RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature

Coralie Viollet; David A. Davis; Shewit S. Tekeste; Martin Reczko; Joseph M. Ziegelbauer; Francesco Pezzella; Jiannis Ragoussis; Robert Yarchoan

doi:10.1371/journal.ppat.1006143

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Open Access

Peer-reviewed

Research Article

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature

Coralie Viollet,

Affiliations HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America, The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
David A. Davis,

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Shewit S. Tekeste,

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Martin Reczko,

Affiliation Institute of Molecular Oncology, Alexander Fleming Biomedical Sciences Research Center, Vari, Greece
⨯
Joseph M. Ziegelbauer,

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

http://orcid.org/0000-0001-6464-6941

⨯
Francesco Pezzella,

Affiliation Nuffield Division of Clinical Laboratory Sciences, University of Oxford, Oxford, United Kingdom
⨯
Jiannis Ragoussis,

Affiliations The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Institute of Molecular Oncology, Alexander Fleming Biomedical Sciences Research Center, Vari, Greece, McGill University and Génome Québec Innovation Centre, Montréal, Québec, Canada, Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia
⨯
Robert Yarchoan

* E-mail: robert.yarchoan@nih.gov

Affiliation HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature

Coralie Viollet,
David A. Davis,
Shewit S. Tekeste,
Martin Reczko,
Joseph M. Ziegelbauer,
Francesco Pezzella,
Jiannis Ragoussis,
Robert Yarchoan

Published: January 3, 2017
https://doi.org/10.1371/journal.ppat.1006143

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Hypoxia
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MicroRNAs
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Kaposi's sarcoma-associated herpesvirus
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Gene expression
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RNA sequencing
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Transfection
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Cancers and neoplasms
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Viral gene expression
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