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Table of Contents

March 2008

Cover

Arginase-1 and alpha smooth muscle actin expression colocalized in CAT2-/- granulomas
Issue Image

Liver sections from C57BL/6 CAT2-/- mice infected with S. mansoni for 10 wk were stained anti-F4/80-Alexa 488 (green), anti-Arg1-Alexa 647(red), and anti-Alpha Smooth Muscle Actin-Texas Red (blue). Individual 20x images were combined to provide this composite image (see Thompson et al., e1000023).

Image Credit: Image generated by John Pesce.

Review

The Lentiviral Integrase Binding Protein LEDGF/p75 and HIV-1 Replication

Alan Engelman, Peter Cherepanov

PLOS Pathogens: published March 28, 2008 | https://doi.org/10.1371/journal.ppat.1000046

Research Articles

Methylated DNA Recognition during the Reversal of Epigenetic Silencing Is Regulated by Cysteine and Serine Residues in the Epstein-Barr Virus Lytic Switch Protein

Questa H. Karlsson, Celine Schelcher, Elizabeth Verrall, Carlo Petosa, Alison J. Sinclair

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000005

Plasmodium-Induced Inflammation by Uric Acid

Jamie M. Orengo, James E. Evans, Esther Bettiol, Aleksandra Leliwa-Sytek, Karen Day, Ana Rodriguez

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000013

Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors

B. Josh Lane, Charla Mutchler, Souhaila Al Khodor, Scott S. Grieshaber, Rey A. Carabeo

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000014

Real-Time Visualization of HIV-1 GAG Trafficking in Infected Macrophages

Karine Gousset, Sherimay D. Ablan, Lori V. Coren, Akira Ono, Ferri Soheilian, Kunio Nagashima, David E. Ott, Eric O. Freed

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000015

A Virus-Encoded Cell–Cell Fusion Machine Dependent on Surrogate Adhesins

Jayme Salsman, Deniz Top, Christopher Barry, Roy Duncan

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000016

IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

Caroline Sommereyns, Sophie Paul, Peter Staeheli, Thomas Michiels

PLOS Pathogens: published March 14, 2008 | https://doi.org/10.1371/journal.ppat.1000017

A New Family of Lysozyme Inhibitors Contributing to Lysozyme Tolerance in Gram-Negative Bacteria

Lien Callewaert, Abram Aertsen, Daphne Deckers, Kristof G. A. Vanoirbeek, Lise Vanderkelen, Joris M. Van Herreweghe, Barbara Masschalck, Dorothy Nakimbugwe, Johan Robben, Chris W. Michiels

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000019

The Effect of Immune Selection on the Structure of the Meningococcal Opa Protein Repertoire

Martin J. Callaghan, Caroline O. Buckee, Keith A. Jolley, Paula Kriz, Martin C. J. Maiden, Sunetra Gupta

PLOS Pathogens: published March 14, 2008 | https://doi.org/10.1371/journal.ppat.1000020

RNA Interference Screen Identifies Abl Kinase and PDGFR Signaling in Chlamydia trachomatis Entry

Cherilyn A. Elwell, Alhaji Ceesay, Jung Hwa Kim, Daniel Kalman, Joanne N. Engel

PLOS Pathogens: published March 7, 2008 | https://doi.org/10.1371/journal.ppat.1000021

Related Articles

  1. Correction: RNA Interference Screen Identifies Abl Kinase and PDGFR Signaling in Chlamydia trachomatis Entry

SNARE Protein Mimicry by an Intracellular Bacterium

Cédric Delevoye, Michael Nilges, Pierre Dehoux, Fabienne Paumet, Stéphanie Perrinet, Alice Dautry-Varsat, Agathe Subtil

PLOS Pathogens: published March 14, 2008 | https://doi.org/10.1371/journal.ppat.1000022

Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity

Robert W. Thompson, John T. Pesce, Thirumalai Ramalingam, Mark S. Wilson, Sandy White, Allen W. Cheever, Stacy M. Ricklefs, Stephen F. Porcella, Lili Li, Lesley G. Ellies, Thomas A. Wynn

PLOS Pathogens: published March 14, 2008 | https://doi.org/10.1371/journal.ppat.1000023

Genotype-by-Environment Interactions and Adaptation to Local Temperature Affect Immunity and Fecundity in Drosophila melanogaster

Brian P. Lazzaro, Heather A. Flores, James G. Lorigan, Christopher P. Yourth

PLOS Pathogens: published March 14, 2008 | https://doi.org/10.1371/journal.ppat.1000025

Pneumococcal Pili Are Composed of Protofilaments Exposing Adhesive Clusters of Rrg A

Markus Hilleringmann, Fabiola Giusti, Barbara C. Baudner, Vega Masignani, Antonello Covacci, Rino Rappuoli, Michèle A. Barocchi, Ilaria Ferlenghi

PLOS Pathogens: published March 21, 2008 | https://doi.org/10.1371/journal.ppat.1000026

HTLV-1 Integration into Transcriptionally Active Genomic Regions Is Associated with Proviral Expression and with HAM/TSP

Kiran N. Meekings, Jeremy Leipzig, Frederic D. Bushman, Graham P. Taylor, Charles R. M. Bangham

PLOS Pathogens: published March 21, 2008 | https://doi.org/10.1371/journal.ppat.1000027

Beyond PrPres Type 1/Type 2 Dichotomy in Creutzfeldt-Jakob Disease

Emmanuelle Uro-Coste, Hervé Cassard, Stéphanie Simon, Séverine Lugan, Jean-Marc Bilheude, Armand Perret-Liaudet, James W. Ironside, Stéphane Haik, Christelle Basset-Leobon, Caroline Lacroux, Katell Peoch', Nathalie Streichenberger, Jan Langeveld, Mark W. Head, Jacques Grassi, Jean-Jacques Hauw, Francois Schelcher, Marie Bernadette Delisle, Olivier Andréoletti

PLOS Pathogens: published March 14, 2008 | https://doi.org/10.1371/journal.ppat.1000029

RNAi Screen Reveals an Abl Kinase-Dependent Host Cell Pathway Involved in Pseudomonas aeruginosa Internalization

Julia F. Pielage, Kimberly R. Powell, Daniel Kalman, Joanne N. Engel

PLOS Pathogens: published March 21, 2008 | https://doi.org/10.1371/journal.ppat.1000031

Regulation of Hepatitis C Virion Production via Phosphorylation of the NS5A Protein

Timothy L. Tellinghuisen, Katie L. Foss, Jason Treadaway

PLOS Pathogens: published March 21, 2008 | https://doi.org/10.1371/journal.ppat.1000032

Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage

Denis R. Chopera, Zenda Woodman, Koleka Mlisana, Mandla Mlotshwa, Darren P. Martin, Cathal Seoighe, Florette Treurnicht, Debra Assis de Rosa, Winston Hide, Salim Abdool Karim, Clive M. Gray, Carolyn Williamson, and the CAPRISA 002 Study Team

PLOS Pathogens: published March 21, 2008 | https://doi.org/10.1371/journal.ppat.1000033

The Influence of Host and Bacterial Genotype on the Development of Disseminated Disease with Mycobacterium tuberculosis

Maxine Caws, Guy Thwaites, Sarah Dunstan, Thomas R. Hawn, Nguyen Thi Ngoc Lan, Nguyen Thuy Thuong Thuong, Kasia Stepniewska, Mai Nguyet Thu Huyen, Nguyen Duc Bang, Tran Huu Loc, Sebastien Gagneux, Dick van Soolingen, Kristin Kremer, Marianne van der Sande, Peter Small, Phan Thi Hoang Anh, Nguyen Tran Chinh, Hoang Thi Quy, Nguyen Thi Hong Duyen, Dau Quang Tho, Nguyen T. Hieu, Estee Torok, Tran Tinh Hien, Nguyen Huy Dung, Nguyen Thi Quynh Nhu, Phan Minh Duy, Nguyen van Vinh Chau, Jeremy Farrar

PLOS Pathogens: published March 28, 2008 | https://doi.org/10.1371/journal.ppat.1000034

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

Nicole Appel, Margarita Zayas, Sven Miller, Jacomine Krijnse-Locker, Torsten Schaller, Peter Friebe, Stephanie Kallis, Ulrike Engel, Ralf Bartenschlager

PLOS Pathogens: published March 28, 2008 | https://doi.org/10.1371/journal.ppat.1000035