A Mechanism for the Inhibition of DNA-PK-Mediated DNA Sensing by a Virus

Nicholas E. Peters; Brian J. Ferguson; Michela Mazzon; Aodhnait S. Fahy; Ewelina Krysztofinska; Raquel Arribas-Bosacoma; Laurence H. Pearl; Hongwei Ren; Geoffrey L. Smith

doi:10.1371/journal.ppat.1003649

Loading metrics

Open Access

Peer-reviewed

Research Article

A Mechanism for the Inhibition of DNA-PK-Mediated DNA Sensing by a Virus

Nicholas E. Peters,

Affiliation Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom
⨯
Brian J. Ferguson,

Affiliations Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom, Department of Pathology, Cambridge University, Cambridge, United Kingdom
⨯
Michela Mazzon,

Affiliations Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom, Department of Pathology, Cambridge University, Cambridge, United Kingdom
⨯
Aodhnait S. Fahy,

Affiliation Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom
⨯
Ewelina Krysztofinska,

Affiliation Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom
⨯
Raquel Arribas-Bosacoma,

Affiliation Cancer Research UK DNA Repair Enzymes Group, Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Laurence H. Pearl,

Affiliation Cancer Research UK DNA Repair Enzymes Group, Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, United Kingdom
⨯
Hongwei Ren,

Affiliations Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom, Department of Pathology, Cambridge University, Cambridge, United Kingdom
⨯
Geoffrey L. Smith

* E-mail: gls37@cam.ac.uk

Affiliations Section of Virology, Department of Medicine, Imperial College London, Norfolk Place, London, United Kingdom, Department of Pathology, Cambridge University, Cambridge, United Kingdom
⨯

A Mechanism for the Inhibition of DNA-PK-Mediated DNA Sensing by a Virus

Nicholas E. Peters,
Brian J. Ferguson,
Michela Mazzon,
Aodhnait S. Fahy,
Ewelina Krysztofinska,
Raquel Arribas-Bosacoma,
Laurence H. Pearl,
Hongwei Ren,
Geoffrey L. Smith

Published: October 3, 2013
https://doi.org/10.1371/journal.ppat.1003649

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Immune response
Is the Subject Area "Immune response" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Innate immune system
Is the Subject Area "Innate immune system" applicable to this article?

Thanks for your feedback.
Vaccinia virus
Is the Subject Area "Vaccinia virus" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Immune system proteins
Is the Subject Area "Immune system proteins" applicable to this article?

Thanks for your feedback.
DNA-binding proteins
Is the Subject Area "DNA-binding proteins" applicable to this article?

Thanks for your feedback.
Viral genomics
Is the Subject Area "Viral genomics" applicable to this article?

Thanks for your feedback.