Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori

Hiroki Sakai; Megumi Sumitani; Yasuhiko Chikami; Kensuke Yahata; Keiro Uchino; Takashi Kiuchi; Susumu Katsuma; Fugaku Aoki; Hideki Sezutsu; Masataka G. Suzuki

doi:10.1371/journal.pgen.1006203

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Research Article

Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori

Hiroki Sakai ,

Contributed equally to this work with: Hiroki Sakai, Megumi Sumitani

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba 277-8562, Japan
⨯
Megumi Sumitani ,

Contributed equally to this work with: Hiroki Sakai, Megumi Sumitani

Affiliation Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), Owashi, Tsukuba, Ibaraki 305-8634, Japan
⨯
Yasuhiko Chikami,

Affiliation Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
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Kensuke Yahata,

Affiliation Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan
⨯
Keiro Uchino,

Affiliation Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), Owashi, Tsukuba, Ibaraki 305-8634, Japan
⨯
Takashi Kiuchi,

Affiliation Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
⨯
Susumu Katsuma,

Affiliation Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan
⨯
Fugaku Aoki,

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba 277-8562, Japan
⨯
Hideki Sezutsu,

Affiliation Transgenic Silkworm Research Unit, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), Owashi, Tsukuba, Ibaraki 305-8634, Japan
⨯
Masataka G. Suzuki

* E-mail: gakyo@k.u-tokyo.ac.jp

Affiliation Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba 277-8562, Japan
⨯

Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm, Bombyx mori

Hiroki Sakai,
Megumi Sumitani,
Yasuhiko Chikami,
Kensuke Yahata,
Keiro Uchino,
Takashi Kiuchi,
Susumu Katsuma,
Fugaku Aoki,
Hideki Sezutsu,
Masataka G. Suzuki

Published: August 31, 2016
https://doi.org/10.1371/journal.pgen.1006203

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