Precision mapping: An innovative tool and way forward to shrink the map, better target interventions, and accelerate toward the elimination of schistosomiasis

Louis-Albert Tchuem Tchuenté, J. Russell Stothard, David Rollinson, Jutta Reinhard-Rupp

PLOS Neglected Tropical Diseases: published August 2, 2018 | https://doi.org/10.1371/journal.pntd.0006563

The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases

Joanna M. Bridger, Paul J. Brindley, Matty Knight

PLOS Neglected Tropical Diseases: published August 9, 2018 | https://doi.org/10.1371/journal.pntd.0006552

Hajj, Umrah, and the neglected tropical diseases

Mashal M. Almutairi, Waleed Saleh Alsalem, Mazen Hassanain, Peter J. Hotez

PLOS Neglected Tropical Diseases: published August 16, 2018 | https://doi.org/10.1371/journal.pntd.0006539

The diverse roles of cysteine proteases in parasites and their suitability as drug targets

James H. McKerrow

PLOS Neglected Tropical Diseases: published August 23, 2018 | https://doi.org/10.1371/journal.pntd.0005639

Update on drug development targeting parasite cysteine proteases

James H. McKerrow

PLOS Neglected Tropical Diseases: published August 23, 2018 | https://doi.org/10.1371/journal.pntd.0005850

Toward the 2020 goal of soil-transmitted helminthiasis control and elimination

Sören L. Becker, Harvy Joy Liwanag, Jedidiah S. Snyder, Oladele Akogun, Vicente Belizario. Jr, Matthew C. Freeman, Theresa W. Gyorkos, Rubina Imtiaz, Jennifer Keiser, Alejandro Krolewiecki, Bruno Levecke, Charles Mwandawiro, Rachel L. Pullan, David G. Addiss, Jürg Utzinger

PLOS Neglected Tropical Diseases: published August 14, 2018 | https://doi.org/10.1371/journal.pntd.0006606

Rapid, inexpensive, fingerstick, whole-blood, sensitive, specific, point-of-care test for anti-Toxoplasma antibodies

Joseph Lykins, Xuan Li, Pauline Levigne, Ying Zhou, Kamal El Bissati, Fatima Clouser, Martine Wallon, Florence Morel, Karen Leahy, Bouchra El Mansouri, Maryam Siddiqui, Nicole Leong, Morgan Michalowski, Erin Irwin, Perpetua Goodall, Mahmoud Ismail, Monica Christmas, El Bachir Adlaoui, Mohamed Rhajaoui, Amina Barkat, Hua Cong, Ian J. Begeman, Bo Shiun Lai, Despina G. Contopoulos-Ioannidis, Jose G. Montoya, Yvonne Maldonado, Raymund Ramirez, Cindy Press, Francois Peyron, Rima McLeod

PLOS Neglected Tropical Diseases: published August 16, 2018 | https://doi.org/10.1371/journal.pntd.0006536

Potential novel tick-borne Colpodella species parasite infection in patient with neurological symptoms

Jia-Fu Jiang, Rui-Ruo Jiang, Qiao-Cheng Chang, Yuan-Chun Zheng, Bao-Gui Jiang, Yi Sun, Na Jia, Ran Wei, Hong-Bo Liu, Qiu-Bo Huo, Hong Wang, Michael E. von Fricken, Wu-Chun Cao

PLOS Neglected Tropical Diseases: published August 2, 2018 | https://doi.org/10.1371/journal.pntd.0006546

Cysteine proteases as digestive enzymes in parasitic helminths

Conor R. Caffrey, Louise Goupil, Karina M. Rebello, John P. Dalton, David Smith

PLOS Neglected Tropical Diseases: published August 23, 2018 | https://doi.org/10.1371/journal.pntd.0005840

Cysteine proteases during larval migration and development of helminths in their final host

Alexandra Grote, Conor R. Caffrey, Karina M. Rebello, David Smith, John P. Dalton, Sara Lustigman

PLOS Neglected Tropical Diseases: published August 23, 2018 | https://doi.org/10.1371/journal.pntd.0005919

Cysteine proteases in protozoan parasites

Jair L. Siqueira-Neto, Anjan Debnath, Laura-Isobel McCall, Jean A. Bernatchez, Momar Ndao, Sharon L. Reed, Philip J. Rosenthal

PLOS Neglected Tropical Diseases: published August 23, 2018 | https://doi.org/10.1371/journal.pntd.0006512

MyD88 activation in cardiomyocytes contributes to the heart immune response to acute Trypanosoma cruzi infection with no effect on local parasite control

Danni Yohani Santana, Rafael Moysés Salgado, Marina Fevereiro, Rogério Silva do Nascimento, Raissa Fonseca, Niels Olsen Saraiva Câmara, Sabrina Epiphanio, Cláudio Romero Farias Marinho, Maria Luiza Barreto-Chaves, Maria Regina D’ Império-Lima, José M. Álvarez

PLOS Neglected Tropical Diseases: published August 1, 2018 | https://doi.org/10.1371/journal.pntd.0006617

The importance of dog population contact network structures in rabies transmission

Mirjam Laager, Céline Mbilo, Enos Abdelaziz Madaye, Abakar Naminou, Monique Léchenne, Aurélie Tschopp, Service Kemdongarti Naïssengar, Timo Smieszek, Jakob Zinsstag, Nakul Chitnis

PLOS Neglected Tropical Diseases: published August 1, 2018 | https://doi.org/10.1371/journal.pntd.0006680

The impact of the Ebola virus disease (EVD) epidemic on agricultural production and livelihoods in Liberia

Tsegaye T. Gatiso, Isabel Ordaz-Németh, Trokon Grimes, Menladi Lormie, Clement Tweh, Hjalmar S. Kühl, Jessica Junker

PLOS Neglected Tropical Diseases: published August 2, 2018 | https://doi.org/10.1371/journal.pntd.0006580

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PLOS Neglected Tropical Diseases: published August 2, 2018 | https://doi.org/10.1371/journal.pntd.0006607

Simulation of population dynamics of Bulinus globosus: Effects of environmental temperature on production of Schistosoma haematobium cercariae

Chester Kalinda, Moses J. Chimbari, William E. Grant, Hsiao-Hsuan Wang, Julius N. Odhiambo, Samson Mukaratirwa

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Cs1, a Clonorchis sinensis-derived serodiagnostic antigen containing tandem repeats and a signal peptide

Na Cheng, Xue-Nian Xu, Yan Zhou, Yu-Ting Dong, Yi-Fang Bao, Bin Xu, Wei Hu, Zheng Feng

PLOS Neglected Tropical Diseases: published August 2, 2018 | https://doi.org/10.1371/journal.pntd.0006683

Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model

Erin M. McDonald, Nisha K. Duggal, Jana M. Ritter, Aaron C. Brault

PLOS Neglected Tropical Diseases: published August 2, 2018 | https://doi.org/10.1371/journal.pntd.0006691

Immunomodulatory drug methotrexate used to treat patients with chronic inflammatory rheumatisms post-chikungunya does not impair the synovial antiviral and bone repair responses

Yosra Bedoui, Claude Giry, Marie-Christine Jaffar-Bandjee, Jimmy Selambarom, Pascale Guiraud, Philippe Gasque

PLOS Neglected Tropical Diseases: published August 3, 2018 | https://doi.org/10.1371/journal.pntd.0006634

A systematic review of hepatitis B virus (HBV) drug and vaccine escape mutations in Africa: A call for urgent action

Jolynne Mokaya, Anna L. McNaughton, Martin J. Hadley, Apostolos Beloukas, Anna-Maria Geretti, Dominique Goedhals, Philippa C. Matthews

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006629

Estimating dengue under-reporting in Puerto Rico using a multiplier model

Manjunath B. Shankar, Rosa L. Rodríguez-Acosta, Tyler M. Sharp, Kay M. Tomashek, Harold S. Margolis, Martin I. Meltzer

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006650

Stratified sero-prevalence revealed overall high disease burden of dengue but suboptimal immunity in younger age groups in Pune, India

Akhilesh C. Mishra, Vidya A. Arankalle, Swapnil A. Gadhave, Pritam H. Mahadik, Shubham Shrivastava, Mandar Bhutkar, Varsha M. Vaidya

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006657

Schistosoma haematobium effects on Plasmodium falciparum infection modified by soil-transmitted helminths in school-age children living in rural areas of Gabon

Jean Claude Dejon-Agobé, Jeannot Fréjus Zinsou, Yabo Josiane Honkpehedji, Ulysse Ateba-Ngoa, Jean-Ronald Edoa, Bayodé Roméo Adegbite, Ghyslain Mombo-Ngoma, Selidji Todagbe Agnandji, Michael Ramharter, Peter Gottfried Kremsner, Bertrand Lell, Martin Peter Grobusch, Ayôla Akim Adegnika

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006663

Screening of the Pathogen Box for inhibitors with dual efficacy against Giardia lamblia and Cryptosporidium parvum

Kelly M. Hennessey, Ilse C. Rogiers, Han-Wei Shih, Matthew A. Hulverson, Ryan Choi, Molly C. McCloskey, Grant R. Whitman, Lynn K. Barrett, Ethan A. Merritt, Alexander R. Paredez, Kayode K. Ojo

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006673

An exploratory study on rabies exposure through contact tracing in a rural area near Bengaluru, Karnataka, India

N. R. Ramesh Masthi, Pruthvi S.

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006682

Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles

Sunamita de Carvalho Lima, Lucas de Carvalho Porta, Álvaro da Costa Lima, Joana D’Arc Campeiro, Ywlliane Meurer, Nathália Bernardes Teixeira, Thiago Duarte, Eduardo Brandt Oliveira, Gisele Picolo, Rosely Oliveira Godinho, Regina Helena Silva, Mirian Akemi Furuie Hayashi

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006700

Improving clinical and epidemiological predictors of Buruli ulcer

Gilbert Adjimon Ayelo, Ghislain Emmanuel Sopoh, Jean-Gabin Houezo, René Fiodessihoue, Dissou Affolabi, Ange Dodji Dossou, Yves Thierry Barogui, Akpeedje Anita Carolle Wadagni, Didier Codjo Agossadou, Epco Hasker, Françoise Portaels, Bouke C. de Jong, Miriam Eddyani

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006713

Epidemiology and antimicrobial resistance of invasive non-typhoidal Salmonellosis in rural Thailand from 2006-2014

Toni Whistler, Patranuch Sapchookul, David W. McCormick, Ornuma Sangwichian, Possawat Jorakate, Sirirat Makprasert, Anchalee Jatapai, Sathapana Naorat, Uraiwan Surin, Surathinee Koosakunwat, Surachai Supcharassaeng, Barameht Piralam, Mathew Mikoleit, Henry C. Baggett, Julia Rhodes, Christopher J. Gregory

PLOS Neglected Tropical Diseases: published August 6, 2018 | https://doi.org/10.1371/journal.pntd.0006718

Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS)

Odin Goovaerts, Pauline N. M. Mwinzi, Erick M. O. Muok, Ann Ceulemans, Robert Colebunders, Luc Kestens

PLOS Neglected Tropical Diseases: published August 8, 2018 | https://doi.org/10.1371/journal.pntd.0006710

Dynamic changes in human-gut microbiome in relation to a placebo-controlled anthelminthic trial in Indonesia

Ivonne Martin, Yenny Djuardi, Erliyani Sartono, Bruce A. Rosa, Taniawati Supali, Makedonka Mitreva, Jeanine J. Houwing-Duistermaat, Maria Yazdanbakhsh

PLOS Neglected Tropical Diseases: published August 9, 2018 | https://doi.org/10.1371/journal.pntd.0006620

Blockade of dengue virus entry into myeloid cells by endocytic inhibitors in the presence or absence of antibodies

Ana C. Carro, Luana E. Piccini, Elsa B. Damonte

PLOS Neglected Tropical Diseases: published August 9, 2018 | https://doi.org/10.1371/journal.pntd.0006685

Patients with cystic echinococcosis in the three national referral centers of Mongolia: A model for CE management assessment

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PLOS Neglected Tropical Diseases: published August 9, 2018 | https://doi.org/10.1371/journal.pntd.0006686

Is the priority review voucher program stimulating new drug development for tropical diseases?

Kirk W. Kerr, Thomas C. Henry, Kathleen L. Miller

PLOS Neglected Tropical Diseases: published August 9, 2018 | https://doi.org/10.1371/journal.pntd.0006695

Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy

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PLOS Neglected Tropical Diseases: published August 9, 2018 | https://doi.org/10.1371/journal.pntd.0006705

Campylobacter, a zoonotic pathogen of global importance: Prevalence and risk factors in the fast-evolving chicken meat system of Nairobi, Kenya

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PLOS Neglected Tropical Diseases: published August 13, 2018 | https://doi.org/10.1371/journal.pntd.0006658

Low incidence of recurrent Buruli ulcers in treated Australian patients living in an endemic region

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PLOS Neglected Tropical Diseases: published August 13, 2018 | https://doi.org/10.1371/journal.pntd.0006724

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

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PLOS Neglected Tropical Diseases: published August 13, 2018 | https://doi.org/10.1371/journal.pntd.0006728

Trypanosoma brucei triggers a marked immune response in male reproductive organs

Tânia Carvalho, Sandra Trindade, Sílvia Pimenta, Ana B. Santos, Filipa Rijo-Ferreira, Luísa M. Figueiredo

PLOS Neglected Tropical Diseases: published August 15, 2018 | https://doi.org/10.1371/journal.pntd.0006690

The effect of temperature increase on the development of Rhodnius prolixus and the course of Trypanosoma cruzi metacyclogenesis

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PLOS Neglected Tropical Diseases: published August 15, 2018 | https://doi.org/10.1371/journal.pntd.0006735

Human plague associated with Tibetan sheep originates in marmots

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PLOS Neglected Tropical Diseases: published August 16, 2018 | https://doi.org/10.1371/journal.pntd.0006635

Effectiveness of Lonomia antivenom in recovery from the coagulopathy induced by Lonomia orientoandensis and Lonomia casanarensis caterpillars in rats

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Sphingosine-1-phosphate signaling in Leishmania donovani infection in macrophages

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Population genomics of Culiseta melanura, the principal vector of Eastern equine encephalitis virus in the United States

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PLOS Neglected Tropical Diseases: published August 17, 2018 | https://doi.org/10.1371/journal.pntd.0006698

North American Culex pipiens and Culex quinquefasciatus are competent vectors for Usutu virus

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Spatiotemporal prediction of infectious diseases using structured Gaussian processes with application to Crimean–Congo hemorrhagic fever

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PLOS Neglected Tropical Diseases: published August 17, 2018 | https://doi.org/10.1371/journal.pntd.0006737

Impact of community-based integrated mass drug administration on schistosomiasis and soil-transmitted helminth prevalence in Togo

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Risk factors for diagnosed noma in northwest Nigeria: A case-control study, 2017

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Comparison of the dynamics of Japanese encephalitis virus circulation in sentinel pigs between a rural and a peri-urban setting in Cambodia

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PLOS Neglected Tropical Diseases: published August 23, 2018 | https://doi.org/10.1371/journal.pntd.0006644

Field-collected Triatoma sordida from central Brazil display high microbiota diversity that varies with regard to developmental stage and intestinal segmentation

Joana L. Oliveira, Juliano C. Cury, Rodrigo Gurgel-Gonçalves, Ana C. Bahia, Fernando A. Monteiro

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Evidence for transovarial transmission of tick-borne rickettsiae circulating in Northern Mongolia

Thomas C. Moore, Laura A. Pulscher, Luke Caddell, Michael E. von Fricken, Benjamin D. Anderson, Battsetseg Gonchigoo, Gregory C. Gray

PLOS Neglected Tropical Diseases: published August 27, 2018 | https://doi.org/10.1371/journal.pntd.0006696

Community-directed vector control to supplement mass drug distribution for onchocerciasis elimination in the Madi mid-North focus of Northern Uganda

Benjamin G. Jacob, Denis Loum, Thomson L. Lakwo, Charles R. Katholi, Peace Habomugisha, Edson Byamukama, Edridah Tukahebwa, Eddie W. Cupp, Thomas R. Unnasch

PLOS Neglected Tropical Diseases: published August 27, 2018 | https://doi.org/10.1371/journal.pntd.0006702

Spinal cord hypometabolism associated with infection by human T-cell lymphotropic virus type 1(HTLV-1)

Luiz C. F. Romanelli, Débora M. Miranda, Anna B. F. Carneiro-Proietti, Marcelo Mamede, Herika M. M. Vasconcelos, Marina L Martins, Anísia S. D. Ferreira, Daniela V. F. Rosa, Jonas J. Paula, Marco A. Romano-Silva, Rodrigo Nicolato

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