Virus interactions with bacteria: Partners in the infectious dance

Ursula Neu, Bernardo A. Mainou

PLOS Pathogens: published February 11, 2020 | https://doi.org/10.1371/journal.ppat.1008234

Evolution of microsporidia: An extremely successful group of eukaryotic intracellular parasites

Lina Wadi, Aaron W. Reinke

PLOS Pathogens: published February 13, 2020 | https://doi.org/10.1371/journal.ppat.1008276

Diverse alveolate infections of tadpoles, a new threat to frogs?

Aurelie Chambouvet, Vanessa Smilansky, Miloslav Jirků, Marcos Isidoro-Ayza, Sarah Itoïz, Evelyne Derelle, Adam Monier, David J. Gower, Mark Wilkinson, Michael J. Yabsley, Julius Lukeš, Thomas A. Richards

PLOS Pathogens: published February 13, 2020 | https://doi.org/10.1371/journal.ppat.1008107

Evolving moldy murderers: Aspergillus section Fumigati as a model for studying the repeated evolution of fungal pathogenicity

Antonis Rokas, Matthew E. Mead, Jacob L. Steenwyk, Nicholas H. Oberlies, Gustavo H. Goldman

PLOS Pathogens: published February 27, 2020 | https://doi.org/10.1371/journal.ppat.1008315

The enigmatic mechanisms by which Plasmodium vivax infects Duffy-negative individuals

Jean Popovici, Camille Roesch, Virginie Rougeron

PLOS Pathogens: published February 20, 2020 | https://doi.org/10.1371/journal.ppat.1008258

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection

Benoit Stijlemans, Hannelie Korf, Patrick De Baetselier, Lea Brys, Jo A. Van Ginderachter, Stefan Magez, Carl De Trez

PLOS Pathogens: published February 3, 2020 | https://doi.org/10.1371/journal.ppat.1008170

Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy

Amanda L. Woerman, Smita Patel, Sabeen A. Kazmi, Abby Oehler, Jisoo Lee, Daniel A. Mordes, Steven H. Olson, Stanley B. Prusiner

PLOS Pathogens: published February 4, 2020 | https://doi.org/10.1371/journal.ppat.1008222

Selective reconstitution of IFN‑γ gene function in Ncr1⁺ NK cells is sufficient to control systemic vaccinia virus infection

Katharina Borst, Sven Flindt, Patrick Blank, Pia-Katharina Larsen, Chintan Chhatbar, Jennifer Skerra, Julia Spanier, Christoph Hirche, Martin König, Tomas Alanentalo, Martin Hafner, Zoe Waibler, Klaus Pfeffer, Veronika Sexl, Gerd Sutter, Werner Müller, Theresa Graalmann, Ulrich Kalinke

PLOS Pathogens: published February 5, 2020 | https://doi.org/10.1371/journal.ppat.1008279

Dynamics of HIV DNA reservoir seeding in a cohort of superinfected Kenyan women

Mark D. Pankau, Daniel B. Reeves, Elias Harkins, Keshet Ronen, Walter Jaoko, Kishor Mandaliya, Susan M. Graham, R. Scott McClelland, Frederick A. Matsen IV, Joshua T. Schiffer, Julie Overbaugh, Dara A. Lehman

PLOS Pathogens: published February 5, 2020 | https://doi.org/10.1371/journal.ppat.1008286

Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand

Morgane Rolland, Sodsai Tovanabutra, Bethany Dearlove, Yifan Li, Christopher L. Owen, Eric Lewitus, Eric Sanders-Buell, Meera Bose, AnneMarie O’Sullivan, Raabya Rossenkhan, Jan Phillipus Lourens Labuschagne, Paul T. Edlefsen, Daniel B. Reeves, Gustavo Kijak, Shana Miller, Kultida Poltavee, Jenica Lee, Lydia Bonar, Elizabeth Harbolick, Bahar Ahani, Phuc Pham, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fred K. Sawe, Leigh Anne Eller, Robert Gramzinski, Jerome H. Kim, Nelson L. Michael, Merlin L. Robb, the RV217 Study Team

PLOS Pathogens: published February 6, 2020 | https://doi.org/10.1371/journal.ppat.1008179

USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I

Xinyue Tao, Bei Chu, Di Xin, Lin Li, Qinmiao Sun

PLOS Pathogens: published February 6, 2020 | https://doi.org/10.1371/journal.ppat.1008293

“Submergence” of Western equine encephalitis virus: Evidence of positive selection argues against genetic drift and fitness reductions

Nicholas A. Bergren, Sherry Haller, Shannan L. Rossi, Robert L. Seymour, Jing Huang, Aaron L. Miller, Richard A. Bowen, Daniel A. Hartman, Aaron C. Brault, Scott C. Weaver

PLOS Pathogens: published February 6, 2020 | https://doi.org/10.1371/journal.ppat.1008102

RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters

Ella Hartenian, Sarah Gilbertson, Joel D. Federspiel, Ileana M. Cristea, Britt A. Glaunsinger

PLOS Pathogens: published February 7, 2020 | https://doi.org/10.1371/journal.ppat.1008269

Hantavirus inhibits apoptosis by preventing mitochondrial membrane potential loss through up-regulation of the pro-survival factor BCL-2

Carles Solà-Riera, Marina García, Hans-Gustaf Ljunggren, Jonas Klingström

PLOS Pathogens: published February 7, 2020 | https://doi.org/10.1371/journal.ppat.1008297

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

Brendon M. Lee, Liam K. Harold, Deepak V. Almeida, Livnat Afriat-Jurnou, Htin Lin Aung, Brian M. Forde, Kiel Hards, Sacha J. Pidot, F. Hafna Ahmed, A. Elaaf Mohamed, Matthew C. Taylor, Nicholas P. West, Timothy P. Stinear, Chris Greening, Scott A. Beatson, Eric L. Nuermberger, Gregory M. Cook, Colin J. Jackson

PLOS Pathogens: published February 7, 2020 | https://doi.org/10.1371/journal.ppat.1008287

A live auxotrophic vaccine confers mucosal immunity and protection against lethal pneumonia caused by Pseudomonas aeruginosa

Maria P. Cabral, Alexandra Correia, Manuel Vilanova, Fátima Gärtner, Miriam Moscoso, Patricia García, Juan A. Vallejo, Astrid Pérez, Mónica Francisco-Tomé, Víctor Fuentes-Valverde, Germán Bou

PLOS Pathogens: published February 10, 2020 | https://doi.org/10.1371/journal.ppat.1008311

HIV protease cleaves the antiviral m⁶A reader protein YTHDF3 in the viral particle

Denise Jurczyszak, Wen Zhang, Sandra N. Terry, Thomas Kehrer, Maria C. Bermúdez González, Emma McGregor, Lubbertus C. F. Mulder, Matthew J. Eckwahl, Tao Pan, Viviana Simon

PLOS Pathogens: published February 13, 2020 | https://doi.org/10.1371/journal.ppat.1008305

Interferon-stimulated gene 20 (ISG20) selectively degrades N6-methyladenosine modified Hepatitis B Virus transcripts

Hasan Imam, Geon-Woo Kim, Saiful Anam Mir, Mohsin Khan, Aleem Siddiqui

PLOS Pathogens: published February 14, 2020 | https://doi.org/10.1371/journal.ppat.1008338

A mevalonate bypass system facilitates elucidation of plastid biology in malaria parasites

Russell P. Swift, Krithika Rajaram, Hans B. Liu, Amanda Dziedzic, Anne E. Jedlicka, Aleah D. Roberts, Krista A. Matthews, Hugo Jhun, Namandje N. Bumpus, Shivendra G. Tewari, Anders Wallqvist, Sean T. Prigge

PLOS Pathogens: published February 14, 2020 | https://doi.org/10.1371/journal.ppat.1008316

Intrahost cytomegalovirus population genetics following antibody pretreatment in a monkey model of congenital transmission

Diana Vera Cruz, Cody S. Nelson, Dollnovan Tran, Peter A. Barry, Amitinder Kaur, Katia Koelle, Sallie R. Permar

PLOS Pathogens: published February 14, 2020 | https://doi.org/10.1371/journal.ppat.1007968

B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection

James C. Romero-Masters, Shane M. Huebner, Makoto Ohashi, Jillian A. Bristol, Bayleigh E. Benner, Elizabeth A. Barlow, Gail L. Turk, Scott E. Nelson, Dana C. Baiu, Nicholas Van Sciver, Erik A. Ranheim, Jenny Gumperz, Nathan M. Sherer, Paul J. Farrell, Eric C. Johannsen, Shannon C. Kenney

PLOS Pathogens: published February 14, 2020 | https://doi.org/10.1371/journal.ppat.1008365

Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host

Samit Watve, Kelsey Barrasso, Sarah A. Jung, Kristen J. Davis, Lisa A. Hawver, Atul Khataokar, Ryan G. Palaganas, Matthew B. Neiditch, Lark J. Perez, Wai-Leung Ng

PLOS Pathogens: published February 14, 2020 | https://doi.org/10.1371/journal.ppat.1008313

A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni

Mona Alzheimer, Sarah L. Svensson, Fabian König, Matthias Schweinlin, Marco Metzger, Heike Walles, Cynthia M. Sharma

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008304

Novel role of SARM1 mediated axonal degeneration in the pathogenesis of rabies

Vinod Sundaramoorthy, Diane Green, Kelly Locke, Carmel M. O’Brien, Megan Dearnley, John Bingham

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008343

TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis

Ainhoa Arbués, Dominique Brees, Salah-Dine Chibout, Todd Fox, Michael Kammüller, Damien Portevin

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008312

Structure of the host cell recognition and penetration machinery of a Staphylococcus aureus bacteriophage

James L. Kizziah, Keith A. Manning, Altaira D. Dearborn, Terje Dokland

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008314

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis

Lei Zhang, R. Curtis Hendrickson, Virginia Meikle, Elliot J. Lefkowitz, Thomas R. Ioerger, Michael Niederweis

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008337

An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing

Raymond W. Wong, Ahalya Balachandran, Peter K. Cheung, Ran Cheng, Qun Pan, Peter Stoilov, P. Richard Harrigan, Benjamin J. Blencowe, Donald R. Branch, Alan Cochrane

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008307

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Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross

Ankit Gupta, Abdullah A. B. Bokhari, Ajay D. Pillai, Anna K. Crater, Jeanine Gezelle, Gagandeep Saggu, Armiyaw S. Nasamu, Suresh M. Ganesan, Jacquin C. Niles, Sanjay A. Desai

PLOS Pathogens: published February 18, 2020 | https://doi.org/10.1371/journal.ppat.1008363

Chitin and chitosan remodeling defines vegetative development and Trichoderma biocontrol

Lisa Kappel, Martin Münsterkötter, György Sipos, Carolina Escobar Rodriguez, Sabine Gruber

PLOS Pathogens: published February 20, 2020 | https://doi.org/10.1371/journal.ppat.1008320

The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication

Tri Nguyen, Sohyoung Lee, Yi-An Yang, Changhwan Ahn, Ji Hyun Sim, Tiffany G. Kei, Karen N. Barnard, Hai Yu, Shawn K. Millano, Xi Chen, Colin R. Parrish, Jeongmin Song

PLOS Pathogens: published February 21, 2020 | https://doi.org/10.1371/journal.ppat.1008336

A unique feature of swine ANP32A provides susceptibility to avian influenza virus infection in pigs

Haili Zhang, Hongxin Li, Wenqiang Wang, Yujie Wang, Guan-Zhu Han, Hualan Chen, Xiaojun Wang

PLOS Pathogens: published February 21, 2020 | https://doi.org/10.1371/journal.ppat.1008330

Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion

Charles A. Coomer, Irene Carlon-Andres, Maro Iliopoulou, Michael L. Dustin, Ewoud B. Compeer, Alex A. Compton, Sergi Padilla-Parra

PLOS Pathogens: published February 21, 2020 | https://doi.org/10.1371/journal.ppat.1008359

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Cryo-EM structure of the Shigella type III needle complex

Michele Lunelli, Antje Kamprad, Jörg Bürger, Thorsten Mielke, Christian M. T. Spahn, Michael Kolbe

PLOS Pathogens: published February 24, 2020 | https://doi.org/10.1371/journal.ppat.1008263

Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies

Thach H. Chu, Andrew R. Crowley, Iara Backes, Cheryl Chang, Matthew Tay, Thomas Broge, Marina Tuyishime, Guido Ferrari, Michael S. Seaman, Simone I. Richardson, Georgia D. Tomaras, Galit Alter, David Leib, Margaret E. Ackerman

PLOS Pathogens: published February 24, 2020 | https://doi.org/10.1371/journal.ppat.1008083

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Phosphoinositide-binding proteins mark, shape and functionally modulate highly-diverged endocytic compartments in the parasitic protist Giardia lamblia

Lenka Cernikova, Carmen Faso, Adrian B. Hehl

PLOS Pathogens: published February 24, 2020 | https://doi.org/10.1371/journal.ppat.1008317

Quantitative proteomics analysis reveals important roles of N-glycosylation on ER quality control system for development and pathogenesis in Magnaporthe oryzae

Xiao-Lin Chen, Caiyun Liu, Bozeng Tang, Zhiyong Ren, Guo-Liang Wang, Wende Liu

PLOS Pathogens: published February 24, 2020 | https://doi.org/10.1371/journal.ppat.1008355

Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway

Chandrima Gain, Samaresh Malik, Shaoni Bhattacharjee, Arijit Ghosh, Erle S. Robertson, Benu Brata Das, Abhik Saha

PLOS Pathogens: published February 24, 2020 | https://doi.org/10.1371/journal.ppat.1008105

Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity

Anika Singanayagam, Jie Zhou, Ruth A. Elderfield, Rebecca Frise, Jonathan Ashcroft, Monica Galiano, Shahjahan Miah, Laura Nicolaou, Wendy S. Barclay

PLOS Pathogens: published February 25, 2020 | https://doi.org/10.1371/journal.ppat.1008362

Two waves of pro-inflammatory factors are released during the influenza A virus (IAV)-driven pulmonary immunopathogenesis

Junsong Zhang, Jun Liu, Yaochang Yuan, Feng Huang, Rong Ma, Baohong Luo, Zhihui Xi, Ting Pan, Bingfeng Liu, Yiwen Zhang, Xu Zhang, Yuewen Luo, Jin Wang, Meng Zhao, Gen Lu, Kai Deng, Hui Zhang

PLOS Pathogens: published February 26, 2020 | https://doi.org/10.1371/journal.ppat.1008334

VCAM1/VLA4 interaction mediates Ly6C^low monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection

Donglei Sun, Mingshun Zhang, Peng Sun, Gongguan Liu, Ashley B. Strickland, Yanli Chen, Yong Fu, Mohammed Yosri, Meiqing Shi

PLOS Pathogens: published February 26, 2020 | https://doi.org/10.1371/journal.ppat.1008361

Viral infection triggers interferon-induced expulsion of live Cryptococcus neoformans by macrophages

Paula I. Seoane, Leanne M. Taylor-Smith, David Stirling, Lucy C. K. Bell, Mahdad Noursadeghi, Dalan Bailey, Robin C. May

PLOS Pathogens: published February 27, 2020 | https://doi.org/10.1371/journal.ppat.1008240

Sirtuin 1 regulates mitochondrial function and immune homeostasis in respiratory syncytial virus infected dendritic cells

Srikanth Elesela, Susan B. Morris, Samanthi Narayanan, Surinder Kumar, David B. Lombard, Nicholas W. Lukacs

PLOS Pathogens: published February 27, 2020 | https://doi.org/10.1371/journal.ppat.1008319

The oxidative fumarase FumC is a key contributor for E. coli fitness under iron-limitation and during UTI

Stephanie D. Himpsl, Allyson E. Shea, Jonathan Zora, Jolie A. Stocki, Dannielle Foreman, Christopher J. Alteri, Harry L. T. Mobley

PLOS Pathogens: published February 27, 2020 | https://doi.org/10.1371/journal.ppat.1008382

Diverse effects of interferon alpha on the establishment and reversal of HIV latency

Renée M. Van der Sluis, Jennifer M. Zerbato, Jake W. Rhodes, Rachel D. Pascoe, Ajantha Solomon, Nitasha A. Kumar, Ashanti I. Dantanarayana, Surekha Tennakoon, Jérémy Dufloo, James McMahon, Judy J. Chang, Vanessa A. Evans, Paul J. Hertzog, Martin R. Jakobsen, Andrew N. Harman, Sharon R. Lewin, Paul U. Cameron

PLOS Pathogens: published February 28, 2020 | https://doi.org/10.1371/journal.ppat.1008151

Reovirus uses macropinocytosis-mediated entry and fast axonal transport to infect neurons

Pavithra Aravamudhan, Krishnan Raghunathan, Jennifer Konopka-Anstadt, Amrita Pathak, Danica M. Sutherland, Bruce D. Carter, Terence S. Dermody

PLOS Pathogens: published February 28, 2020 | https://doi.org/10.1371/journal.ppat.1008380

Correction: Induction of PGRN by influenza virus inhibits the antiviral immune responses through downregulation of type I interferons signaling

Fanhua Wei, Zhimin Jiang, Honglei Sun, Juan Pu, Yipeng Sun, Mingyang Wang, Qi Tong, Yuhai Bi, Xiaojing Ma, George Fu Gao, Jinhua Liu

PLOS Pathogens: published February 3, 2020 | https://doi.org/10.1371/journal.ppat.1008321

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Correction: Salmonella escapes adaptive immune response via SIRT2 mediated modulation of innate immune response in dendritic cells

Mayuri Gogoi, Kasturi Chandra, Mohsen Sarikhani, Ramya Ramani, Nagalingam Ravi Sundaresan, Dipshikha Chakravortty

PLOS Pathogens: published February 5, 2020 | https://doi.org/10.1371/journal.ppat.1008345

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