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Rare but elevated incidence of hematological malignancy after clozapine use in schizophrenia: A population cohort study
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Yuqi Hu ,
Contributed equally to this work with: Yuqi Hu, Le Gao
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft
Affiliation Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
⨯ -
Le Gao ,
Contributed equally to this work with: Yuqi Hu, Le Gao
Roles Data curation, Formal analysis, Methodology
Affiliations Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, Department of Pharmacy Administration, School of Pharmacy, Xi’an Jiaotong University, Shaanxi, China, Center for Drug Safety and Policy Research, Xi’an Jiaotong University, Shaanxi, China
⨯ -
Lingyue Zhou,
Roles Writing – review & editing
Affiliation Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
⨯ - Wenlong Liu,
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Cuiling Wei,
Roles Writing – review & editing
Affiliation Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
⨯ - Boyan Liu,
- Qi Sun,
- Wenxin Tian,
- Rachel Yui Ki Chu,
- Song Song,
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Franco Wing Tak Cheng,
Roles Writing – review & editing
Affiliation Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
⨯ - Joe Kwun Nam Chan,
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Amy Pui Pui Ng,
Roles Writing – review & editing
Affiliation Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
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Heidi Ka Ying Lo,
Roles Writing – review & editing
Affiliation Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
⨯ -
Krystal Chi Kei Lee,
Roles Writing – review & editing
Affiliation Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
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Wing Chung Chang,
Roles Writing – review & editing
Affiliations Department of Psychiatry, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, State Key Laboratory of Brain & Cognitive Sciences, the University of Hong Kong, Hong Kong SAR
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William Chi Wai Wong,
Roles Writing – review & editing
Affiliation Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR
⨯ -
Esther Wai Yin Chan,
Roles Writing – review & editing
Affiliations Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Sha Tin, Hong Kong SAR
⨯ -
Ian Chi Kei Wong,
Roles Writing – review & editing
Affiliations Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Sha Tin, Hong Kong SAR, Advanced Data Analytics for Medical Science (ADAMS) Limited, Hong Kong SAR, Aston Pharmacy School, Aston University Birmingham, Birmingham, United Kingdom
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Yi Chai ,
Roles Data curation, Formal analysis, Methodology, Writing – review & editing
* E-mail: ychai@szu.edu.cn (YC); fttlai@hku.hk (FTTL)
¶‡ These authors are joint senior authors on this work.
Affiliations Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, The Hong Kong Jockey Club Centre for Suicide Research and Prevention, The University of Hong Kong, Hong Kong SAR, School of Public Health, Shenzhen University Medical School, Shenzhen University, Shenzhen, China
⨯ - [ ... ],
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Francisco Tsz Tsun Lai
Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing
* E-mail: ychai@szu.edu.cn (YC); fttlai@hku.hk (FTTL)
¶‡ These authors are joint senior authors on this work.
Affiliations Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, Laboratory of Data Discovery for Health (D24H), Hong Kong Science Park, Sha Tin, Hong Kong SAR, Department of Family Medicine and Primary Care, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, Advanced Data Analytics for Medical Science (ADAMS) Limited, Hong Kong SAR
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https://orcid.org/0009-0000-2577-6882
Rare but elevated incidence of hematological malignancy after clozapine use in schizophrenia: A population cohort study
- Yuqi Hu,
- Le Gao,
- Lingyue Zhou,
- Wenlong Liu,
- Cuiling Wei,
- Boyan Liu,
- Qi Sun,
- Wenxin Tian,
- Rachel Yui Ki Chu,
- Song Song
- Published: December 5, 2024
- https://doi.org/10.1371/journal.pmed.1004457