About the Authors

Mia M. Gaudet

Contributed equally to this work with: Mia M. Gaudet, Karoline B. Kuchenbaecker

Affiliation Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, United States of America

Karoline B. Kuchenbaecker

Contributed equally to this work with: Mia M. Gaudet, Karoline B. Kuchenbaecker

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Joseph Vijai

Affiliation Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Robert J. Klein

Affiliation Program in Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Tomas Kirchhoff

Affiliation Division of Epidemiology, Department of Environmental Medicine, New York University School of Medicine, New York, New York, United States of America

Lesley McGuffog

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Daniel Barrowdale

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Alison M. Dunning

Affiliation Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom

Andrew Lee

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Joe Dennis

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Sue Healey

Affiliation Genetics and Population Health Division, Queensland Institute of Medical Research, Brisbane, Australia

Ed Dicks

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Penny Soucy

Affiliation Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Québec City, Québec, Canada

Olga M. Sinilnikova

Affiliations Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon–Centre Léon Bérard, Lyon, France, INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France

Vernon S. Pankratz

Affiliation Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America

Xianshu Wang

Affiliation Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

Ronald C. Eldridge

Affiliation Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America

Daniel C. Tessier

Affiliation Centre d'Innovation Génome Québec et Université McGill, Montreal, Québec, Canada

Daniel Vincent

Affiliation Centre d'Innovation Génome Québec et Université McGill, Montreal, Québec, Canada

Francois Bacot

Affiliation Centre d'Innovation Génome Québec et Université McGill, Montreal, Québec, Canada

Frans B. L. Hogervorst

Affiliation Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands

Susan Peock

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Dominique Stoppa-Lyonnet

Affiliations Institut Curie, Department of Tumour Biology, Paris, France, Institut Curie, INSERM U830, Paris, France, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

KConFab Investigators

Affiliation Kathleen Cuningham Consortium for Research into Familial Breast Cancer–Peter MacCallum Cancer Center, Melbourne, Australia

Paolo Peterlongo

Affiliations Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy, IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy

Rita K. Schmutzler

Affiliation University Hospital of Cologne, Cologne, Germany

Katherine L. Nathanson

Affiliations Abramson Cancer Center, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America, Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Marion Piedmonte

Affiliation Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York, United States of America

Christian F. Singer

Affiliation Department of Obstetrics and Gyncology and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria

Mads Thomassen

Affiliation Department of Clinical Genetics, Odense University Hospital, Odense, Denmark

Ontario Cancer Genetics Network

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada

Thomas v. O. Hansen

Affiliation Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark

Susan L. Neuhausen

Affiliation Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America

Ignacio Blanco

Affiliation Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL–Catalan Institute of Oncology, Barcelona, Spain

Mark H. Greene

Affiliation Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America

Judith Garber

Affiliation Department of Medical Oncology, Dana-Farber/Partners CancerCare, Boston, Massachusetts, United States of America

Jeffrey N. Weitzel

Affiliation Clinical Cancer Genetics (for the City of Hope Clinical Cancer Genetics Community Research Network), City of Hope, Duarte, California, United States of America

Irene L. Andrulis

Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada

David E. Goldgar

Affiliation Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America

Emma D'Andrea

Affiliations Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy, Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, Padua, Italy

Trinidad Caldes

Affiliation Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain

Heli Nevanlinna

Affiliation Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland

Ana Osorio

Affiliations Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain, Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain

Elizabeth J. van Rensburg

Affiliation Department of Genetics, University of Pretoria, Pretoria, South Africa

Adalgeir Arason

Affiliations Department of Pathology, Landspitali University Hospital, Reykjavik, Iceland, BMC, Faculty of Medicine, University of Iceland, Reykjavik, Iceland

Gad Rennert

Affiliation Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine, Haifa, Israel

Ans M. W. van den Ouweland

Affiliation Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands

Annemarie H. van der Hout

Affiliation Department of Genetics, University Medical Center, Groningen University, Groningen, The Netherlands

Carolien M. Kets

Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Cora M. Aalfs

Affiliation Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands

Juul T. Wijnen

Affiliation Department of Human Genetics and Department of Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands

Margreet G. E. M. Ausems

Affiliation Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands

HEBON

Affiliation Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands

EMBRACE

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Debra Frost

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Steve Ellis

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Elena Fineberg

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Radka Platte

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

D. Gareth Evans

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Chris Jacobs

Affiliation Clinical Genetics, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom

Julian Adlard

Affiliation Yorkshire Regional Genetics Service, Leeds, United Kingdom

Marc Tischkowitz

Affiliation Department of Medical Genetics, University of Cambridge, Cambridge, United Kingdom

Mary E. Porteous

Affiliation South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom

Francesca Damiola

Affiliation INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France

GEMO Study Collaborators

Affiliation National Cancer Genetics Network, UNICANCER Genetic Group, France

Lisa Golmard

Affiliation Institut Curie, Department of Tumour Biology, Paris, France

Laure Barjhoux

Affiliation INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France

Michel Longy

Affiliation Cancer Genetics Unit, INSERM U916, Institut Bergonié, Université de Bordeaux, Bordeaux, France

Muriel Belotti

Affiliation Institut Curie, Department of Tumour Biology, Paris, France

Sandra Fert Ferrer

Affiliation Laboratoire de Génétique Chromosomique, Hôtel Dieu Centre Hospitalier, Chambéry, France

Sylvie Mazoyer

Affiliation INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France

Amanda B. Spurdle

Affiliation Genetics and Population Health Division, Queensland Institute of Medical Research, Brisbane, Australia

Siranoush Manoukian

Affiliation Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy

Monica Barile

Affiliation Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy

Maurizio Genuardi

Affiliation Fiorgen Foundation for Pharmacogenomics and Unit of Medical Genetics, Department of Clinical Physiopathology, University of Florence, Florence, Italy

Norbert Arnold

Affiliation University Hospital of Schleswig-Holstein, University Kiel, Kiel, Germany

Alfons Meindl

Affiliation Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University, Munich, Germany

Christian Sutter

Affiliation University of Heidelberg, Heidelberg, Germany

Barbara Wappenschmidt

Affiliation University Hospital of Cologne, Cologne, Germany

Susan M. Domchek

Affiliation Abramson Cancer Center, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Georg Pfeiler

Affiliation Department of Obstetrics and Gyncology and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria

Eitan Friedman

Affiliation Sheba Medical Center, Tel Aviv, Israel

Uffe Birk Jensen

Affiliation Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark

Mark Robson

Affiliation Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Sohela Shah

Affiliation Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Conxi Lazaro

Affiliation Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL–Catalan Institute of Oncology, Barcelona, Spain

Phuong L. Mai

Affiliation Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America

Javier Benitez

Affiliations Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain, Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain

Melissa C. Southey

Affiliation Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia

Marjanka K. Schmidt

Affiliation Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

Peter A. Fasching

Affiliations University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Erlangen, Germany, Department of Medicine, Division of Hematology and Oncology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

Julian Peto

Affiliation London School of Hygiene and Tropical Medicine, London, United Kingdom

Manjeet K. Humphreys

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Qin Wang

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Kyriaki Michailidou

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Elinor J. Sawyer

Affiliation Division of Cancer Studies, NIHR Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust in partnership with King's College London, London, United Kingdom

Barbara Burwinkel

Affiliations Department of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany, Molecular Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany

Pascal Guénel

Affiliations Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, Villejuif, France, University of Paris-Sud, UMR-S 1018, Villejuif, France

Stig E. Bojesen

Affiliation Copenhagen General Population Study and Department of Clinical Biochemistry, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark

Roger L. Milne

Affiliation Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain

Hermann Brenner

Affiliation Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany

Magdalena Lochmann

Affiliation Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University, Munich, Germany

The GENICA Network

Affiliations Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany, University of Tübingen, Tübingen, Germany, Molecular Genetics of Breast Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany, Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Bochum, Germany, Institute and Outpatient Clinic of Occupational Medicine, Saarland University Medical Center and Saarland University Faculty of Medicine, Homburg, Germany, Institute of Pathology, Medical Faculty of the University of Bonn, Bonn, Germany, Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, Bonn, Germany

Kristiina Aittomäki

Affiliation Department of Clinical Genetics, Helsinki University Central Hospital, Helsinki, Finland

Thilo Dörk

Affiliation Department of Obstetrics and Gynecology, Hannover Medical School, Hannover, Germany

Sara Margolin

Affiliation Department of Oncology and Pathology, Karolinska Institute, Stockholm, Sweden

Arto Mannermaa

Affiliations School of Medicine, Institute of Clinical Medicine, Pathology, and Forensic Medicine, Biocenter Kuopio, Cancer Center of Eastern Finland, University of Eastern Finland, Kuopio, Finland, Imaging Center, Department of Clinical Pathology, Kuopio University Hospital, Kuopio, Finland

Diether Lambrechts

Affiliations Vesalius Research Center, VIB, Leuven, Belgium, Laboratory for Translational Genetics, Department of Oncology, University of Leuven, Belgium

Jenny Chang-Claude

Affiliation Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Paolo Radice

Affiliations Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy, IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy

Graham G. Giles

Affiliations Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, Australia, Centre for Molecular, Environmental, Genetic, and Analytic Epidemiology, The University of Melbourne, Melbourne, Australia

Christopher A. Haiman

Affiliation Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America

Robert Winqvist

Affiliation Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Genetics and Biocenter Oulu, University of Oulu, Oulu University Hospital, Oulu, Finland

Peter Devillee

Affiliation Department of Human Genetics and Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands

Montserrat García-Closas

Affiliations Division of Genetics and Epidemiology and Division of Breast Cancer Research, The Institute of Cancer Research, Sutton, United Kingdom, Division of Breast Cancer Research, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom

Nils Schoof

Affiliation Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Maartje J. Hooning

Affiliation Department of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands

Angela Cox

Affiliation CRUK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield, United Kingdom

Paul D. P. Pharoah

Affiliations Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom

Anna Jakubowska

Affiliation Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland

Nick Orr

Affiliation Division of Breast Cancer Research, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom

Anna González-Neira

Affiliation Human Genotyping–CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre [CNIO], Madrid, Spain

Guillermo Pita

Affiliation Human Genotyping–CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre [CNIO], Madrid, Spain

M. Rosario Alonso

Affiliation Human Genotyping–CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre [CNIO], Madrid, Spain

Per Hall

Affiliation Division of Breast Cancer Research, Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, United Kingdom

Fergus J. Couch

Affiliations Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America

Jacques Simard

Affiliation Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Québec City, Québec, Canada

David Altshuler

Affiliations Department of Molecular Biology and Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Departments of Genetics and Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

Douglas F. Easton

Affiliations Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom, Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom

Georgia Chenevix-Trench

Affiliation Genetics and Population Health Division, Queensland Institute of Medical Research, Brisbane, Australia

Antonis C. Antoniou

Affiliation Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom

Kenneth Offit

offitk@mskcc.org

Affiliation Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: P Hall, FJ Couch, J Simard, D Altshuler, DF Easton, G Chenevix-Trench, AC Antoniou, K Offit. Performed the experiments: MM Gaudet, KB Kuchenbaecker, J Vijai, RJ Klein, T Kirchhoff. Analyzed the data: MM Gaudet, KB Kuchenbaecker, J Vijai, RJ Klein, L McGuffog, D Barrowdale, AM Dunning, J Simard, D Altshuler, DF Easton, AC Antoniou, K Offit. Contributed reagents/materials/analysis tools: L McGuffog, D Barrowdale, AM Dunning, A Lee, J Dennis, S Healey, E Dicks, P Soucy, OM Sinilnikova, VS Pankratz, X Wang, RC Eldridge, DC Tessier, D Vincent, F Bacot, FBL Hogervorst, S Peock, D Stoppa-Lyonnet, P Peterlongo, RK Schmutzler, KL Nathanson, M Piedmonte, CF Singer, M Thomassen, TvO Hansen, SL Neuhausen, I Blanco, MH Greene, J Garber, JN Weitzel, IL Andrulis, DE Goldgar, E D'Andrea, T Caldes, H Nevanlinna, A Osorio, EJ van Rensburg, A Arason, G Rennert, AMW van den Ouweland, AH van der Hout, CM Kets, CM Aalfs, JT Wijnen, MGEM Ausems, D Frost, S Ellis, E Fineberg, R Platte, DG Evans, C Jacobs, J Adlard, M Tischkowitz, ME Porteous, F Damiola, L Golmard, L Barjhoux, M Longy, M Belotti, SF Ferrer, S Mazoyer, AB Spurdle, S Manoukian, M Barile, M Genuardi, N Arnold, A Meindl, C Sutter, B Wappenschmidt, SM Domchek, G Pfeiler, E Friedman, UB Jensen, M Robson, S Shah, C Lazaro, PL Mai, J Benitez, MC Southey, MK Schmidt, PA Fasching, J Peto, MK Humphreys, Q Wang, K Michailidou, EJ Sawyer, B Burwinkel, P Guénel, SE Bojesen, RL Milne, H Brenner, M Lochmann, K Aittomäki, T Dörk, S Margolin, A Mannermaa, D Lambrechts, J Chang-Claude, P Radice, GG Giles, CA Haiman, R Winqvist, P Devillee, M García-Closas, N Schoof, MJ Hooning, A Cox, PDP Pharoah, A Jakubowska, N Orr, A González-Neira, G Pita, MR Alonso, P Hall, FJ Couch, DF Easton, G Chenevix-Trench, AC Antoniou, K Offit. Wrote the paper: MM Gaudet, KB Kuchenbaecker, J Vijai, RJ Klein, AC Antoniou, K Offit.