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July 2024

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Every year, hundreds of thousands of people worldwide are killed, disabled, or disfigured by bites from venomous snakes. What sorts of obstacles do snakebite victims face in their search for antivenom? And why do people choose traditional remedies, such as homeopathic treatments, even though these have limited evidence of effectiveness against snakebite envenoming? By taking an intercultural approach, which emphasizes mutual respect and understanding between Western and indigenous health belief systems, Vasquez, Castro & Carter look to answer these questions.

Image Credit: Leonardo Fernández Badillo

Viewpoints

Rocky Mountain spotted fever is a neglected tropical disease in Latin America

Gerardo Álvarez-Hernández, Christopher D. Paddock, David H. Walker, Jesus G. Valenzuela, J. R. Tadeo Calleja-López, Cristian Noé Rivera-Rosas, Rogerio Rafael Sotelo-Mundo

Is there a lack of a glucose monitoring and management protocol for preventing hyperglycemia and glucocorticoid-induced diabetes mellitus in leprosy reactions?

Douglas Eulálio Antunes, Diogo Fernandes dos Santos, Jaqueline Andreoli Thomazelli, Cassio Martins Leite, Isabela Maria Bernardes Goulart

Reviews

Challenges for ticks and tick-borne diseases research in Southeast Asia: Insight from the first international symposium in Cambodia

Sony Yean, Didot Budi Prasetyo, Sebastien Marcombe, Upik Kesumawati Hadi, Abdul Rahman Kazim, Sonthaya Tiawsirisup, Vu Duc Chinh, Keita Matsuno, Van Lun Low, Sarah Bonnet, Nathalie Boulanger, Tommy Tsan-Yuk Lam, Mohammad Yazid Abdad, Vincent Herbreteau, Jean-Marc Chavatte, Samuth Sum, Theary Ren, Anavaj Sakuntabhai, Pierre-Olivier Maquart, Antsa Rakotonirina, Sebastien Boyer

Schistosomiasis diagnosis: Challenges and opportunities for elimination

Ombeni Ally, Bernard N. Kanoi, Lucy Ochola, Steven Ger Nyanjom, Clement Shiluli, Gerald Misinzo, Jesse Gitaka

Research Articles

Assessing the modification impact of vaccination on the relationship of the Discomfort Index with hand, foot, and mouth disease in Guizhou: A multicounty study

Jie Sun, Wangjian Zhang, Guanghai Yao, Jing Gu, Wenjing Wu, Dan Wang, Zhicheng Du, Yuantao Hao

A Nanobody/Monoclonal Antibody “hybrid” sandwich technology offers an improved immunoassay strategy for detection of African trypanosome infections

Steven Odongo, Bo-Kyung Jin, Hang Thi Thu Nguyen, Magdalena Radwanska, Stefan Magez

Postnatal zinc deficiency due to giardiasis disrupts hippocampal and cerebellar development

Angélica González Maciel, Laura Elizabeth Rosas López, Rosa María Romero-Velázquez, Andrea Ramos-Morales, Martha Ponce-Macotela, David Calderón-Guzmán, Francisca Trujillo-Jiménez, Alfonso Alfaro-Rodríguez, Rafael Reynoso-Robles

Schistosoma haematobium and Schistosoma bovis first generation hybrids undergo gene expressions changes consistent with species compatibility and heterosis

Eglantine Mathieu-Bégné, Julien Kincaid-Smith, Cristian Chaparro, Jean-François Allienne, Olivier Rey, Jérôme Boissier, Eve Toulza

Field- and laboratory-based studies on correlates of Chlamydia trachomatis transmission by Musca sorbens: Determinants of fly-eye contact and investigations into fly carriage of elementary bodies

Ailie Robinson, Bart Versteeg, Oumer Shafi Abdurahman, Innes Clatworthy, Gemeda Shuka, Dereje Debela, Gebreyes Hordofa, Laura Reis de Oliveira Gomes, Muluadam Abraham Aga, Gebeyehu Dumessa, Virginia Sarah, David Macleod, Anna Last, Matthew J. Burton, James G. Logan

Plasmodium vivax populations in the western Greater Mekong Subregion evaluated using a genetic barcode

Yubing Hu, Yuling Li, Awtum M. Brashear, Weilin Zeng, Zifang Wu, Lin Wang, Haichao Wei, Myat Thu Soe, Pyae Linn Aung, Jetsumon Sattabongkot, Myat Phone Kyaw, Zhaoqing Yang, Yan Zhao, Liwang Cui, Yaming Cao

Improved water supply infrastructure to reduce acute diarrhoeal diseases and cholera in Uvira, Democratic Republic of the Congo: Results and lessons learned from a pragmatic trial

Karin Gallandat, Amy Macdougall, Aurélie Jeandron, Jaime Mufitini Saidi, Baron Bashige Rumedeka, Espoir Bwenge Malembaka, Andrew S. Azman, Didier Bompangue, Simon Cousens, Elizabeth Allen, Oliver Cumming

Prevalence and transmission of the most relevant zoonotic and vector-borne pathogens in the Yucatan peninsula: A review

Ma. Fernanda Sánchez-Soto, Osiris Gaona, Ana Laura Vigueras-Galván, Gerardo Suzán, Luisa I. Falcón, Ella Vázquez-Domínguez

Case detection delay in leprosy: Testing tool reliability and measurement consistency in Ethiopia, Mozambique, and Tanzania

Ephrem Mamo, Robin van Wijk, Anne Schoenmakers, Kidist Bobosha, Mengistu Legesse, Thomas Hambridge, Kitesa Debelo, Fufa Daba, Nelly Mwageni, Abdoulaye Marega, Taye Letta, Ahmed Mohammed Eman, Banú Fumane, Helder Rassolo, Blasdus Franz Njako, Stephen E. Mshana, Jan Hendrik Richardus, Christa Kasang, Liesbeth Mieras

Serological diagnosis of strongyloidiasis: An evaluation of three commercial assays

Thomas Weitzel, Sabine Dittrich, Frank P. Mockenhaupt, Andreas K. Lindner

Therapeutic itineraries of snakebite victims and antivenom access in southern Mexico

Chloe Vasquez, Edgar Neri Castro, Eric D. Carter

Replication properties of a contemporary Zika virus from West Africa

Dana Machmouchi, Marie-Pierre Courageot, Chaker El-Kalamouni, Alain Kohl, Philippe Desprès

Glucose transporters and sodium glucose co-transporters cooperatively import glucose into energy-demanding organs in carcinogenic liver fluke Clonorchis sinensis

Fuhong Dai, Soon-Ok Lee, Jin-Ho Song, Won-Gi Yoo, Eun-Hee Shin, Xuelian Bai, Sung-Jong Hong

The effect of repeat feeding on dengue virus transmission potential in Wolbachia-infected Aedes aegypti following extended egg quiescence

Meng-Jia Lau, Andrés R. Valdez, Matthew J. Jones, Igor Aranson, Ary A. Hoffmann, Elizabeth A. McGraw

Molecular surveillance of zoonotic pathogens from wild rodents in the Republic of Korea

Kyoung-Seong Choi, Sunwoo Hwang, Myung Cheol Kim, Hyung-Chul Cho, Yu-Jin Park, Min-Jeong Ji, Sun-Woo Han, Joon-Seok Chae

Widespread human exposure to ledanteviruses in Uganda: A population study

James G. Shepherd, Shirin Ashraf, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Robert G. Downing, Henry Bukenya, Hanna Jerome, Joseph T. Mpanga, Chris Davis, Lily Tong, Vattipally B. Sreenu, Linda A. Atiku, Nicola Logan, Ezekiel Kajik, Yafesi Mukobi, Cyrus Mungujakisa, Michael V. Olowo, Emmanuel Tibo, Fred Wunna, Hollie Jackson Ireland, Andrew E. Blunsum, Iyanuoluwani Owolabi, Ana da Silva Filipe, Josephine Bwogi, Brian J. Willett, Julius J. Lutwama, Daniel G. Streicker, Pontiano Kaleebu, Emma C. Thomson

Triple-drug therapy with ivermectin, diethylcarbamazine and albendazole for the acceleration of lymphatic filariasis elimination in Kenya: Programmatic implementation and results of the first impact assessment

Sammy M. Njenga, Henry Kanyi, Collins Okoyo, Edward Githinji, Cassian Mwatele, Sultani H. Matendechero, Wyckliff P. Omondi, Patrick N. Gitahi, Chrispin Owaga, Joyce K. Onsongo, Katherine Gass

Genetic diversity of enteric viruses responsible of gastroenteritis in urban and rural Burkina Faso

Ange Oho Roseline Badjo, Sandra Niendorf, Sonja Jacobsen, Arsène Zongo, Andreas Mas Marques, Ann Christin Vietor, Nongodo Firmin Kabore, Armel Poda, Satouro Arsène Some, Aminata Ouattara, Soumeya Ouangraoua, Grit Schubert, Tim Eckmanns, Fabian H. Leendertz, Essia Belarbi, Abdoul-Salam Ouedraogo

Blastocystis colonization and associations with population parameters in Thai adults

Vasana Jinatham, Amara Yowang, Christen Rune Stensvold, Eleni Michalopoulou, Thanakrit Vichasilp, Picha Suwannahitatorn, Siam Popluechai, Anastasios D. Tsaousis, Eleni Gentekaki

Ixodes ricinus as potential vector for Usutu virus

Julian W. Bakker, Emmanuelle Münger, Helen J. Esser, Reina S. Sikkema, Willem F. de Boer, Hein Sprong, Chantal B. E. M. Reusken, Ankje de Vries, Robert Kohl, Anne van der Linden, Arjan Stroo, Henk van der Jeugd, Gorben P. Pijlman, Marion P. G. Koopmans, Bas B. Oude Munnink, Constantianus J. M. Koenraadt

Plasmodium vivax genomic surveillance in the Peruvian Amazon with Pv AmpliSeq assay

Johanna Helena Kattenberg, Luis Cabrera-Sosa, Erick Figueroa-Ildefonso, Mathijs Mutsaers, Pieter Monsieurs, Pieter Guetens, Berónica Infante, Christopher Delgado-Ratto, Dionicia Gamboa, Anna Rosanas-Urgell

Revealing the dynamic whole transcriptome landscape of Clonorchis sinensis: Insights into the regulatory roles of noncoding RNAs and microtubule-related genes in development

Yangyuan Qiu, Cunzhou Wang, Jing Wang, Qingbo L. V., Lulu Sun, Yaming Yang, Mingyuan Liu, Xiaolei Liu, Chen Li, Bin Tang

Photographic grading to evaluate facial cleanliness and trachoma among children in Amhara region, Ethiopia

Ramoncito L. Caleon, Fisseha Admassu, Solomon Aragie, Dagnachew Hailu, Adane Dagnew, Taye Zeru, Dionna M. Wittberg, Isabel J. B. Thompson, Seid Abdu, Social Beyecha, Tibebe Birhanu, Habib Getachew, Banchalam Getnet, Endale Kabtu, Meskerem Shibiru, Solomon Tekew, Bilen Wondimteka, Thomas M. Lietman, Scott D. Nash, Matthew C. Freeman, Jeremy D. Keenan

The enhancive effect of the 2014–2016 El Niño-induced drought on the control of soil-transmitted helminthiases without anthelmintics: A longitudinal study

Attarat Pattanawongsa, Pattanasak Kammaneechan, Prasit Na-ek, Blego Sedionoto, Witthaya Anamnart

Knowledge, attitudes and practices toward female genital schistosomiasis among community women and healthcare professionals in Kimpese region, Democratic Republic of Congo

Cecilia Wangari Wambui, Joule Madinga, Mercy Gloria Ashepet, Maxson Kenneth Anyolitho, Patrick Mitashi, Tine Huyse

American Cutaneous Leishmaniasis: Imported cases in Berlin 2000–2023

Andreas K. Lindner, Maria Cristina Moreno-del Castillo, Mia Wintel, Gabriela Equihua Martinez, Joachim Richter, Florian Kurth, Frieder Pfäfflin, Thomas Zoller, Maximilian Gertler, Susanne Georgi, Michael Nürnberg, Claudia Hülso, Julian Bernhard, Sarah Konopelska Kotsias, Antonio Seigerschmidt, Welmoed van Loon, Frank Mockenhaupt, Beate Kampmann, Gundel Harms

A sero-epidemiological analysis of Coxiella burnetii infection and its risk factors in livestock from Addis Ababa, Adama, and Modjo abattoirs and pastoral areas of Oromia, Ethiopia

Ashenafi Milkesa, Tesfaye Rufael, Getachew Kinfe, Redeat Belaineh, Abdella Bulbula, Donghee Cho, Mohammed Naimuddin, Teshale Sori, Hunduma Dinka

Community Involvement in Onchocerciasis Post-elimination Surveillance in Bududa District, Eastern Uganda: A cross-sectional study

Annet Tabitha Khainza, David Soita, David Okia, Francis Okello, Joseph KB Matovu, Yovani Lubaale, Edson Byamukama, Ambrose Okibure, Jimmy Patrick Alunyo, Ritah Nantale, Benon Wanume, David Ogutu, David Mukunya, Peter Olupot-Olupot

Mapping the distribution of sandflies and sandfly-associated pathogens in China

Xue-Geng Hong, Ying Zhu, Tao Wang, Jin-Jin Chen, Fang Tang, Rui-Ruo Jiang, Xiao-Fang Ma, Qiang Xu, Hao Li, Li-Ping Wang, Yi Sun, Li-Qun Fang, Wei Liu

Bone and joint infections due to melioidosis; diagnostic and management strategies to optimise outcomes

Parvati Dadwal, Brady Bonner, David Fraser, Jeremy Loveridge, Grant Withey, Arvind Puri, Simon Smith, Josh Hanson

A retrospective analysis thyroid function and ultrasonography in a group of subjects with lepramatous leprosy in Turkey

Zeynep Ozkan, Zekiye Kanat, Ozkan Alatas, Zuhal Karaca Karagoz

Leishmania spp. in equids and their potential vectors in endemic areas of canine leishmaniasis

Mariaelisa Carbonara, Jairo Alfonso Mendoza-Roldan, Marcos Antônio Bezerra-Santos, Pedro Paulo de Abreu Teles, Riccardo Paolo Lia, Francesco Locantore, Roberta Iatta, Petr Volf, Domenico Otranto

Insights into canine rabies vaccination Disparities in Sierra Leone: A cross-sectional household study

Philip P. Mshelbwala, Kinley Wangdi, Joseph A. Bunting-Graden, Saidu Bamayange, Andrew M. Adamu, Suman D. Gupta, Roland Suluku, Cornelius S. Adamu, J. Scott Weese, Charles E. Rupprecht, Nicholas J. Clark

Leishmania infantum infection modulates messenger RNA, microRNA and long non-coding RNA expression in human neutrophils in vitro

Natália Francisco Scaramele, Jéssica Antonini Troiano, Juliana de Souza Felix, Sidnei Ferro Costa, Mariana Cordeiro Almeida, Flávia Regina Florencio de Athayde, Matheus Fujimura Soares, Maria Fernanda da Silva Lopes, Amanda de Oliveira Furlan, Valéria Marçal Felix de Lima, Flavia Lombardi Lopes

Antimicrobial activity of NK cells to Trypanosoma cruzi infected human primary Keratinocytes

Keshia Kroh, Jessica Barton, Helena Fehling, Hanna Lotter, Beate Volkmer, Rüdiger Greinert, Mouna Mhamdi-Ghodbani, Andrea Vanegas Ramirez, Thomas Jacobs, Rosa Isela Gálvez

Zoonotic Sporotrichosis outbreak: Emerging public health threat in the Amazon State, Brazil

Viviany Araujo Mesquita, Sinesio Talhari, André Luiz Leturiondo, Guilherme Caldas de Souza, Euzenio Moreira de Brito, Suanni Lemos de Andrade, Débora Cristina de Lima Fernandes, Maria Zeli Moreira Frota, Rossilene Conceição da Silva Cruz, Juliana de Andrade Rebouças Guimarães, Helio Amante Miot, Carolina Talhari, Valderiza Lourenço Pedrosa

Seasonal life cycle of Pintomyia longiflocosa (Diptera: Psychodidae) under semi-controlled conditions in the Huila state, Colombia

Jennifer Alejandra Vargas Durango, Gelys Igreth Mestre Carillo, Erika Santamaria Herreño, Miguel Angel Beltran Ruiz, Angela Cristina Zapata Lesmes, Astrid Geovana Muñoz Ortiz, Jesús Eduardo Escobar Castro

Impact of ivermectin and vector control on onchocerciasis transmission in Togo: Assessing the empirical evidence on trends in infection and entomological indicators

Natalie V. S. Vinkeles Melchers, Sibabi Agoro, Kwamy Togbey, Koffi Padjoudoum, Ibrahim Gado Telou, Potchoziou Karabou, Touka Djatho, Michel Datagni, Ameyo Monique Dorkenoo, Yao Kassankogno, Rachel Bronzan, Wilma A. Stolk

Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii

Clay D. Jackson-Litteken, Wanfeng Guo, Brandon A. Hogland, C. Tyler Ratliff, LeAnn McFadden, Marissa S. Fullerton, Daniel E. Voth, Ryan O. M. Rego, Jon S. Blevins

Current and lagged associations of meteorological variables and Aedes mosquito indices with dengue incidence in the Philippines

Estrella I. Cruz, Ferdinand V. Salazar, Ariza Minelle A. Aguila, Mary Vinessa Villaruel-Jagmis, Jennifer Ramos, Richard E. Paul

A pilot study of dimeticone oils versus sodium carbonate treatment for tungiasis: A randomized cohort trial in Homa Bay County, Kenya

Kana Suzuki, Yasuhiko Kamiya, Chris Smith, Satoshi Kaneko, Gordon Okomo, Asiko Ongaya, Evans Amukoye

Differentiation in pyroptosis induction by Burkholderia pseudomallei and Burkholderia thailandensis in primary human monocytes, a possible cause of sepsis in acute melioidosis patients

Suphasuta Khongpraphan, Peeraya Ekchariyawat, Sucharat Sanongkiet, Chularat Luangjindarat, Stitaya Sirisinha, Marisa Ponpuak, Panuwat Midoeng, Matsayapan Pudla, Pongsak Utaisincharoen

Frequency, geographical distribution, clinical characteristics, antivenom utilisation and outcomes of King Cobra (Ophiophagus hannah) bites in Malaysia

Asyhok Renault, Vera Effa Rezar Frederic Ng, Wan Chee Goh, Muhammad Nadzmi Hadi Abd Hamid, Annuar Muhammad Zuljamal Osman, Ruth Sabrina Safferi, Zainalabidin Mohamed@Ismail, Ahmad Khaldun Ismail

Clinical characteristics of enteric fever and performance of TUBEX TF IgM test in Indonesian hospitals

Syndi Nurmawati, Anggraini Alam, Hofiya Djauhari, Tuti P. Merati, Pratiwi Sudarmono, Vivi Setiawaty, Dona Arlinda, Retna Indah Sugiyono, Mansyur Arief, Usman Hadi, Abu Tholib Aman, Dewi Lokida, M. Hussein Gasem, Emiliana Tjitra, C. Jason Liang, Aaron Neal, Herman Kosasih, Muhammad Karyana, Chuen-Yen Lau, Bachti Alisjahbana

The evolutionary and molecular history of a chikungunya virus outbreak lineage

Janina Krambrich, Filip Mihalič, Michael W. Gaunt, Jon Bohlin, Jenny C. Hesson, Åke Lundkvist, Xavier de Lamballerie, Cixiu Li, Weifeng Shi, John H.-O. Pettersson

Could prophylactic antivirals reduce dengue incidence in a high-prevalence endemic area?

Yalda Jafari, Oliver J. Brady, Joseph R. Biggs, Le Thuy Lien, Huynh Kim Mai, Hien Anh Thi Nguyen, Marnix Van Loock, Guillermo Herrera-Taracena, Joris Menten, Chihiro Iwasaki, Mizuki Takegata, Noriko Kitamura, Hung Do Thai, Bui Xuan Minh, Kouichi Morita, Dang Duc Anh, Sam Clifford, Kiesha Prem, Julius Hafalla, W. John Edmunds, Lay Myint Yoshida, Martin L. Hibberd, Stéphane Hué

Cost-effectiveness of sentinel screening of endemic diseases alongside malaria diagnosis: A case study in schistosomiasis

Francesco Manca, Giorgio Ciminata, Eleanor Grieve, Julien Reboud, Jonathan Cooper, Emma McIntosh

Knowledge, attitude, and practices of veterinarians towards canine vector-borne pathogens in Sri Lanka

Ushani Atapattu, Vito Colella, Rebecca J. Traub, Anke Wiethoelter

The lethal effect of soap on Schistosoma mansoni cercariae in water

Jiaodi Zhang, Ana K. Pitol, Safari Kinung’hi, Teckla Angelo, Aidan M. Emery, Adam Cieplinski, Michael R. Templeton, Laura Braun

From fangs to antidotes: A scoping review on snakebite burden, species, and antivenoms in the Eastern Mediterranean Region

Ali Alshalah, David J. Williams, Alessandra Ferrario