KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype

Petr Kasparek; Zuzana Ileninova; Olga Zbodakova; Ivan Kanchev; Oldrich Benada; Karel Chalupsky; Maria Brattsand; Inken M. Beck; Radislav Sedlacek

doi:10.1371/journal.pgen.1006566

Loading metrics

Open Access

Peer-reviewed

Research Article

KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype

Petr Kasparek,

Affiliations Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic, Faculty of Sciences, Charles University in Prague, Prague, Czech Republic
⨯
Zuzana Ileninova,

Affiliation Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic
⨯
Olga Zbodakova,

Affiliation Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic

http://orcid.org/0000-0003-0188-1324

⨯
Ivan Kanchev,

Affiliation Czech Centre for Phenogenomics, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic
⨯
Oldrich Benada,

Affiliation Laboratory of Molecular Structure Characterization, Institute of Microbiology of the Czech Academy of Sciences, v.v.i., Prague, Czech Republic
⨯
Karel Chalupsky,

Affiliations Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic, Czech Centre for Phenogenomics, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic
⨯
Maria Brattsand,

Affiliation Department of Medical Biosciences, Pathology, Umea University, Umea, Sweden
⨯
Inken M. Beck,

Affiliation Czech Centre for Phenogenomics, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic
⨯
Radislav Sedlacek

* E-mail: radislav.sedlacek@img.cas.cz

Affiliations Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic, Czech Centre for Phenogenomics, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic

http://orcid.org/0000-0002-3352-392X

⨯

KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype

Petr Kasparek,
Zuzana Ileninova,
Olga Zbodakova,
Ivan Kanchev,
Oldrich Benada,
Karel Chalupsky,
Maria Brattsand,
Inken M. Beck,
Radislav Sedlacek

Published: January 17, 2017
https://doi.org/10.1371/journal.pgen.1006566

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Epidermis
Is the Subject Area "Epidermis" applicable to this article?

Thanks for your feedback.
Hair
Is the Subject Area "Hair" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Proteases
Is the Subject Area "Proteases" applicable to this article?

Thanks for your feedback.
Neonates
Is the Subject Area "Neonates" applicable to this article?

Thanks for your feedback.
Phenotypes
Is the Subject Area "Phenotypes" applicable to this article?

Thanks for your feedback.
Vibrissae
Is the Subject Area "Vibrissae" applicable to this article?

Thanks for your feedback.