This month's Editorial, a collaborative statement by editors from Medical Decision Making, Trials, The Cochrane Library, Journal of Clinical Epidemiology, and PLoS Medicine, calls for standards in the conduct and reporting of comparative effectiveness research (CER). To optimize health outcomes within the constraints of inevitably limited resources, low- and high-income countries alike require unbiased means of assessing health care interventions for their relative effectiveness. Providing specific principles and standards for CER, the journal editors emphasize that researchers must adopt stringent methods, and medical journals must maintain high criteria for ethics, scientific rigor, and reporting, in order to fulfill the potential of research to improve decision making in health care. This statement has also been endorsed by the editors of Journal of General Internal Medicine, The American Journal of Managed Care, Clinical and Translational Science, and Croatian Medical Journal, and will be co-published in Medical Decision Making, Croatian Medical Journal, The Cochrane Library, Trials, The American Journal of Managed Care, and Journal of Clinical Epidemiology.
Image Credit: Collage created by Katie Hickling, PLoS. Original images by southerntabitha, taberandrew, FeatheredTar, Seattle Municipal Archives, VinceHuang, jen_rab, isafmedia, and dbdbrobot, all on flickr.com.
Editorial
Comparative Effectiveness Research: Challenges for Medical Journals
PLOS Medicine: published April 27, 2010 | https://doi.org/10.1371/journal.pmed.1000269
Perspectives
Does Seasonal Influenza Vaccination Increase the Risk of Illness with the 2009 A/H1N1 Pandemic Virus?
PLOS Medicine: published April 6, 2010 | https://doi.org/10.1371/journal.pmed.1000259
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Mortality Measurement Matters: Improving Data Collection and Estimation Methods for Child and Adult Mortality
PLOS Medicine: published April 13, 2010 | https://doi.org/10.1371/journal.pmed.1000265
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Policy Forums
Improving Newborn Survival in Low-Income Countries: Community-Based Approaches and Lessons from South Asia
PLOS Medicine: published April 6, 2010 | https://doi.org/10.1371/journal.pmed.1000246
Health Diplomacy and the Enduring Relevance of Foreign Policy Interests
PLOS Medicine: published April 20, 2010 | https://doi.org/10.1371/journal.pmed.1000226
China's Engagement with Global Health Diplomacy: Was SARS a Watershed?
PLOS Medicine: published April 27, 2010 | https://doi.org/10.1371/journal.pmed.1000266
Brazil and the Framework Convention on Tobacco Control: Global Health Diplomacy as Soft Power
PLOS Medicine: published April 20, 2010 | https://doi.org/10.1371/journal.pmed.1000232
Research Articles
Association between the 2008–09 Seasonal Influenza Vaccine and Pandemic H1N1 Illness during Spring–Summer 2009: Four Observational Studies from Canada
PLOS Medicine: published April 6, 2010 | https://doi.org/10.1371/journal.pmed.1000258
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Economic Appraisal of Ontario's Universal Influenza Immunization Program: A Cost-Utility Analysis
PLOS Medicine: published April 6, 2010 | https://doi.org/10.1371/journal.pmed.1000256
Early Emergence of Ethnic Differences in Type 2 Diabetes Precursors in the UK: The Child Heart and Health Study in England (CHASE Study)
PLOS Medicine: published April 20, 2010 | https://doi.org/10.1371/journal.pmed.1000263
The Effect of Rural-to-Urban Migration on Obesity and Diabetes in India: A Cross-Sectional Study
PLOS Medicine: published April 27, 2010 | https://doi.org/10.1371/journal.pmed.1000268
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Alternative Strategies to Reduce Maternal Mortality in India: A Cost-Effectiveness Analysis
PLOS Medicine: published April 20, 2010 | https://doi.org/10.1371/journal.pmed.1000264
Preoperative/Neoadjuvant Therapy in Pancreatic Cancer: A Systematic Review and Meta-analysis of Response and Resection Percentages
PLOS Medicine: published April 20, 2010 | https://doi.org/10.1371/journal.pmed.1000267
What Can We Conclude from Death Registration? Improved Methods for Evaluating Completeness
PLOS Medicine: published April 13, 2010 | https://doi.org/10.1371/journal.pmed.1000262
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Measuring Adult Mortality Using Sibling Survival: A New Analytical Method and New Results for 44 Countries, 1974–2006
PLOS Medicine: published April 13, 2010 | https://doi.org/10.1371/journal.pmed.1000260
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Measuring Under-Five Mortality: Validation of New Low-Cost Methods
PLOS Medicine: published April 13, 2010 | https://doi.org/10.1371/journal.pmed.1000253