As PLOS Biology turns 20 years old, we are celebrating two decades of publishing high-impact life sciences research at the forefront of open science. This collection contains articles that look back at landmark PLOS Biology studies and how they have influenced their respective fields, and others that look at how far given fields have come in the past 20 years and where they are going, and others that discuss how publishing and open science have evolved in the past 20 years and what is to come. We will continue to update this collection with content throughout 2023. The image shows a compilation of PLOS Biology cover images from over the years
Image Credit: Masami Overstreet
Editorials
PLOS Biology at 20: Exploring possible futures
PLOS Biology: published October 19, 2023 | https://doi.org/10.1371/journal.pbio.3002377
PLOS Biology at 20: Reflecting on the road we’ve traveled
PLOS Biology: published October 4, 2023 | https://doi.org/10.1371/journal.pbio.3002340
Essays
Open Science 2.0: Towards a truly collaborative research ecosystem
PLOS Biology: published October 19, 2023 | https://doi.org/10.1371/journal.pbio.3002362
Biomedical publishing: Past historic, present continuous, future conditional
PLOS Biology: published October 3, 2023 | https://doi.org/10.1371/journal.pbio.3002234
Perspectives
Authorship practices must evolve to support collaboration and open science
PLOS Biology: published October 13, 2023 | https://doi.org/10.1371/journal.pbio.3002364
Open peer review urgently requires evidence: A call to action
PLOS Biology: published October 4, 2023 | https://doi.org/10.1371/journal.pbio.3002255
A call to implement preclinical study registration in animal ethics review
PLOS Biology: published October 5, 2023 | https://doi.org/10.1371/journal.pbio.3002293
Available upon all requests? How and why we should better incentivize the sharing of biomaterials
PLOS Biology: published October 6, 2023 | https://doi.org/10.1371/journal.pbio.3002360
Primers
Could sexual selection be driven by the mistaken inferences of young females?
PLOS Biology: published October 4, 2023 | https://doi.org/10.1371/journal.pbio.3002321
Related Articles
Metabolic sinkholes: Histones as methyl repositories
PLOS Biology: published October 27, 2023 | https://doi.org/10.1371/journal.pbio.3002371
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Research Articles
Inferred Attractiveness: A generalized mechanism for sexual selection that can maintain variation in traits and preferences over time
PLOS Biology: published October 3, 2023 | https://doi.org/10.1371/journal.pbio.3002269
Related Articles
Genomes from historical Drosophila melanogaster specimens illuminate adaptive and demographic changes across more than 200 years of evolution
PLOS Biology: published October 12, 2023 | https://doi.org/10.1371/journal.pbio.3002333
Evolutionary innovation through transcription factor rewiring in microbes is shaped by levels of transcription factor activity, expression, and existing connectivity
PLOS Biology: published October 23, 2023 | https://doi.org/10.1371/journal.pbio.3002348
Pleiotropic hubs drive bacterial surface competition through parallel changes in colony composition and expansion
PLOS Biology: published October 16, 2023 | https://doi.org/10.1371/journal.pbio.3002338
Abstract perceptual choice signals during action-linked decisions in the human brain
PLOS Biology: published October 10, 2023 | https://doi.org/10.1371/journal.pbio.3002324
Effects of stochastic coding on olfactory discrimination in flies and mice
PLOS Biology: published October 31, 2023 | https://doi.org/10.1371/journal.pbio.3002206
Independent insulin signaling modulators govern hot avoidance under different feeding states
PLOS Biology: published October 17, 2023 | https://doi.org/10.1371/journal.pbio.3002332
Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics
PLOS Biology: published October 4, 2023 | https://doi.org/10.1371/journal.pbio.3002315
Identification of the regulatory circuit governing corneal epithelial fate determination and disease
PLOS Biology: published October 19, 2023 | https://doi.org/10.1371/journal.pbio.3002336
Developmental estrogen exposure in mice disrupts uterine epithelial cell differentiation and causes adenocarcinoma via Wnt/β-catenin and PI3K/AKT signaling
PLOS Biology: published October 19, 2023 | https://doi.org/10.1371/journal.pbio.3002334
Wolbachia endosymbionts manipulate the self-renewal and differentiation of germline stem cells to reinforce fertility of their fruit fly host
PLOS Biology: published October 24, 2023 | https://doi.org/10.1371/journal.pbio.3002335
Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1
PLOS Biology: published October 23, 2023 | https://doi.org/10.1371/journal.pbio.3002337
Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles
PLOS Biology: published October 26, 2023 | https://doi.org/10.1371/journal.pbio.3002339
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Microbial thermogenesis is dependent on ATP concentrations and the protein kinases ArcB, GlnL, and YccC
PLOS Biology: published October 20, 2023 | https://doi.org/10.1371/journal.pbio.3002180
Short Reports
Adiponectin in the mammalian host influences ticks’ acquisition of the Lyme disease pathogen Borrelia
PLOS Biology: published October 20, 2023 | https://doi.org/10.1371/journal.pbio.3002331
Histone methyltransferase activity affects metabolism in human cells independently of transcriptional regulation
PLOS Biology: published October 26, 2023 | https://doi.org/10.1371/journal.pbio.3002354
Related Articles
Mammalian cells internalize bacteriophages and use them as a resource to enhance cellular growth and survival
PLOS Biology: published October 26, 2023 | https://doi.org/10.1371/journal.pbio.3002341
Methods and Resources
Significant decrease of maternal mitochondria carryover using optimized spindle-chromosomal complex transfer
PLOS Biology: published October 5, 2023 | https://doi.org/10.1371/journal.pbio.3002313
A Drosophila glial cell atlas reveals a mismatch between transcriptional and morphological diversity
PLOS Biology: published October 20, 2023 | https://doi.org/10.1371/journal.pbio.3002328
Discovery Reports
Eggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism
PLOS Biology: published October 24, 2023 | https://doi.org/10.1371/journal.pbio.3002342
Multiple light signaling pathways control solar tracking in sunflowers
PLOS Biology: published October 31, 2023 | https://doi.org/10.1371/journal.pbio.3002344