About the Authors

Erhard van der Vries

Affiliation Erasmus Medical Centre, Department of Virology, Rotterdam, The Netherlands

Patrick J. Collins

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Sebastien G. Vachieri

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Xiaoli Xiong

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Junfeng Liu

Affiliations Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom, MOA Key Laboratory of Plant Pathology, China Agricultural University, Beijing, People's Republic of China

Philip A. Walker

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Lesley F. Haire

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Alan J. Hay

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Martin Schutten

Affiliation Erasmus Medical Centre, Department of Virology, Rotterdam, The Netherlands

Albert D. M. E. Osterhaus

Affiliation Erasmus Medical Centre, Department of Virology, Rotterdam, The Netherlands

Steve R. Martin

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Charles A. B. Boucher

Affiliation Erasmus Medical Centre, Department of Virology, Rotterdam, The Netherlands

John J. Skehel

skeheljj@nimr.mrc.ac.uk

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Steve J. Gamblin

Affiliation Medical Research Council, National Institute for Medical Research, The Ridgeway, Mill Hill, London, United Kingdom

Competing Interests

I have read the journal's policy and have the following conflicts: MS is consultant of ViroClinics Biosciences BV. MS is advisor for Hoffmann-La Roche, Inc. MS is advisor for Vertex Ltd. ADMEO is employe of ViroClinics Biosciences BV. ADMEO is chief scientific officer of ViroClinics Biosciences BV. ADMEO, MS, EVDV and CABB participate in the IRIS study sponsored by Hoffmann-La Roche, Inc. This does not alter our adherence to all PLoS Pathogens policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EVDV PJC SGV XX ADMEO CABB JJS SJG. Performed the experiments: EVDV PJC SGV XX JL PAW LFH SRM JJS SJG. Analyzed the data: EVDV PJC SGV XX JL PAW LFH SRM JJS SJG. Contributed reagents/materials/analysis tools: EVDV PJC SBV XX JL PAW LFH AJH MS SRM CABB JJS SJG. Wrote the paper: EVDV JJS SJG CABB.