PLZF expression (in red) sustains neural progenitor proliferation and regulates the onset of Neurog2 expression (in blue) and formation of Lhx1/5+ interneurons (in green) in a chick embryo central spinal cord section. See Gaber et al. (e1001676) for more details.
Image Credit: Zachary Gaber and Bennett Novitch
Editorials
A Lot Can Happen in a Decade
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001689
Collection Overview: Ten Years of Wonderful Open Access Science
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001688
Expert Failure: Re-evaluating Research Assessment
PLOS Biology: published October 8, 2013 | https://doi.org/10.1371/journal.pbio.1001677
Related Articles
Synopses
A Sea of Change
PLOS Biology: published October 15, 2013 | https://doi.org/10.1371/journal.pbio.1001683
Related Articles
A Welcome Chink in Drug Resistance
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001693
Related Articles
His Hormone, Her Oogenesis: How Male Malaria Mosquitoes Trigger Female Egg Development
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001694
Related Articles
Building a Sea Urchin on Shifting Sands
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001690
Related Articles
Confirming the Importance of the R-Spine: New Insights into Protein Kinase Regulation
PLOS Biology: published October 15, 2013 | https://doi.org/10.1371/journal.pbio.1001681
Related Articles
Essay
What Can Article-Level Metrics Do for You?
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001687
Perspectives
The Open Access Movement Grows Up: Taking Stock of a Revolution
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001686
Architecting the Future of Research Communication: Building the Models and Analytics for an Open Access Future
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001691
Obituary
A Feeling for the Cell: Christian de Duve (1917–2013)
PLOS Biology: published October 1, 2013 | https://doi.org/10.1371/journal.pbio.1001671
Primer
Cis-Regulatory Timers for Developmental Gene Expression
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001698
Related Articles
Research Articles
Biotic and Human Vulnerability to Projected Changes in Ocean Biogeochemistry over the 21st Century
PLOS Biology: published October 15, 2013 | https://doi.org/10.1371/journal.pbio.1001682
Related Articles
Coevolution and the Effects of Climate Change on Interacting Species
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001685
Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001692
Related Articles
The Assessment of Science: The Relative Merits of Post-Publication Review, the Impact Factor, and the Number of Citations
PLOS Biology: published October 8, 2013 | https://doi.org/10.1371/journal.pbio.1001675
Related Articles
The Interaction between a Sexually Transferred Steroid Hormone and a Female Protein Regulates Oogenesis in the Malaria Mosquito Anopheles gambiae
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001695
Related Articles
A Critical Role for the Hippocampus in the Valuation of Imagined Outcomes
PLOS Biology: published October 22, 2013 | https://doi.org/10.1371/journal.pbio.1001684
PLZF Regulates Fibroblast Growth Factor Responsiveness and Maintenance of Neural Progenitors
PLOS Biology: published October 8, 2013 | https://doi.org/10.1371/journal.pbio.1001676
The Impact of Gene Expression Variation on the Robustness and Evolvability of a Developmental Gene Regulatory Network
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001696
Related Articles
Functional Brachyury Binding Sites Establish a Temporal Read-out of Gene Expression in the Ciona Notochord
PLOS Biology: published October 29, 2013 | https://doi.org/10.1371/journal.pbio.1001697
Related Articles
Identification of a New Stromal Cell Type Involved in the Regulation of Inflamed B Cell Follicles
PLOS Biology: published October 1, 2013 | https://doi.org/10.1371/journal.pbio.1001672
TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function
PLOS Biology: published October 8, 2013 | https://doi.org/10.1371/journal.pbio.1001674
NECAP 1 Regulates AP-2 Interactions to Control Vesicle Size, Number, and Cargo During Clathrin-Mediated Endocytosis
PLOS Biology: published October 1, 2013 | https://doi.org/10.1371/journal.pbio.1001670
Structure of UreG/UreF/UreH Complex Reveals How Urease Accessory Proteins Facilitate Maturation of Helicobacter pylori Urease
PLOS Biology: published October 8, 2013 | https://doi.org/10.1371/journal.pbio.1001678
Deciphering the Structural Basis of Eukaryotic Protein Kinase Regulation
PLOS Biology: published October 15, 2013 | https://doi.org/10.1371/journal.pbio.1001680
Related Articles
Design Principles of the Yeast G1/S Switch
PLOS Biology: published October 1, 2013 | https://doi.org/10.1371/journal.pbio.1001673
eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation
PLOS Biology: published October 15, 2013 | https://doi.org/10.1371/journal.pbio.1001679
An RNA-Binding Complex Involved in Ribosome Biogenesis Contains a Protein with Homology to tRNA CCA-Adding Enzyme
PLOS Biology: published October 1, 2013 | https://doi.org/10.1371/journal.pbio.1001669
Book Review%2FScience in the Media
Seeing an Unseen Science
PLOS Biology: published October 1, 2013 | https://doi.org/10.1371/journal.pbio.1001659