March 2011

Estimating Divergence Time and Ancestral Effective Population Size of Bornean and Sumatran Orangutan Subspecies Using a Coalescent Hidden Markov Model

Thomas Mailund, Julien Y. Dutheil, Asger Hobolth, Gerton Lunter, Mikkel H. Schierup

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1001319

SUMO-Targeted Ubiquitin Ligase, Rad60, and Nse2 SUMO Ligase Suppress Spontaneous Top1–Mediated DNA Damage and Genome Instability

Johanna Heideker, John Prudden, J. Jefferson P. Perry, John A. Tainer, Michael N. Boddy

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1001320

Initial Mutations Direct Alternative Pathways of Protein Evolution

Merijn L. M. Salverda, Eynat Dellus, Florien A. Gorter, Alfons J. M. Debets, John van der Oost, Rolf F. Hoekstra, Dan S. Tawfik, J. Arjan G. M. de Visser

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1001321

Testing for an Unusual Distribution of Rare Variants

Benjamin M. Neale, Manuel A. Rivas, Benjamin F. Voight, David Altshuler, Bernie Devlin, Marju Orho-Melander, Sekar Kathiresan, Shaun M. Purcell, Kathryn Roeder, Mark J. Daly

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1001322

Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production

Sharon A. Chung, Kimberly E. Taylor, Robert R. Graham, Joanne Nititham, Annette T. Lee, Ward A. Ortmann, Chaim O. Jacob, Marta E. Alarcón-Riquelme, Betty P. Tsao, John B. Harley, Patrick M. Gaffney, Kathy L. Moser, SLEGEN, Michelle Petri, F. Yesim Demirci, M. Ilyas Kamboh, Susan Manzi, Peter K. Gregersen, Carl D. Langefeld, Timothy W. Behrens, Lindsey A. Criswell

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1001323

Diverse Roles and Interactions of the SWI/SNF Chromatin Remodeling Complex Revealed Using Global Approaches

Ghia M. Euskirchen, Raymond K. Auerbach, Eugene Davidov, Tara A. Gianoulis, Guoneng Zhong, Joel Rozowsky, Nitin Bhardwaj, Mark B. Gerstein, Michael Snyder

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1002008

A Bow-Tie Genetic Architecture for Morphogenesis Suggested by a Genome-Wide RNAi Screen in Caenorhabditis elegans

Matthew D. Nelson, Elinor Zhou, Karin Kiontke, Hélène Fradin, Grayson Maldonado, Daniel Martin, Khushbu Shah, David H. A. Fitch

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1002010

FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration

Cao Huang, Hongxia Zhou, Jianbin Tong, Han Chen, Yong-Jian Liu, Dian Wang, Xiaotao Wei, Xu-Gang Xia

PLOS Genetics: published March 3, 2011 | https://doi.org/10.1371/journal.pgen.1002011

Polycomb Repressive Complex 2 Controls the Embryo-to-Seedling Phase Transition

Daniel Bouyer, Francois Roudier, Maren Heese, Ellen D. Andersen, Delphine Gey, Moritz K. Nowack, Justin Goodrich, Jean-Pierre Renou, Paul E. Grini, Vincent Colot, Arp Schnittger

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1002014

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

Elizabeth K. Speliotes, Laura M. Yerges-Armstrong, Jun Wu, Ruben Hernaez, Lauren J. Kim, Cameron D. Palmer, Vilmundur Gudnason, Gudny Eiriksdottir, Melissa E. Garcia, Lenore J. Launer, Michael A. Nalls, Jeanne M. Clark, Braxton D. Mitchell, Alan R. Shuldiner, Johannah L. Butler, Marta Tomas, Udo Hoffmann, Shih-Jen Hwang, Joseph M. Massaro, Christopher J. O'Donnell, Dushyant V. Sahani, Veikko Salomaa, Eric E. Schadt, Stephen M. Schwartz, David S. Siscovick, NASH CRN, GIANT Consortium, MAGIC Investigators, Benjamin F. Voight, J. Jeffrey Carr, Mary F. Feitosa, Tamara B. Harris, Caroline S. Fox, Albert V. Smith, W. H. Linda Kao, Joel N. Hirschhorn, Ingrid B. Borecki, GOLD Consortium

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001324

The SUVR4 Histone Lysine Methyltransferase Binds Ubiquitin and Converts H3K9me1 to H3K9me3 on Transposon Chromatin in Arabidopsis

Silje V. Veiseth, Mohummad A. Rahman, Kyoko L. Yap, Andreas Fischer, Wolfgang Egge-Jacobsen, Gunter Reuter, Ming-Ming Zhou, Reidunn B. Aalen, Tage Thorstensen

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001325

A Cholinergic-Regulated Circuit Coordinates the Maintenance and Bi-Stable States of a Sensory-Motor Behavior during Caenorhabditis elegans Male Copulation

Yishi Liu, Brigitte LeBeouf, Xiaoyan Guo, Paola A. Correa, Daisy G. Gualberto, Robyn Lints, L. Rene Garcia

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001326

Global Analysis of the Relationship between JIL-1 Kinase and Transcription

Catherine Regnard, Tobias Straub, Angelika Mitterweger, Ina K. Dahlsveen, Viola Fabian, Peter B. Becker

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001327

Identification of a Novel Type of Spacer Element Required for Imprinting in Fission Yeast

Suha Sayrac, Sonya Vengrova, Emma L. Godfrey, Jacob Z. Dalgaard

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001328

Chiasmata Promote Monopolar Attachment of Sister Chromatids and Their Co-Segregation toward the Proper Pole during Meiosis I

Yukinobu Hirose, Ren Suzuki, Tatsunori Ohba, Yumi Hinohara, Hirotada Matsuhara, Masashi Yoshida, Yuta Itabashi, Hiroshi Murakami, Ayumu Yamamoto

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001329

Arabidopsis COMPASS-Like Complexes Mediate Histone H3 Lysine-4 Trimethylation to Control Floral Transition and Plant Development

Danhua Jiang, Nicholas C. Kong, Xiaofeng Gu, Zicong Li, Yuehui He

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001330

Global Developmental Gene Expression and Pathway Analysis of Normal Brain Development and Mouse Models of Human Neuronal Migration Defects

Tiziano Pramparo, Ondrej Libiger, Sonia Jain, Hong Li, Yong Ha Youn, Shinji Hirotsune, Nicholas J. Schork, Anthony Wynshaw-Boris

PLOS Genetics: published March 10, 2011 | https://doi.org/10.1371/journal.pgen.1001331

Replicative Age Induces Mitotic Recombination in the Ribosomal RNA Gene Cluster of Saccharomyces cerevisiae

Derek L. Lindstrom, Christina K. Leverich, Kiersten A. Henderson, Daniel E. Gottschling

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1002015

H3K9me2/3 Binding of the MBT Domain Protein LIN-61 Is Essential for Caenorhabditis elegans Vulva Development

Nora Koester-Eiserfunke, Wolfgang Fischle

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1002017

Sensing of Replication Stress and Mec1 Activation Act through Two Independent Pathways Involving the 9-1-1 Complex and DNA Polymerase ε

Fabio Puddu, Gabriele Piergiovanni, Paolo Plevani, Marco Muzi-Falconi

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1002022

Rif1 Supports the Function of the CST Complex in Yeast Telomere Capping

Savani Anbalagan, Diego Bonetti, Giovanna Lucchini, Maria Pia Longhese

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1002024

Phenotype Restricted Genome-Wide Association Study Using a Gene-Centric Approach Identifies Three Low-Risk Neuroblastoma Susceptibility Loci

Lễ B. Nguyễn, Sharon J. Diskin, Mario Capasso, Kai Wang, Maura A. Diamond, Joseph Glessner, Cecilia Kim, Edward F. Attiyeh, Yael P. Mosse, Kristina Cole, Achille Iolascon, Marcella Devoto, Hakon Hakonarson, Hongzhe K. Li, John M. Maris

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1002026

A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs

Mia Olsson, Jennifer R. S. Meadows, Katarina Truvé, Gerli Rosengren Pielberg, Francesca Puppo, Evan Mauceli, Javier Quilez, Noriko Tonomura, Giordana Zanna, Maria José Docampo, Anna Bassols, Anne C. Avery, Elinor K. Karlsson, Anne Thomas, Daniel L. Kastner, Erik Bongcam-Rudloff, Matthew T. Webster, Armand Sanchez, Åke Hedhammar, Elaine F. Remmers, Leif Andersson, Lluis Ferrer, Linda Tintle, Kerstin Lindblad-Toh

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001332

A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium

James D. McKay, Therese Truong, Valerie Gaborieau, Amelie Chabrier, Shu-Chun Chuang, Graham Byrnes, David Zaridze, Oxana Shangina, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, Peter Rudnai, Eleonora Fabianova, Alexandru Bucur, Vladimir Bencko, Ivana Holcatova, Vladimir Janout, Lenka Foretova, Pagona Lagiou, Dimitrios Trichopoulos, Simone Benhamou, Christine Bouchardy, Wolfgang Ahrens, Franco Merletti, Lorenzo Richiardi, Renato Talamini, Luigi Barzan, Kristina Kjaerheim, Gary J. Macfarlane, Tatiana V. Macfarlane, Lorenzo Simonato, Cristina Canova, Antonio Agudo, Xavier Castellsagué, Ray Lowry, David I. Conway, Patricia A. McKinney, Claire M. Healy, Mary E. Toner, Ariana Znaor, Maria Paula Curado, Sergio Koifman, Ana Menezes, Victor Wünsch-Filho, José Eluf Neto, Leticia Fernández Garrote, Stefania Boccia, Gabriella Cadoni, Dario Arzani, Andrew F. Olshan, Mark C. Weissler, William K. Funkhouser, Jingchun Luo, Jan Lubiński, Joanna Trubicka, Marcin Lener, Dorota Oszutowska, Stephen M. Schwartz, Chu Chen, Sherianne Fish, David R. Doody, Joshua E. Muscat, Philip Lazarus, Carla J. Gallagher, Shen-Chih Chang, Zuo-Feng Zhang, Qingyi Wei, Erich M. Sturgis, Li-E Wang, Silvia Franceschi, Rolando Herrero, Karl T. Kelsey, Michael D. McClean, Carmen J. Marsit, Heather H. Nelson, Marjorie Romkes, Shama Buch, Tomoko Nukui, Shilong Zhong, Martin Lacko, Johannes J. Manni, Wilbert H. M. Peters, Rayjean J. Hung, John McLaughlin, Lars Vatten, Inger Njølstad, Gary E. Goodman, John K. Field, Triantafillos Liloglou, Paolo Vineis, Francoise Clavel-Chapelon, Domenico Palli, Rosario Tumino, Vittorio Krogh, Salvatore Panico, Carlos A. González, J. Ramón Quirós, Carmen Martínez, Carmen Navarro, Eva Ardanaz, Nerea Larrañaga, Kay-Tee Khaw, Timothy Key, H. Bas Bueno-de-Mesquita, Petra H. M. Peeters, Antonia Trichopoulou, Jakob Linseisen, Heiner Boeing, Göran Hallmans, Kim Overvad, Anne Tjønneland, Merethe Kumle, Elio Riboli, Kristjan Välk, Tõnu Voodern, Andres Metspalu, Diana Zelenika, Anne Boland, Marc Delepine, Mario Foglio, Doris Lechner, Hélène Blanché, Ivo G. Gut, Pilar Galan, Simon Heath, Mia Hashibe, Richard B. Hayes, Paolo Boffetta, Mark Lathrop, Paul Brennan

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001333

The FUN30 Chromatin Remodeler, Fft3, Protects Centromeric and Subtelomeric Domains from Euchromatin Formation

Annelie Strålfors, Julian Walfridsson, Hasanuzzaman Bhuiyan, Karl Ekwall

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001334

Role of the Drosophila Non-Visual ß-Arrestin Kurtz in Hedgehog Signalling

Cristina Molnar, Ana Ruiz-Gómez, Mercedes Martín, Susana Rojo-Berciano, Federico Mayor Jr., Jose F. de Celis

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001335

Population-Based Resequencing of Experimentally Evolved Populations Reveals the Genetic Basis of Body Size Variation in Drosophila melanogaster

Thomas L. Turner, Andrew D. Stewart, Andrew T. Fields, William R. Rice, Aaron M. Tarone

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001336

Quantifying the Underestimation of Relative Risks from Genome-Wide Association Studies

Chris Spencer, Eliana Hechter, Damjan Vukcevic, Peter Donnelly

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001337

Genome-Wide Interaction-Based Association Analysis Identified Multiple New Susceptibility Loci for Common Diseases

Yang Liu, Haiming Xu, Suchao Chen, Xianfeng Chen, Zhenguo Zhang, Zhihong Zhu, Xueying Qin, Landian Hu, Jun Zhu, Guo-Ping Zhao, Xiangyin Kong

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001338

Expanded CAG/CTG Repeat DNA Induces a Checkpoint Response That Impacts Cell Proliferation in Saccharomyces cerevisiae

Rangapriya Sundararajan, Catherine H. Freudenreich

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001339

Triplet Repeat–Derived siRNAs Enhance RNA–Mediated Toxicity in a Drosophila Model for Myotonic Dystrophy

Zhenming Yu, Xiuyin Teng, Nancy M. Bonini

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001340

Macoilin, a Conserved Nervous System–Specific ER Membrane Protein That Regulates Neuronal Excitability

Fausto Arellano-Carbajal, Luis Briseño-Roa, Africa Couto, Benny H. H. Cheung, Michel Labouesse, Mario de Bono

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001341

A Molecular Phylogeny of Living Primates

Polina Perelman, Warren E. Johnson, Christian Roos, Hector N. Seuánez, Julie E. Horvath, Miguel A. M. Moreira, Bailey Kessing, Joan Pontius, Melody Roelke, Yves Rumpler, Maria Paula C. Schneider, Artur Silva, Stephen J. O'Brien, Jill Pecon-Slattery

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001342

Viral Genome Segmentation Can Result from a Trade-Off between Genetic Content and Particle Stability

Samuel Ojosnegros, Juan García-Arriaza, Cristina Escarmís, Susanna C. Manrubia, Celia Perales, Armando Arias, Mauricio García Mateu, Esteban Domingo

PLOS Genetics: published March 17, 2011 | https://doi.org/10.1371/journal.pgen.1001344

Interactions among Polycomb Domains Are Guided by Chromosome Architecture

Bas Tolhuis, Marleen Blom, Ron M. Kerkhoven, Ludo Pagie, Hans Teunissen, Marja Nieuwland, Marieke Simonis, Wouter de Laat, Maarten van Lohuizen, Bas van Steensel

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1001343

Histidine Protects Against Zinc and Nickel Toxicity in Caenorhabditis elegans

John T. Murphy, Janelle J. Bruinsma, Daniel L. Schneider, Sara Collier, James Guthrie, Asif Chinwalla, J. David Robertson, Elaine R. Mardis, Kerry Kornfeld

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1002013

Genetic Regulation by NLA and MicroRNA827 for Maintaining Nitrate-Dependent Phosphate Homeostasis in Arabidopsis

Surya Kant, Mingsheng Peng, Steven J. Rothstein

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1002021

Whole-Exome Re-Sequencing in a Family Quartet Identifies POP1 Mutations As the Cause of a Novel Skeletal Dysplasia

Evgeny A. Glazov, Andreas Zankl, Marina Donskoi, Tony J. Kenna, Gethin P. Thomas, Graeme R. Clark, Emma L. Duncan, Matthew A. Brown

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1002027

Ultra-Deep Sequencing of Mouse Mitochondrial DNA: Mutational Patterns and Their Origins

Adam Ameur, James B. Stewart, Christoph Freyer, Erik Hagström, Max Ingman, Nils-Göran Larsson, Ulf Gyllensten

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1002028

Roles of the Espin Actin-Bundling Proteins in the Morphogenesis and Stabilization of Hair Cell Stereocilia Revealed in CBA/CaJ Congenic Jerker Mice

Gabriella Sekerková, Claus-Peter Richter, James R. Bartles

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1002032

Environmental Sex Determination in the Branchiopod Crustacean Daphnia magna: Deep Conservation of a Doublesex Gene in the Sex-Determining Pathway

Yasuhiko Kato, Kaoru Kobayashi, Hajime Watanabe, Taisen Iguchi

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1001345

Dopamine Signalling in Mushroom Bodies Regulates Temperature-Preference Behaviour in Drosophila

Sunhoe Bang, Seogang Hyun, Sung-Tae Hong, Jongkyun Kang, Kyunghwa Jeong, Joong-Jean Park, Joonho Choe, Jongkyeong Chung

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1001346

Uncoupling Antisense-Mediated Silencing and DNA Methylation in the Imprinted Gnas Cluster

Christine M. Williamson, Simon T. Ball, Claire Dawson, Stuti Mehta, Colin V. Beechey, Martin Fray, Lydia Teboul, T. Neil Dear, Gavin Kelsey, Jo Peters

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1001347

Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegans

Johan Jeong, Jamie M. Verheyden, Judith Kimble

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1001348

A Role for Set1/MLL-Related Components in Epigenetic Regulation of the Caenorhabditis elegans Germ Line

Tengguo Li, William G. Kelly

PLOS Genetics: published March 24, 2011 | https://doi.org/10.1371/journal.pgen.1001349

Systematic Detection of Polygenic cis-Regulatory Evolution

Hunter B. Fraser, Tomas Babak, John Tsang, Yiqi Zhou, Bin Zhang, Margarete Mehrabian, Eric E. Schadt

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1002023

A Tradeoff Drives the Evolution of Reduced Metal Resistance in Natural Populations of Yeast

Shang-Lin Chang, Jun-Yi Leu

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1002034

Limited dCTP Availability Accounts for Mitochondrial DNA Depletion in Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)

Emiliano González-Vioque, Javier Torres-Torronteras, Antoni L. Andreu, Ramon Martí

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1002035

c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases

Eric Bordeleau, Louis-Charles Fortier, François Malouin, Vincent Burrus

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1002039

REVEILLE8 and PSEUDO-REPONSE REGULATOR5 Form a Negative Feedback Loop within the Arabidopsis Circadian Clock

Reetika Rawat, Nozomu Takahashi, Polly Yingshan Hsu, Matthew A. Jones, Jacob Schwartz, Michelle R. Salemi, Brett S. Phinney, Stacey L. Harmer

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001350

Cancer-Associated Splicing Variant of Tumor Suppressor AIMP2/p38: Pathological Implication in Tumorigenesis

Jin Woo Choi, Dae Gyu Kim, Al-Eum Lee, Hye Rim Kim, Jin Young Lee, Nam Hoon Kwon, Young Kee Shin, Soon-Kyung Hwang, Seung-Hee Chang, Myung-Haing Cho, Yoon-La Choi, Jhingook Kim, Seung Hyun Oh, Bora Kim, Soo-Youl Kim, Hyo-Sung Jeon, Jae Yong Park, Hyunseok Peter Kang, Bum Joon Park, Jung Min Han, Sunghoon Kim

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001351

Ancestral Mutation in Telomerase Causes Defects in Repeat Addition Processivity and Manifests As Familial Pulmonary Fibrosis

Jonathan K. Alder, Joy D. Cogan, Andrew F. Brown, Collin J. Anderson, William E. Lawson, Peter M. Lansdorp, John A. Phillips III, James E. Loyd, Julian J.-L. Chen, Mary Armanios

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001352

H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation

Benoit Guillemette, Paul Drogaris, Hsiu-Hsu Sophia Lin, Harry Armstrong, Kyoko Hiragami-Hamada, Axel Imhof, Éric Bonneil, Pierre Thibault, Alain Verreault, Richard J. Festenstein

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001354

The SUMO Isopeptidase Ulp2p Is Required to Prevent Recombination-Induced Chromosome Segregation Lethality following DNA Replication Stress

Ming-Ta Lee, Abla A. Bakir, Kristen N. Nguyen, Jeff Bachant

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001355

Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis

Hector Alvarez, Joanna Opalinska, Li Zhou, Davendra Sohal, Melissa J. Fazzari, Yiting Yu, Christina Montagna, Elizabeth A. Montgomery, Marcia Canto, Kerry B. Dunbar, Jean Wang, Juan Carlos Roa, Yongkai Mo, Tushar Bhagat, K. H. Ramesh, Linda Cannizzaro, J. Mollenhauer, Reid F. Thompson, Masako Suzuki, Stephen Meltzer, Ari Melnick, John M. Greally, Anirban Maitra, Amit Verma

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001356

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Adriana Rodríguez-Marí, Catherine Wilson, Tom A. Titus, Cristian Cañestro, Ruth A. BreMiller, Yi-Lin Yan, Indrajit Nanda, Adam Johnston, John P. Kanki, Erin M. Gray, Xinjun He, Jan Spitsbergen, Detlev Schindler, John H. Postlethwait

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001357

ARGONAUTE10 and ARGONAUTE1 Regulate the Termination of Floral Stem Cells through Two MicroRNAs in Arabidopsis

Lijuan Ji, Xigang Liu, Jun Yan, Wenming Wang, Rae Eden Yumul, Yun Ju Kim, Thanh Theresa Dinh, Jun Liu, Xia Cui, Binglian Zheng, Manu Agarwal, Chunyan Liu, Xiaofeng Cao, Guiliang Tang, Xuemei Chen

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001358

The Recombinases Rad51 and Dmc1 Play Distinct Roles in DNA Break Repair and Recombination Partner Choice in the Meiosis of Tetrahymena

Rachel A. Howard-Till, Agnieszka Lukaszewicz, Josef Loidl

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001359

The Toll-Like Receptor Gene Family Is Integrated into Human DNA Damage and p53 Networks

Daniel Menendez, Maria Shatz, Kathleen Azzam, Stavros Garantziotis, Michael B. Fessler, Michael A. Resnick

PLOS Genetics: published March 31, 2011 | https://doi.org/10.1371/journal.pgen.1001360

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Female adult of the water flea Daphnia magna.

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**Female adult of the water flea Daphnia magna.**