February 2016

A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells

Min Hwa Shin, Yunlong He, Eryney Marrogi, Sajida Piperdi, Ling Ren, Chand Khanna, Richard Gorlick, Chengyu Liu, Jing Huang

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005884

Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization

Smita Mohanty, Krishnadev Oruganty, Annie Kwon, Dominic P. Byrne, Samantha Ferries, Zheng Ruan, Laura E. Hanold, Samiksha Katiyar, Eileen J. Kennedy, Patrick A. Eyers, Natarajan Kannan

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005885

Genomics of Rapid Incipient Speciation in Sympatric Threespine Stickleback

David A. Marques, Kay Lucek, Joana I. Meier, Salome Mwaiko, Catherine E. Wagner, Laurent Excoffier, Ole Seehausen

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005887

A Parent-of-Origin Effect Impacts the Phenotype in Low Penetrance Retinoblastoma Families Segregating the c.1981C>T/p.Arg661Trp Mutation of RB1

Philippine Eloy, Catherine Dehainault, Meriem Sefta, Isabelle Aerts, François Doz, Nathalie Cassoux, Livia Lumbroso le Rouic, Dominique Stoppa-Lyonnet, François Radvanyi, Gaël A. Millot, Marion Gauthier-Villars, Claude Houdayer

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005888

The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

Deng-Fu Guo, Huxing Cui, Qihong Zhang, Donald A. Morgan, Daniel R. Thedens, Darryl Nishimura, Justin L. Grobe, Val C. Sheffield, Kamal Rahmouni

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005890

Maintenance of Tissue Pluripotency by Epigenetic Factors Acting at Multiple Levels

Devendran A. Sadasivam, Der-Hwa Huang

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005897

Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells

Xinlei Lian, Jiahui Guo, Wei Gu, Yizhi Cui, Jiayong Zhong, Jingjie Jin, Qing-Yu He, Tong Wang, Gong Zhang

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005901

SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane

Meghan A. Morrissey, Ranjay Jayadev, Ginger R. Miley, Catherine A. Blebea, Qiuyi Chi, Shinji Ihara, David R. Sherwood

PLOS Genetics: published February 29, 2016 | https://doi.org/10.1371/journal.pgen.1005905

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia

You Li, Hisato Yagi, Ezenwa Obi Onuoha, Rama Rao Damerla, Richard Francis, Yoshiyuki Furutani, Muhammad Tariq, Stephen M. King, Gregory Hendricks, Cheng Cui, Manush Saydmohammed, Dong Min Lee, Maliha Zahid, Iman Sami, Linda Leatherbury, Gregory J. Pazour, Stephanie M. Ware, Toshio Nakanishi, Elizabeth Goldmuntz, Michael Tsang, Cecilia W. Lo

PLOS Genetics: published February 26, 2016 | https://doi.org/10.1371/journal.pgen.1005821

Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span

Sandeep Kumar, Nicholas Dietrich, Kerry Kornfeld

PLOS Genetics: published February 26, 2016 | https://doi.org/10.1371/journal.pgen.1005866

Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age

Nikolay A. Ivanov, Ran Tao, Joshua G. Chenoweth, Anna Brandtjen, Michelle I. Mighdoll, John D. Genova, Ronald D. McKay, Yankai Jia, Daniel R. Weinberger, Joel E. Kleinman, Thomas M. Hyde, Andrew E. Jaffe

PLOS Genetics: published February 25, 2016 | https://doi.org/10.1371/journal.pgen.1005819

Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies

Seung Hoan Choi, Daniela Ruggiero, Rossella Sorice, Ci Song, Teresa Nutile, Albert Vernon Smith, Maria Pina Concas, Michela Traglia, Caterina Barbieri, Ndeye Coumba Ndiaye, Maria G. Stathopoulou, Vasiliki Lagou, Giovanni Battista Maestrale, Cinzia Sala, Stephanie Debette, Peter Kovacs, Lars Lind, John Lamont, Peter Fitzgerald, Anke Tönjes, Vilmundur Gudnason, Daniela Toniolo, Mario Pirastu, Celine Bellenguez, Ramachandran S. Vasan, Erik Ingelsson, Anne-Louise Leutenegger, Andrew D. Johnson, Anita L. DeStefano, Sophie Visvikis-Siest, Sudha Seshadri, Marina Ciullo

PLOS Genetics: published February 24, 2016 | https://doi.org/10.1371/journal.pgen.1005874

Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans

Miki Fujioka, Hemlata Mistry, Paul Schedl, James B. Jaynes

PLOS Genetics: published February 24, 2016 | https://doi.org/10.1371/journal.pgen.1005889

An Energy-Independent Pro-longevity Function of Triacylglycerol in Yeast

Witawas Handee, Xiaobo Li, Kevin W. Hall, Xiexiong Deng, Pan Li, Christoph Benning, Barry L. Williams, Min-Hao Kuo

PLOS Genetics: published February 23, 2016 | https://doi.org/10.1371/journal.pgen.1005878

3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells

Yonit Hoffman, Debora Rosa Bublik, Alejandro P. Ugalde, Ran Elkon, Tammy Biniashvili, Reuven Agami, Moshe Oren, Yitzhak Pilpel

PLOS Genetics: published February 23, 2016 | https://doi.org/10.1371/journal.pgen.1005879

MEF2C and EBF1 Co-regulate B Cell-Specific Transcription

Nikki R. Kong, Matthew Davis, Li Chai, Astar Winoto, Robert Tjian

PLOS Genetics: published February 22, 2016 | https://doi.org/10.1371/journal.pgen.1005845

Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding?

Gregory A. Moyerbrailean, Cynthia A. Kalita, Chris T. Harvey, Xiaoquan Wen, Francesca Luca, Roger Pique-Regi

PLOS Genetics: published February 22, 2016 | https://doi.org/10.1371/journal.pgen.1005875

Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility

Richarda M. de Voer, Marc-Manuel Hahn, Robbert D. A. Weren, Arjen R. Mensenkamp, Christian Gilissen, Wendy A. van Zelst-Stams, Liesbeth Spruijt, C. Marleen Kets, Junxiao Zhang, Hanka Venselaar, Lilian Vreede, Nil Schubert, Marloes Tychon, Ronny Derks, Hans K. Schackert, Ad Geurts van Kessel, Nicoline Hoogerbrugge, Marjolijn J. L. Ligtenberg, Roland P. Kuiper

PLOS Genetics: published February 22, 2016 | https://doi.org/10.1371/journal.pgen.1005880

Liver-Enriched Gene 1, a Glycosylated Secretory Protein, Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish

Minjie Hu, Yun Bai, Chunxia Zhang, Feng Liu, Zongbin Cui, Jun Chen, Jinrong Peng

PLOS Genetics: published February 22, 2016 | https://doi.org/10.1371/journal.pgen.1005881

C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction

Ashlyn M. Spring, Douglas J. Brusich, C. Andrew Frank

PLOS Genetics: published February 22, 2016 | https://doi.org/10.1371/journal.pgen.1005886

Systems Level Analyses Reveal Multiple Regulatory Activities of CodY Controlling Metabolism, Motility and Virulence in Listeria monocytogenes

Lior Lobel, Anat A. Herskovits

PLOS Genetics: published February 19, 2016 | https://doi.org/10.1371/journal.pgen.1005870

NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators

Dominic Landgraf, Lexie L. Wang, Tanja Diemer, David K. Welsh

PLOS Genetics: published February 19, 2016 | https://doi.org/10.1371/journal.pgen.1005882

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

Ryutaro Uchi, Yusuke Takahashi, Atsushi Niida, Teppei Shimamura, Hidenari Hirata, Keishi Sugimachi, Genta Sawada, Takeshi Iwaya, Junji Kurashige, Yoshiaki Shinden, Tomohiro Iguchi, Hidetoshi Eguchi, Kenichi Chiba, Yuichi Shiraishi, Genta Nagae, Kenichi Yoshida, Yasunobu Nagata, Hiroshi Haeno, Hirofumi Yamamoto, Hideshi Ishii, Yuichiro Doki, Hisae Iinuma, Shin Sasaki, Satoshi Nagayama, Kazutaka Yamada, Shinichi Yachida, Mamoru Kato, Tatsuhiro Shibata, Eiji Oki, Hiroshi Saeki, Ken Shirabe, Yoshinao Oda, Yoshihiko Maehara, Shizuo Komune, Masaki Mori, Yutaka Suzuki, Ken Yamamoto, Hiroyuki Aburatani, Seishi Ogawa, Satoru Miyano, Koshi Mimori

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005778

Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors

Nozomi Iwanami, Yuri Nakamura, Takunori Satoh, Ziguang Liu, Akiko K. Satoh

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005828

Bovine Host Genetic Variation Influences Rumen Microbial Methane Production with Best Selection Criterion for Low Methane Emitting and Efficiently Feed Converting Hosts Based on Metagenomic Gene Abundance

Rainer Roehe, Richard J. Dewhurst, Carol-Anne Duthie, John A. Rooke, Nest McKain, Dave W. Ross, Jimmy J. Hyslop, Anthony Waterhouse, Tom C. Freeman, Mick Watson, R. John Wallace

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005846

Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12

Netta Mäkinen, Mervi Aavikko, Tuomas Heikkinen, Minna Taipale, Jussi Taipale, Riitta Koivisto-Korander, Ralf Bützow, Pia Vahteristo

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005850

Synergistic Control of Kinetochore Protein Levels by Psh1 and Ubr2

Eva Herrero, Peter H. Thorpe

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005855

Ingression Progression Complexes Control Extracellular Matrix Remodelling during Cytokinesis in Budding Yeast

Magdalena Foltman, Iago Molist, Irene Arcones, Carlos Sacristan, Yasmina Filali-Mouncef, Cesar Roncero, Alberto Sanchez-Diaz

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005864

The Interplay between Myc and CTP Synthase in Drosophila

Gabriel N. Aughey, Stuart J. Grice, Ji-Long Liu

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005867

A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5’-3’ Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe

James Franklin Tucker, Corina Ohle, Géza Schermann, Katja Bendrin, Wei Zhang, Tamás Fischer, Ke Zhang

PLOS Genetics: published February 18, 2016 | https://doi.org/10.1371/journal.pgen.1005873

Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer

Dvir Aran, Monther Abu-Remaileh, Revital Levy, Nurit Meron, Gidon Toperoff, Yifat Edrei, Yehudit Bergman, Asaf Hellman

PLOS Genetics: published February 17, 2016 | https://doi.org/10.1371/journal.pgen.1005840

Mps1^Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20^Slp1-APC/C and Maintain Spindle Checkpoint Arrests

Judith Zich, Karen May, Konstantinos Paraskevopoulos, Onur Sen, Heather M. Syred, Sjaak van der Sar, Hitesh Patel, James J. Moresco, Ali Sarkeshik, John R. Yates III, Juri Rappsilber, Kevin G. Hardwick

PLOS Genetics: published February 16, 2016 | https://doi.org/10.1371/journal.pgen.1005834

Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes

Thomas Arbogast, Abdel-Mouttalib Ouagazzal, Claire Chevalier, Maksym Kopanitsa, Nurudeen Afinowi, Eugenia Migliavacca, Belinda S. Cowling, Marie-Christine Birling, Marie-France Champy, Alexandre Reymond, Yann Herault

PLOS Genetics: published February 12, 2016 | https://doi.org/10.1371/journal.pgen.1005709

RecG Directs DNA Synthesis during Double-Strand Break Repair

Benura Azeroglu, Julia S. P. Mawer, Charlotte A. Cockram, Martin A. White, A. M. Mahedi Hasan, Milana Filatenkova, David R. F. Leach

PLOS Genetics: published February 12, 2016 | https://doi.org/10.1371/journal.pgen.1005799

The Epigenomic Landscape of Prokaryotes

Matthew J. Blow, Tyson A. Clark, Chris G. Daum, Adam M. Deutschbauer, Alexey Fomenkov, Roxanne Fries, Jeff Froula, Dongwan D. Kang, Rex R. Malmstrom, Richard D. Morgan, Janos Posfai, Kanwar Singh, Axel Visel, Kelly Wetmore, Zhiying Zhao, Edward M. Rubin, Jonas Korlach, Len A. Pennacchio, Richard J. Roberts

PLOS Genetics: published February 12, 2016 | https://doi.org/10.1371/journal.pgen.1005854

TDM1 Regulation Determines the Number of Meiotic Divisions

Marta Cifuentes, Sylvie Jolivet, Laurence Cromer, Hirofumi Harashima, Petra Bulankova, Charlotte Renne, Wayne Crismani, Yuko Nomura, Hirofumi Nakagami, Keiko Sugimoto, Arp Schnittger, Karel Riha, Raphael Mercier

PLOS Genetics: published February 12, 2016 | https://doi.org/10.1371/journal.pgen.1005856

Carriage of λ Latent Virus Is Costly for Its Bacterial Host due to Frequent Reactivation in Monoxenic Mouse Intestine

Marianne De Paepe, Laurent Tournier, Elisabeth Moncaut, Olivier Son, Philippe Langella, Marie-Agnès Petit

PLOS Genetics: published February 12, 2016 | https://doi.org/10.1371/journal.pgen.1005861

Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2

Jung-Sik Kim, Xiaoyuan He, Bernardo Orr, Gordana Wutz, Victoria Hill, Jan-Michael Peters, Duane A. Compton, Todd Waldman

PLOS Genetics: published February 12, 2016 | https://doi.org/10.1371/journal.pgen.1005865

The Quantitative Basis of the Arabidopsis Innate Immune System to Endemic Pathogens Depends on Pathogen Genetics

Jason A. Corwin, Daniel Copeland, Julie Feusier, Anushriya Subedy, Robert Eshbaugh, Christine Palmer, Julin Maloof, Daniel J. Kliebenstein

PLOS Genetics: published February 11, 2016 | https://doi.org/10.1371/journal.pgen.1005789

DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans

Francis Raj Gandhi Amrit, Elizabeth Marie Steenkiste, Ramesh Ratnappan, Shaw-Wen Chen, T. Brooke McClendon, Dennis Kostka, Judith Yanowitz, Carissa Perez Olsen, Arjumand Ghazi

PLOS Genetics: published February 10, 2016 | https://doi.org/10.1371/journal.pgen.1005788

A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4

Svetlana V. Masyukova, Dawn E. Landis, Scott J. Henke, Corey L. Williams, Jay N. Pieczynski, Kelly N. Roszczynialski, Jannese E. Covington, Erik B. Malarkey, Bradley K. Yoder

PLOS Genetics: published February 10, 2016 | https://doi.org/10.1371/journal.pgen.1005841

Strong Selection at MHC in Mexicans since Admixture

Quan Zhou, Liang Zhao, Yongtao Guan

PLOS Genetics: published February 10, 2016 | https://doi.org/10.1371/journal.pgen.1005847

A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects

Katherine Stewart, Yaned Gaitan, Maxwell E. R. Shafer, Lamine Aoudjit, Di Hu, Richa Sharma, Mathieu Tremblay, Hidetaka Ishii, Michael Marcotte, Daniela Stanga, You Chi Tang, Sami Kamel Boualia, Alana H. T. Nguyen, Tomoko Takano, Nathalie Lamarche-Vane, Silvia Vidal, Maxime Bouchard

PLOS Genetics: published February 9, 2016 | https://doi.org/10.1371/journal.pgen.1005785

The Replisome-Coupled E3 Ubiquitin Ligase Rtt101^Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress

Raymond Buser, Vanessa Kellner, Andre Melnik, Caroline Wilson-Zbinden, René Schellhaas, Lisa Kastner, Wojciech Piwko, Martina Dees, Paola Picotti, Marija Maric, Karim Labib, Brian Luke, Matthias Peter

PLOS Genetics: published February 5, 2016 | https://doi.org/10.1371/journal.pgen.1005843

Nucleolar DEAD-Box RNA Helicase TOGR1 Regulates Thermotolerant Growth as a Pre-rRNA Chaperone in Rice

Dong Wang, Baoxiang Qin, Xiang Li, Ding Tang, Yu’e Zhang, Zhukuan Cheng, Yongbiao Xue

PLOS Genetics: published February 5, 2016 | https://doi.org/10.1371/journal.pgen.1005844

Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs

Zita Nagy, Alkmini Kalousi, Audrey Furst, Marc Koch, Benoit Fischer, Evi Soutoglou

PLOS Genetics: published February 4, 2016 | https://doi.org/10.1371/journal.pgen.1005791

Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries

Ai Tian, Hassina Benchabane, Zhenghan Wang, Yashi Ahmed

PLOS Genetics: published February 4, 2016 | https://doi.org/10.1371/journal.pgen.1005822

Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration

Jin Xu, Jiaxi Cui, Aranzazu Del Campo, Chong Hyun Shin

PLOS Genetics: published February 4, 2016 | https://doi.org/10.1371/journal.pgen.1005831

Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation

Richard H. Little, Lucia Grenga, Gerhard Saalbach, Alexandra M. Howat, Sebastian Pfeilmeier, Eleftheria Trampari, Jacob G. Malone

PLOS Genetics: published February 4, 2016 | https://doi.org/10.1371/journal.pgen.1005837

Repeat-Associated Fission Yeast-Like Regional Centromeres in the Ascomycetous Budding Yeast Candida tropicalis

Gautam Chatterjee, Sundar Ram Sankaranarayanan, Krishnendu Guin, Yogitha Thattikota, Sreedevi Padmanabhan, Rahul Siddharthan, Kaustuv Sanyal

PLOS Genetics: published February 4, 2016 | https://doi.org/10.1371/journal.pgen.1005839

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression

David B. West, Eric K. Engelhard, Michael Adkisson, A. J. Nava, Julia V. Kirov, Andreanna Cipollone, Brandon Willis, Jared Rapp, Pieter J. de Jong, Kent C. Lloyd

PLOS Genetics: published February 3, 2016 | https://doi.org/10.1371/journal.pgen.1005691

Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation

Charley Xia, Carmen Amador, Jennifer Huffman, Holly Trochet, Archie Campbell, David Porteous, Generation Scotland, Nicholas D. Hastie, Caroline Hayward, Veronique Vitart, Pau Navarro, Chris S. Haley

PLOS Genetics: published February 2, 2016 | https://doi.org/10.1371/journal.pgen.1005804

GBStools: A Statistical Method for Estimating Allelic Dropout in Reduced Representation Sequencing Data

Thomas F. Cooke, Muh-Ching Yee, Marina Muzzio, Alexandra Sockell, Ryan Bell, Omar E. Cornejo, Joanna L. Kelley, Graciela Bailliet, Claudio M. Bravi, Carlos D. Bustamante, Eimear E. Kenny

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005631

Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies

Xiaolei Liu, Meng Huang, Bin Fan, Edward S. Buckler, Zhiwu Zhang

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005767

Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion

Raphaëlle Laureau, Sophie Loeillet, Francisco Salinas, Anders Bergström, Patricia Legoix-Né, Gianni Liti, Alain Nicolas

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005781

Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross

Anna L. Tyler, Leah Rae Donahue, Gary A. Churchill, Gregory W. Carter

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005805

The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis

Kian Hématy, Yannick Bellec, Ram Podicheti, Nathalie Bouteiller, Pauline Anne, Céline Morineau, Richard P. Haslam, Frederic Beaudoin, Johnathan A. Napier, Keithanne Mockaitis, Dominique Gagliardi, Hervé Vaucheret, Heike Lange, Jean-Denis Faure

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005817

Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway

Scott A. Keith, Sarah K. Maddux, Yayu Zhong, Meghna N. Chinchankar, Annabel A. Ferguson, Arjumand Ghazi, Alfred L. Fisher

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005823

A Mutation in PMP2 Causes Dominant Demyelinating Charcot-Marie-Tooth Neuropathy

Young Bin Hong, Jaesoon Joo, Young Se Hyun, Geon Kwak, Yu-Ri Choi, Ha Kyung Yeo, Dong Hwan Jwa, Eun Ja Kim, Won Min Mo, Soo Hyun Nam, Sung Min Kim, Jeong Hyun Yoo, Heasoo Koo, Hwan Tae Park, Ki Wha Chung, Byung-Ok Choi

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005829

Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development

Yun Huang, Cui-Zhu Feng, Qing Ye, Wei-Hua Wu, Yi-Fang Chen

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005833

Continuous Influx of Genetic Material from Host to Virus Populations

Clément Gilbert, Jean Peccoud, Aurélien Chateigner, Bouziane Moumen, Richard Cordaux, Elisabeth A. Herniou

PLOS Genetics: published February 1, 2016 | https://doi.org/10.1371/journal.pgen.1005838

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Genomics of rapid incipient speciation in sympatric threespine stickleback.

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