Breakthrough infection elicits hypermutated IGHV3-53/3-66 public antibodies with broad and potent neutralizing activity against SARS-CoV-2 variants including the emerging EG.5 lineages

• Ling Li ,

  Contributed equally to this work with: Ling Li, Xixian Chen

  Roles Funding acquisition, Investigation, Validation, Writing – review & editing

  Affiliation Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China

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• Xixian Chen ,

  Contributed equally to this work with: Ling Li, Xixian Chen

  Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliations Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China, University of Science and Technology of China, Hefei, People’s Republic of China

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• Zuowei Wang,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China

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• Yunjian Li,

  Roles Investigation, Software, Validation, Visualization, Writing – review & editing

  Affiliation Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China

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• Chen Wang,

  Roles Investigation

  Affiliation Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China

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• Liwei Jiang ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: jlw0531@cmpt.ac.cn (LJ); zuot@cmpt.ac.cn (TZ)

  Affiliation Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China

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• Teng Zuo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jlw0531@cmpt.ac.cn (LJ); zuot@cmpt.ac.cn (TZ)

  Affiliation Laboratory of Immunoengineering, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, People’s Republic of China

  https://orcid.org/0009-0002-7399-3229

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