This diminutive isopod crustacean, a predatory marine relative of the pill-bug, swarms in great numbers on surf beaches of NW Europe. Like many other inhabitants of the intertidal zones, Eurydice synchronises its biology to the 12.4h ebb and flow of the tides as well as the natural cycles of light and dark. Only recently are we beginning to dissect the molecular genetic basis of circatidal clocks in marine animals, and Eurydice is a key model in that endeavour. See Lin et al. Download October's cover page.
Image Credit: David Wilcockson
Research Articles
Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency
PLOS Genetics: published October 2, 2023 | https://doi.org/10.1371/journal.pgen.1010952
Genome-wide single-molecule analysis of long-read DNA methylation reveals heterogeneous patterns at heterochromatin that reflect nucleosome organisation
PLOS Genetics: published October 2, 2023 | https://doi.org/10.1371/journal.pgen.1010958
Microtubules oppose cortical actomyosin-driven membrane ingression during C. elegans meiosis I polar body extrusion
PLOS Genetics: published October 2, 2023 | https://doi.org/10.1371/journal.pgen.1010984
Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis
PLOS Genetics: published October 4, 2023 | https://doi.org/10.1371/journal.pgen.1010990
O antigen biogenesis sensitises Escherichia coli K-12 to bile salts, providing a plausible explanation for its evolutionary loss
PLOS Genetics: published October 4, 2023 | https://doi.org/10.1371/journal.pgen.1010996
Elevated levels of sphingolipid MIPC in the plasma membrane disrupt the coordination of cell growth with cell wall formation in fission yeast
PLOS Genetics: published October 4, 2023 | https://doi.org/10.1371/journal.pgen.1010987
Identification of a non-canonical ciliate nuclear genetic code where UAA and UAG code for different amino acids
PLOS Genetics: published October 5, 2023 | https://doi.org/10.1371/journal.pgen.1010913
Constructing and interpreting a large-scale variant effect map for an ultrarare disease gene: Comprehensive prediction of the functional impact of PSAT1 genotypes
PLOS Genetics: published October 9, 2023 | https://doi.org/10.1371/journal.pgen.1010972
The selfish yeast plasmid exploits a SWI/SNF-type chromatin remodeling complex for hitchhiking on chromosomes and ensuring high-fidelity propagation
PLOS Genetics: published October 9, 2023 | https://doi.org/10.1371/journal.pgen.1010986
Uptake of environmental DNA in Bacillus subtilis occurs all over the cell surface through a dynamic pilus structure
PLOS Genetics: published October 10, 2023 | https://doi.org/10.1371/journal.pgen.1010696
Demographically explicit scans for barriers to gene flow using gIMble
PLOS Genetics: published October 10, 2023 | https://doi.org/10.1371/journal.pgen.1010999
Insights into the conservation and diversification of the molecular functions of YTHDF proteins
PLOS Genetics: published October 10, 2023 | https://doi.org/10.1371/journal.pgen.1010980
Unanticipated domain requirements for Drosophila Wnk kinase in vivo
PLOS Genetics: published October 11, 2023 | https://doi.org/10.1371/journal.pgen.1010975
Transcriptomic comparison of two selective retinal cell ablation paradigms in zebrafish reveals shared and cell-specific regenerative responses
PLOS Genetics: published October 11, 2023 | https://doi.org/10.1371/journal.pgen.1010905
AGAMOUS mediates timing of guard cell formation during gynoecium development
PLOS Genetics: published October 11, 2023 | https://doi.org/10.1371/journal.pgen.1011000
Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia
PLOS Genetics: published October 13, 2023 | https://doi.org/10.1371/journal.pgen.1010989
CAG repeat expansion in the Huntington’s disease gene shapes linear and circular RNAs biogenesis
PLOS Genetics: published October 13, 2023 | https://doi.org/10.1371/journal.pgen.1010988
Revisiting evolutionary trajectories and the organization of the Pleolipoviridae family
PLOS Genetics: published October 13, 2023 | https://doi.org/10.1371/journal.pgen.1010998
Sensing of H2O2-induced oxidative stress by the UPF factor complex is crucial for activation of catalase-3 expression in Neurospora
PLOS Genetics: published October 16, 2023 | https://doi.org/10.1371/journal.pgen.1010985
Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits
PLOS Genetics: published October 16, 2023 | https://doi.org/10.1371/journal.pgen.1010977
A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells
PLOS Genetics: published October 16, 2023 | https://doi.org/10.1371/journal.pgen.1010979
The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system
PLOS Genetics: published October 16, 2023 | https://doi.org/10.1371/journal.pgen.1010841
lhCLIP reveals the in vivo RNA–RNA interactions recognized by hnRNPK
PLOS Genetics: published October 18, 2023 | https://doi.org/10.1371/journal.pgen.1011006
The parenting hub of the hypothalamus is a focus of imprinted gene action
PLOS Genetics: published October 19, 2023 | https://doi.org/10.1371/journal.pgen.1010961
Genome-wide analysis of horizontal transfer in non-model wild species from a natural ecosystem reveals new insights into genetic exchange in plants
PLOS Genetics: published October 19, 2023 | https://doi.org/10.1371/journal.pgen.1010964
The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach)
PLOS Genetics: published October 19, 2023 | https://doi.org/10.1371/journal.pgen.1011011
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An allelic series at the EDNRB2 locus controls diverse piebalding patterns in the domestic pigeon
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SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data
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A protease and a lipoprotein jointly modulate the conserved ExoR-ExoS-ChvI signaling pathway critical in Sinorhizobium meliloti for symbiosis with legume hosts
PLOS Genetics: published October 23, 2023 | https://doi.org/10.1371/journal.pgen.1010776
Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation
PLOS Genetics: published October 23, 2023 | https://doi.org/10.1371/journal.pgen.1010997
Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci
PLOS Genetics: published October 23, 2023 | https://doi.org/10.1371/journal.pgen.1010982
Wolbachia infection at least partially rescues the fertility and ovary defects of several new Drosophila melanogaster bag of marbles protein-coding mutants
PLOS Genetics: published October 23, 2023 | https://doi.org/10.1371/journal.pgen.1011009
The pleiotropic functions of Pri smORF peptides synchronize leg development regulators
PLOS Genetics: published October 30, 2023 | https://doi.org/10.1371/journal.pgen.1011004
Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs
PLOS Genetics: published October 31, 2023 | https://doi.org/10.1371/journal.pgen.1011014