PLOS Pathogens 2018 Reviewer and Editorial Board Thank You

PLOS Pathogens: published February 27, 2019 | https://doi.org/10.1371/journal.ppat.1007649

Cyclic diguanylate riboswitches control bacterial pathogenesis mechanisms

Rita Tamayo

PLOS Pathogens: published February 7, 2019 | https://doi.org/10.1371/journal.ppat.1007529

The founder hypothesis: A basis for microbiota resistance, diversity in taxa carriage, and colonization resistance against pathogens

Yael Litvak, Andreas J. Bäumler

PLOS Pathogens: published February 21, 2019 | https://doi.org/10.1371/journal.ppat.1007563

Killing two birds with one stone: How the respiratory syncytial virus polymerase initiates transcription and replication

Sarah L. Noton, Chadene Z. Tremaglio, Rachel Fearns

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007548

Casting a wider net: Immunosurveillance by nonclassical MHC molecules

M. Patricia D’Souza, Erin Adams, John D. Altman, Michael E. Birnbaum, Cesar Boggiano, Giulia Casorati, Yueh-hsiu Chien, Anthony Conley, Sidonia Barbara Guiomar Eckle, Klaus Früh, Timothy Gondré-Lewis, Namir Hassan, Huang Huang, Lakshmi Jayashankar, Anne G. Kasmar, Nina Kunwar, Judith Lavelle, David M. Lewinsohn, Branch Moody, Louis Picker, Lakshmi Ramachandra, Nilabh Shastri, Peter Parham, Andrew J. McMichael, Jonathan W. Yewdell

PLOS Pathogens: published February 21, 2019 | https://doi.org/10.1371/journal.ppat.1007567

An anti-Gn glycoprotein antibody from a convalescent patient potently inhibits the infection of severe fever with thrombocytopenia syndrome virus

Ki Hyun Kim, Jinhee Kim, Meehyun Ko, June Young Chun, Hyori Kim, Seungtaek Kim, Ji-Young Min, Wan Beom Park, Myoung-don Oh, Junho Chung

PLOS Pathogens: published February 1, 2019 | https://doi.org/10.1371/journal.ppat.1007375

Plant-parasitic nematodes respond to root exudate signals with host-specific gene expression patterns

Christopher A. Bell, Catherine J. Lilley, James McCarthy, Howard J. Atkinson, P. E. Urwin

PLOS Pathogens: published February 1, 2019 | https://doi.org/10.1371/journal.ppat.1007503

Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming

Ryan P. McNamara, Pauline E. Chugh, Aubrey Bailey, Lindsey M. Costantini, Zhe Ma, Rachele Bigi, Avery Cheves, Anthony B. Eason, Justin T. Landis, Kurtis M. Host, Jie Xiong, Jack D. Griffith, Blossom Damania, Dirk P. Dittmer

PLOS Pathogens: published February 4, 2019 | https://doi.org/10.1371/journal.ppat.1007536

Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques

Huihui Chong, Jing Xue, Yuanmei Zhu, Zhe Cong, Ting Chen, Qiang Wei, Chuan Qin, Yuxian He

PLOS Pathogens: published February 4, 2019 | https://doi.org/10.1371/journal.ppat.1007552

MUC1 is a receptor for the Salmonella SiiE adhesin that enables apical invasion into enterocytes

Xinyue Li, Nancy M. C. Bleumink-Pluym, Yvette M. C. A. Luijkx, Richard W. Wubbolts, Jos P. M. van Putten, Karin Strijbis

PLOS Pathogens: published February 4, 2019 | https://doi.org/10.1371/journal.ppat.1007566

Potassium response and homeostasis in Mycobacterium tuberculosis modulates environmental adaptation and is important for host colonization

Nathan J. MacGilvary, Yuzo L. Kevorkian, Shumin Tan

PLOS Pathogens: published February 4, 2019 | https://doi.org/10.1371/journal.ppat.1007591

The polymeric immunoglobulin receptor-like protein from Marsupenaeus japonicus is a receptor for white spot syndrome virus infection

Guo-Juan Niu, Shuai Wang, Ji-Dong Xu, Ming-Chong Yang, Jie-Jie Sun, Zhong-Hua He, Xiao-Fan Zhao, Jin-Xing Wang

PLOS Pathogens: published February 6, 2019 | https://doi.org/10.1371/journal.ppat.1007558

TLR4 signaling improves PD-1 blockade therapy during chronic viral infection

Yidan Wang, Young Rock Chung, Simon Eitzinger, Nicole Palacio, Shana Gregory, Mitra Bhattacharyya, Pablo Penaloza-MacMaster

PLOS Pathogens: published February 6, 2019 | https://doi.org/10.1371/journal.ppat.1007583

The acidic domain of the hepatitis C virus NS4A protein is required for viral assembly and envelopment through interactions with the viral E1 glycoprotein

Allison E. Roder, Christine Vazquez, Stacy M. Horner

PLOS Pathogens: published February 7, 2019 | https://doi.org/10.1371/journal.ppat.1007163

Absence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds

Henan Zhu, Batchuluun Damdinjav, Gaelle Gonzalez, Livia Victoria Patrono, Humberto Ramirez-Mendoza, Julien A. R. Amat, Joanna Crispell, Yasmin Amy Parr, Toni-ann Hammond, Enkhtuvshin Shiilegdamba, Y. H. Connie Leung, Malik Peiris, John F. Marshall, Joseph Hughes, Martin Gilbert, Pablo R. Murcia

PLOS Pathogens: published February 7, 2019 | https://doi.org/10.1371/journal.ppat.1007531

PIKfyve/Fab1 is required for efficient V-ATPase and hydrolase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection

Catherine M. Buckley, Victoria L. Heath, Aurélie Guého, Cristina Bosmani, Paulina Knobloch, Phumzile Sikakana, Nicolas Personnic, Stephen K. Dove, Robert H. Michell, Roger Meier, Hubert Hilbi, Thierry Soldati, Robert H. Insall, Jason S. King

PLOS Pathogens: published February 7, 2019 | https://doi.org/10.1371/journal.ppat.1007551

The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit

Dan F. Young, Elizabeth B. Wignall-Fleming, David C. Busse, Matthew J. Pickin, Jacqueline Hankinson, Elizabeth M. Randall, Amy Tavendale, Andrew J. Davison, Douglas Lamont, John S. Tregoning, Steve Goodbourn, Richard E. Randall

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007561

PolyGlcNAc-containing exopolymers enable surface penetration by non-motile Enterococcus faecalis

Yusibeska Ramos, Jorge Rocha, Ana L. Hael, Jordi van Gestel, Hera Vlamakis, Colette Cywes-Bentley, Juan R. Cubillos-Ruiz, Gerald B. Pier, Michael S. Gilmore, Roberto Kolter, Diana K. Morales

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007571

TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection

Katsuhisa Masaki, Yoshifumi Sonobe, Ghanashyam Ghadge, Peter Pytel, Raymond P. Roos

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007574

The tyrosine transporter of Toxoplasma gondii is a member of the newly defined apicomplexan amino acid transporter (ApiAT) family

Kathryn E. R. Parker, Stephen J. Fairweather, Esther Rajendran, Martin Blume, Malcolm J. McConville, Stefan Bröer, Kiaran Kirk, Giel G. van Dooren

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007577

The 14-3-3η chaperone protein promotes antiviral innate immunity via facilitating MDA5 oligomerization and intracellular redistribution

Jhih-Pu Lin, Yu-Kuan Fan, Helene Minyi Liu

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007582

Rational design of a live-attenuated eastern equine encephalitis virus vaccine through informed mutation of virulence determinants

Derek W. Trobaugh, Chengqun Sun, Matthew D. Dunn, Douglas S. Reed, William B. Klimstra

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007584

Neisseria gonorrhoeae evades autophagic killing by downregulating CD46-cyt1 and remodeling lysosomes

Won J. Kim, Annette Mai, Nathan J. Weyand, Maria A. Rendón, Koenraad Van Doorslaer, Magdalene So

PLOS Pathogens: published February 12, 2019 | https://doi.org/10.1371/journal.ppat.1007495

The transcription factor NHR-8: A new target to increase ivermectin efficacy in nematodes

Cécile Ménez, Mélanie Alberich, Elise Courtot, Fabrice Guegnard, Alexandra Blanchard, Hugo Aguilaniu, Anne Lespine

PLOS Pathogens: published February 13, 2019 | https://doi.org/10.1371/journal.ppat.1007598

A high rate of polymerization during synthesis of mouse mammary tumor virus DNA alleviates hypermutation by APOBEC3 proteins

Benedikt Hagen, Martin Kraase, Ivana Indikova, Stanislav Indik

PLOS Pathogens: published February 15, 2019 | https://doi.org/10.1371/journal.ppat.1007533

Cyclical adaptation of measles virus quasispecies to epithelial and lymphocytic cells: To V, or not to V

Ryan C. Donohue, Christian K. Pfaller, Roberto Cattaneo

PLOS Pathogens: published February 15, 2019 | https://doi.org/10.1371/journal.ppat.1007605

A poxvirus pseudokinase represses viral DNA replication via a pathway antagonized by its paralog kinase

Annabel T. Olson, Zhigang Wang, Amber B. Rico, Matthew S. Wiebe

PLOS Pathogens: published February 15, 2019 | https://doi.org/10.1371/journal.ppat.1007608

Identification of HIV gp41-specific antibodies that mediate killing of infected cells

Katherine L. Williams, Megan Stumpf, Nicole Elise Naiman, Shilei Ding, Meghan Garrett, Theodore Gobillot, Dani Vézina, Katharine Dusenbury, Nitya S. Ramadoss, Ryan Basom, Peter S. Kim, Andrés Finzi, Julie Overbaugh

PLOS Pathogens: published February 19, 2019 | https://doi.org/10.1371/journal.ppat.1007572

EhFP10: A FYVE family GEF interacts with myosin IB to regulate cytoskeletal dynamics during endocytosis in Entamoeba histolytica

Gunjan Gautam, Mohammad Sabir Ali, Alok Bhattacharya, Samudrala Gourinath

PLOS Pathogens: published February 19, 2019 | https://doi.org/10.1371/journal.ppat.1007573

Picornavirus infection induces temporal release of multiple extracellular vesicle subsets that differ in molecular composition and infectious potential

Susanne G. van der Grein, Kyra A. Y. Defourny, Huib H. Rabouw, Chenna R. Galiveti, Martijn A. Langereis, Marca H. M. Wauben, Ger J. A. Arkesteijn, Frank J. M. van Kuppeveld, Esther N. M. Nolte-‘t Hoen

PLOS Pathogens: published February 19, 2019 | https://doi.org/10.1371/journal.ppat.1007594

Human IFIT proteins inhibit lytic replication of KSHV: A new feed-forward loop in the innate immune system

Dajiang Li, Sankar Swaminathan

PLOS Pathogens: published February 19, 2019 | https://doi.org/10.1371/journal.ppat.1007609

Atomic structures and deletion mutant reveal different capsid-binding patterns and functional significance of tegument protein pp150 in murine and human cytomegaloviruses with implications for therapeutic development

Wei Liu, Xinghong Dai, Jonathan Jih, Karen Chan, Phong Trang, Xuekui Yu, Rilwan Balogun, Ye Mei, Fenyong Liu, Z. Hong Zhou

PLOS Pathogens: published February 19, 2019 | https://doi.org/10.1371/journal.ppat.1007615

Kaposi’s sarcoma-associated herpesvirus ORF57 protein protects viral transcripts from specific nuclear RNA decay pathways by preventing hMTR4 recruitment

Julio C. Ruiz, Olga V. Hunter, Nicholas K. Conrad

PLOS Pathogens: published February 20, 2019 | https://doi.org/10.1371/journal.ppat.1007596

Plant begomoviruses subvert ubiquitination to suppress plant defenses against insect vectors

Ping Li, Chao Liu, Wen-Hao Deng, Dan-Mei Yao, Li-Long Pan, Yun-Qin Li, Yin-Quan Liu, Yan Liang, Xue-Ping Zhou, Xiao-Wei Wang

PLOS Pathogens: published February 21, 2019 | https://doi.org/10.1371/journal.ppat.1007607

The seven transmembrane domain protein MoRgs7 functions in surface perception and undergoes coronin MoCrn1-dependent endocytosis in complex with Gα subunit MoMagA to promote cAMP signaling and appressorium formation in Magnaporthe oryzae

Xiao Li, Kaili Zhong, Ziyi Yin, Jiexiong Hu, Wenhao Wang, Lianwei Li, Haifeng Zhang, Xiaobo Zheng, Ping Wang, Zhengguang Zhang

PLOS Pathogens: published February 25, 2019 | https://doi.org/10.1371/journal.ppat.1007382

PML nuclear body-residing proteins sequentially associate with HPV genome after infectious nuclear delivery

Lucile Guion, Malgorzata Bienkowska-Haba, Stephen DiGiuseppe, Luise Florin, Martin Sapp

PLOS Pathogens: published February 25, 2019 | https://doi.org/10.1371/journal.ppat.1007590

Modulation of calcium signaling pathway by hepatitis C virus core protein stimulates NLRP3 inflammasome activation

Amina A. Negash, Rebecca M. Olson, Stephen Griffin, Michael Gale Jr

PLOS Pathogens: published February 27, 2019 | https://doi.org/10.1371/journal.ppat.1007593

Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells

Jasmin Akter, David S. Khoury, Rosemary Aogo, Lianne I. M. Lansink, Arya SheelaNair, Bryce S. Thomas, Pawat Laohamonthonkul, Clara P. S. Pernold, Matthew W. A. Dixon, Megan S. F. Soon, Lily G. Fogg, Jessica A. Engel, Trish Elliott, Ismail Sebina, Kylie R. James, Deborah Cromer, Miles P. Davenport, Ashraful Haque

PLOS Pathogens: published February 27, 2019 | https://doi.org/10.1371/journal.ppat.1007599

Single-cell characterization and quantification of translation-competent viral reservoirs in treated and untreated HIV infection

Marion Pardons, Amy E. Baxter, Marta Massanella, Amélie Pagliuzza, Rémi Fromentin, Caroline Dufour, Louise Leyre, Jean-Pierre Routy, Daniel E. Kaufmann, Nicolas Chomont

PLOS Pathogens: published February 27, 2019 | https://doi.org/10.1371/journal.ppat.1007619

NDRG1 facilitates the replication and persistence of Kaposi’s sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA

Fang Zhang, Deguang Liang, Xiaoxi Lin, Zhe Zou, Rui Sun, Xing Wang, Xiaozhen Liang, Kenneth M. Kaye, Ke Lan

PLOS Pathogens: published February 27, 2019 | https://doi.org/10.1371/journal.ppat.1007628

The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection

Rui Zhang, Monica Varela, Wies Vallentgoed, Gabriel Forn-Cuni, Michiel van der Vaart, Annemarie H. Meijer

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007329

High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2

Sujita Khanal, Denise A. Galloway

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007442

Colonization of the tsetse fly midgut with commensal Kosakonia cowanii Zambiae inhibits trypanosome infection establishment

Brian L. Weiss, Michele A. Maltz, Aurélien Vigneron, Yineng Wu, Katharine S. Walter, Michelle B. O’Neill, Jingwen Wang, Serap Aksoy

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007470

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Complete protection of the BALB/c and C57BL/6J mice against Ebola and Marburg virus lethal challenges by pan-filovirus T-cell epigraph vaccine

Md Niaz Rahim, Edmund G. Wee, Shihua He, Jonathan Audet, Kevin Tierney, Nathifa Moyo, Zara Hannoun, Alison Crook, Andrea Baines, Bette Korber, Xiangguo Qiu, Tomáš Hanke

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007564

Sensing of cell-associated HTLV by plasmacytoid dendritic cells is regulated by dense β-galactoside glycosylation

Sonia Assil, Nicolas Futsch, Elodie Décembre, Sandrine Alais, Antoine Gessain, François-Loïc Cosset, Renaud Mahieux, Marlène Dreux, Hélène Dutartre

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007589

Interleukin 21 collaborates with interferon-γ for the optimal expression of interferon-stimulated genes and enhances protection against enteric microbial infection

Shahram Solaymani-Mohammadi, Jay A. Berzofsky

PLOS Pathogens: published February 28, 2019 | https://doi.org/10.1371/journal.ppat.1007614

Correction: Bacillus anthracis Spore Surface Protein BclA Mediates Complement Factor H Binding to Spores and Promotes Spore Persistence

Yanyu Wang, Sarah A. Jenkins, Chunfang Gu, Ankita Shree, Margarita Martinez-Moczygemba, Jennifer Herold, Marina Botto, Rick A. Wetsel, Yi Xu

PLOS Pathogens: published February 8, 2019 | https://doi.org/10.1371/journal.ppat.1007579

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1. Bacillus anthracis Spore Surface Protein BclA Mediates Complement Factor H Binding to Spores and Promotes Spore Persistence

Correction: Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1

Romel D. Mackelprang, Michael J. Bamshad, Jessica X. Chong, Xuanlin Hou, Kati J. Buckingham, Kathryn Shively, Guy deBruyn, Nelly R. Mugo, James I. Mullins, M. Juliana McElrath, Jared M. Baeten, Connie Celum, Mary J. Emond, Jairam R. Lingappa, for the Partners in Prevention HSV/HIV Transmission Study and the Partners PrEP Study Teams

PLOS Pathogens: published February 11, 2019 | https://doi.org/10.1371/journal.ppat.1007588

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1. Whole genome sequencing of extreme phenotypes identifies variants in CD101 and UBE2V1 associated with increased risk of sexually acquired HIV-1

Correction: Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome

Agnieszka Szymula, Richard D. Palermo, Amr Bayoumy, Ian J. Groves, Mohammed Ba abdullah, Beth Holder, Robert E. White

PLOS Pathogens: published February 21, 2019 | https://doi.org/10.1371/journal.ppat.1007403

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1. Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome