Vaccination of hamsters with Opisthorchis viverrini extracellular vesicles and vesicle-derived recombinant tetraspanins induces antibodies that block vesicle uptake by cholangiocytes and reduce parasite burden after challenge infection

• Sujittra Chaiyadet,

  Roles Conceptualization, Methodology, Writing – original draft

  Affiliation Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Javier Sotillo,

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliation Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia

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• Watchara Krueajampa,

  Roles Methodology

  Affiliation Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Sophita Thongsen,

  Roles Methodology

  Affiliation Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Paul J. Brindley,

  Roles Funding acquisition, Resources

  Affiliation Department of Microbiology, Immunology and Tropical Medicine, and Research Center for Neglected Diseases of Poverty, School of Medicine & Health Sciences, George Washington University, Washington, DC, United States of America

  http://orcid.org/0000-0003-1765-0002

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• Banchob Sripa,

  Roles Resources

  Affiliation Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Alex Loukas ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: alex.loukas@jcu.edu.au (AL); thewa_la@kku.ac.th (TL)

  Affiliation Centre for Molecular Therapeutics, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns, Australia

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• Thewarach Laha

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: alex.loukas@jcu.edu.au (AL); thewa_la@kku.ac.th (TL)

  Affiliation Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

  http://orcid.org/0000-0003-1334-9976

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