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April 2024

More than 700,000 people are currently displaced in Cabo Delgado province due to organised armed group attacks. This displacement severely affected the access of internally displaced person to essential healthcare exacerbating the vulnerability to infectious diseases. Badia-Rius et al, 2024.

Image Credit: MUNTI TEC / The MENTOR Initiative

Research Articles

Biased virus transmission following sequential coinfection of Aedes aegypti with dengue and Zika viruses

Jiameng Peng, Meichun Zhang, Gang Wang, Dongjing Zhang, Xiaoying Zheng, Yongjun Li

Venom diversity in Naja mossambica: Insights from proteomic and immunochemical analyses reveal intraspecific differences

Konrad K. Hus, Justyna Buczkowicz, Monika Pietrowska, Vladimír Petrilla, Monika Petrillová, Jaroslav Legáth, Thea Litschka-Koen, Aleksandra Bocian

Impact of Strongyloides stercoralis infection on complement activation in Type 2 diabetes mellitus: Insights from a clinical and anthelmintic intervention study

Anuradha Rajamanickam, Bindu Dasan, Saravanan Munisankar, Sujatha Nott, Pradeep A. Menon, Fayaz Ahamed Shaik, Ponnuraja Chinnaiyan, Thomas B. Nutman, Subash Babu

Domestic dogs in indigenous Amazonian communities: Key players in Leptospira cycling and transmission?

Diego A. Guzmán, Eduardo Diaz, Carolina Sáenz, Hernán Álvarez, Rubén Cueva, Galo Zapata-Ríos, Belén Prado-Vivar, Mercy Falconí, Talima Pearson, Veronica Barragan

Comparative proteomic analysis of the hemolymph and salivary glands of Rhodnius prolixus and R. colombiensis reveals candidates associated with differential lytic activity against Trypanosoma cruzi Dm28c and T. cruzi Y

Hamilton J. Barbosa, Yazmin Suárez Quevedo, Arlid Meneses Torres, Gustavo A. Gaitán Veloza, Julio C. Carranza Martínez, Daniel A. Urrea-Montes, Carlos Robello-Porto, Gustavo A. Vallejo

Amoxicillin/clavulanate in combination with rifampicin/clarithromycin is bactericidal against Mycobacterium ulcerans

Emma Sáez-López, Ana C. Millán-Placer, Ainhoa Lucía, Santiago Ramón-García

Snakebite envenoming: A systematic review and meta-analysis of global morbidity and mortality

Afsana Afroz, Bodrun Naher Siddiquea, Hasina Akhter Chowdhury, Timothy NW Jackson, Andrew D. Watt

Programmatic considerations and evidence gaps for chikungunya vaccine introduction in countries at risk of chikungunya outbreaks: Stakeholder analysis

Megan Auzenbergs, Clara Maure, Hyolim Kang, Andrew Clark, Oliver Brady, Sushant Sahastrabuddhe, Kaja Abbas

Citizens can help to map putative transmission sites for snail-borne diseases

Julius Tumusiime, Noelia Valderrama Bhraunxs, Grace Kagoro-Rugunda, Daisy Namirembe, Christian Albrecht, Ronald Twongyirwe, Casim Umba Tolo, Liesbet Jacobs, Tine Huyse

Serological diagnosis of soil-transmitted helminth (Ascaris, Trichuris and hookworm) infections: A scoping review

Sara Roose, Fiona Vande Velde, Johnny Vlaminck, Peter Geldhof, Bruno Levecke

Transcriptional signatures in human macrophage-like cells infected by Leishmania infantum, Leishmania major and Leishmania tropica

Aurora Diotallevi, Federica Bruno, Germano Castelli, Giuseppe Persico, Gloria Buffi, Marcello Ceccarelli, Daniela Ligi, Ferdinando Mannello, Fabrizio Vitale, Mauro Magnani, Luca Galluzzi

Protoplast-mediated transformation of Madurella mycetomatis using hygromycin resistance as a selection marker

Saskia du Pré, Mickey Konings, Dorenda J. A. Schoorl, Ahmed H. Fahal, Mark Arentshorst, Arthur F. J. Ram, Wendy W. J. van de Sande

Severe leptospirosis in tropical and non-tropical areas: A comparison of two french, multicentre, retrospective cohorts

Jérôme Allyn, Arnaud-Félix Miailhe, Benjamin Delmas, Lucas Marti, Nicolas Allou, Julien Jabot, Jean Reignier

Diagnostic accuracy of DPP Fever Panel II Asia tests for tropical fever diagnosis

Sandhya Dhawan, Sabine Dittrich, Sonia Arafah, Stefano Ongarello, Aurelian Mace, Siribun Panapruksachat, Latsaniphone Boutthasavong, Aphaphone Adsamouth, Soulignasak Thongpaseuth, Viengmon Davong, Manivanh Vongsouvath, Elizabeth A. Ashley, Matthew T. Robinson, Stuart D. Blacksell

Assessing and managing the risk of Aedes mosquito introductions via the global maritime trade network

Janna R. Willoughby, Benjamin A. McKenzie, Jordan Ahn, Todd D. Steury, Christopher A. Lepzcyk, Sarah Zohdy

Comparison of two approaches to measuring clean faces as part of the facial cleanliness component of the SAFE trachoma elimination strategy

Sheila K. West, Beatriz Munoz, Harran Mkocha, Matthew C. Lynch, Catherine Gracewello, Mabula Kasubi, Meraf A. Wolle

Diagnosis of soil-transmitted helminth infections with digital mobile microscopy and artificial intelligence in a resource-limited setting

Johan Lundin, Antti Suutala, Oscar Holmström, Samuel Henriksson, Severi Valkamo, Harrison Kaingu, Felix Kinyua, Martin Muinde, Mikael Lundin, Vinod Diwan, Andreas Mårtensson, Nina Linder

Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen

Houreratou Barry, Edouard Lhomme, Mathieu Surénaud, Moumini Nouctara, Cynthia Robinson, Viki Bockstal, Innocent Valea, Serge Somda, Halidou Tinto, Nicolas Meda, Brian Greenwood, Rodolphe Thiébaut, Christine Lacabaratz

Endemic status of urogenital schistosomiasis and the efficacy of a single-dose praziquantel treatment in unmapped rural farming communities in Oyo East Local Government Area, Oyo State, Nigeria

Alexander B. Odaibo, Adenike K. Komolafe, Taiwo O. Olajumoke, Kanyinsola D. Diyan, Damilare A. Aluko, Oluwatunmininu A. Alagbe, Oluwafemi A. Ajagbe, David B. Olarinloye

Ginkgo biloba attenuated detrimental inflammatory and oxidative events due to Trypanosoma brucei rhodesiense in mice treated with melarsoprol

Janet Khatenje Wendo, James Mucunu Mbaria, James Nyabuga Nyariki, Alfred Orina Isaac

Extant interspecific hybridization among trematodes within the Schistosoma haematobium species complex in Nigeria

Oluwaremilekun G. Ajakaye, Elisha E. Enabulele, Joshua B. Balogun, Oyetunde T. Oyeyemi, Michael E. Grigg

The elimination of human African trypanosomiasis: Monitoring progress towards the 2021–2030 WHO road map targets

Jose R. Franco, Gerardo Priotto, Massimo Paone, Giuliano Cecchi, Agustin Kadima Ebeja, Pere P. Simarro, Dieudonne Sankara, Samia B. A. Metwally, Daniel Dagne Argaw

Machine learning for predicting Chagas disease infection in rural areas of Brazil

Fabio De Rose Ghilardi, Gabriel Silva, Thallyta Maria Vieira, Ariela Mota, Ana Luiza Bierrenbach, Renata Fiuza Damasceno, Lea Campos de Oliveira, Alexandre Dias Porto Chiavegatto Filho, Ester Sabino

Post-kala-azar dermal leishmaniasis (PKDL) drug efficacy study landscape: A systematic scoping review of clinical trials and observational studies to assess the feasibility of establishing an individual participant-level data (IPD) platform

Sauman Singh-Phulgenda, Rishikesh Kumar, Prabin Dahal, Abdalla Munir, Sumayyah Rashan, Rutuja Chhajed, Caitlin Naylor, Brittany J. Maguire, Niyamat Ali Siddiqui, Eli Harriss, Manju Rahi, Fabiana Alves, Shyam Sundar, Kasia Stepniewska, Ahmed Musa, Philippe J. Guerin, Krishna Pandey

Local amphotericin B therapy for Cutaneous Leishmaniasis: A systematic review

Líndicy Leidicy Alves, Mariana Lourenço Freire, Isadora Lana Troian, Eliane de Morais-Teixeira, Gláucia Cota

Schistosome infection among pregnant women in the rural highlands of Madagascar: A cross-sectional study calling for public health interventions in vulnerable populations

Raphäel Rakotozandrindrainy, Rivo Andry Rakotoarivelo, Irina Kislaya, Valentina Marchese, Tahimandranto Rasamoelina, Jeannine Solonirina, Elveric Fesia Ratiaharison, Ravo Razafindrakoto, Nantenaina Matthieu Razafindralava, Njary Rakotozandrindrainy, Mickael Radomanana, Mala Rakoto Andrianarivelo, Philipp Klein, Eva Lorenz, Anna Jaeger, Pytsje T. Hoekstra, Paul L. A. M. Corstjens, Norbert Georg Schwarz, Govert J. van Dam, Jürgen May, Daniela Fusco, on behalf of the freeBILy consortium

Modelled impact of Tiny Targets on the distribution and abundance of riverine tsetse

Glyn A. Vale, John W. Hargrove, Andrew Hope, Steve J. Torr

Association of liver function and prognosis in patients with severe fever with thrombocytopenia syndrome

Shaoqiu Zhang, Jian Wang, Qun Zhang, Yifan Pan, Zhiyi Zhang, Yu Geng, Bei Jia, Yuanyuan Li, Yali Xiong, Xiaomin Yan, Jie Li, Huali Wang, Chao Wu, Rui Huang

Effect of fasting plasma glucose level in severe fever and thrombocytopenia syndrome patients without diabetes

Jun Pan, Zhihao Yang, Wen Xu, Shan Tian, Xiaobo Liu, Chunxia Guo

Dengue vector control in high-income, city settings: A scoping review of approaches and methods

Anna Durrance-Bagale, Nirel Hoe, Jane Lai, Jonathan Wee Kent Liew, Hannah Clapham, Natasha Howard

The Vicious Worm education tool improves the knowledge of community health workers on Taenia solium cysticercosis in Rwanda

Esther Uwibambe, Anselme Shyaka, Egide Niyotwagira, Justine Mutoniwase, Eric M. Fèvre, Rupert J. Quinnell, Chiara Trevisan

Predominance of multidrug-resistant Salmonella Typhi genotype 4.3.1 with low-level ciprofloxacin resistance in Zanzibar

Annette Onken, Sabrina Moyo, Mohammed Khamis Miraji, Jon Bohlin, Msafiri Marijani, Joel Manyahi, Kibwana Omar Kibwana, Fredrik Müller, Pål A. Jenum, Khamis Ali Abeid, Marianne Reimers, Nina Langeland, Kristine Mørch, Bjørn Blomberg

Global seroprevalence of Zika virus in asymptomatic individuals: A systematic review

Paola Mariela Saba Villarroel, Rodolphe Hamel, Nuttamonpat Gumpangseth, Sakda Yainoy, Phanit Koomhin, Dorothée Missé, Sineewanlaya Wichit

Edge Artificial Intelligence (AI) for real-time automatic quantification of filariasis in mobile microscopy

Lin Lin, Elena Dacal, Nuria Díez, Claudia Carmona, Alexandra Martin Ramirez, Lourdes Barón Argos, David Bermejo-Peláez, Carla Caballero, Daniel Cuadrado, Oscar Darias-Plasencia, Jaime García-Villena, Alexander Bakardjiev, Maria Postigo, Ethan Recalde-Jaramillo, Maria Flores-Chavez, Andrés Santos, María Jesús Ledesma-Carbayo, José M. Rubio, Miguel Luengo-Oroz

Perceived needs of disease vector control programs: A review and synthesis of (sub)national assessments from South Asia and the Middle East

Henk van den Berg, Kabirul Bashar, Rajib Chowdhury, Rajendra M. Bhatt, Hardev Prasad Gupta, Ashwani Kumar, Shanmugavelu Sabesan, Ananganallur N. Shriram, Hari Kishan Raju Konuganti, Akhouri T. S. Sinha, Mohammad Mehdi Sedaghat, Ahmadali Enayati, Hameeda Mohammed Hassan, Aishath Shaheen Najmee, Sana Saleem, Surendra Uranw, Pahalagedera H. D. Kusumawathie, Devika Perera, Mohammed A. Esmail, Lauren B. Carrington, Samira M. Al-Eryani, Roop Kumari, Bhupender N. Nagpal, Sabera Sultana, Raman Velayudhan, Rajpal S. Yadav

Design, development, and validation of multi-epitope proteins for serological diagnosis of Zika virus infections and discrimination from dengue virus seropositivity

Samille Henriques Pereira, Mateus Sá Magalhães Serafim, Thaís de Fátima Silva Moraes, Nathalia Zini, Jônatas Santos Abrahão, Maurício Lacerda Nogueira, Jordana Grazziela Alves Coelho dos Reis, Flávia Fonseca Bagno, Flávio Guimarães da Fonseca

Bayesian modeling of post-vaccination serological data suggests that yearly vaccination of dog aged <2 years old is efficient to stop rabies circulation in Cambodia

Heidi Auerswald, Julia Guillebaud, Benoit Durand, Mathilde Le Vu, Sopheak Sorn, Saraden In, Vutha Pov, Holl Davun, Veasna Duong, Sowath Ly, Philippe Dussart, Véronique Chevalier

Impact of conflict on the elimination targets of lymphatic filariasis, schistosomiasis and soil-transmitted helminths in Cabo Delgado province, Mozambique

Xavier Badia-Rius, Henis Mior Sitoe, Sergio Lopes, Louise A. Kelly-Hope

Leishmania blood parasite dynamics during and after treatment of visceral leishmaniasis in Eastern Africa: A pharmacokinetic-pharmacodynamic model

Luka Verrest, Séverine Monnerat, Ahmed M. Musa, Jane Mbui, Eltahir A. G. Khalil, Joseph Olobo, Monique Wasunna, Wan-Yu Chu, Alwin D. R. Huitema, Henk D. F. H. Schallig, Fabiana Alves, Thomas P. C. Dorlo

Live-attenuated CHIKV vaccine with rearranged genome replicates in vitro and induces immune response in mice

Irina Tretyakova, Joongho Joh, Mary Gearon, Jennifer Kraenzle, Sidney Goedeker, Ava Pignataro, Brian Alejandro, Igor S. Lukashevich, Donghoon Chung, Peter Pushko

Development of a non-infectious control for viral hemorrhagic fever PCR assays

Matthew A. Knox, Collette Bromhead, David TS Hayman

A point-of-care testing assay for clonorchiasis using a EuNPs-CsTR1 fluorescent probe-based immunoassay

Xiaoxiao Ma, Huiyuan Zhang, Yiming Fang, Jing Wang, Xingyang Wang, Chen Li, Xiaolei Liu, Mingyuan Liu, Bin Tang, Yi Liu

Sampling is decisive to determination of Leishmania (Viannia) species

Maxy B. De los Santos, Steev Loyola, Erika S. Perez-Velez, Rocio del Pilar Santos, Ivonne Melissa Ramírez, Hugo O. Valdivia

Spatio-temporal distribution of hospitalizations for chronic Chagas disease and risk factors associated with in-hospital mortality and surgical intervention in Chile

Nicolhole Atero, Marisa Torres, Angélica Domínguez, Benjamín Diethelm-Varela, Francisca Córdova-Bührle, Fernando O. Mardones

Climate-driven models of leptospirosis dynamics in tropical islands from three oceanic basins

Léa Douchet, Christophe Menkes, Vincent Herbreteau, Joséphine Larrieu, Margot Bador, Cyrille Goarant, Morgan Mangeas

Unravelling Chlamydia trachomatis diversity in Amhara, Ethiopia: MLVA-ompA sequencing as a molecular typing tool for trachoma

Anna J. Harte, Ehsan Ghasemian, Harry Pickering, Joanna Houghton, Ambahun Chernet, Eshetu Sata, Gizachew Yismaw, Taye Zeru, Zerihun Tadesse, E. Kelly Callahan, Scott D. Nash, Martin J. Holland

Successful treatment of recurrent visceral leishmaniasis relapse in an immunocompetent adult female with functional hypopituitarism in Bangladesh

Tabiha Binte Hannan, Zazeba Hossain, Utshab Roy, S. M. Mahbubur Rahman, Md Sadiqur Rahman, Sadia Sabah, Md. Abu Rahat, Rajashree Chowdhury, Faria Hossain, Dinesh Mondal, Shampa Saha, Tahniyah Haq, Md Rafiqul Alam, Fazle Rabbi Chowdhury

Phenotypic and functional characteristics of monocyte subsets in the blood and bone marrow of Indian subjects with Visceral Leishmaniasis

Gulafsha Kausar, Shashi Bhushan Chauhan, Ritirupa Roy, Vimal Verma, Sundaram Pandey, Aziza Niyaz, Jaya Chakravarty, Christian R. Engwerda, Susanne Nylen, Rajiv Kumar, Mary E. Wilson, Shyam Sundar

Progress towards elimination of onchocerciasis in the Region du Sud-Ouest of Burkina Faso which was previously subject to a recrudescence event after vector control

Achille Sindimbasba Nikièma, Lassane Koala, Rory J. Post, Appolinaire Kima, Justin Compaoré, Claude M. Kafando, Jean Baptiste Nana, Clarisse Bougouma, Babacar Faye, Soungalo Traoré, Roch Kounbobr Dabiré

Stigma experiences, effects and coping among individuals affected by Buruli ulcer and yaws in Ghana

Ruth Dede Tuwor, Tara B. Mtuy, Yaw Ampem Amoako, Lucy Owusu, Michael Ntiamoah Oppong, Abigail Agbanyo, Bernadette Agbavor, Michael Marks, Stephen L. Walker, Dorothy Yeboah-Manu, Rachel L. Pullan, Jonathan Mensah Dapaah, Richard Odame Phillips, Jennifer Palmer, for the SHARP collaboration

Measuring effects of ivermectin-treated cattle on potential malaria vectors in Vietnam: A cluster-randomized trial

Estee Y. Cramer, Xuan Quang Nguyen, Jeffrey C. Hertz, Do Van Nguyen, Huynh Hong Quang, Ian H. Mendenhall, Andrew A. Lover

Tick species diversity and potential distribution alternation of dominant ticks under different climate scenarios in Xinjiang, China

Rui Ma, Chunfu Li, Ai Gao, Na Jiang, Jian Li, Wei Hu, Xinyu Feng

Behaviour and distribution of Aedes aegypti mosquitoes and their relation to dengue incidence in two transmission hotspots in coastal Ecuador

Leonardo D. Ortega-López, Mauro Pazmiño Betancourth, Renato León, Alain Kohl, Heather M. Ferguson

Projection of dengue fever transmissibility under climate change in South and Southeast Asian countries

Yawen Wang, Conglu Li, Shi Zhao, Yuchen Wei, Kehang Li, Xiaoting Jiang, Janice Ho, Jinjun Ran, Lefei Han, Benny Chung-ying Zee, Ka Chun Chong

Cholera and diarrheal diseases in Cuamba District, Niassa Province, Mozambique: Systematic healthcare facility-based surveillance strengthening, characteristics of suspected cholera and diarrheal patients, and incidence of diarrheal diseases

Cynthia Semá Baltazar, José Paulo Langa, Liliana Dengo Baloi, Jucunu J. Elias Chitio, José Alberto Manuel, Ramos B. J. Mboane, Sadate Assane, Alide Omar, Mariana Manso, Igor Capitine, Naira Luiz, David Mukasa, Geun Hyeog Jang, Ju Yeon Park, Florian Marks, Ramzi Mraidi, Gi Deok Pak, Deok Ryun Kim, Se Eun Park