Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis

Emma Birnie; Gavin C. K. W. Koh; Ester C. Löwenberg; Joost C. M. Meijers; Rapeephan R. Maude; Nicholas P. J. Day; Sharon J. Peacock; Tom van der Poll; W. Joost Wiersinga

doi:10.1371/journal.pntd.0005468

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Open Access

Peer-reviewed

Research Article

Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis

Emma Birnie ,

Contributed equally to this work with: Emma Birnie, Gavin C. K. W. Koh

Affiliation Center for Experimental and Molecular Medicine, Division of Infectious Diseases, Academic Medical Center, Amsterdam, The Netherlands
⨯
Gavin C. K. W. Koh ,

Contributed equally to this work with: Emma Birnie, Gavin C. K. W. Koh

Current address: Diseases of the Developing World, GlaxoSmithKline, Uxbridge, Middlesex, United Kingdom

Affiliations Center for Experimental and Molecular Medicine, Division of Infectious Diseases, Academic Medical Center, Amsterdam, The Netherlands, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kindom, Department of Infection and Tropical Medicine, Heartlands Hospital, Birmingham, United Kindom
⨯
Ester C. Löwenberg,

Affiliation Department of Experimental Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
⨯
Joost C. M. Meijers,

Affiliations Department of Experimental Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands, Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands
⨯
Rapeephan R. Maude,

Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
⨯
Nicholas P. J. Day,

Affiliations Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, The Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kindom
⨯
Sharon J. Peacock,

Affiliations Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Department of Medicine, University of Cambridge, Addenbrooke’s Hospital, Cambridge, United Kindom
⨯
Tom van der Poll,

Affiliation Center for Experimental and Molecular Medicine, Division of Infectious Diseases, Academic Medical Center, Amsterdam, The Netherlands
⨯
W. Joost Wiersinga

* E-mail: w.j.wiersinga@amc.uva.nl

Affiliation Center for Experimental and Molecular Medicine, Division of Infectious Diseases, Academic Medical Center, Amsterdam, The Netherlands
⨯

Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis

Emma Birnie,
Gavin C. K. W. Koh,
Ester C. Löwenberg,
Joost C. M. Meijers,
Rapeephan R. Maude,
Nicholas P. J. Day,
Sharon J. Peacock,
Tom van der Poll,
W. Joost Wiersinga

Published: March 15, 2017
https://doi.org/10.1371/journal.pntd.0005468

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