fan, Junfang Yan, Shihai Li, Ping Jiang

PLOS Pathogens: published October 26, 2020 | https://doi.org/10.1371/journal.ppat.1008970

Effector prediction and characterization in the oomycete pathogen Bremia lactucae reveal host-recognized WY domain proteins that lack the canonical RXLR motif

Kelsey J. Wood, Munir Nur, Juliana Gil, Kyle Fletcher, Kim Lakeman, Dasan Gann, Ayumi Gothberg, Tina Khuu, Jennifer Kopetzky, Sanye Naqvi, Archana Pandya, Chi Zhang, Brigitte Maisonneuve, Mathieu Pel, Richard Michelmore

PLOS Pathogens: published October 26, 2020 | https://doi.org/10.1371/journal.ppat.1009012

Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation

Katherine M. Bricker, Veronica Obregon-Perko, Ferzan Uddin, Brianna Williams, Emilie A. Uffman, Carolina Garrido, Genevieve G. Fouda, Romas Geleziunas, Merlin Robb, Nelson Michael, Dan H. Barouch, Ann Chahroudi

PLOS Pathogens: published October 26, 2020 | https://doi.org/10.1371/journal.ppat.1008954

Actomyosin forces and the energetics of red blood cell invasion by the malaria parasite Plasmodium falciparum

Thomas C. A. Blake, Silvia Haase, Jake Baum

PLOS Pathogens: published October 26, 2020 | https://doi.org/10.1371/journal.ppat.1009007

MAVS regulates the quality of the antibody response to West-Nile Virus

Marvin O’Ketch, Spencer Williams, Cameron Larson, Jennifer L. Uhrlaub, Rachel Wong, Brenna Hall, Neha R. Deshpande, Dominik Schenten

PLOS Pathogens: published October 26, 2020 | https://doi.org/10.1371/journal.ppat.1009009

Dynamic metabolic reprogramming in dendritic cells: An early response to influenza infection that is essential for effector function

Svetlana Rezinciuc, Lavanya Bezavada, Azadeh Bahadoran, Susu Duan, Ruoning Wang, Daniel Lopez-Ferrer, David Finkelstein, Maureen A. McGargill, Douglas R. Green, Ljiljana Pasa-Tolic, Heather S. Smallwood

PLOS Pathogens: published October 26, 2020 | https://doi.org/10.1371/journal.ppat.1008957

Brucella suppress STING expression via miR-24 to enhance infection

Mike Khan, Jerome S. Harms, Yiping Liu, Jens Eickhoff, Jin Wen Tan, Tony Hu, Fengwei Cai, Erika Guimaraes, Sergio Costa Oliveira, Richard Dahl, Yong Cheng, Delia Gutman, Glen N. Barber, Gary A. Splitter, Judith A. Smith

PLOS Pathogens: published October 27, 2020 | https://doi.org/10.1371/journal.ppat.1009020

p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication

Xin Wang, Zhuanchang Wu, Yuming Li, Yifan Yang, Changguang Xiao, Xiqian Liu, Xiao Xiang, Jianchao Wei, Donghua Shao, Ke Liu, Xufang Deng, Jiaqiang Wu, Yafeng Qiu, Beibei Li, Zhiyong Ma

PLOS Pathogens: published October 27, 2020 | https://doi.org/10.1371/journal.ppat.1009035

Related Articles

1. Retraction: p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication

Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

Rebecca J. Burge, Andreas Damianou, Anthony J. Wilkinson, Boris Rodenko, Jeremy C. Mottram

PLOS Pathogens: published October 27, 2020 | https://doi.org/10.1371/journal.ppat.1008784

Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling

Katherine M. Still, Samantha J. Batista, Carleigh A. O’Brien, Oyebola O. Oyesola, Simon P. Früh, Lauren M. Webb, Igor Smirnov, Michael A. Kovacs, Maureen N. Cowan, Nikolas W. Hayes, Jeremy A. Thompson, Elia D. Tait Wojno, Tajie H. Harris

PLOS Pathogens: published October 27, 2020 | https://doi.org/10.1371/journal.ppat.1009027

Triclosan depletes the membrane potential in Pseudomonas aeruginosa biofilms inhibiting aminoglycoside induced adaptive resistance

Michael M. Maiden, Christopher M. Waters

PLOS Pathogens: published October 30, 2020 | https://doi.org/10.1371/journal.ppat.1008529

On the whereabouts of SARS-CoV-2 in the human body: A systematic review

Wim Trypsteen, Jolien Van Cleemput, Willem van Snippenberg, Sarah Gerlo, Linos Vandekerckhove

PLOS Pathogens: published October 30, 2020 | https://doi.org/10.1371/journal.ppat.1009037

Correction: Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network

Wan Li, Qingxia Wang, Qi Feng, Fei Wang, Yao Lu, Qin Yan, Shou-Jiang Gao, Chun Lu

PLOS Pathogens: published October 21, 2020 | https://doi.org/10.1371/journal.ppat.1009039

Related Articles

1. Oncogenic KSHV-encoded interferon regulatory factor upregulates HMGB2 and CMPK1 expression to promote cell invasion by disrupting a complex lncRNA-OIP5-AS1/miR-218-5p network

Correction: Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

Mark Achtman, John Wain, François-Xavier Weill, Satheesh Nair, Zhemin Zhou, Vartul Sangal, Mary G. Krauland, James L. Hale, Heather Harbottle, Alexandra Uesbeck, Gordon Dougan, Lee H. Harrison, Sylvain Brisse, the S. enterica MLST study group

PLOS Pathogens: published October 21, 2020 | https://doi.org/10.1371/journal.ppat.1009040

Related Articles

1. Multilocus Sequence Typing as a Replacement for Serotyping in Salmonella enterica

Correction: Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid

Luca Ferretti, Eva Pérez-Martín, Fuquan Zhang, François Maree, Lin-Mari de Klerk-Lorist, Louis van Schalkwykc, Nicholas D. Juleff, Bryan Charleston, Paolo Ribeca

PLOS Pathogens: published October 28, 2020 | https://doi.org/10.1371/journal.ppat.1009050

Related Articles

1. Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid

Correction: Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease

Artur Santos-Miranda, Julliane Vasconcelos Joviano-Santos, Grazielle Alves Ribeiro, Ana Flávia M. Botelho, Peter Rocha, Leda Quercia Vieira, Jader Santos Cruz, Danilo Roman-Campos

PLOS Pathogens: published October 28, 2020 | https://doi.org/10.1371/journal.ppat.1009049

Related Articles

1. Reactive oxygen species and nitric oxide imbalances lead to in vivo and in vitro arrhythmogenic phenotype in acute phase of experimental Chagas disease

Retraction: A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice

The PLOS Pathogens Editors

PLOS Pathogens: published October 21, 2020 | https://doi.org/10.1371/journal.ppat.1009031

Related Articles

1. A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice