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Table of Contents

April 2016

Cover

Mapping Disease Space to Track Resilience
Issue Image

This study by Torres et al. reveals that infections cause sick hosts to loop through disease space on their return back to health; resilient individuals take tiny loops through this space, minimizing the impact of the infection. The image presents a graph showing the looping relationship of data in a resilient malaria infection tracing the path (clockwise, from top left) from health, through disease, and back to health.

Image Credit: Brenda Torres

Unsolved Mystery

Time Slices: What Is the Duration of a Percept?

Michael H. Herzog, Thomas Kammer, Frank Scharnowski

PLOS Biology: published April 12, 2016 | https://doi.org/10.1371/journal.pbio.1002433

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  1. Correction: Time Slices: What Is the Duration of a Percept?

Perspectives

Farewell to the Lose–Lose Reality of Policing Plant Imports

Dani Zamir

PLOS Biology: published April 19, 2016 | https://doi.org/10.1371/journal.pbio.1002438

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  1. Freeing Crop Genetics through the Open Source Seed Initiative

Reinventing Biostatistics Education for Basic Scientists

Tracey L. Weissgerber, Vesna D. Garovic, Jelena S. Milin-Lazovic, Stacey J. Winham, Zoran Obradovic, Jerome P. Trzeciakowski, Natasa M. Milic

PLOS Biology: published April 8, 2016 | https://doi.org/10.1371/journal.pbio.1002430

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  1. Correction: Reinventing Biostatistics Education for Basic Scientists

Gauging the Purported Costs of Public Data Archiving for Long-Term Population Studies

Simon Robin Evans

PLOS Biology: published April 8, 2016 | https://doi.org/10.1371/journal.pbio.1002432

Community Page

Freeing Crop Genetics through the Open Source Seed Initiative

Claire H. Luby, Irwin L. Goldman

PLOS Biology: published April 19, 2016 | https://doi.org/10.1371/journal.pbio.1002441

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Research Articles

Characterization of Greenbeard Genes Involved in Long-Distance Kind Discrimination in a Microbial Eukaryote

Jens Heller, Jiuhai Zhao, Gabriel Rosenfield, David J. Kowbel, Pierre Gladieux, N. Louise Glass

PLOS Biology: published April 14, 2016 | https://doi.org/10.1371/journal.pbio.1002431

How Many Parameters Does It Take to Describe Disease Tolerance?

Alexander Louie, Kyung Han Song, Alejandra Hotson, Ann Thomas Tate, David S. Schneider

PLOS Biology: published April 18, 2016 | https://doi.org/10.1371/journal.pbio.1002435

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  1. Tracking Resilience to Infections by Mapping Disease Space
  2. Correction: How Many Parameters Does It Take to Describe Disease Tolerance?

Tracking Resilience to Infections by Mapping Disease Space

Brenda Y. Torres, Jose Henrique M. Oliveira, Ann Thomas Tate, Poonam Rath, Katherine Cumnock, David S. Schneider

PLOS Biology: published April 18, 2016 | https://doi.org/10.1371/journal.pbio.1002436

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  1. How Many Parameters Does It Take to Describe Disease Tolerance?
  2. Correction: Tracking Resilience to Infections by Mapping Disease Space

Posterior Parietal Cortex Drives Inferotemporal Activations During Three-Dimensional Object Vision

Ilse C. Van Dromme, Elsie Premereur, Bram-Ernst Verhoef, Wim Vanduffel, Peter Janssen

PLOS Biology: published April 15, 2016 | https://doi.org/10.1371/journal.pbio.1002445

Chromatin Modulatory Proteins and Olfactory Receptor Signaling in the Refinement and Maintenance of Fruitless Expression in Olfactory Receptor Neurons

Catherine E. Hueston, Douglas Olsen, Qingyun Li, Sumie Okuwa, Bo Peng, Jianni Wu, Pelin Cayirlioglu Volkan

PLOS Biology: published April 19, 2016 | https://doi.org/10.1371/journal.pbio.1002443

Connective Auxin Transport in the Shoot Facilitates Communication between Shoot Apices

Tom Bennett, Geneviève Hines, Martin van Rongen, Tanya Waldie, Megan G. Sawchuk, Enrico Scarpella, Karin Ljung, Ottoline Leyser

PLOS Biology: published April 27, 2016 | https://doi.org/10.1371/journal.pbio.1002446

Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold

Roberta Noseda, Marta Guerrero-Valero, Valeria Alberizzi, Stefano C. Previtali, Diane L. Sherman, Marilena Palmisano, Richard L. Huganir, Klaus-Armin Nave, Ana Cuenda, Maria Laura Feltri, Peter J. Brophy, Alessandra Bolino

PLOS Biology: published April 12, 2016 | https://doi.org/10.1371/journal.pbio.1002440

Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice

Sathish K. Murali, Olena Andrukhova, Erica L. Clinkenbeard, Kenneth E. White, Reinhold G. Erben

PLOS Biology: published April 1, 2016 | https://doi.org/10.1371/journal.pbio.1002427

Roles of the TRAPP-II Complex and the Exocyst in Membrane Deposition during Fission Yeast Cytokinesis

Ning Wang, I-Ju Lee, Galen Rask, Jian-Qiu Wu

PLOS Biology: published April 15, 2016 | https://doi.org/10.1371/journal.pbio.1002437

Structural and Molecular Mechanism of CdpR Involved in Quorum-Sensing and Bacterial Virulence in Pseudomonas aeruginosa

Jingru Zhao, Xiang Yu, Miao Zhu, Huaping Kang, Jinbiao Ma, Min Wu, Jianhua Gan, Xin Deng, Haihua Liang

PLOS Biology: published April 27, 2016 | https://doi.org/10.1371/journal.pbio.1002449

Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities

Scott J. Callahan, Yvette A. Luyten, Yogesh K. Gupta, Geoffrey G. Wilson, Richard J. Roberts, Richard D. Morgan, Aneel K. Aggarwal

PLOS Biology: published April 15, 2016 | https://doi.org/10.1371/journal.pbio.1002442

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Meta-Research Article

“One Health” or Three? Publication Silos Among the One Health Disciplines

Kezia R. Manlove, Josephine G. Walker, Meggan E. Craft, Kathryn P. Huyvaert, Maxwell B. Joseph, Ryan S. Miller, Pauline Nol, Kelly A. Patyk, Daniel O’Brien, Daniel P. Walsh, Paul C. Cross

PLOS Biology: published April 21, 2016 | https://doi.org/10.1371/journal.pbio.1002448

Correction

Correction: The Grand Convergence: Closing the Divide between Public Health Funding and Global Health Needs

The PLOS Biology Staff

PLOS Biology: published April 1, 2016 | https://doi.org/10.1371/journal.pbio.1002439

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Formal Comments

Morton, Gould, and Bias: A Comment on “The Mismeasure of Science”

Michael Weisberg, Diane B. Paul

PLOS Biology: published April 19, 2016 | https://doi.org/10.1371/journal.pbio.1002444

Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation

Miguel Mompeán, Avijit Chakrabartty, Emanuele Buratti, Douglas V. Laurents

PLOS Biology: published April 20, 2016 | https://doi.org/10.1371/journal.pbio.1002447