Neighboring sequences are predictive of splicing regulatory element activity. Shown here are projections of hexamer sequence space in the vicinity of the sequences GAAGAA (left blue circle) and TATATT (right blue circle), with known exonic splicing enhancer and silencers indicated as green and red circles, respectively. (See Stadler et al., e191.)
Image Credit: Created by Michael Stadler, using GraphViz.
Review
Genomic Imprinting in Mammals: Emerging Themes and Established Theories
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020147
Research Articles
Harnessing a High Cargo-Capacity Transposon for Genetic Applications in Vertebrates
PLOS Genetics: published November 10, 2006 | https://doi.org/10.1371/journal.pgen.0020169
Expression Profiling of MAP Kinase–Mediated Meiotic Progression in Caenorhabditis elegans
PLOS Genetics: published November 10, 2006 | https://doi.org/10.1371/journal.pgen.0020174
Selection Acts on DNA Secondary Structures to Decrease Transcriptional Mutagenesis
PLOS Genetics: published November 3, 2006 | https://doi.org/10.1371/journal.pgen.0020176
CAF-1 Is Essential for Heterochromatin Organization in Pluripotent Embryonic Cells
PLOS Genetics: published November 3, 2006 | https://doi.org/10.1371/journal.pgen.0020181
p38 MAPK Regulates Expression of Immune Response Genes and Contributes to Longevity in C. elegans
PLOS Genetics: published November 10, 2006 | https://doi.org/10.1371/journal.pgen.0020183
Recombination Hotspots Flank the Cryptococcus Mating-Type Locus: Implications for the Evolution of a Fungal Sex Chromosome
PLOS Genetics: published November 3, 2006 | https://doi.org/10.1371/journal.pgen.0020184
Selection for Unequal Densities of σ70 Promoter-Like Signals in Different Regions of Large Bacterial Genomes
PLOS Genetics: published November 10, 2006 | https://doi.org/10.1371/journal.pgen.0020185
Virulence Attributes and Hyphal Growth of C. neoformans Are Quantitative Traits and the MATα Allele Enhances Filamentation
PLOS Genetics: published November 17, 2006 | https://doi.org/10.1371/journal.pgen.0020187
Inference of Splicing Regulatory Activities by Sequence Neighborhood Analysis
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020191
Defining Synphenotype Groups in Xenopus tropicalis by Use of Antisense Morpholino Oligonucleotides
PLOS Genetics: published November 17, 2006 | https://doi.org/10.1371/journal.pgen.0020193
The Role of DNA Double-Strand Breaks in Spontaneous Homologous Recombination in S. cerevisiae
PLOS Genetics: published November 10, 2006 | https://doi.org/10.1371/journal.pgen.0020194
Four Linked Genes Participate in Controlling Sporulation Efficiency in Budding Yeast
PLOS Genetics: published November 17, 2006 | https://doi.org/10.1371/journal.pgen.0020195
Functional Identification of Api5 as a Suppressor of E2F-Dependent Apoptosis In Vivo
PLOS Genetics: published November 17, 2006 | https://doi.org/10.1371/journal.pgen.0020196
Pigment Pattern in jaguar/obelix Zebrafish Is Caused by a Kir7.1 Mutation: Implications for the Regulation of Melanosome Movement
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020197
Operon Conservation and the Evolution of trans-Splicing in the Phylum Nematoda
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020198
Genomic Variation in Rice: Genesis of Highly Polymorphic Linkage Blocks during Domestication
PLOS Genetics: published November 17, 2006 | https://doi.org/10.1371/journal.pgen.0020199
Temporal Analysis of Meiotic DNA Double-Strand Break Formation and Repair in Drosophila Females
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020200
Opposite Root Growth Phenotypes of hy5 versus hy5 hyh Mutants Correlate with Increased Constitutive Auxin Signaling
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020202
Impact of Nonsense-Mediated mRNA Decay on the Global Expression Profile of Budding Yeast
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020203
Genomic Selective Constraints in Murid Noncoding DNA
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020204
Correspondence
Alternative Splicing at NAGNAG Acceptors: Simply Noise or Noise and More?
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020207
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Authors' Reply
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020208
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Correction
Correction: Evidence for Diversity in Transcriptional Profiles of Single Hematopoietic Stem Cells
PLOS Genetics: published November 24, 2006 | https://doi.org/10.1371/journal.pgen.0020201