Corallivorous crown-of-thorns sea stars are among the most influential keystone predators in tropical coral reef ecosystems. Adult populations undergo extreme population size fluctuations or outbreaks and can decimate coral reefs. Whole-genome sequencing of parent-offspring trios in this species revealed unexpectedly high mutation rates and reduced effective population size, despite population abundance exceeding 20- 90 million individuals. Such fundamental knowledge advances our understanding of mutation rate evolution and how genetic diversity is maintained in large marine populations. See Popovic et al. Download February's cover page.
Image Credit: Sven Uthicke
Research Articles
Tissue-specific and cis-regulatory changes underlie parallel, adaptive gene expression evolution in house mice
PLOS Genetics: published February 2, 2024 | https://doi.org/10.1371/journal.pgen.1010892
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High germline mutation rates, but not extreme population outbreaks, influence genetic diversity in a keystone coral predator
PLOS Genetics: published February 12, 2024 | https://doi.org/10.1371/journal.pgen.1011129
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The DNA helicase FANCJ (BRIP1) functions in double strand break repair processing, but not crossover formation during prophase I of meiosis in male mice
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Corrections
Correction: Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression
PLOS Genetics: published February 21, 2024 | https://doi.org/10.1371/journal.pgen.1011149
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PLOS Genetics: published February 27, 2024 | https://doi.org/10.1371/journal.pgen.1011133