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Open Access
Peer-reviewed
Research Article
RNAi screening of uncharacterized genes identifies promising druggable targets in Schistosoma japonicum
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Yuxiang Xie,
Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Xiaoling Wang,
Roles Resources, Software
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Shaoyun Cheng,
Roles Resources, Software
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Wanling Liu,
Roles Resources
Affiliation Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China
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Cun Yi,
Roles Resources
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Yanmin You,
Roles Resources
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Wei Zhang,
Roles Resources
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Yuepeng Wang,
Roles Resources
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Enlu Tang,
Roles Resources
Affiliation College of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, China
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Jipeng Wang ,
Roles Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: huw@fudan.edu.cn (WH), jipengwang@fudan.edu.cn (JW)
Affiliation State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China
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Wei Hu
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: huw@fudan.edu.cn (WH), jipengwang@fudan.edu.cn (JW)
Affiliations State Key Laboratory of Genetic Engineering, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China, Department of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China, College of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, China, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, China
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RNAi screening of uncharacterized genes identifies promising druggable targets in Schistosoma japonicum
- Yuxiang Xie,
- Xiaoling Wang,
- Shaoyun Cheng,
- Wanling Liu,
- Cun Yi,
- Yanmin You,
- Wei Zhang,
- Yuepeng Wang,
- Enlu Tang,
- Jipeng Wang
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- Published: March 28, 2025
- https://doi.org/10.1371/journal.ppat.1013014