Scanning EM micrograph of a Caenorhabditis elegans wild-type adult. Research reported by Brock et al. It describes a novel nuclear hormone receptor that regulates transcription of fatty acid desaturase genes in C. elegans. This regulation is necessary to maintain optimal membrane fatty acid composition.
Image Credit: EM micrograph and false coloring by Trisha J. Brock.
Reviews
Modeling Chromosomes in Mouse to Explore the Function of Genes, Genomic Disorders, and Chromosomal Organization
PLOS Genetics: published July 14, 2006 | https://doi.org/10.1371/journal.pgen.0020086
Matrix-Assisted Laser Desorption/Ionisation, Time-of-Flight Mass Spectrometry in Genomics Research
PLOS Genetics: published July 28, 2006 | https://doi.org/10.1371/journal.pgen.0020100
Research Articles
Two Membrane-Associated Tyrosine Phosphatase Homologs Potentiate C. elegans AKT-1/PKB Signaling
PLOS Genetics: published July 7, 2006 | https://doi.org/10.1371/journal.pgen.0020099
Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination
PLOS Genetics: published July 7, 2006 | https://doi.org/10.1371/journal.pgen.0020101
Neofunctionalization in Vertebrates: The Example of Retinoic Acid Receptors
PLOS Genetics: published July 14, 2006 | https://doi.org/10.1371/journal.pgen.0020102
E. coli Microcosms Indicate a Tight Link between Predictability of Ecosystem Dynamics and Diversity
PLOS Genetics: published July 14, 2006 | https://doi.org/10.1371/journal.pgen.0020103
Possible Ancestral Structure in Human Populations
PLOS Genetics: published July 28, 2006 | https://doi.org/10.1371/journal.pgen.0020105
Potent Induction of Arabidopsis thaliana Flowering by Elevated Growth Temperature
PLOS Genetics: published July 7, 2006 | https://doi.org/10.1371/journal.pgen.0020106
Lymphotoxin-α Gene and Risk of Myocardial Infarction in 6,928 Cases and 2,712 Controls in the ISIS Case-Control Study
PLOS Genetics: published July 7, 2006 | https://doi.org/10.1371/journal.pgen.0020107
Genetic Regulation of Unsaturated Fatty Acid Composition in C. elegans
PLOS Genetics: published July 14, 2006 | https://doi.org/10.1371/journal.pgen.0020108
The Ancestral Eutherian Karyotype Is Present in Xenarthra
PLOS Genetics: published July 21, 2006 | https://doi.org/10.1371/journal.pgen.0020109
Drosophila CENP-A Mutations Cause a BubR1- Dependent Early Mitotic Delay without Normal Localization of Kinetochore Components
PLOS Genetics: published July 14, 2006 | https://doi.org/10.1371/journal.pgen.0020110
In Vivo Robustness Analysis of Cell Division Cycle Genes in Saccharomyces cerevisiae
PLOS Genetics: published July 14, 2006 | https://doi.org/10.1371/journal.pgen.0020111
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Structural Model Analysis of Multiple Quantitative Traits
PLOS Genetics: published July 21, 2006 | https://doi.org/10.1371/journal.pgen.0020114
Transcriptional Profiling of Aging in Human Muscle Reveals a Common Aging Signature
PLOS Genetics: published July 21, 2006 | https://doi.org/10.1371/journal.pgen.0020115
Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations
PLOS Genetics: published July 21, 2006 | https://doi.org/10.1371/journal.pgen.0020116
Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development
PLOS Genetics: published July 28, 2006 | https://doi.org/10.1371/journal.pgen.0020117
Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs
PLOS Genetics: published July 28, 2006 | https://doi.org/10.1371/journal.pgen.0020119
Who Ate Whom? Adaptive Helicobacter Genomic Changes That Accompanied a Host Jump from Early Humans to Large Felines
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PLOS Genetics: published July 28, 2006 | https://doi.org/10.1371/journal.pgen.0020121
Correction
Correction: The Life-Cycle of Operons
PLOS Genetics: published July 28, 2006 | https://doi.org/10.1371/journal.pgen.0020126