About the Authors

Yuzuru Imai

yzimai@juntendo.ac.jp (YI); nhattori@juntendo.ac.jp (NH); ryosuket@kuhp.kyoto-u.ac.jp (RT)

‡ These authors contributed equally to this work.

Affiliation Department of Research for Parkinson's Disease, Juntendo University Graduate School of Medicine, Tokyo, Japan

Yoshito Kobayashi

‡ These authors contributed equally to this work.

Affiliations Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan

Tsuyoshi Inoshita

Affiliation Department of Research for Parkinson's Disease, Juntendo University Graduate School of Medicine, Tokyo, Japan

Hongrui Meng

Affiliation Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan

Taku Arano

Affiliation Department of Research for Parkinson's Disease, Juntendo University Graduate School of Medicine, Tokyo, Japan

Kengo Uemura

Affiliation Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Takeshi Asano

Affiliation Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

Kenji Yoshimi

Affiliation Department of Neurophysiology, Juntendo University Graduate School of Medicine, Tokyo, Japan

Chang-Liang Zhang

Affiliations Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan

Gen Matsumoto

Affiliation Department of Neuroscience for Neurodegenerative Disorders, Juntendo University Graduate School of Medicine, Tokyo, Japan

Toshiyuki Ohtsuka

Affiliation Department of Cell Biology, Institute for Virus Research, Kyoto University, Kyoto, Japan

Ryoichiro Kageyama

Affiliation Department of Cell Biology, Institute for Virus Research, Kyoto University, Kyoto, Japan

Hiroshi Kiyonari

Affiliation Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology, Kobe, Japan

Go Shioi

Affiliation Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology, Kobe, Japan

Nobuyuki Nukina

Affiliation Department of Neuroscience for Neurodegenerative Disorders, Juntendo University Graduate School of Medicine, Tokyo, Japan

Nobutaka Hattori

yzimai@juntendo.ac.jp (YI); nhattori@juntendo.ac.jp (NH); ryosuket@kuhp.kyoto-u.ac.jp (RT)

Affiliations Department of Research for Parkinson's Disease, Juntendo University Graduate School of Medicine, Tokyo, Japan, CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan, Research Institute for Diseases of Old Age, Juntendo University Graduate School of Medicine, Tokyo, Japan, Department of Neuroscience for Neurodegenerative Disorders, Juntendo University Graduate School of Medicine, Tokyo, Japan, Department of Neurology, Juntendo University Graduate School of Medicine, Tokyo, Japan

Ryosuke Takahashi

yzimai@juntendo.ac.jp (YI); nhattori@juntendo.ac.jp (NH); ryosuket@kuhp.kyoto-u.ac.jp (RT)

Affiliations Department of Neurology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, CREST (Core Research for Evolutionary Science and Technology), Japan Science and Technology Agency, Saitama, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YI YK KU RT. Performed the experiments: YI YK TI HM TAr TAs KY CLZ. Analyzed the data: YI YK KU NH RT. Contributed reagents/materials/analysis tools: TO RK GM HK GS NN. Wrote the paper: YI YK NH RT.