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PLoS Genetics Issue Image | Vol. 9(4) April 2013

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Steroid synthesis regulation: SUMO, Ftz-f1, Scavenger Receptors, and lipids meet in the ring gland

This confocal image shows a wild type Drosophila melanogaster ring gland. This gland is responsible for the synthesis of the steroid hormone ecdysone, which controls animal growth and development. In this issue, Talamillo and coworkers report that the capture of lipids by the ring gland, which are necessary for the synthesis of the hormone, depends on the ubiquitin-like SUMO protein, the nuclear hormone receptor Ftz-f1, and the Scavenger Receptor Snmp1. The nuclei of the gland are marked with DAPI (blue) and the cell contours are marked by phalloidin (red). The image has been mirror-duplicated.

Image Credit: Ana Talamillo and Rosa Barrio, CIC bioGUNE

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Steroid synthesis regulation: SUMO, Ftz-f1, Scavenger Receptors, and lipids meet in the ring gland

This confocal image shows a wild type Drosophila melanogaster ring gland. This gland is responsible for the synthesis of the steroid hormone ecdysone, which controls animal growth and development. In this issue, Talamillo and coworkers report that the capture of lipids by the ring gland, which are necessary for the synthesis of the hormone, depends on the ubiquitin-like SUMO protein, the nuclear hormone receptor Ftz-f1, and the Scavenger Receptor Snmp1. The nuclei of the gland are marked with DAPI (blue) and the cell contours are marked by phalloidin (red). The image has been mirror-duplicated.

Image Credit: Ana Talamillo and Rosa Barrio, CIC bioGUNE

https://doi.org/10.1371/image.pgen.v09.i04.g001