Helminth infection–induced malignancy

Paul J. Brindley, Alex Loukas

PLOS Pathogens: published July 27, 2017 | https://doi.org/10.1371/journal.ppat.1006393

Revisiting the concept of a cytopathic viral infection

Nicholas S. Heaton

PLOS Pathogens: published July 20, 2017 | https://doi.org/10.1371/journal.ppat.1006409

Ash dieback epidemic in Europe: How can molecular technologies help?

J. Allan Downie

PLOS Pathogens: published July 20, 2017 | https://doi.org/10.1371/journal.ppat.1006381

An overview of genetic rust resistance: From broad to specific mechanisms

Sambasivam Periyannan, Ricky J. Milne, Melania Figueroa, Evans S. Lagudah, Peter N. Dodds

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006380

Developing transmission-blocking strategies for malaria control

Robert E. Sinden

PLOS Pathogens: published July 6, 2017 | https://doi.org/10.1371/journal.ppat.1006336

Prion strains in mammals: Different conformations leading to disease

Rodrigo Morales

PLOS Pathogens: published July 6, 2017 | https://doi.org/10.1371/journal.ppat.1006323

Toxoplasma gondii: Entry, association, and physiological influence on the central nervous system

Oscar A. Mendez, Anita A. Koshy

PLOS Pathogens: published July 20, 2017 | https://doi.org/10.1371/journal.ppat.1006351

What viruses can teach us about the human immune system

Michaela U. Gack

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006364

The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

James T. Earnest, Michael P. Hantak, Kun Li, Paul B. McCray Jr, Stanley Perlman, Tom Gallagher

PLOS Pathogens: published July 31, 2017 | https://doi.org/10.1371/journal.ppat.1006546

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

Yashaswini Kannan, Lewis J. Entwistle, Victoria S. Pelly, Jimena Perez-Lloret, Alan W. Walker, Steven C. Ley, Mark S. Wilson

PLOS Pathogens: published July 31, 2017 | https://doi.org/10.1371/journal.ppat.1006536

The role of co-opted ESCRT proteins and lipid factors in protection of tombusviral double-stranded RNA replication intermediate against reconstituted RNAi in yeast

Nikolay Kovalev, Jun-ichi Inaba, Zhenghe Li, Peter D. Nagy

PLOS Pathogens: published July 31, 2017 | https://doi.org/10.1371/journal.ppat.1006520

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

Gustavo H. Kijak, Eric Sanders-Buell, Agnes-Laurence Chenine, Michael A. Eller, Nilu Goonetilleke, Rasmi Thomas, Sivan Leviyang, Elizabeth A. Harbolick, Meera Bose, Phuc Pham, Celina Oropeza, Kultida Poltavee, Anne Marie O’Sullivan, Erik Billings, Melanie Merbah, Margaret C. Costanzo, Joanna A. Warren, Bonnie Slike, Hui Li, Kristina K. Peachman, Will Fischer, Feng Gao, Claudia Cicala, James Arthos, Leigh A. Eller, Robert J. O’Connell, Samuel Sinei, Lucas Maganga, Hannah Kibuuka, Sorachai Nitayaphan, Mangala Rao, Mary A. Marovich, Shelly J. Krebs, Morgane Rolland, Bette T. Korber, George M. Shaw, Nelson L. Michael, Merlin L. Robb, Sodsai Tovanabutra, Jerome H. Kim

PLOS Pathogens: published July 31, 2017 | https://doi.org/10.1371/journal.ppat.1006510

Related Articles

1. Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

HIV-1 infection depletes human CD34⁺CD38^- hematopoietic progenitor cells via pDC-dependent mechanisms

Guangming Li, Juanjuan Zhao, Liang Cheng, Qi Jiang, Sheng Kan, Enqiang Qin, Bo Tu, Xin Zhang, Liguo Zhang, Lishan Su, Zheng Zhang

PLOS Pathogens: published July 31, 2017 | https://doi.org/10.1371/journal.ppat.1006505

T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein

Camilla R. Fisher, Henry J. Sutton, Joe A. Kaczmarski, Hayley A. McNamara, Ben Clifton, Joshua Mitchell, Yeping Cai, Johanna N. Dups, Nicholas J. D'Arcy, Mandeep Singh, Aaron Chuah, Thomas S. Peat, Colin J. Jackson, Ian A. Cockburn

PLOS Pathogens: published July 31, 2017 | https://doi.org/10.1371/journal.ppat.1006469

Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells

Simone Haeberlein, Katja Obieglo, Arifa Ozir-Fazalalikhan, Mathilde A. M. Chayé, Henrike Veninga, Luciën E. P. M. van der Vlugt, Astrid Voskamp, Louis Boon, Joke M. M. den Haan, Lotte B. Westerhof, Ruud H. P. Wilbers, Arjen Schots, Gabriele Schramm, Cornelis H. Hokke, Hermelijn H. Smits

PLOS Pathogens: published July 28, 2017 | https://doi.org/10.1371/journal.ppat.1006539

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

Julien Pompon, Menchie Manuel, Geok Kee Ng, Benjamin Wong, Chao Shan, Gayathri Manokaran, Ruben Soto-Acosta, Shelton S. Bradrick, Eng Eong Ooi, Dorothée Missé, Pei-Yong Shi, Mariano A. Garcia-Blanco

PLOS Pathogens: published July 28, 2017 | https://doi.org/10.1371/journal.ppat.1006535

Bacterial effector NleL promotes enterohemorrhagic E. coli-induced attaching and effacing lesions by ubiquitylating and inactivating JNK

Xiangpeng Sheng, Qing You, Hongnian Zhu, ZeNan Chang, Qingrun Li, Haifeng Wang, Chen Wang, Hongyan Wang, Lijian Hui, Chongtao Du, Xiaoduo Xie, Rong Zeng, Anning Lin, Dongfang Shi, Kangcheng Ruan, Jinghua Yan, George Fu Gao, Feng Shao, Ronggui Hu

PLOS Pathogens: published July 28, 2017 | https://doi.org/10.1371/journal.ppat.1006534

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth

Lisa N. Glass, Ganduri Swapna, Sivagami Sundaram Chavadi, JoAnn M. Tufariello, Kaixia Mi, Joshua E. Drumm, TuKiet T. Lam, Guofeng Zhu, Chenyang Zhan, Catherine Vilchéze, Jesus Arcos, Yong Chen, Lijun Bi, Simren Mehta, Steven A. Porcelli, Steve C. Almo, Syun-Ru Yeh, William R. Jacobs Jr., Jordi B. Torrelles, John Chan

PLOS Pathogens: published July 28, 2017 | https://doi.org/10.1371/journal.ppat.1006515

Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase

Xi-Juan Liu, Bo Yang, Sheng-Nan Huang, Cong-Cong Wu, Xiao-Jun Li, Shuang Cheng, Xuan Jiang, Fei Hu, Ying-Zi Ming, Michael Nevels, William J. Britt, Simon Rayner, Qiyi Tang, Wen-Bo Zeng, Fei Zhao, Min-Hua Luo

PLOS Pathogens: published July 27, 2017 | https://doi.org/10.1371/journal.ppat.1006542

Cross-modulation of pathogen-specific pathways enhances malnutrition during enteric co-infection with Giardia lamblia and enteroaggregative Escherichia coli

Luther A. Bartelt, David T. Bolick, Jordi Mayneris-Perxachs, Glynis L. Kolling, Gregory L. Medlock, Edna I. Zaenker, Jeffery Donowitz, Rose Viguna Thomas-Beckett, Allison Rogala, Ian M. Carroll, Steven M. Singer, Jason Papin, Jonathan R. Swann, Richard L. Guerrant

PLOS Pathogens: published July 27, 2017 | https://doi.org/10.1371/journal.ppat.1006471

Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques

Timothy Carroll, Ming Lo, Marion Lanteri, Joseph Dutra, Katie Zarbock, Paola Silveira, Tracy Rourke, Zhong-min Ma, Linda Fritts, Shelby O’Connor, Michael Busch, Christopher J. Miller

PLOS Pathogens: published July 26, 2017 | https://doi.org/10.1371/journal.ppat.1006537

Salmonella enterica serovar-specific transcriptional reprogramming of infected cells

Sebastian Hannemann, Jorge E. Galán

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006532

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface

Elise S. Hovingh, Bryan van den Broek, Betsy Kuipers, Elena Pinelli, Suzan H. M. Rooijakkers, Ilse Jongerius

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006531

Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis

Bartłomiej Salamaga, Tomasz K. Prajsnar, Ana Jareño-Martinez, Joost Willemse, Martin A. Bewley, Françoise Chau, Tassadit Ben Belkacem, Annemarie H. Meijer, David H. Dockrell, Stephen A. Renshaw, Stéphane Mesnage

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006526

Abundance and co-occurrence of extracellular capsules increase environmental breadth: Implications for the emergence of pathogens

Olaya Rendueles, Marc Garcia-Garcerà, Bertrand Néron, Marie Touchon, Eduardo P. C. Rocha

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006525

Hijacking of the O-GlcNAcZYME complex by the HTLV-1 Tax oncoprotein facilitates viral transcription

Damien Groussaud, Mostafa Khair, Armelle I. Tollenaere, Laetitia Waast, Mei-Shiue Kuo, Marianne Mangeney, Christophe Martella, Yann Fardini, Solène Coste, Mouloud Souidi, Laurence Benit, Claudine Pique, Tarik Issad

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006518

Tpc1 is an important Zn(II)₂Cys₆ transcriptional regulator required for polarized growth and virulence in the rice blast fungus

Rita Galhano, Adriana Illana, Lauren S. Ryder, Julio Rodríguez-Romero, Marie Demuez, Muhammad Badaruddin, Ana Lilia Martinez-Rocha, Darren M. Soanes, David J. Studholme, Nicholas J. Talbot, Ane Sesma

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006516

An essential EBV latent antigen 3C binds Bcl6 for targeted degradation and cell proliferation

Yonggang Pei, Shuvomoy Banerjee, Hem Chandra Jha, Zhiguo Sun, Erle S. Robertson

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006500

Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

Jennifer A. Stortz, Tiago D. Serafim, Sam Alsford, Jonathan Wilkes, Fernando Fernandez-Cortes, Graham Hamilton, Emma Briggs, Leandro Lemgruber, David Horn, Jeremy C. Mottram, Richard McCulloch

PLOS Pathogens: published July 24, 2017 | https://doi.org/10.1371/journal.ppat.1006477

Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa

Dan Wang, Weizhong Chen, Shanqing Huang, Yafeng He, Xichun Liu, Qingyuan Hu, Tianbiao Wei, Hong Sang, Jianhua Gan, Hao Chen

PLOS Pathogens: published July 21, 2017 | https://doi.org/10.1371/journal.ppat.1006533

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques

Mauricio A. Martins, Young C. Shin, Lucas Gonzalez-Nieto, Aline Domingues, Martin J. Gutman, Helen S. Maxwell, Iris Castro, Diogo M. Magnani, Michael Ricciardi, Nuria Pedreño-Lopez, Varian Bailey, Dillon Betancourt, John D. Altman, Matthias Pauthner, Dennis R. Burton, Benjamin von Bredow, David T. Evans, Maoli Yuan, Christopher L. Parks, Keisuke Ejima, David B. Allison, Eva Rakasz, Glen N. Barber, Saverio Capuano III, Jeffrey D. Lifson, Ronald C. Desrosiers, David I. Watkins

PLOS Pathogens: published July 21, 2017 | https://doi.org/10.1371/journal.ppat.1006529

CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo

Nadia T. Sebastian, Thomas D. Zaikos, Valeri Terry, Frances Taschuk, Lucy A. McNamara, Adewunmi Onafuwa-Nuga, Ryan Yucha, Robert A. J. Signer, James Riddell IV, Dale Bixby, Norman Markowitz, Sean J. Morrison, Kathleen L. Collins

PLOS Pathogens: published July 21, 2017 | https://doi.org/10.1371/journal.ppat.1006509

Related Articles

1. Correction: CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo

LMP1-mediated glycolysis induces myeloid-derived suppressor cell expansion in nasopharyngeal carcinoma

Ting-Ting Cai, Shu-Biao Ye, Yi-Na Liu, Jia He, Qiu-Yan Chen, Hai-Qiang Mai, Chuan-Xia Zhang, Jun Cui, Xiao-Shi Zhang, Pierre Busson, Yi-Xin Zeng, Jiang Li

PLOS Pathogens: published July 21, 2017 | https://doi.org/10.1371/journal.ppat.1006503

Cucumber mosaic virus coat protein modulates the accumulation of 2b protein and antiviral silencing that causes symptom recovery in planta

Xiao-Peng Zhang, De-Shui Liu, Teng Yan, Xiao-Dong Fang, Kai Dong, Jin Xu, Ying Wang, Jia-Lin Yu, Xian-Bing Wang

PLOS Pathogens: published July 20, 2017 | https://doi.org/10.1371/journal.ppat.1006522

Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation

Alexander Zhyvoloup, Anat Melamed, Ian Anderson, Delphine Planas, Chen-Hsuin Lee, Janos Kriston-Vizi, Robin Ketteler, Andy Merritt, Jean-Pierre Routy, Petronela Ancuta, Charles R. M. Bangham, Ariberto Fassati

PLOS Pathogens: published July 20, 2017 | https://doi.org/10.1371/journal.ppat.1006460

Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation

Nadezhda Tikhmyanova, Steve Tutton, Kayla A. Martin, Fang Lu, Andrew V. Kossenkov, Nicholas Paparoidamis, Shannon Kenney, Joseph M. Salvino, Paul M. Lieberman

PLOS Pathogens: published July 17, 2017 | https://doi.org/10.1371/journal.ppat.1006517

Helicobacter pylori modulates host cell responses by CagT4SS-dependent translocation of an intermediate metabolite of LPS inner core heptose biosynthesis

Saskia C. Stein, Eugenia Faber, Simon H. Bats, Tatiana Murillo, Yvonne Speidel, Nina Coombs, Christine Josenhans

PLOS Pathogens: published July 17, 2017 | https://doi.org/10.1371/journal.ppat.1006514

microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus

Sunantha Sethuraman, Lauren Appleby Gay, Vaibhav Jain, Irina Haecker, Rolf Renne

PLOS Pathogens: published July 17, 2017 | https://doi.org/10.1371/journal.ppat.1006508

The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer

Sampriti Mukherjee, Dina Moustafa, Chari D. Smith, Joanna B. Goldberg, Bonnie L. Bassler

PLOS Pathogens: published July 17, 2017 | https://doi.org/10.1371/journal.ppat.1006504

Host genetics play a critical role in controlling CD8 T cell function and lethal immunopathology during chronic viral infection

Allison F. Christiaansen, Megan E. Schmidt, Stacey M. Hartwig, Steven M. Varga

PLOS Pathogens: published July 17, 2017 | https://doi.org/10.1371/journal.ppat.1006498

KIR3DL01 upregulation on gut natural killer cells in response to SIV infection of KIR- and MHC class I-defined rhesus macaques

Moritz Ries, Matthew R. Reynolds, Ksenia Bashkueva, Kristin Crosno, Saverio Capuano III, Trent M. Prall, Roger Wiseman, David H. O’Connor, Eva G. Rakasz, Hajime Uno, Jeffrey D. Lifson, David T. Evans

PLOS Pathogens: published July 14, 2017 | https://doi.org/10.1371/journal.ppat.1006506

Negative modulation of suppressive HIV-specific regulatory T cells by IL-2 adjuvanted therapeutic vaccine

Vedran Brezar, Lylia Hani, Mathieu Surenaud, Audrey Hubert, Christine Lacabaratz, Jean-Daniel Lelièvre, Yves Levy, Nabila Seddiki

PLOS Pathogens: published July 14, 2017 | https://doi.org/10.1371/journal.ppat.1006489

The transcriptional regulator SsrB is involved in a molecular switch controlling virulence lifestyles of Salmonella

Deyanira Pérez-Morales, María M. Banda, N. Y Elizabeth Chau, Heladia Salgado, Irma Martínez-Flores, J. Antonio Ibarra, Bushra Ilyas, Brian K. Coombes, Víctor H. Bustamante

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006497

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense

Philip O. Scumpia, Giovanni A. Botten, Joshua S. Norman, Kindra M. Kelly-Scumpia, Roberto Spreafico, Amber R. Ruccia, Prabhat K. Purbey, Brandon J. Thomas, Robert L. Modlin, Stephen T. Smale

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006496

A virulence-associated filamentous bacteriophage of Neisseria meningitidis increases host-cell colonisation

Emmanuelle Bille, Julie Meyer, Anne Jamet, Daniel Euphrasie, Jean-Philippe Barnier, Terry Brissac, Anna Larsen, Philippe Pelissier, Xavier Nassif

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006495

Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores

Travis J. Kochan, Madeline J. Somers, Alyssa M. Kaiser, Michelle S. Shoshiev, Ada K. Hagan, Jessica L. Hastie, Nicole P. Giordano, Ashley D. Smith, Alyxandria M. Schubert, Paul E. Carlson Jr, Philip C. Hanna

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006443

Related Articles

1. Correction: Intestinal calcium and bile salts facilitate germination of Clostridium difficile spores

Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development

Ritesh Kumar, Jennifer L. Herold, Deborah Schady, Jennifer Davis, Scott Kopetz, Margarita Martinez-Moczygemba, Barbara E. Murray, Fang Han, Yu Li, Evelyn Callaway, Robert S. Chapkin, Wan-Mohaiza Dashwood, Roderick H. Dashwood, Tia Berry, Chris Mackenzie, Yi Xu

PLOS Pathogens: published July 13, 2017 | https://doi.org/10.1371/journal.ppat.1006440

Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

Fei Wang, Xinhe Wang, Christina D. Orrú, Bradley R. Groveman, Krystyna Surewicz, Romany Abskharon, Morikazu Imamura, Takashi Yokoyama, Yong-Sun Kim, Kayla J. Vander Stel, Kumar Sinniah, Suzette A. Priola, Witold K. Surewicz, Byron Caughey, Jiyan Ma

PLOS Pathogens: published July 12, 2017 | https://doi.org/10.1371/journal.ppat.1006491

Rapid identification of genes controlling virulence and immunity in malaria parasites

Hussein M. Abkallo, Axel Martinelli, Megumi Inoue, Abhinay Ramaprasad, Phonepadith Xangsayarath, Jesse Gitaka, Jianxia Tang, Kazuhide Yahata, Augustin Zoungrana, Hayato Mitaka, Arita Acharjee, Partha P. Datta, Paul Hunt, Richard Carter, Osamu Kaneko, Ville Mustonen, Christopher J. R. Illingworth, Arnab Pain, Richard Culleton

PLOS Pathogens: published July 12, 2017 | https://doi.org/10.1371/journal.ppat.1006447

T follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection

Maria Marta Figueiredo, Pedro Augusto Carvalho Costa, Suelen Queiroz Diniz, Priscilla Miranda Henriques, Flora Satiko Kano, Mauro Sugiro Tada, Dhelio Batista Pereira, Irene Silva Soares, Olindo Assis Martins-Filho, Dragana Jankovic, Ricardo Tostes Gazzinelli, Lis Ribeiro do Valle Antonelli

PLOS Pathogens: published July 10, 2017 | https://doi.org/10.1371/journal.ppat.1006484

The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes

Christine R. Collins, Fiona Hackett, Jonathan Atid, Michele Ser Ying Tan, Michael J. Blackman

PLOS Pathogens: published July 6, 2017 | https://doi.org/10.1371/journal.ppat.1006453

Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes

Shiou-Ling Lu, Tsuyoshi Kawabata, Yi-Lin Cheng, Hiroko Omori, Maho Hamasaki, Tatsuya Kusaba, Ryo Iwamoto, Hirokazu Arimoto, Takeshi Noda, Yee-Shin Lin, Tamotsu Yoshimori

PLOS Pathogens: published July 6, 2017 | https://doi.org/10.1371/journal.ppat.1006444

Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis

Hiroaki Takeuchi, Hideki Saito, Takeshi Noda, Tadashi Miyamoto, Tomokazu Yoshinaga, Kazutaka Terahara, Hiroshi Ishii, Yasuko Tsunetsugu-Yokota, Shoji Yamaoka

PLOS Pathogens: published July 6, 2017 | https://doi.org/10.1371/journal.ppat.1006441

Generality of toxins in defensive symbiosis: Ribosome-inactivating proteins and defense against parasitic wasps in Drosophila

Matthew J. Ballinger, Steve J. Perlman

PLOS Pathogens: published July 6, 2017 | https://doi.org/10.1371/journal.ppat.1006431

KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation

Roxanne C. Strahan, Maria McDowell-Sargent, Timsy Uppal, Pravinkumar Purushothaman, Subhash C. Verma

PLOS Pathogens: published July 5, 2017 | https://doi.org/10.1371/journal.ppat.1006482

Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration

E. Fabian Cardozo, Adriana Andrade, John W. Mellors, Daniel R. Kuritzkes, Alan S. Perelson, Ruy M. Ribeiro

PLOS Pathogens: published July 5, 2017 | https://doi.org/10.1371/journal.ppat.1006478

Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum

Tzu-Hsuan Chang, Juin-Hua Huang, Hsiu-Chao Lin, Wen-Yu Chen, Yu-Hsiang Lee, Li-Chung Hsu, Mihai G. Netea, Jenny P.-Y. Ting, Betty A. Wu-Hsieh

PLOS Pathogens: published July 3, 2017 | https://doi.org/10.1371/journal.ppat.1006485

Checkpoints of apicomplexan cell division identified in Toxoplasma gondii

Carmelo A. Alvarez, Elena S. Suvorova

PLOS Pathogens: published July 3, 2017 | https://doi.org/10.1371/journal.ppat.1006483

Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway

Yael Litvak, Shir Sharon, Meirav Hyams, Li Zhang, Simi Kobi, Naama Katsowich, Shira Dishon, Gabriel Nussbaum, Na Dong, Feng Shao, Ilan Rosenshine

PLOS Pathogens: published July 3, 2017 | https://doi.org/10.1371/journal.ppat.1006472

Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission

Sidney M. Bell, Trevor Bedford

PLOS Pathogens: published July 3, 2017 | https://doi.org/10.1371/journal.ppat.1006466

TNF signalling drives expansion of bone marrow CD4⁺ T cells responsible for HSC exhaustion in experimental visceral leishmaniasis

Ana Isabel Pinto, Najmeeyah Brown, Olivier Preham, Johannes S. P. Doehl, Helen Ashwin, Paul M. Kaye

PLOS Pathogens: published July 3, 2017 | https://doi.org/10.1371/journal.ppat.1006465