About the Authors

Brian J. Bennett

Current address: University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, United States of America

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Richard C. Davis

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Mete Civelek

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Luz Orozco

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Judy Wu

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Hannah Qi

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Calvin Pan

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

René R. Sevag Packard

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Eleazar Eskin

Affiliation Department of Computer Science, University of California, Los Angeles, Los Angeles, California, United States of America

Mujing Yan

Affiliation Department of Cardiovascular Drug Discovery, Bristol-Myers Squibb, Princeton, New Jersey, United States of America

Todd Kirchgessner

Affiliation Department of Cardiovascular Drug Discovery, Bristol-Myers Squibb, Princeton, New Jersey, United States of America

Zeneng Wang

Affiliation Department of Cellular and Molecular Medicine (NC10), Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States of America

Xinmin Li

Affiliation Department of Cellular and Molecular Medicine (NC10), Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States of America

Jill C. Gregory

Affiliation Department of Cellular and Molecular Medicine (NC10), Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States of America

Stanley L. Hazen

Affiliation Department of Cellular and Molecular Medicine (NC10), Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, United States of America

Peter S. Gargalovic

Affiliation Department of Cardiovascular Drug Discovery, Bristol-Myers Squibb, Princeton, New Jersey, United States of America

Aldons J. Lusis

jlusis@mednet.ucla.edu

Affiliation Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

Competing Interests

Authors MY, TK and PSG are employees and shareholders of Bristol-Myers Squibb.

Author Contributions

Conceived and designed the experiments: BJB RCD AJL. Performed the experiments: BJB RCD LO JW HQ RRSP MY ZW XL JCG. Analyzed the data: BJB RCD MC LO CP RRSP EE TK SLH PSG AJL. Contributed reagents/materials/analysis tools: RCD EE TK SLH PSG AJL. Wrote the paper: BJB RCD MC LO CP PSG AJL.