A molecular mechanism involving a protease inhibitor, cystatin NtCYS, and its target, the protease NtCP14, regulate the programmed cell death of the suspensor organ during plant embryogenesis. See Zhao et al. (e1001655) in this issue.
Image Credit: Peng Zhao and Meng-xiang Sun
Synopses
Deep Genealogy and the Dilution of Risk
PLOS Biology: published September 17, 2013 | https://doi.org/10.1371/journal.pbio.1001660
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The Fate of the Plant Embryo's Suspensor: Balancing Life and Death
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001656
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Deacetylation Ensures Timely Regulation of Flowering
PLOS Biology: published September 3, 2013 | https://doi.org/10.1371/journal.pbio.1001646
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Fine-tuning Metabolic Switches
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001664
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Expanding the Regulatory Repertoire of GEFs
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001654
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Up Close and Personal with an Internal-Membrane Virus
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001668
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Perspectives
The Actress, the Court, and What Needs to Be Done to Guarantee the Future of Clinical Genomics
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001663
Spatially Explicit Data: Stewardship and Ethical Challenges in Science
PLOS Biology: published September 3, 2013 | https://doi.org/10.1371/journal.pbio.1001634
Lost Branches on the Tree of Life
PLOS Biology: published September 3, 2013 | https://doi.org/10.1371/journal.pbio.1001636
Obituary
Garniss Curtis (1919–2012): Dating Our Past
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001650
Research Articles
Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study
PLOS Biology: published September 17, 2013 | https://doi.org/10.1371/journal.pbio.1001661
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Unisexual and Heterosexual Meiotic Reproduction Generate Aneuploidy and Phenotypic Diversity De Novo in the Yeast Cryptococcus neoformans
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001653
Brain Systems for Probabilistic and Dynamic Prediction: Computational Specificity and Integration
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001662
A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning
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A Meiosis-Specific Form of the APC/C Promotes the Oocyte-to-Embryo Transition by Decreasing Levels of the Polo Kinase Inhibitor Matrimony
PLOS Biology: published September 3, 2013 | https://doi.org/10.1371/journal.pbio.1001648
A Bipartite Molecular Module Controls Cell Death Activation in the Basal Cell Lineage of Plant Embryos
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001655
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Photoperiodic Regulation of Flowering Time through Periodic Histone Deacetylation of the Florigen Gene FT
PLOS Biology: published September 3, 2013 | https://doi.org/10.1371/journal.pbio.1001649
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Hypoxic Regulation of Hand1 Controls the Fetal-Neonatal Switch in Cardiac Metabolism
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001666
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HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001665
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Dectin-1 Is Essential for Reverse Transcytosis of Glycosylated SIgA-Antigen Complexes by Intestinal M Cells
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Modulation of Global Low-Frequency Motions Underlies Allosteric Regulation: Demonstration in CRP/FNR Family Transcription Factors
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001651
Integrated Conformational and Lipid-Sensing Regulation of Endosomal ArfGEF BRAG2
PLOS Biology: published September 10, 2013 | https://doi.org/10.1371/journal.pbio.1001652
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Mechanism of Membranous Tunnelling Nanotube Formation in Viral Genome Delivery
PLOS Biology: published September 24, 2013 | https://doi.org/10.1371/journal.pbio.1001667
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Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription
PLOS Biology: published September 3, 2013 | https://doi.org/10.1371/journal.pbio.1001647