No more business as usual: Agile and effective responses to emerging pathogen threats require open data and open analytics

Dannon Baker, Marius van den Beek, Daniel Blankenberg, Dave Bouvier, John Chilton, Nate Coraor, Frederik Coppens, Ignacio Eguinoa, Simon Gladman, Björn Grüning, Nicholas Keener, Delphine Larivière, Andrew Lonie, Sergei Kosakovsky Pond, Wolfgang Maier, Anton Nekrutenko, James Taylor, Steven Weaver

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008643

African swine fever whole-genome sequencing—Quantity wanted but quality needed

Jan H. Forth, Leonie F. Forth, Sandra Blome, Dirk Höper, Martin Beer

PLOS Pathogens: published August 27, 2020 | https://doi.org/10.1371/journal.ppat.1008779

Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides

R. A. Leo Elworth, Christian Diaz, Jing Yang, Paul de Figueiredo, Krista Ternus, Todd Treangen

PLOS Pathogens: published August 6, 2020 | https://doi.org/10.1371/journal.ppat.1008649

Intracellular antibody immunity and its applications

Jingwei Zeng, Leo C. James

PLOS Pathogens: published August 6, 2020 | https://doi.org/10.1371/journal.ppat.1008657

Convalescent serum therapy for COVID-19: A 19th century remedy for a 21st century disease

Daniel Montelongo-Jauregui, Taissa Vila, Ahmed S. Sultan, Mary Ann Jabra-Rizk

PLOS Pathogens: published August 12, 2020 | https://doi.org/10.1371/journal.ppat.1008735

Beyond tug-of-war: Iron metabolism in cooperative host–microbe interactions

Grischa Y. Chen, Janelle S. Ayres

PLOS Pathogens: published August 12, 2020 | https://doi.org/10.1371/journal.ppat.1008698

They are what you eat: Shaping of viral populations through nutrition and consequences for virulence

Rebekah Honce, Stacey Schultz-Cherry

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008711

The intriguing world of archaeal viruses

Jennifer Wirth, Mark Young

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008574

Catch the wave: Metabolomic analyses in human pathogenic fungi

Philipp Brandt, Enrico Garbe, Slavena Vylkova

PLOS Pathogens: published August 20, 2020 | https://doi.org/10.1371/journal.ppat.1008757

Post-tuberculosis chronic pulmonary aspergillosis: An emerging public health concern

Felix Bongomin

PLOS Pathogens: published August 20, 2020 | https://doi.org/10.1371/journal.ppat.1008742

The later stages of viral infection: An undiscovered country of host dependency factors

Cason R. King, Andrew Mehle

PLOS Pathogens: published August 25, 2020 | https://doi.org/10.1371/journal.ppat.1008777

COVID-19 real-world data for the US and lessons to reopen business

Pascal J. Goldschmidt-Clermont

PLOS Pathogens: published August 27, 2020 | https://doi.org/10.1371/journal.ppat.1008756

Lymph nodes—The neglected battlefield in tuberculosis

Sharie Keanne C. Ganchua, Alexander G. White, Edwin C. Klein, JoAnne L. Flynn

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008632

COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2

Anshumali Mittal, Kavyashree Manjunath, Rajesh Kumar Ranjan, Sandeep Kaushik, Sujeet Kumar, Vikash Verma

PLOS Pathogens: published August 21, 2020 | https://doi.org/10.1371/journal.ppat.1008762

Friends or foes? The knowns and unknowns of natural killer cell biology in COVID-19 and other coronaviruses in July 2020

Cordelia Manickam, Sho Sugawara, R. Keith Reeves

PLOS Pathogens: published August 26, 2020 | https://doi.org/10.1371/journal.ppat.1008820

Circumpolar diversification of the Ixodes uriae tick virome

John H.-O. Pettersson, Patrik Ellström, Jiaxin Ling, Ingela Nilsson, Sven Bergström, Daniel González-Acuña, Björn Olsen, Edward C. Holmes

PLOS Pathogens: published August 3, 2020 | https://doi.org/10.1371/journal.ppat.1008759

Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step

Xiaohua Ye, Hang Su, Daniel Wrapp, Daniel C. Freed, Fengsheng Li, Zihao Yuan, Aimin Tang, Leike Li, Zhiqiang Ku, Wei Xiong, Dabbu Jaijyan, Hua Zhu, Dai Wang, Jason S. McLellan, Ningyan Zhang, Tong-Ming Fu, Zhiqiang An

PLOS Pathogens: published August 3, 2020 | https://doi.org/10.1371/journal.ppat.1008736

Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4⁺ T cells post peptide loading

Katherine S. Forsyth, Nathan H. Roy, Elise Peauroi, Brian C. DeHaven, Erik D. Wold, Adam R. Hersperger, Janis K. Burkhardt, Laurence C. Eisenlohr

PLOS Pathogens: published August 3, 2020 | https://doi.org/10.1371/journal.ppat.1008685

Genomic and transcriptomic evidence for descent from Plasmodium and loss of blood schizogony in Hepatocystis parasites from naturally infected red colobus monkeys

Eerik Aunin, Ulrike Böhme, Theo Sanderson, Noah D. Simons, Tony L. Goldberg, Nelson Ting, Colin A. Chapman, Chris I. Newbold, Matthew Berriman, Adam J. Reid

PLOS Pathogens: published August 3, 2020 | https://doi.org/10.1371/journal.ppat.1008717

Intracellular neutralisation of rotavirus by VP6-specific IgG

Sarah L. Caddy, Marina Vaysburd, Mark Wing, Stian Foss, Jan Terje Andersen, Kevin O‘Connell, Keith Mayes, Katie Higginson, Miren Iturriza-Gómara, Ulrich Desselberger, Leo C. James

PLOS Pathogens: published August 4, 2020 | https://doi.org/10.1371/journal.ppat.1008732

Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection

Timothy M. Tucey, Jiyoti Verma, Françios A. B. Olivier, Tricia L. Lo, Avril A. B. Robertson, Thomas Naderer, Ana Traven

PLOS Pathogens: published August 4, 2020 | https://doi.org/10.1371/journal.ppat.1008695

Galectin-3 enhances neutrophil motility and extravasation into the airways during Aspergillus fumigatus infection

Brendan D. Snarr, Guillaume St-Pierre, Benjamin Ralph, Mélanie Lehoux, Yukiko Sato, Ann Rancourt, Takahiro Takazono, Shane R. Baistrocchi, Rachel Corsini, Matthew P. Cheng, Michele Sugrue, Lindsey R. Baden, Koichi Izumikawa, Hiroshi Mukae, John R. Wingard, Irah L. King, Maziar Divangahi, Masahiko S. Satoh, Bryan G. Yipp, Sachiko Sato, Donald C. Sheppard

PLOS Pathogens: published August 4, 2020 | https://doi.org/10.1371/journal.ppat.1008741

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8⁺ T cells

Sneha Sant, Sergio M. Quiñones-Parra, Marios Koutsakos, Emma J. Grant, Thomas Loudovaris, Stuart I. Mannering, Jane Crowe, Carolien E. van de Sandt, Guus F. Rimmelzwaan, Jamie Rossjohn, Stephanie Gras, Liyen Loh, Thi H. O. Nguyen, Katherine Kedzierska

PLOS Pathogens: published August 4, 2020 | https://doi.org/10.1371/journal.ppat.1008714

Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control

Bruna Oriol-Tordera, Maria Berdasco, Anuska Llano, Beatriz Mothe, Cristina Gálvez, Javier Martinez-Picado, Jorge Carrillo, Julià Blanco, Clara Duran-Castells, Carmela Ganoza, Jorge Sanchez, Bonaventura Clotet, Maria Luz Calle, Alex Sánchez-Pla, Manel Esteller, Christian Brander, Marta Ruiz-Riol

PLOS Pathogens: published August 6, 2020 | https://doi.org/10.1371/journal.ppat.1008678

Selective Upregulation of CTLA-4 on CD8⁺ T Cells Restricted by HLA-B*35Px Renders them to an Exhausted Phenotype in HIV-1 infection

Shokrollah Elahi, Shima Shahbaz, Stan Houston

PLOS Pathogens: published August 6, 2020 | https://doi.org/10.1371/journal.ppat.1008696

Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells

Matteo Bosso, Caterina Prelli Bozzo, Dominik Hotter, Meta Volcic, Christina M. Stürzel, Annika Rammelt, Yi Ni, Stephan Urban, Miriam Becker, Mario Schelhaas, Sabine Wittmann, Maria H. Christensen, Florian I. Schmidt, Thomas Gramberg, Konstantin M. J. Sparrer, Daniel Sauter, Frank Kirchhoff

PLOS Pathogens: published August 6, 2020 | https://doi.org/10.1371/journal.ppat.1008752

A cross-reactive antibody protects against Ross River virus musculoskeletal disease despite rapid neutralization escape in mice

Julie M. Fox, Ling Huang, Stephen Tahan, Laura A. Powell, James E. Crowe Jr., David Wang, Michael S. Diamond

PLOS Pathogens: published August 6, 2020 | https://doi.org/10.1371/journal.ppat.1008743

Genomic Surveillance of Yellow Fever Virus Epizootic in São Paulo, Brazil, 2016 – 2018

Sarah C. Hill, Renato de Souza, Julien Thézé, Ingra Claro, Renato S. Aguiar, Leandro Abade, Fabiana C. P. Santos, Mariana S. Cunha, Juliana S. Nogueira, Flavia C. S. Salles, Iray M. Rocco, Adriana Y. Maeda, Fernanda G. S. Vasami, Louis du Plessis, Paola P. Silveira, Jaqueline G. de Jesus, Joshua Quick, Natália C. C. A. Fernandes, Juliana M. Guerra, Rodrigo A. Réssio, Marta Giovanetti, Luiz C. J. Alcantara, Cinthya S. Cirqueira, Josué Díaz-Delgado, Fernando L. L. Macedo, Maria do Carmo S. T. Timenetsky, Regiane de Paula, Roberta Spinola, Juliana Telles de Deus, Luís F. Mucci, Rosa Maria Tubaki, Regiane M. T. de Menezes, Patrícia L. Ramos, Andre L. de Abreu, Laura N. Cruz, Nick Loman, Simon Dellicour, Oliver G. Pybus, Ester C. Sabino, Nuno R. Faria

PLOS Pathogens: published August 7, 2020 | https://doi.org/10.1371/journal.ppat.1008699

Host-derived circular RNAs display proviral activities in Hepatitis C virus-infected cells

Tzu-Chun Chen, Marc Tallo-Parra, Qian M. Cao, Sebastian Kadener, René Böttcher, Gemma Pérez-Vilaró, Pakpoom Boonchuen, Kunlaya Somboonwiwat, Juana Díez, Peter Sarnow

PLOS Pathogens: published August 7, 2020 | https://doi.org/10.1371/journal.ppat.1008346

Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue

Jan Bayram, Ivana Malcova, Larisa Sinkovec, Jana Holubova, Gaia Streparola, David Jurnecka, Jan Kucera, Radislav Sedlacek, Peter Sebo, Jana Kamanova

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008512

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles

Clifton L. Ricana, Terri D. Lyddon, Robert A. Dick, Marc C. Johnson

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008646

The complex pattern of genetic associations of leprosy with HLA class I and class II alleles can be reduced to four amino acid positions

Monica Dallmann-Sauer, Vinicius M. Fava, Chaïma Gzara, Marianna Orlova, Nguyen Van Thuc, Vu Hong Thai, Alexandre Alcaïs, Laurent Abel, Aurélie Cobat, Erwin Schurr

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008818

Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast

Allison K. Scherer, Bailey A. Blair, Jieun Park, Brittany G. Seman, Joshua B. Kelley, Robert T. Wheeler

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008414

JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glands

Avisha Chowdhury, Cassandra M. Modahl, Siok Thing Tan, Benjamin Wong Wei Xiang, Dorothée Missé, Thomas Vial, R. Manjunatha Kini, Julien Francis Pompon

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008754

A HSV1 mutant leads to an attenuated phenotype and induces immunity with a protective effect

Xingli Xu, Xiao Feng, Lichun Wang, Ting Yi, Lichun Zheng, Guorun Jiang, Shengtao Fan, Yun Liao, Min Feng, Ying Zhang, Dandan Li, Qihan Li

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008703

Resistance to Bacillus thuringiensis Cry1Ac toxin requires mutations in two Plutella xylostella ATP-binding cassette transporter paralogs

Zhaoxia Liu, Shu Fu, Xiaoli Ma, Simon W. Baxter, Liette Vasseur, Lei Xiong, Yuping Huang, Guang Yang, Shijun You, Minsheng You

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008697

Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway

Wan Li, Fei Wang, Jiale Shi, Qi Feng, Yuheng Chen, Xiaoyu Qi, Cong Wang, Hongmei Lu, Zhongmou Lu, Xuemei Jia, Qin Yan, Shou-Jiang Gao, Chun Lu

PLOS Pathogens: published August 10, 2020 | https://doi.org/10.1371/journal.ppat.1008730

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1. Correction: Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway

Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens

Aleksandar Antanasijevic, George Ueda, Philip J. M. Brouwer, Jeffrey Copps, Deli Huang, Joel D. Allen, Christopher A. Cottrell, Anila Yasmeen, Leigh M. Sewall, Ilja Bontjer, Thomas J. Ketas, Hannah L. Turner, Zachary T. Berndsen, David C. Montefiori, Per Johan Klasse, Max Crispin, David Nemazee, John P. Moore, Rogier W. Sanders, Neil P. King, David Baker, Andrew B. Ward

PLOS Pathogens: published August 11, 2020 | https://doi.org/10.1371/journal.ppat.1008665

Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza

Claire Scott, Jayakanth Kankanala, Toshana L. Foster, Daniel H. Goldhill, Peng Bao, Katie Simmons, Marieke Pingen, Matthew Bentham, Elizabeth Atkins, Eleni Loundras, Ruth Elderfield, Jolyon K. Claridge, Joseph Thompson, Peter R. Stilwell, Ranjitha Tathineni, Clive S. McKimmie, Paul Targett-Adams, Jason R. Schnell, Graham P. Cook, Stephen Evans, Wendy S. Barclay, Richard Foster, Stephen Griffin

PLOS Pathogens: published August 11, 2020 | https://doi.org/10.1371/journal.ppat.1008716

MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation

Wangshu Jiang, Wimal Ubhayasekera, Michael C. Breed, Allison N. Norsworthy, Nina Serr, Harry L. T. Mobley, Melanie M. Pearson, Stefan D. Knight

PLOS Pathogens: published August 11, 2020 | https://doi.org/10.1371/journal.ppat.1008707

Downy Mildew effector HaRxL21 interacts with the transcriptional repressor TOPLESS to promote pathogen susceptibility

Sarah Harvey, Priyanka Kumari, Dmitry Lapin, Thomas Griebel, Richard Hickman, Wenbin Guo, Runxuan Zhang, Jane E. Parker, Jim Beynon, Katherine Denby, Jens Steinbrenner

PLOS Pathogens: published August 12, 2020 | https://doi.org/10.1371/journal.ppat.1008835

Rho factor mediates flagellum and toxin phase variation and impacts virulence in Clostridioides difficile

Dominika Trzilova, Brandon R. Anjuwon-Foster, Dariana Torres Rivera, Rita Tamayo

PLOS Pathogens: published August 12, 2020 | https://doi.org/10.1371/journal.ppat.1008708

Fingolimod inhibits multiple stages of the HIV-1 life cycle

Rachel S. Resop, Rémi Fromentin, Daniel Newman, Hawley Rigsby, Larisa Dubrovsky, Michael Bukrinsky, Nicolas Chomont, Alberto Bosque

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008679

Leptospiral LPS escapes mouse TLR4 internalization and TRIF‑associated antimicrobial responses through O antigen and associated lipoproteins

Delphine Bonhomme, Ignacio Santecchia, Frédérique Vernel-Pauillac, Martine Caroff, Pierre Germon, Gerald Murray, Ben Adler, Ivo G. Boneca, Catherine Werts

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008639

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1. Correction: Leptospiral LPS escapes mouse TLR4 internalization and TRIF-associated antimicrobial responses through O antigen and associated lipoproteins

Cell type- and replication stage-specific influenza virus responses in vivo

Elizabeth J. Fay, Stephanie L. Aron, Marissa G. Macchietto, Matthew W. Markman, Katharina Esser-Nobis, Michael Gale Jr, Steven Shen, Ryan A. Langlois

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008760

The pneumococcal two-component system SirRH is linked to enhanced intracellular survival of Streptococcus pneumoniae in influenza-infected pulmonary cells

Nicolás M. Reinoso-Vizcaíno, Melina B. Cian, Paulo R. Cortes, Nadia B. Olivero, Mirelys Hernandez-Morfa, Germán E. Piñas, Chandan Badapanda, Ankita Rathore, Daniel R. Perez, José Echenique

PLOS Pathogens: published August 13, 2020 | https://doi.org/10.1371/journal.ppat.1008761

CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes

Danielle A. S. Rodrigues, Elisa B. Prestes, Andreza M. S. Gama, Leandro de Souza Silva, Ana Acácia S. Pinheiro, Jose Marcos C. Ribeiro, Raquel M. P. Campos, Pedro M. Pimentel-Coelho, Heitor S. De Souza, Alassane Dicko, Patrick E. Duffy, Michal Fried, Ivo M. B. Francischetti, Elvira M. Saraiva, Heitor A. Paula-Neto, Marcelo T. Bozza

PLOS Pathogens: published August 14, 2020 | https://doi.org/10.1371/journal.ppat.1008230

Footprint of the host restriction factors APOBEC3 on the genome of human viruses

Florian Poulain, Noémie Lejeune, Kévin Willemart, Nicolas A. Gillet

PLOS Pathogens: published August 14, 2020 | https://doi.org/10.1371/journal.ppat.1008718

CRISPR/Cas with ribonucleoprotein complexes and transiently selected telomere vectors allows highly efficient marker-free and multiple genome editing in Botrytis cinerea

Thomas Leisen, Fabian Bietz, Janina Werner, Alex Wegner, Ulrich Schaffrath, David Scheuring, Felix Willmund, Andreas Mosbach, Gabriel Scalliet, Matthias Hahn

PLOS Pathogens: published August 17, 2020 | https://doi.org/10.1371/journal.ppat.1008326

Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state

Claudia Antoni, Dennis Quentin, Alexander E. Lang, Klaus Aktories, Christos Gatsogiannis, Stefan Raunser

PLOS Pathogens: published August 18, 2020 | https://doi.org/10.1371/journal.ppat.1008530

Gene expression network analyses during infection with virulent and avirulent Trypanosoma cruzi strains unveil a role for fibroblasts in neutrophil recruitment and activation

Antonio Edson R. Oliveira, Milton C. A. Pereira, Ashton T. Belew, Ludmila R. P. Ferreira, Larissa M. N. Pereira, Eula G. A. Neves, Maria do Carmo P. Nunes, Barbara A. Burleigh, Walderez O. Dutra, Najib M. El-Sayed, Ricardo T. Gazzinelli, Santuza M. R. Teixeira

PLOS Pathogens: published August 18, 2020 | https://doi.org/10.1371/journal.ppat.1008781

Genetic analysis reveals long-standing population differentiation and high diversity in the rust pathogen Melampsora lini

Hanna Susi, Jeremy J. Burdon, Peter H. Thrall, Adnane Nemri, Luke G. Barrett

PLOS Pathogens: published August 18, 2020 | https://doi.org/10.1371/journal.ppat.1008731

Human papillomavirus type 38 alters wild-type p53 activity to promote cell proliferation via the downregulation of integrin alpha 1 expression

Maria Carmen Romero-Medina, Assunta Venuti, Giusi Melita, Alexis Robitaille, Maria Grazia Ceraolo, Laura Pacini, Cecilia Sirand, Daniele Viarisio, Valerio Taverniti, Purnima Gupta, Mariafrancesca Scalise, Cesare Indiveri, Rosita Accardi, Massimo Tommasino

PLOS Pathogens: published August 19, 2020 | https://doi.org/10.1371/journal.ppat.1008792

Evolution-guided mutagenesis of the cytoplasmic incompatibility proteins: Identifying CifA’s complex functional repertoire and new essential regions in CifB

J. Dylan Shropshire, Mahip Kalra, Seth R. Bordenstein

PLOS Pathogens: published August 19, 2020 | https://doi.org/10.1371/journal.ppat.1008794

The α-tubulin of Laodelphax striatellus mediates the passage of rice stripe virus (RSV) and enhances horizontal transmission

Yao Li, Danyu Chen, Jia Hu, Kun Zhang, Lin Kang, Yan Chen, Lijun Huang, Lu Zhang, Yin Xiang, Qisheng Song, Fang Liu

PLOS Pathogens: published August 20, 2020 | https://doi.org/10.1371/journal.ppat.1008710

Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy

Marissa J. Paterson, JR Caldera, Christopher Nguyen, Purnima Sharma, Anthony M. Castro, Stacey L. Kolar, Chih-Ming Tsai, Jose J. Limon, Courtney A. Becker, Gislâine A. Martins, George Y. Liu, David M. Underhill

PLOS Pathogens: published August 20, 2020 | https://doi.org/10.1371/journal.ppat.1008733

Sterol 14-α-demethylase is vital for mitochondrial functions and stress tolerance in Leishmania major

Sumit Mukherjee, Samrat Moitra, Wei Xu, Veronica Hernandez, Kai Zhang

PLOS Pathogens: published August 20, 2020 | https://doi.org/10.1371/journal.ppat.1008810

A-to-I RNA editing in bacteria increases pathogenicity and tolerance to oxidative stress

Wenhan Nie, Sai Wang, Rui He, Qin Xu, Peihong Wang, Yan Wu, Fang Tian, Junhua Yuan, Bo Zhu, Gongyou Chen

PLOS Pathogens: published August 21, 2020 | https://doi.org/10.1371/journal.ppat.1008740

Modulation of hepatitis B virus pregenomic RNA stability and splicing by histone deacetylase 5 enhances viral biosynthesis

Taha Y. Taha, Varada Anirudhan, Umaporn Limothai, Daniel D. Loeb, Pavel A. Petukhov, Alan McLachlan

PLOS Pathogens: published August 21, 2020 | https://doi.org/10.1371/journal.ppat.1008802

Genetic variation in the MacAB-TolC efflux pump influences pathogenesis of invasive Salmonella isolates from Africa

Jared D. Honeycutt, Nicolas Wenner, Yan Li, Susan M. Brewer, Liliana M. Massis, Sky W. Brubaker, Phoom Chairatana, Siân V. Owen, Rocío Canals, Jay C. D. Hinton, Denise M. Monack

PLOS Pathogens: published August 24, 2020 | https://doi.org/10.1371/journal.ppat.1008763

High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms

Manja Czech-Sioli, Thomas Günther, Marlin Therre, Michael Spohn, Daniela Indenbirken, Juliane Theiss, Sabine Riethdorf, Minyue Qi, Malik Alawi, Corinna Wülbeck, Irene Fernandez-Cuesta, Franziska Esmek, Jürgen C. Becker, Adam Grundhoff, Nicole Fischer

PLOS Pathogens: published August 24, 2020 | https://doi.org/10.1371/journal.ppat.1008562

Global exploration of the metabolic requirements of gallid alphaherpesvirus 1

Yangyang Qiao, Zhitao Wang, Zongxi Han, Yuhao Shao, Yong Ma, Yumeng Liang, Zhijie Chen, Hanguang Wu, Lu Cui, Yanhui Zhang, Shengwang Liu, Hai Li

PLOS Pathogens: published August 24, 2020 | https://doi.org/10.1371/journal.ppat.1008815

A tyrosine phosphoregulatory system controls exopolysaccharide biosynthesis and biofilm formation in Vibrio cholerae

Carmen Schwechheimer, Kassidy Hebert, Sarvind Tripathi, Praveen K. Singh, Kyle A. Floyd, Elise R. Brown, Monique E. Porcella, Jacqueline Osorio, Joseph T. M. Kiblen, Fernando A. Pagliai, Knut Drescher, Seth M. Rubin, Fitnat H. Yildiz

PLOS Pathogens: published August 25, 2020 | https://doi.org/10.1371/journal.ppat.1008745

Cells producing residual viremia during antiretroviral treatment appear to contribute to rebound viremia following interruption of treatment

Hadega A. Aamer, Jan McClure, Daisy Ko, Janine Maenza, Ann C. Collier, Robert W. Coombs, James I. Mullins, Lisa M. Frenkel

PLOS Pathogens: published August 25, 2020 | https://doi.org/10.1371/journal.ppat.1008791

Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses

Guillaume N. Fiches, Dawei Zhou, Weili Kong, Ayan Biswas, Elshafa H. Ahmed, Robert A. Baiocchi, Jian Zhu, Netty Santoso

PLOS Pathogens: published August 25, 2020 | https://doi.org/10.1371/journal.ppat.1008778

Characterization of a novel AraC/XylS-regulated family of N-acyltransferases in pathogens of the order Enterobacterales

Laura Belmont-Monroy, Waleska Saitz-Rojas, Jorge Soria-Bustos, Abigail S. Mickey, Nicholas E. Sherman, Benjamin C. Orsburn, Fernando Ruiz-Perez, Araceli E. Santiago

PLOS Pathogens: published August 26, 2020 | https://doi.org/10.1371/journal.ppat.1008776

Copper primes adaptation of uropathogenic Escherichia coli to superoxide stress by activating superoxide dismutases

Panatda Saenkham, Matthew Ritter, George L. Donati, Sargurunathan Subashchandrabose

PLOS Pathogens: published August 26, 2020 | https://doi.org/10.1371/journal.ppat.1008856

Prion protein signaling induces M2 macrophage polarization and protects from lethal influenza infection in mice

Junji Chida, Hideyuki Hara, Keiji Uchiyama, Etsuhisa Takahashi, Hironori Miyata, Hidetaka Kosako, Yukiko Tomioka, Toshihiro Ito, Hiroyuki Horiuchi, Haruo Matsuda, Hiroshi Kido, Suehiro Sakaguchi

PLOS Pathogens: published August 26, 2020 | https://doi.org/10.1371/journal.ppat.1008823

Development and evaluation of a rapid CRISPR-based diagnostic for COVID-19

Tieying Hou, Weiqi Zeng, Minling Yang, Wenjing Chen, Lili Ren, Jingwen Ai, Ji Wu, Yalong Liao, Xuejing Gou, Yongjun Li, Xiaorui Wang, Hang Su, Bing Gu, Jianwei Wang, Teng Xu

PLOS Pathogens: published August 27, 2020 | https://doi.org/10.1371/journal.ppat.1008705

Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin

Wenjuan Du, Margreet A. Wolfert, Ben Peeters, Frank J. M. van Kuppeveld, Geert-Jan Boons, Erik de Vries, Cornelis A. M. de Haan

PLOS Pathogens: published August 27, 2020 | https://doi.org/10.1371/journal.ppat.1008816

Structural insight into the membrane targeting domain of the Legionella deAMPylase SidD

Igor Tascón, Xiao Li, María Lucas, D’anna Nelson, Ander Vidaurrazaga, Yi-Han Lin, Adriana L. Rojas, Aitor Hierro, Matthias P. Machner

PLOS Pathogens: published August 27, 2020 | https://doi.org/10.1371/journal.ppat.1008734

Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

Angel K. Kongsomboonvech, Felipe Rodriguez, Anh L. Diep, Brandon M. Justice, Brayan E. Castallanos, Ana Camejo, Debanjan Mukhopadhyay, Gregory A. Taylor, Masahiro Yamamoto, Jeroen P. J. Saeij, Michael L. Reese, Kirk D. C. Jensen

PLOS Pathogens: published August 27, 2020 | https://doi.org/10.1371/journal.ppat.1008327

YAP in epithelium senses gut barrier loss to deploy defenses against pathogens

Yi-Cheng Ma, Zhong-Shan Yang, Lan-Qing Ma, Ran Shu, Cheng-Gang Zou, Ke-Qin Zhang

PLOS Pathogens: published August 28, 2020 | https://doi.org/10.1371/journal.ppat.1008766

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections

Saleem Alameh, Gloria Bartolo, Summer O’Brien, Elizabeth A. Henderson, Leandra O. Gonzalez, Stella Hartmann, Christopher P. Klimko, Jennifer L. Shoe, Christopher K. Cote, Laurence K. Grill, Anastasia Levitin, Mikhail Martchenko Shilman

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008836

Overlapping and distinct roles of CDPK family members in the pre-erythrocytic stages of the rodent malaria parasite, Plasmodium berghei

Kavitha Govindasamy, Purnima Bhanot

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008131

Discrete spatio-temporal regulation of tyrosine phosphorylation directs influenza A virus M1 protein towards its function in virion assembly

Angeles Mecate-Zambrano, Swathi Sukumar, Guiscard Seebohm, Kevin Ciminski, André Schreiber, Darisuren Anhlan, Lilo Greune, Ludmilla Wixler, Stephanie Grothe, Nora Caroline Stein, M. Alexander Schmidt, Klaus Langer, Martin Schwemmle, Tianlai Shi, Stephan Ludwig, Yvonne Boergeling

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008775

Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape

Yuen-Yan Chang, Virginie Stévenin, Magalie Duchateau, Quentin Giai Gianetto, Veronique Hourdel, Cristina Dias Rodrigues, Mariette Matondo, Norbert Reiling, Jost Enninga

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008822

Rice stripe virus suppresses jasmonic acid-mediated resistance by hijacking brassinosteroid signaling pathway in rice

Jinlong Hu, Jie Huang, Haosen Xu, Yongsheng Wang, Chen Li, Peizheng Wen, Xiaoman You, Xiao Zhang, Gen Pan, Qi Li, Hongliang Zhang, Jun He, Hongming Wu, Ling Jiang, Haiyang Wang, Yuqiang Liu, Jianmin Wan

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008801

Distinct disease features in chimpanzees infected with a precore HBV mutant associated with acute liver failure in humans

Zhaochun Chen, Ronald E. Engle, Chen-Hsiang Shen, Huaying Zhao, Peter W. Schuck, Emily J. Danoff, Hanh Nguyen, Norihisa Nishimura, Kevin W. Bock, Ian N. Moore, Peter D. Kwong, Robert H. Purcell, Sugantha Govindarajan, Patrizia Farci

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008793

Babesia bovis Rad51 ortholog influences switching of ves genes but is not essential for segmental gene conversion in antigenic variation

Erin A. Mack, Massimiliano S. Tagliamonte, Yu-Ping Xiao, Samantha Quesada, David R. Allred

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008772

Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells

Chen Peng, Linda S. Wyatt, Shira G. Glushakow-Smith, Madhu Lal-Nag, Andrea S. Weisberg, Bernard Moss

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008845

Ubiquitin-Like protein 5 interacts with the silencing suppressor p3 of rice stripe virus and mediates its degradation through the 26S proteasome pathway

Binghua Chen, Lin Lin, Yuwen Lu, Jiejun Peng, Hongying Zheng, Qiankun Yang, Shaofei Rao, Guanwei Wu, Junmin Li, Zhuo Chen, Baoan Song, Jianping Chen, Fei Yan

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008780

Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates

Christopher A. Cottrell, Jelle van Schooten, Charles A. Bowman, Meng Yuan, David Oyen, Mia Shin, Robert Morpurgo, Patricia van der Woude, Mariëlle van Breemen, Jonathan L. Torres, Raj Patel, Justin Gross, Leigh M. Sewall, Jeffrey Copps, Gabriel Ozorowski, Bartek Nogal, Devin Sok, Eva G. Rakasz, Celia Labranche, Vladimir Vigdorovich, Scott Christley, Diane G. Carnathan, D. Noah Sather, David Montefiori, Guido Silvestri, Dennis R. Burton, John P. Moore, Ian A. Wilson, Rogier W. Sanders, Andrew B. Ward, Marit J. van Gils

PLOS Pathogens: published August 31, 2020 | https://doi.org/10.1371/journal.ppat.1008753

Correction: Antigenic evolution of viruses in host populations

Igor M. Rouzine, Ganna Rozhnova

PLOS Pathogens: published August 12, 2020 | https://doi.org/10.1371/journal.ppat.1008830

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