Leishmania major Dihydrolipoyl dehydrogenase (DLD) is a key metabolic enzyme that drives parasite proliferation, pathology and host immune response

• Somtochukwu S. Onwah,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Zhirong Mou,

  Roles Methodology, Supervision

  Affiliation Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Gaurav Gupta,

  Roles Methodology, Supervision

  Affiliation Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Patience Obi,

  Roles Methodology

  Affiliation Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada

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• Nnamdi Ikeogu,

  Roles Methodology

  Affiliation Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Ping Jia,

  Roles Methodology, Supervision

  Affiliation Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Wen-Wei Zhang,

  Roles Methodology

  Affiliation Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada

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• Saeid Ghavami,

  Roles Formal analysis, Methodology

  Affiliation Department of Human Anatomy and Cell Science, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Ayesha Saleem,

  Roles Methodology, Software

  Affiliation Faculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, Manitoba, Canada

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• Jude Uzonna

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: jude.uzonna@umanitoba.ca

  Affiliations Department of Immunology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Medical Microbiology and Infectious Diseases, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Pathology, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

  https://orcid.org/0000-0003-2759-0664

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