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July 2022

In Kandal province, a rural area of Cambodia near Phnom Penh, the majority of livestock are raised in backyards. Pigs are kept in open pens next to farmers' houses, and poultry are often free-range in gardens during the day and locked in pens at night. Cattle and dogs are also present, and mosquito density is high. The proximity of competent vectors, pigs, chickens, ducks, and humans could allow year-round circulation of Japanese encephalitis virus, the leading cause of human acute viral encephalitis in Asia. Ladreyt, et al. (2022)

Image Credit: Héléna Ladreyt

Reviews

Mapping the global landscape of chikungunya rapid diagnostic tests: A scoping review

José Moreira, Patrícia Brasil, Sabine Dittrich, André M. Siqueira

Overview of dengue outbreaks in the southwestern Indian Ocean and analysis of factors involved in the shift toward endemicity in Reunion Island: A systematic review

Sarah Hafsia, Marion Haramboure, David Arthur Wilkinson, Thierry Baldet, Luce Yemadje-Menudier, Muriel Vincent, Annelise Tran, Célestine Atyame, Patrick Mavingui

Research Articles

Partial masculinization of Aedes aegypti females by conditional expression of Nix

Bianca B. Kojin, Emma Jakes, James K. Biedler, Zhijian Tu, Zach N. Adelman

Facility-based disease surveillance and Bayesian hierarchical modeling to estimate endemic typhoid fever incidence, Kilimanjaro Region, Tanzania, 2007–2018

Elena R. Cutting, Ryan A. Simmons, Deng B. Madut, Michael J. Maze, Nathaniel H. Kalengo, Manuela Carugati, Ronald M. Mbwasi, Kajiru G. Kilonzo, Furaha Lyamuya, Annette Marandu, Calvin Mosha, Wilbrod Saganda, Bingileki F. Lwezaula, Julian T. Hertz, Anne B. Morrissey, Elizabeth L. Turner, Blandina T. Mmbaga, Grace D. Kinabo, Venance P. Maro, John A. Crump, Matthew P. Rubach

In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution

Gopinath Venugopal, Jordan T. Bird, Charity L. Washam, Hayden Roys, Anne Bowlin, Stephanie D. Byrum, Tiffany Weinkopff

Landscape analysis of NTD diagnostics and considerations on the development of a strategy for regulatory pathways

Hye Lynn Choi, Camilla Ducker, Susie Braniff, Daniel Argaw, Anthony W. Solomon, Bettina Borisch, Deusdedit Mubangizi

Cervical lesion proportion measure using a digital gridded imaging technique to assess cervical pathology in women with genital schistosomiasis

Louise Thomsen Schmidt Arenholt, Katrina Kaestel Aaroe, Kanutte Norderud, Mads Lumholdt, Bodo Sahondra Randrianasolo, Charles Emile Ramarokoto, Oliva Rabozakandraina, Dorthe Broennum, Hermann Feldmeier, Peter Derek Christian Leutscher

Transmission and diversity of Schistosoma haematobium and S. bovis and their freshwater intermediate snail hosts Bulinus globosus and B. nasutus in the Zanzibar Archipelago, United Republic of Tanzania

Tom Pennance, Shaali Makame Ame, Amour Khamis Amour, Khamis Rashid Suleiman, Mtumweni Ali Muhsin, Fatma Kabole, Said Mohammed Ali, John Archer, Fiona Allan, Aidan Emery, Muriel Rabone, Stefanie Knopp, David Rollinson, Joanne Cable, Bonnie L. Webster

The epidemiology and disease burden of children hospitalized for viral infections within the family Flaviviridae in China: A national cross-sectional study

Ran Wang, Xinyu Wang, Linlin Zhang, Guoshuang Feng, Mengjia Liu, Yueping Zeng, Zhengde Xie

Zika virus persistence in the male macaque reproductive tract

Erin E. Ball, Patricia A. Pesavento, Koen K. A. Van Rompay, M. Kevin Keel, Anil Singapuri, Jose P. Gomez-Vazquez, Dawn M. Dudley, David H. O’Connor, Meghan E. Breitbach, Nicholas J. Maness, Blake Schouest, Antonito Panganiban, Lark L. Coffey

Zika virus-like particle vaccine fusion loop mutation increases production yield but fails to protect AG129 mice against Zika virus challenge

Danielle Thompson, Ben Guenther, Darly Manayani, Jason Mendy, Jonathan Smith, Diego A. Espinosa, Eva Harris, Jeff Alexander, Lo Vang, Christopher S. Morello

“Then they prayed, they did nothing else, they just prayed for the boy and he was well”: A qualitative investigation into the perceptions and behaviours surrounding snakebite and its management in rural communities of Kitui county, Kenya

Leo Wood, Cecilia Ngari, Stanley Parkurito, Kieran Barnes, Denis Otundo, Daniel Asiago Misiani, Geoffrey Maranga Kephah, Anna Trelfa, George O. Olouch, Robert A. Harrison, Frank-Leonel Tianyi

A scoping review of burden of disease studies estimating disability-adjusted life years due to Taenia solium

Andrew Larkins, Mieghan Bruce, Carlotta Di Bari, Brecht Devleesschauwer, David M. Pigott, Amanda Ash

City puzzles: Does urban land scape affect genetic population structure in Aedes aegypti?

Lucía Maffey, Viviana Confalonieri, Esteban Hasson, Nicolás Schweigmann

First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017

Athanase Badolo, Aboubacar Sombié, Félix Yaméogo, Dimitri W. Wangrawa, Aboubakar Sanon, Patricia M. Pignatelli, Antoine Sanon, Mafalda Viana, Hirotaka Kanuka, David Weetman, Philip J. McCall

The economic evaluation of Cystic echinococcosis control strategies focused on zoonotic hosts: A scoping review

Jo Widdicombe, María-Gloria Basáñez, Mahbod Entezami, Daniel Jackson, Edmundo Larrieu, Joaquín M. Prada

RNA as a feasible marker of Trypanosoma cruzi viability during the parasite interaction with the triatomine vector Rhodnius prolixus (Hemiptera, Triatominae)

Paula Finamore-Araujo, Gabriel Lucio Silva da Fonseca, Cecília Stahl Vieira, Daniele Pereira de Castro, Otacilio Cruz Moreira

Heterogeneity in dog population characteristics contributes to chronic under-vaccination against rabies in Guatemala

David Moran, Danilo Alvarez, Loren Cadena, Julie Cleaton, Stephanie J. Salyer, Emily G. Pieracci, Leila R. Camposeco, Sulma Bernal, Ryan M. Wallace

Efficacy of intra-lesional injections of meglumine antimoniate once a week vs. twice a week in the treatment of cutaneous leishmaniasis caused by L. tropica in Iran: A randomized controlled clinical trial

Amir Javadi, Ali Khamesipour, Mohammad Ghoorchi, Mahdieh Bahrami, Alireza Khatami, Iraj Sharifi, Seyed Ebrahim Eskandari, Alireza Fekri, Mohamad Reza Aflatoonian, Alireza Firooz

An ecological niche model to predict the geographic distribution of Haemagogus janthinomys, Dyar, 1921 a yellow fever and Mayaro virus vector, in South America

Michael Celone, David Brooks Pecor, Alexander Potter, Alec Richardson, James Dunford, Simon Pollett

Absence of lower genital tract lesions among women of reproductive age infected with Schistosoma mansoni: A cross-sectional study using a colposcope in Western Kenya

Huldah C. Sang, Pauline N. M. Mwinzi, Maurice R. Odiere, Isaac Onkanga, Fredrick Rawago, Pavitra Pillay, Eyrun Floerecke Kjetland

A participatory epidemiological and One Health approach to explore the community’s capacity to detect emerging zoonoses and surveillance network opportunities in the forest region of Guinea

Marie-Jeanne Guenin, Hélène Marie De Nys, Marisa Peyre, Etienne Loire, Suporn Thongyuan, Abdoulaye Diallo, Léonce Zogbelemou, Flavie Luce Goutard

Forecasting the elimination of active trachoma: An empirical model

Kristen K. Renneker, Paul M. Emerson, P. J. Hooper, Jeremiah M. Ngondi

Estimating dengue transmission intensity from serological data: A comparative analysis using mixture and catalytic models

Victoria Cox, Megan O’Driscoll, Natsuko Imai, Ari Prayitno, Sri Rezeki Hadinegoro, Anne-Frieda Taurel, Laurent Coudeville, Ilaria Dorigatti

Modelling to infer the role of animals in gambiense human African trypanosomiasis transmission and elimination in the DRC

Ronald E. Crump, Ching-I Huang, Simon E. F. Spencer, Paul E. Brown, Chansy Shampa, Erick Mwamba Miaka, Kat S. Rock

Modelling Japanese encephalitis virus transmission dynamics and human exposure in a Cambodian rural multi-host system

Héléna Ladreyt, Véronique Chevalier, Benoit Durand

Historical overview and geographical distribution of neglected tropical diseases amenable to preventive chemotherapy in the Republic of the Congo: A systematic review

Joseph A. Ngatse, Gilbert Ndziessi, François Missamou, Rodrigue Kinouani, Marlhand Hemilembolo, Sébastien D. Pion, Kirsten A. Bork, Ange A. Abena, Michel Boussinesq, Cédric B. Chesnais

Identification of a linear B-cell epitope on the Schistosoma japonicum saposin protein, SjSAP4: Potential as a component of a multi-epitope diagnostic assay

Yi Mu, Catherine A. Gordon, Remigio M. Olveda, Allen G. Ross, David U. Olveda, Jessica M. Marsh, Donald P. McManus, Pengfei Cai

Estimating the genetic structure of Triatoma dimidiata (Hemiptera: Reduviidae) and the transmission dynamics of Trypanosoma cruzi in Boyacá, eastern Colombia

Natalia Velásquez-Ortiz, Carolina Hernández, Omar Cantillo-Barraza, Manuel Medina, Mabel Medina-Alfonso, Sandra Suescún-Carrero, Marina Muñoz, Laura Vega, Sergio Castañeda, Lissa Cruz-Saavedra, Nathalia Ballesteros, Juan David Ramírez

Risk of seroconversion and seroreversion of antibodies to Chlamydia trachomatis pgp3 in a longitudinal cohort of children in a low trachoma prevalence district in Tanzania

Xinyi Chen, Beatriz Munoz, Harran Mkocha, Charlotte A. Gaydos, Laura Dize, Thomas C. Quinn, Sheila K. West

Susceptibility status of the wild-caught Phlebotomus argentipes (Diptera: Psychodidae: Phlebotominae), the sand fly vector of visceral leishmaniasis, to different insecticides in Nepal

Lalita Roy, Surendra Uranw, Kristien Cloots, Tom Smekens, Usha Kiran, Uttam Raj Pyakurel, Murari Lal Das, Rajpal S. Yadav, Wim Van Bortel

The burden of T. solium cysticercosis and selected neuropsychiatric disorders in Mocuba district, Zambézia province, Mozambique

Irene Langa, Fernando Padama, Noémia Nhancupe, Alberto Pondja, Delfina Hlashwayo, Lidia Gouveia, Dominik Stelzle, Clarissa Prazeres da Costa, Veronika Schmidt, Andrea S. Winkler, Emília Virgínia Noormahomed

Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection

Joseph Bertin Kadji Fassi, Hermine Boukeng Jatsa, Ulrich Membe Femoe, Valentin Greigert, Julie Brunet, Catherine Cannet, Christian Mérimé Kenfack, Nestor Gipwe Feussom, Emilienne Tienga Nkondo, Ahmed Abou-Bacar, Alexander Wilhelm Pfaff, René Kamgang, Pierre Kamtchouing, Louis-Albert Tchuem Tchuenté

Examination of the independent contribution of rheumatic heart disease and congestive cardiac failure to the development and outcome of melioidosis in Far North Queensland, tropical Australia

Phoebe Davies, Simon Smith, Rob Wilcox, James D. Stewart, Tania J. Davis, Kylie McKenna, Josh Hanson

Cryptogenic hepatitis patients have a higher Bartonella sp.-DNA detection in blood and skin samples than patients with non-viral hepatitis of known cause

Marina Rovani Drummond, Luciene Silva dos Santos, Renata Soalheiro Fávaro, Raquel Silveira Bello Stucchi, Ilka de Fátima Santana Ferreira Boin, Paulo Eduardo Neves Ferreira Velho

Prevalence of simian malaria among macaques in Malaysia (2000–2021): A systematic review

Janeeca Sam, Nadia Aqilla Shamsusah, Amatul Hamizah Ali, Rozita Hod, Mohd Rohaizat Hassan, Hani Kartini Agustar

SARS-CoV-2 seropositivity and COVID-19 among 5 years-old Amazonian children and their association with poverty and food insecurity

Marcelo U. Ferreira, Isabel Giacomini, Priscila M. Sato, Barbara H. Lourenço, Vanessa C. Nicolete, Lewis F. Buss, Alicia Matijasevich, Marcia C. Castro, Marly A. Cardoso, for the MINA-Brazil Working Group

Vector competence and immune response of Aedes aegypti for Ebinur Lake virus, a newly classified mosquito-borne orthobunyavirus

Cihan Yang, Fei Wang, Doudou Huang, Haixia Ma, Lu Zhao, Guilin Zhang, Hailong Li, Qian Han, Dennis Bente, Ferdinand Villanueva Salazar, Zhiming Yuan, Han Xia

2-Deoxy-D-glucose and combined 2-Deoxy-D-glucose/albendazole exhibit therapeutic efficacy against Echinococcus granulosus protoscoleces and experimental alveolar echinococcosis

Qi Xin, Wei Lv, Yunxi Xu, Yumei Luo, Caifang Zhao, Bichen Wang, Miaomiao Yuan, Huanping Li, Xiaoxia Song, Tao Jing

Geospatial modeling of pre-intervention nodule prevalence of Onchocerca volvulus in Ethiopia as an aid to onchocerciasis elimination

Himal Shrestha, Karen McCulloch, Shannon M. Hedtke, Warwick N. Grant

Clinical, epidemiological, and spatial features of human rabies cases in Metro Manila, the Philippines from 2006 to 2015

Ferdinand D. Guzman, Yuta Iwamoto, Nobuo Saito, Eumelia P. Salva, Efren M. Dimaano, Akira Nishizono, Motoi Suzuki, Oladeji Oloko, Koya Ariyoshi, Chris Smith, Christopher M. Parry, Rontgene M. Solante

Linear and Machine Learning modelling for spatiotemporal disease predictions: Force-of-Infection of Chagas disease

Julia Ledien, Zulma M. Cucunubá, Gabriel Parra-Henao, Eliana Rodríguez-Monguí, Andrew P. Dobson, Susana B. Adamo, María-Gloria Basáñez, Pierre Nouvellet

Comparing sources of mobility for modelling the epidemic spread of Zika virus in Colombia

Daniela Perrotta, Enrique Frias-Martinez, Ana Pastore y Piontti, Qian Zhang, Miguel Luengo-Oroz, Daniela Paolotti, Michele Tizzoni, Alessandro Vespignani

Seroprevalence of Strongyloides stercoralis infection in a South Indian adult population

Saravanan Munisankar, Anuradha Rajamanickam, Suganthi Balasubramanian, Satishwaran Muthusamy, Chandra Kumar Dolla, Pradeep Aravindan Menon, Ponnuraja Chinnayan, Christopher Whalen, Paschaline Gumne, Inderdeep Kaur, Varma Nadimpalli, Akshay Deverakonda, Zhenhao Chen, John David Otto, Tesfalidet Habitegiyorgis, Harish Kandaswamy, Thomas B. Nutman, Subash Babu

Step towards elimination of Wuchereria bancrofti in Southwest Tanzania 10 years after mass drug administration with Albendazole and Ivermectin

Jonathan Mnkai, Thomas F. Marandu, Jacklina Mhidze, Agatha Urio, Lucas Maganga, Antelmo Haule, Godfrey Kavishe, Elizabeth Ntapara, Nhamo Chiwerengo, Petra Clowes, Sacha Horn, Maureen Mosoba, Wilfred Lazarus, Abdallah Ngenya, Akili Kalinga, Alex Debrah, Friedrich Rieß, Elmar Saathoff, Christof Geldmacher, Achim Hoerauf, Michael Hoelscher, Mkunde Chachage, Inge Kroidl

Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease

Graham L. Cromar, Jonathan R. Epp, Ana Popovic, Yusing Gu, Violet Ha, Brandon J. Walters, James St. Pierre, Xuejian Xiong, John G. Howland, Sheena A. Josselyn, Paul W. Frankland, John Parkinson

Epidemiology of yellow fever virus in humans, arthropods, and non-human primates in sub-Saharan Africa: A systematic review and meta-analysis

Martin Gael Oyono, Sebastien Kenmoe, Ngu Njei Abanda, Guy Roussel Takuissu, Jean Thierry Ebogo-Belobo, Raoul Kenfack-Momo, Cyprien Kengne-Nde, Donatien Serge Mbaga, Serges Tchatchouang, Josiane Kenfack-Zanguim, Robertine Lontuo Fogang, Elisabeth Zeuko’o Menkem, Juliette Laure Ndzie Ondigui, Ginette Irma Kame-Ngasse, Jeannette Nina Magoudjou-Pekam, Arnol Bowo-Ngandji, Seraphine Nkie Esemu, Lucy Ndip

Hypnozoite depletion in successive Plasmodium vivax relapses

Rintis Noviyanti, Kelly Carey-Ewend, Leily Trianty, Christian Parobek, Agatha Mia Puspitasari, Sujata Balasubramanian, Zackary Park, Nicholas Hathaway, Retno A. S. Utami, Saraswati Soebianto, Jeny Jeny, Frilasita Yudhaputri, Aditya Perkasa, Farah N. Coutrier, Yusrifar K. Tirta, Lenny Ekawati, Bagus Tjahyono, Inge Sutanto, Erni J. Nelwan, Herawati Sudoyo, J. Kevin Baird, Jessica T. Lin

Regulatory T cells in erythema nodosum leprosum maintain anti-inflammatory function

Edessa Negera, Kidist Bobosha, Abraham Aseffa, Hazel M. Dockrell, Diana N. J. Lockwood, Stephen L. Walker

Associated factors of the co-occurrence of trachoma and soil-transmitted helminthiases in children 1 to 9 years old in rural communities of the Amazon basin in Loreto Department, Peru: Results from a population-based survey

Martha Idalí Saboyá-Díaz, Cristiam Armando Carey Angeles, Rosario del Socorro Avellaneda Yajahuanca, Salvith Karen Meléndez Ruíz, Rufino Cabrera, Harvy Alberto Honorio Morales, Paul E. Pachas, Monica Guardo, Kristen K. Renneker, Beatriz E. Muñoz, Sheila K. West

Systematic whole-genome sequencing reveals an unexpected diversity among actinomycetoma pathogens and provides insights into their antibacterial susceptibilities

Andrew Keith Watson, Bernhard Kepplinger, Sahar Mubarak Bakhiet, Najwa Adam Mhmoud, Jonathan Chapman, Nick EE Allenby, Katarzyna Mickiewicz, Michael Goodfellow, Ahmed Hassan Fahal, Jeff Errington

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