IRES-driven Expression of the Capsid Protein of the Venezuelan Equine Encephalitis Virus TC-83 Vaccine Strain Increases Its Attenuation and Safety

Mathilde Guerbois; Eugenia Volkova; Naomi L. Forrester; Shannan L. Rossi; Ilya Frolov; Scott C. Weaver

doi:10.1371/journal.pntd.0002197

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Open Access

Peer-reviewed

Research Article

IRES-driven Expression of the Capsid Protein of the Venezuelan Equine Encephalitis Virus TC-83 Vaccine Strain Increases Its Attenuation and Safety

Mathilde Guerbois,

Affiliation Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Eugenia Volkova,

Affiliations Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America, Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Naomi L. Forrester,

Affiliation Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Shannan L. Rossi,

Affiliation Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Ilya Frolov,

Current address: Department of Microbiology, University of Alabama, Birmingham, Alabama, United States of America.

Affiliation Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Scott C. Weaver

* E-mail: sweaver@utmb.edu

Affiliation Institute for Human Infections and Immunity, Sealy Center for Vaccine Development, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯

IRES-driven Expression of the Capsid Protein of the Venezuelan Equine Encephalitis Virus TC-83 Vaccine Strain Increases Its Attenuation and Safety

Mathilde Guerbois,
Eugenia Volkova,
Naomi L. Forrester,
Shannan L. Rossi,
Ilya Frolov,
Scott C. Weaver

Published: May 9, 2013
https://doi.org/10.1371/journal.pntd.0002197

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