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Open Access
Peer-reviewed
Research Article
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection
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Olivia E. Harwood,
Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Lea M. Matschke,
Roles Formal analysis, Investigation, Methodology
Affiliation Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Ryan V. Moriarty,
Roles Data curation
Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Alexis J. Balgeman,
Roles Investigation
Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Abigail J. Weaver,
Roles Investigation
Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Amy L. Ellis-Connell,
Roles Conceptualization, Writing – review & editing
Affiliation Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Andrea M. Weiler,
Roles Investigation
Affiliation Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America
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Lee C. Winchester,
Roles Investigation
Affiliation College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Courtney V. Fletcher,
Roles Supervision
Affiliation College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America
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Thomas C. Friedrich,
Roles Supervision
Affiliations Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America
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Brandon F. Keele,
Roles Resources
Affiliation AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America
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David H. O’Connor,
Roles Conceptualization, Resources
Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America
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Jessica D. Lang,
Roles Data curation, Formal analysis
Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Center for Human Genomics and Precision Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Matthew R. Reynolds,
Roles Supervision
Affiliations Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America
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Shelby L. O’Connor
Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing
* E-mail: slfeinberg@wisc.edu
Affiliations Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Wisconsin National Primate Research Center, Madison, Wisconsin, United States of America
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CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection
- Olivia E. Harwood,
- Lea M. Matschke,
- Ryan V. Moriarty,
- Alexis J. Balgeman,
- Abigail J. Weaver,
- Amy L. Ellis-Connell,
- Andrea M. Weiler,
- Lee C. Winchester,
- Courtney V. Fletcher,
- Thomas C. Friedrich
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- Published: September 25, 2023
- https://doi.org/10.1371/journal.ppat.1011676