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Open Access
Peer-reviewed
Research Article
Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model
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Petra Füger ,
Contributed equally to this work with: Petra Füger, Vrinda Sreekumar, Rebecca Schüle, Jeannine V. Kern
Affiliations Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany
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Vrinda Sreekumar ,
Contributed equally to this work with: Petra Füger, Vrinda Sreekumar, Rebecca Schüle, Jeannine V. Kern
Affiliations Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany, German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
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Rebecca Schüle ,
Contributed equally to this work with: Petra Füger, Vrinda Sreekumar, Rebecca Schüle, Jeannine V. Kern
Affiliation Hertie-Institute for Clinical Brain Research and Center for Neurology, Department of Neurodegenerative Disease, University of Tübingen, Tübingen, Germany
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Jeannine V. Kern ,
Contributed equally to this work with: Petra Füger, Vrinda Sreekumar, Rebecca Schüle, Jeannine V. Kern
Affiliation Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
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Doychin T. Stanchev,
Affiliation Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
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Carola D. Schneider,
Affiliations Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, Graduate School of Cellular and Molecular Neuroscience, University of Tübingen, Tübingen, Germany
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Kathrin N. Karle,
Affiliation Hertie-Institute for Clinical Brain Research and Center for Neurology, Department of Neurodegenerative Disease, University of Tübingen, Tübingen, Germany
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Katharina J. Daub,
Affiliation Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
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Vera K. Siegert,
Affiliations Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany, Hertie-Institute for Clinical Brain Research and Center for Neurology, Department of Neurodegenerative Disease, University of Tübingen, Tübingen, Germany
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Matthias Flötenmeyer,
Affiliation Max Planck Institute for Developmental Biology, Tübingen, Germany
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Heinz Schwarz,
Affiliation Max Planck Institute for Developmental Biology, Tübingen, Germany
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Ludger Schöls,
Affiliations German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany, Hertie-Institute for Clinical Brain Research and Center for Neurology, Department of Neurodegenerative Disease, University of Tübingen, Tübingen, Germany
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Tobias M. Rasse
* E-mail: tobias.rasse@uni-tuebingen.de
Affiliation Junior Research Group Synaptic Plasticity, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
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Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model
- Petra Füger,
- Vrinda Sreekumar,
- Rebecca Schüle,
- Jeannine V. Kern,
- Doychin T. Stanchev,
- Carola D. Schneider,
- Kathrin N. Karle,
- Katharina J. Daub,
- Vera K. Siegert,
- Matthias Flötenmeyer
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- Published: November 29, 2012
- https://doi.org/10.1371/journal.pgen.1003066