Shown here is the expression of a multi-copy myo-3::GFP transgene in a SynMuv B mutant treated with and without NAi of a SynMuv suppressor gene in Caenorhabditis elegans (left and right, respectively). Multiple chromatin remodeling complexes are shown to antagonize the Class B SynMuv genes in regulating gene expression (see Cui et al.).
Image Credit: Photograph and false coloring by Mingxue Cui.
Interview
Willing to Do the Math: An Interview with David Botstein
PLOS Genetics: published May 26, 2006 | https://doi.org/10.1371/journal.pgen.0020079
Research Articles
The Polycomb Group Protein EED Is Dispensable for the Initiation of Random X-Chromosome Inactivation
PLOS Genetics: published May 5, 2006 | https://doi.org/10.1371/journal.pgen.0020066
Coverage and Characteristics of the Affymetrix GeneChip Human Mapping 100K SNP Set
PLOS Genetics: published May 5, 2006 | https://doi.org/10.1371/journal.pgen.0020067
Discordance of Species Trees with Their Most Likely Gene Trees
PLOS Genetics: published May 26, 2006 | https://doi.org/10.1371/journal.pgen.0020068
Risk Alleles of USF1 Gene Predict Cardiovascular Disease of Women in Two Prospective Studies
PLOS Genetics: published May 12, 2006 | https://doi.org/10.1371/journal.pgen.0020069
High-Resolution Recombination Patterns in a Region of Human Chromosome 21 Measured by Sperm Typing
PLOS Genetics: published May 5, 2006 | https://doi.org/10.1371/journal.pgen.0020070
Epigenetic Telomere Protection by Drosophila DNA Damage Response Pathways
PLOS Genetics: published May 19, 2006 | https://doi.org/10.1371/journal.pgen.0020071
Genome-Wide Mapping of Susceptibility to Coronary Artery Disease Identifies a Novel Replicated Locus on Chromosome 17
PLOS Genetics: published May 19, 2006 | https://doi.org/10.1371/journal.pgen.0020072
The Leukocyte Receptor Complex in Chicken Is Characterized by Massive Expansion and Diversification of Immunoglobulin-Like Loci
PLOS Genetics: published May 12, 2006 | https://doi.org/10.1371/journal.pgen.0020073
Diverse Chromatin Remodeling Genes Antagonize the Rb-Involved SynMuv Pathways in C. elegans
PLOS Genetics: published May 19, 2006 | https://doi.org/10.1371/journal.pgen.0020074
Genome Sequence of Rickettsia bellii Illuminates the Role of Amoebae in Gene Exchanges between Intracellular Pathogens
PLOS Genetics: published May 12, 2006 | https://doi.org/10.1371/journal.pgen.0020076
Origination of an X-Linked Testes Chimeric Gene by Illegitimate Recombination in Drosophila
PLOS Genetics: published May 19, 2006 | https://doi.org/10.1371/journal.pgen.0020077
Changes in Gene Expression Foreshadow Diet-Induced Obesity in Genetically Identical Mice
PLOS Genetics: published May 26, 2006 | https://doi.org/10.1371/journal.pgen.0020081