Homes of Southwest Pacific coastal villages characteristically line the beach. Malaria vectors are found within a kilometer of the coast and Plasmodium vivax is common. A population genetic survey of P. vivax across the Southwest Pacific, where malaria transmission declines from west to east, revealed an association between transmission, the degree of inbreeding and population structure. Within Solomon Islands, parasites were structured at different spatial scales, and diversity declined over an eight-year period of malaria control. Genetic surveillance is thus a useful tool for monitoring the impact of control efforts on P. vivax populations and will provide important guidance for targeted interventions. Waltmann et al.
Image Credit: Andreea Waltmann
Editorial
PLOS NTDs celebrates our 10th anniversary: Looking forward to the next decade
PLOS Neglected Tropical Diseases: published January 25, 2018 | https://doi.org/10.1371/journal.pntd.0006176
Viewpoints
Madagascar can build stronger health systems to fight plague and prevent the next epidemic
PLOS Neglected Tropical Diseases: published January 4, 2018 | https://doi.org/10.1371/journal.pntd.0006131
Historical Profiles and Perspectives
Historical perspective: Revisiting the St. Lucia Project, a multi-year comparison trial of schistosomiasis control strategies
PLOS Neglected Tropical Diseases: published January 31, 2018 | https://doi.org/10.1371/journal.pntd.0006223
Reviews
Histoplasmosis in Africa: An emerging or a neglected disease?
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006046
The rise of neglected tropical diseases in the "new Texas"
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0005581
Canine visceral leishmaniasis: Diagnosis and management of the reservoir living among us
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0006082
Research Articles
Rapid autophagic regression of the milk gland during involution is critical for maximizing tsetse viviparous reproductive output
PLOS Neglected Tropical Diseases: published January 31, 2018 | https://doi.org/10.1371/journal.pntd.0006204
High prevalence of S. Stercoralis infection among patients with Chagas disease: A retrospective case-control study
PLOS Neglected Tropical Diseases: published January 31, 2018 | https://doi.org/10.1371/journal.pntd.0006199
Rhinoscleroma pathogenesis: The type K3 capsule of Klebsiella rhinoscleromatis is a virulence factor not involved in Mikulicz cells formation
PLOS Neglected Tropical Diseases: published January 30, 2018 | https://doi.org/10.1371/journal.pntd.0006201
Mycobacterium leprae genomes from naturally infected nonhuman primates
PLOS Neglected Tropical Diseases: published January 30, 2018 | https://doi.org/10.1371/journal.pntd.0006190
Trypanosoma cruzi vaccine candidate antigens Tc24 and TSA-1 recall memory immune response associated with HLA-A and -B supertypes in Chagasic chronic patients from Mexico
PLOS Neglected Tropical Diseases: published January 29, 2018 | https://doi.org/10.1371/journal.pntd.0006240
Estimating Cryptosporidium and Giardia disease burdens for children drinking untreated groundwater in a rural population in India
PLOS Neglected Tropical Diseases: published January 29, 2018 | https://doi.org/10.1371/journal.pntd.0006231
Caregivers’ views on stigmatization and discrimination of people affected by leprosy in Ghana
PLOS Neglected Tropical Diseases: published January 29, 2018 | https://doi.org/10.1371/journal.pntd.0006219
Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs
PLOS Neglected Tropical Diseases: published January 29, 2018 | https://doi.org/10.1371/journal.pntd.0006218
Molecular epidemiology of dengue viruses in three provinces of Lao PDR, 2006-2010
PLOS Neglected Tropical Diseases: published January 29, 2018 | https://doi.org/10.1371/journal.pntd.0006203
Dried Blood Spots for Measuring Vibrio cholerae-specific Immune Responses
PLOS Neglected Tropical Diseases: published January 29, 2018 | https://doi.org/10.1371/journal.pntd.0006196
Diagnostic metabolite biomarkers of chronic typhoid carriage
PLOS Neglected Tropical Diseases: published January 26, 2018 | https://doi.org/10.1371/journal.pntd.0006215
Schistosoma mansoni infection suppresses the growth of Plasmodium yoelii parasites in the liver and reduces gametocyte infectivity to mosquitoes
PLOS Neglected Tropical Diseases: published January 26, 2018 | https://doi.org/10.1371/journal.pntd.0006197
Increasingly inbred and fragmented populations of Plasmodium vivax associated with the eastward decline in malaria transmission across the Southwest Pacific
PLOS Neglected Tropical Diseases: published January 26, 2018 | https://doi.org/10.1371/journal.pntd.0006146
Interventions to maximize facial cleanliness and achieve environmental improvement for trachoma elimination: A review of the grey literature
PLOS Neglected Tropical Diseases: published January 25, 2018 | https://doi.org/10.1371/journal.pntd.0006178
Emerging trends of Zika apprehension in an epidemic setting
PLOS Neglected Tropical Diseases: published January 25, 2018 | https://doi.org/10.1371/journal.pntd.0006167
Expanding molecular diagnostics of helminthiasis: Piloting use of the GPLN platform for surveillance of soil transmitted helminthiasis and schistosomiasis in Ghana
PLOS Neglected Tropical Diseases: published January 25, 2018 | https://doi.org/10.1371/journal.pntd.0006129
Quantitative and histological assessment of maternal-fetal transmission of Trypanosoma cruzi in guinea pigs: An experimental model of congenital Chagas disease
PLOS Neglected Tropical Diseases: published January 24, 2018 | https://doi.org/10.1371/journal.pntd.0006222
Serum metabolome changes in adult patients with severe dengue in the critical and recovery phases of dengue infection
PLOS Neglected Tropical Diseases: published January 24, 2018 | https://doi.org/10.1371/journal.pntd.0006217
Presence of B. thailandensis and B. thailandensis expressing B. pseudomallei-like capsular polysaccharide in Thailand, and their associations with serological response to B. pseudomallei
PLOS Neglected Tropical Diseases: published January 24, 2018 | https://doi.org/10.1371/journal.pntd.0006193
Multifaceted functional implications of an endogenously expressed tRNA fragment in the vector mosquito Aedes aegypti
PLOS Neglected Tropical Diseases: published January 24, 2018 | https://doi.org/10.1371/journal.pntd.0006186
Defining objective clusters for rabies virus sequences using affinity propagation clustering
PLOS Neglected Tropical Diseases: published January 22, 2018 | https://doi.org/10.1371/journal.pntd.0006182
Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease
PLOS Neglected Tropical Diseases: published January 22, 2018 | https://doi.org/10.1371/journal.pntd.0006180
Molecular detection of airborne Emergomyces africanus, a thermally dimorphic fungal pathogen, in Cape Town, South Africa
PLOS Neglected Tropical Diseases: published January 22, 2018 | https://doi.org/10.1371/journal.pntd.0006174
Related Articles
Unreported cases in the 2014-2016 Ebola epidemic: Spatiotemporal variation, and implications for estimating transmission
PLOS Neglected Tropical Diseases: published January 22, 2018 | https://doi.org/10.1371/journal.pntd.0006161
MAIT cells are activated in acute Dengue virus infection and after in vitro Zika virus infection
PLOS Neglected Tropical Diseases: published January 22, 2018 | https://doi.org/10.1371/journal.pntd.0006154
Sanitation and water supply coverage thresholds associated with active trachoma: Modeling cross-sectional data from 13 countries
PLOS Neglected Tropical Diseases: published January 22, 2018 | https://doi.org/10.1371/journal.pntd.0006110
Environmental enteric dysfunction pathways and child stunting: A systematic review
PLOS Neglected Tropical Diseases: published January 19, 2018 | https://doi.org/10.1371/journal.pntd.0006205
Understanding the legal trade of cattle and camels and the derived risk of Rift Valley Fever introduction into and transmission within Egypt
PLOS Neglected Tropical Diseases: published January 19, 2018 | https://doi.org/10.1371/journal.pntd.0006143
Seasonally timed treatment programs for Ascaris lumbricoides to increase impact—An investigation using mathematical models
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006195
Inferring the risk factors behind the geographical spread and transmission of Zika in the Americas
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006194
Assessing the feasibility of interrupting the transmission of soil-transmitted helminths through mass drug administration: The DeWorm3 cluster randomized trial protocol
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006166
Related Articles
Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006160
Geographical distribution of soil transmitted helminths and the effects of community type in South Asia and South East Asia – A systematic review
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006153
Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006147
A comparative analysis of preservation techniques for the optimal molecular detection of hookworm DNA in a human fecal specimen
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006130
Testing for soil-transmitted helminth transmission elimination: Analysing the impact of the sensitivity of different diagnostic tools
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006114
Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0006020
Evaluating the sustainability, scalability, and replicability of an STH transmission interruption intervention: The DeWorm3 implementation science protocol
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0005988
Related Articles
Combined effectiveness of anthelmintic chemotherapy and WASH among HIV-infected adults
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0005955
Assessment of serum pharmacokinetics and urinary excretion of albendazole and its metabolites in human volunteers
PLOS Neglected Tropical Diseases: published January 18, 2018 | https://doi.org/10.1371/journal.pntd.0005945
Occupational exposure to human Mycobacterium bovis infection: A systematic review
PLOS Neglected Tropical Diseases: published January 16, 2018 | https://doi.org/10.1371/journal.pntd.0006208
L-arginine supplementation reduces mortality and improves disease outcome in mice infected with Trypanosoma cruzi
PLOS Neglected Tropical Diseases: published January 16, 2018 | https://doi.org/10.1371/journal.pntd.0006179
Modelling the large-scale yellow fever outbreak in Luanda, Angola, and the impact of vaccination
PLOS Neglected Tropical Diseases: published January 16, 2018 | https://doi.org/10.1371/journal.pntd.0006158
Isolation and complete genome analysis of neurotropic dengue virus serotype 3 from the cerebrospinal fluid of an encephalitis patient
PLOS Neglected Tropical Diseases: published January 12, 2018 | https://doi.org/10.1371/journal.pntd.0006198
Multi-drug resistant non-typhoidal Salmonella associated with invasive disease in western Kenya
PLOS Neglected Tropical Diseases: published January 12, 2018 | https://doi.org/10.1371/journal.pntd.0006156
Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation
PLOS Neglected Tropical Diseases: published January 12, 2018 | https://doi.org/10.1371/journal.pntd.0006141
Burkholderia pseudomallei modulates host iron homeostasis to facilitate iron availability and intracellular survival
PLOS Neglected Tropical Diseases: published January 12, 2018 | https://doi.org/10.1371/journal.pntd.0006096
Cognitive deficits and educational loss in children with schistosome infection—A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published January 12, 2018 | https://doi.org/10.1371/journal.pntd.0005524
Related Articles
Soil-transmitted helminth infection, loss of education and cognitive impairment in school-aged children: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published January 12, 2018 | https://doi.org/10.1371/journal.pntd.0005523
Related Articles
Mansonella perstans microfilaremic individuals are characterized by enhanced type 2 helper T and regulatory T and B cell subsets and dampened systemic innate and adaptive immune responses
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0006184
Bionomics of Phlebotomus argentipes in villages in Bihar, India with insights into efficacy of IRS-based control measures
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0006168
Population structure analysis of the neglected parasite Thelazia callipaeda revealed high genetic diversity in Eastern Asia isolates
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0006165
Barriers of attendance to dog rabies static point vaccination clinics in Blantyre, Malawi
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0006159
Mapping the geographical distribution of podoconiosis in Cameroon using parasitological, serological, and clinical evidence to exclude other causes of lymphedema
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0006126
Experimental transmission of West Nile Virus and Rift Valley Fever Virus by Culex pipiens from Lebanon
PLOS Neglected Tropical Diseases: published January 11, 2018 | https://doi.org/10.1371/journal.pntd.0005983
The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection
PLOS Neglected Tropical Diseases: published January 10, 2018 | https://doi.org/10.1371/journal.pntd.0006170
Polymorphisms in voltage-gated sodium channel gene and susceptibility of Aedes albopictus to insecticides in three districts of northern West Bengal, India
PLOS Neglected Tropical Diseases: published January 8, 2018 | https://doi.org/10.1371/journal.pntd.0006192
A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice
PLOS Neglected Tropical Diseases: published January 8, 2018 | https://doi.org/10.1371/journal.pntd.0006191
Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model
PLOS Neglected Tropical Diseases: published January 8, 2018 | https://doi.org/10.1371/journal.pntd.0006183
Tungiasis-related life quality impairment in children living in rural Kenya
PLOS Neglected Tropical Diseases: published January 8, 2018 | https://doi.org/10.1371/journal.pntd.0005939
Related Articles
Establishing Ebola Virus Disease (EVD) diagnostics using GeneXpert technology at a mobile laboratory in Liberia: Impact on outbreak response, case management and laboratory systems strengthening
PLOS Neglected Tropical Diseases: published January 5, 2018 | https://doi.org/10.1371/journal.pntd.0006135
Household expenditure on leprosy outpatient services in the Indian health system: A comparative study
PLOS Neglected Tropical Diseases: published January 4, 2018 | https://doi.org/10.1371/journal.pntd.0006181
Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model
PLOS Neglected Tropical Diseases: published January 4, 2018 | https://doi.org/10.1371/journal.pntd.0006116
Insecticide treated curtains and residual insecticide treatment to control Aedes aegypti: An acceptability study in Santiago de Cuba
PLOS Neglected Tropical Diseases: published January 2, 2018 | https://doi.org/10.1371/journal.pntd.0006115