The Problem of Auto-Correlation in Parasitology

Laura C. Pollitt, Sarah E. Reece, Nicole Mideo, Daniel H. Nussey, Nick Colegrave

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002590

The Accessory Genome as a Cradle for Adaptive Evolution in Pathogens

Daniel Croll, Bruce A. McDonald

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002608

The Role of Mast Cells in the Defence against Pathogens

Mirjam Urb, Donald C. Sheppard

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002619

The Arbuscular Mycorrhizal Symbiosis: Origin and Evolution of a Beneficial Plant Infection

Nicolas Corradi, Paola Bonfante

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002600

The Role of Cofactors in Prion Propagation and Infectivity

Jiyan Ma

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002589

Fungal Biofilms

Saranna Fanning, Aaron P. Mitchell

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002585

Systematic Review of Mucosal Immunity Induced by Oral and Inactivated Poliovirus Vaccines against Virus Shedding following Oral Poliovirus Challenge

Thomas R. Hird, Nicholas C. Grassly

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002599

Ross, Macdonald, and a Theory for the Dynamics and Control of Mosquito-Transmitted Pathogens

David L. Smith, Katherine E. Battle, Simon I. Hay, Christopher M. Barker, Thomas W. Scott, F. Ellis McKenzie

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002588

IL-17RA Signaling Reduces Inflammation and Mortality during Trypanosoma cruzi Infection by Recruiting Suppressive IL-10-Producing Neutrophils

Jimena Tosello Boari, María Carolina Amezcua Vesely, Daniela Andrea Bermejo, Maria Cecilia Ramello, Carolina Lucía Montes, Hugo Cejas, Adriana Gruppi, Eva Virginia Acosta Rodríguez

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002658

A Novel Small Molecule Inhibitor of Influenza A Viruses that Targets Polymerase Function and Indirectly Induces Interferon

Mila Brum Ortigoza, Oliver Dibben, Jad Maamary, Luis Martinez-Gil, Victor H. Leyva-Grado, Pablo Abreu Jr., Juan Ayllon, Peter Palese, Megan L. Shaw

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002668

Macrophage Activation Associated with Chronic Murine Cytomegalovirus Infection Results in More Severe Experimental Choroidal Neovascularization

Scott W. Cousins, Diego G. Espinosa-Heidmann, Daniel M. Miller, Simone Pereira-Simon, Eleut P. Hernandez, Hsin Chien, Courtney Meier-Jewett, Richard D. Dix

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002671

A Role for SKN-1/Nrf in Pathogen Resistance and Immunosenescence in Caenorhabditis elegans

Diána Papp, Péter Csermely, Csaba Sőti

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002673

Reversing the Resistance Phenotype of the Biomphalaria glabrata Snail Host Schistosoma mansoni Infection by Temperature Modulation

Wannaporn Ittiprasert, Matty Knight

PLOS Pathogens: published April 26, 2012 | https://doi.org/10.1371/journal.ppat.1002677

Loss of Anti-Viral Immunity by Infection with a Virus Encoding a Cross-Reactive Pathogenic Epitope

Alex T. Chen, Markus Cornberg, Stephanie Gras, Carole Guillonneau, Jamie Rossjohn, Andrew Trees, Sebastien Emonet, Juan C. de la Torre, Raymond M. Welsh, Liisa K. Selin

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002633

CD8⁺ T-Cells Expressing Interferon Gamma or Perforin Play Antagonistic Roles in Heart Injury in Experimental Trypanosoma Cruzi-Elicited Cardiomyopathy

Jaline Coutinho Silverio, Isabela Resende Pereira, Márcio da Costa Cipitelli, Nathália Ferreira Vinagre, Maurício Martins Rodrigues, Ricardo Tostes Gazzinelli, Joseli Lannes-Vieira

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002645

Modelling the Evolutionary Dynamics of Viruses within Their Hosts: A Case Study Using High-Throughput Sequencing

Frédéric Fabre, Josselin Montarry, Jérôme Coville, Rachid Senoussi, Vincent Simon, Benoît Moury

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002654

CLEC5A Regulates Japanese Encephalitis Virus-Induced Neuroinflammation and Lethality

Szu-Ting Chen, Ren-Shyan Liu, Ming-Fang Wu, Yi-Ling Lin, Se-Yi Chen, David Tat-Wei Tan, Teh-Ying Chou, I-Shuen Tsai, Lei Li, Shie-Liang Hsieh

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002655

Entry of Human Papillomavirus Type 16 by Actin-Dependent, Clathrin- and Lipid Raft-Independent Endocytosis

Mario Schelhaas, Bhavin Shah, Michael Holzer, Peter Blattmann, Lena Kühling, Patricia M. Day, John T. Schiller, Ari Helenius

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002657

Proteolytic Processing of Nlrp1b Is Required for Inflammasome Activity

Bradley C. Frew, Vineet R. Joag, Jeremy Mogridge

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002659

T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice

Daniel R. Neill, Vitor E. Fernandes, Laura Wisby, Andrew R. Haynes, Daniela M. Ferreira, Ameera Laher, Natalie Strickland, Stephen B. Gordon, Paul Denny, Aras Kadioglu, Peter W. Andrew

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002660

AMP-Activated Kinase Restricts Rift Valley Fever Virus Infection by Inhibiting Fatty Acid Synthesis

Theresa S. Moser, Daniel Schieffer, Sara Cherry

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002661

Epstein-Barr Virus LMP2A Reduces Hyperactivation Induced by LMP1 to Restore Normal B Cell Phenotype in Transgenic Mice

Alexandra C. Vrazo, Maria Chauchard, Nancy Raab-Traub, Richard Longnecker

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002662

A GATA Transcription Factor Recruits Hda1 in Response to Reduced Tor1 Signaling to Establish a Hyphal Chromatin State in Candida albicans

Yang Lu, Chang Su, Haoping Liu

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002663

Induction of Strain-Transcending Antibodies Against Group A PfEMP1 Surface Antigens from Virulent Malaria Parasites

Ashfaq Ghumra, Jean-Philippe Semblat, Ricardo Ataide, Carolyne Kifude, Yvonne Adams, Antoine Claessens, Damian N. Anong, Peter C. Bull, Clare Fennell, Monica Arman, Alfred Amambua-Ngwa, Michael Walther, David J. Conway, Lalla Kassambara, Ogobara K. Doumbo, Ahmed Raza, J. Alexandra Rowe

PLOS Pathogens: published April 19, 2012 | https://doi.org/10.1371/journal.ppat.1002665

Structural Basis for Type VI Secretion Effector Recognition by a Cognate Immunity Protein

Mo Li, Isolde Le Trong, Mike A. Carl, Eric T. Larson, Seemay Chou, Justin A. De Leon, Simon L. Dove, Ronald E. Stenkamp, Joseph D. Mougous

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002613

Necrotrophism Is a Quorum-Sensing-Regulated Lifestyle in Bacillus thuringiensis

Thomas Dubois, Karoline Faegri, Stéphane Perchat, Christelle Lemy, Christophe Buisson, Christina Nielsen-LeRoux, Michel Gohar, Philippe Jacques, Nalini Ramarao, Anne-Brit Kolstø, Didier Lereclus

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002629

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Treatment with IL-7 Prevents the Decline of Circulating CD4⁺ T Cells during the Acute Phase of SIV Infection in Rhesus Macaques

Lia Vassena, Huiyi Miao, Raffaello Cimbro, Mauro S. Malnati, Giulia Cassina, Michael A. Proschan, Vanessa M. Hirsch, Bernard A. Lafont, Michel Morre, Anthony S. Fauci, Paolo Lusso

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002636

Interaction of the Trans-Frame Potyvirus Protein P3N-PIPO with Host Protein PCaP1 Facilitates Potyvirus Movement

Paramasivan Vijayapalani, Masayoshi Maeshima, Nahoko Nagasaki-Takekuchi, W. Allen Miller

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002639

TLR4 and NKT Cell Synergy in Immunotherapy against Visceral Leishmaniasis

Subir Karmakar, Siddhartha Kumar Bhaumik, Joydeep Paul, Tripti De

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002646

Intraspecies Variation in the Emergence of Hyperinfectious Bacterial Strains in Nature

Douglas M. Heithoff, William R. Shimp, John K. House, Yi Xie, Bart C. Weimer, Robert L. Sinsheimer, Michael J. Mahan

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002647

The Transcription Factor AmrZ Utilizes Multiple DNA Binding Modes to Recognize Activator and Repressor Sequences of Pseudomonas aeruginosa Virulence Genes

Edward E. Pryor Jr., Elizabeth A. Waligora, Binjie Xu, Sheri Dellos-Nolan, Daniel J. Wozniak, Thomas Hollis

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002648

In Vivo Suppression of HIV by Antigen Specific T Cells Derived from Engineered Hematopoietic Stem Cells

Scott G. Kitchen, Bernard R. Levin, Gregory Bristol, Valerie Rezek, Sohn Kim, Christian Aguilera-Sandoval, Arumugam Balamurugan, Otto O. Yang, Jerome A. Zack

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002649

Neutralization Serotyping of BK Polyomavirus Infection in Kidney Transplant Recipients

Diana V. Pastrana, Daniel C. Brennan, Nicolas Çuburu, Gregory A. Storch, Raphael P. Viscidi, Parmjeet S. Randhawa, Christopher B. Buck

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002650

Human Monoclonal Antibodies to a Novel Cluster of Conformational Epitopes on HCV E2 with Resistance to Neutralization Escape in a Genotype 2a Isolate

Zhen-yong Keck, Jinming Xia, Yong Wang, Wenyan Wang, Thomas Krey, Jannick Prentoe, Thomas Carlsen, Angela Ying-Jian Li, Arvind H. Patel, Stanley M. Lemon, Jens Bukh, Felix A. Rey, Steven K. H. Foung

PLOS Pathogens: published April 12, 2012 | https://doi.org/10.1371/journal.ppat.1002653

Calcium Influx Rescues Adenylate Cyclase-Hemolysin from Rapid Cell Membrane Removal and Enables Phagocyte Permeabilization by Toxin Pores

Radovan Fiser, Jiri Masin, Ladislav Bumba, Eva Pospisilova, Catherine Fayolle, Marek Basler, Lenka Sadilkova, Irena Adkins, Jana Kamanova, Jan Cerny, Ivo Konopasek, Radim Osicka, Claude Leclerc, Peter Sebo

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002580

CEACAM1 Negatively Regulates IL-1β Production in LPS Activated Neutrophils by Recruiting SHP-1 to a SYK-TLR4-CEACAM1 Complex

Rongze Lu, Hao Pan, John E. Shively

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002597

Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway

Wook-Bin Lee, Ji-Seon Kang, Ji-Jing Yan, Myeong Sup Lee, Bo-Young Jeon, Sang-Nae Cho, Young-Joon Kim

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002614

An “Escape Clock” for Estimating the Turnover of SIV DNA in Resting CD4+ T Cells

Jeanette Reece, Janka Petravic, Mehala Balamurali, Liyen Loh, Shayarana Gooneratne, Rob De Rose, Stephen J. Kent, Miles P. Davenport

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002615

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Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

Iwona Bucior, Julia F. Pielage, Joanne N. Engel

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002616

Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation

Xianfang Wu, Jason M. Robotham, Emily Lee, Stephen Dalton, Norman M. Kneteman, David M. Gilbert, Hengli Tang

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002617

Modeling of the N-Glycosylated Transferrin Receptor Suggests How Transferrin Binding Can Occur within the Surface Coat of Trypanosoma brucei

Angela Mehlert, Mark R. Wormald, Michael A. J. Ferguson

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002618

Regulation of Mycobacterium tuberculosis-Dependent HIV-1 Transcription Reveals a New Role for NFAT5 in the Toll-Like Receptor Pathway

Shahin Ranjbar, Luke D. Jasenosky, Nancy Chow, Anne E. Goldfeld

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002620

Human Nasal Challenge with Streptococcus pneumoniae Is Immunising in the Absence of Carriage

Adam K. A. Wright, Daniela M. Ferreira, Jenna F. Gritzfeld, Angela D. Wright, Kathryn Armitage, Kondwani C. Jambo, Emily Bate, Sherouk El Batrawy, Andrea Collins, Stephen B. Gordon

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002622

The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm

Jin Xiao, Marlise I. Klein, Megan L. Falsetta, Bingwen Lu, Claire M. Delahunty, John R. Yates III, Arne Heydorn, Hyun Koo

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002623

Group A Streptococcus Secreted Esterase Hydrolyzes Platelet-Activating Factor to Impede Neutrophil Recruitment and Facilitate Innate Immune Evasion

Mengyao Liu, Hui Zhu, Jinquan Li, Cristiana C. Garcia, Wenchao Feng, Liliya N. Kirpotina, Jonathan Hilmer, Luciana P. Tavares, Arthur W. Layton, Mark T. Quinn, Brian Bothner, Mauro M. Teixeira, Benfang Lei

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002624

β-Microseminoprotein Endows Post Coital Seminal Plasma with Potent Candidacidal Activity by a Calcium- and pH-Dependent Mechanism

Anneli M. L. Edström Hägerwall, Victoria Rydengård, Per Fernlund, Matthias Mörgelin, Maria Baumgarten, Alexander M. Cole, Martin Malmsten, Birthe B. Kragelund, Ole E. Sørensen

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002625

Methicillin Resistance Alters the Biofilm Phenotype and Attenuates Virulence in Staphylococcus aureus Device-Associated Infections

Clarissa Pozzi, Elaine M. Waters, Justine K. Rudkin, Carolyn R. Schaeffer, Amanda J. Lohan, Pin Tong, Brendan J. Loftus, Gerald B. Pier, Paul D. Fey, Ruth C. Massey, James P. O'Gara

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002626

Small-Molecule Inhibitors of Dengue-Virus Entry

Aaron G. Schmidt, Kyungae Lee, Priscilla L. Yang, Stephen C. Harrison

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002627

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Virion Assembly Factories in the Nucleus of Polyomavirus-Infected Cells

Kimberly D. Erickson, Cedric Bouchet-Marquis, Katie Heiser, Eva Szomolanyi-Tsuda, Rabinarayan Mishra, Benjamin Lamothe, Andreas Hoenger, Robert L. Garcea

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002630

Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies

Irene A. Abela, Livia Berlinger, Merle Schanz, Lucy Reynell, Huldrych F. Günthard, Peter Rusert, Alexandra Trkola

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002634

Leishmania Induces Survival, Proliferation and Elevated Cellular dNTP Levels in Human Monocytes Promoting Acceleration of HIV Co-Infection

David J. Mock, Joseph A. Hollenbaugh, Waaqo Daddacha, Michael G. Overstreet, Chris A. Lazarski, Deborah J. Fowell, Baek Kim

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002635

Structural Basis of Cytotoxicity Mediated by the Type III Secretion Toxin ExoU from Pseudomonas aeruginosa

Claire Gendrin, Carlos Contreras-Martel, Stéphanie Bouillot, Sylvie Elsen, David Lemaire, Dimitrios A. Skoufias, Philippe Huber, Ina Attree, Andréa Dessen

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002637

Airborne Signals from a Wounded Leaf Facilitate Viral Spreading and Induce Antibacterial Resistance in Neighboring Plants

Yuri L. Dorokhov, Tatiana V. Komarova, Igor V. Petrunia, Olga Y. Frolova, Denis V. Pozdyshev, Yuri Y. Gleba

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002640

Matrix Metalloprotease 9 Mediates Neutrophil Migration into the Airways in Response to Influenza Virus-Induced Toll-Like Receptor Signaling

Linda M. Bradley, Mia F. Douglass, Dhrubamitra Chatterjee, Shizuo Akira, Bas J. G. Baaten

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002641

2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase

Hongping Dong, David C. Chang, Maggie Ho Chia Hua, Siew Pheng Lim, Yok Hian Chionh, Fabian Hia, Yie Hou Lee, Petra Kukkaro, Shee-Mei Lok, Peter C. Dedon, Pei-Yong Shi

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002642

Sequential Delivery of Host-Induced Virulence Effectors by Appressoria and Intracellular Hyphae of the Phytopathogen Colletotrichum higginsianum

Jochen Kleemann, Linda J. Rincon-Rivera, Hiroyuki Takahara, Ulla Neumann, Emiel Ver Loren van Themaat, H. Charlotte van der Does, Stéphane Hacquard, Kurt Stüber, Isa Will, Wolfgang Schmalenbach, Elmon Schmelzer, Richard J. O'Connell

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002643

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The Baculovirus Uses a Captured Host Phosphatase to Induce Enhanced Locomotory Activity in Host Caterpillars

Susumu Katsuma, Yasue Koyano, WonKyung Kang, Ryuhei Kokusho, Shizuo George Kamita, Toru Shimada

PLOS Pathogens: published April 5, 2012 | https://doi.org/10.1371/journal.ppat.1002644