Common Disease, Multiple Rare (and Distant) Variants

Richard Robinson

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000293

Related Articles

1. Rare Variants Create Synthetic Genome-Wide Associations
2. Rare Variants Create Synthetic Genome-Wide Associations

Evolving Towards Mutualism

Diana Gitig

PLOS Biology: published January 12, 2010 | https://doi.org/10.1371/journal.pbio.1000279

Related Articles

1. Experimental Evolution of a Plant Pathogen into a Legume Symbiont
2. Experimental Evolution of a Plant Pathogen into a Legume Symbiont

Targeting Misfolded Proteins to Fight Neurodegenerative Diseases

Kira Heller

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000290

Related Articles

1. Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease
2. Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease

SATB1 Makes a Splash in T Cell Wnt Signaling

Caitlin Sedwick

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000295

Related Articles

1. Global Regulator SATB1 Recruits β-Catenin and Regulates T_H2 Differentiation in Wnt-Dependent Manner
2. Global Regulator SATB1 Recruits β-Catenin and Regulates T_H2 Differentiation in Wnt-Dependent Manner

The Roles of PINK1 and Parkin in Parkinson's Disease

Rachel Jones

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000299

Related Articles

1. PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
2. PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Quiet and Poised: “Silent” Genes Accumulate Transcription Machinery

Richard Robinson

PLOS Biology: published January 5, 2010 | https://doi.org/10.1371/journal.pbio.1000269

Related Articles

1. Poised Transcription Factories Prime Silent uPA Gene Prior to Activation
2. Poised Transcription Factories Prime Silent uPA Gene Prior to Activation

Evolution of Adaptive Behaviour in Robots by Means of Darwinian Selection

Dario Floreano, Laurent Keller

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000292

University of California Research Seminar Network: A Prospectus

James R. Carey, John Christian Laursen, Steven D. Glaser, Stephen Raphael, Gregory H. Miller, John Crawford, Timothy F. Lane, Patricia J. LiWang, Kimberly Hammond, Theodore Groves, Jean-Francois Pittet, David Stuart, Phokion G. Kolaitis, Laura Serwer, Mengfei Chen, Kenneth Feer

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000289

A Predominantly Neolithic Origin for European Paternal Lineages

Patricia Balaresque, Georgina R. Bowden, Susan M. Adams, Ho-Yee Leung, Turi E. King, Zoë H. Rosser, Jane Goodwin, Jean-Paul Moisan, Christelle Richard, Ann Millward, Andrew G. Demaine, Guido Barbujani, Carlo Previderè, Ian J. Wilson, Chris Tyler-Smith, Mark A. Jobling

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000285

Rare Variants Create Synthetic Genome-Wide Associations

Samuel P. Dickson, Kai Wang, Ian Krantz, Hakon Hakonarson, David B. Goldstein

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000294

Related Articles

1. Common Disease, Multiple Rare (and Distant) Variants
2. Common Disease, Multiple Rare (and Distant) Variants

Ultradeep Sequencing of a Human Ultraconserved Region Reveals Somatic and Constitutional Genomic Instability

Anna De Grassi, Cinzia Segala, Fabio Iannelli, Sara Volorio, Lucio Bertario, Paolo Radice, Loris Bernard, Francesca D. Ciccarelli

PLOS Biology: published January 5, 2010 | https://doi.org/10.1371/journal.pbio.1000275

Experimental Evolution of a Plant Pathogen into a Legume Symbiont

Marta Marchetti, Delphine Capela, Michelle Glew, Stéphane Cruveiller, Béatrice Chane-Woon-Ming, Carine Gris, Ton Timmers, Véréna Poinsot, Luz B. Gilbert, Philipp Heeb, Claudine Médigue, Jacques Batut, Catherine Masson-Boivin

PLOS Biology: published January 12, 2010 | https://doi.org/10.1371/journal.pbio.1000280

Related Articles

1. Evolving Towards Mutualism
2. Evolving Towards Mutualism

Coherence Potentials: Loss-Less, All-or-None Network Events in the Cortex

Tara C. Thiagarajan, Mikhail A. Lebedev, Miguel A. Nicolelis, Dietmar Plenz

PLOS Biology: published January 12, 2010 | https://doi.org/10.1371/journal.pbio.1000278

Related Articles

1. Correction: Coherence Potentials: Loss-Less, All-or-None Network Events in the Cortex
2. Correction: Coherence Potentials: Loss-Less, All-or-None Network Events in the Cortex

Endogenous Nmnat2 Is an Essential Survival Factor for Maintenance of Healthy Axons

Jonathan Gilley, Michael P. Coleman

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000300

Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease

Daniel W. Neef, Michelle L. Turski, Dennis J. Thiele

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000291

Related Articles

1. Targeting Misfolded Proteins to Fight Neurodegenerative Diseases
2. Targeting Misfolded Proteins to Fight Neurodegenerative Diseases

Global Regulator SATB1 Recruits β-Catenin and Regulates T_H2 Differentiation in Wnt-Dependent Manner

Dimple Notani, Kamalvishnu P. Gottimukkala, Ranveer S. Jayani, Amita S. Limaye, Madhujit V. Damle, Sameet Mehta, Prabhat Kumar Purbey, Jomon Joseph, Sanjeev Galande

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000296

Related Articles

1. SATB1 Makes a Splash in T Cell Wnt Signaling
2. SATB1 Makes a Splash in T Cell Wnt Signaling
3. Expression of Concern: Global Regulator SATB1 Recruits β-Catenin and Regulates T_H2 Differentiation in Wnt-Dependent Manner

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka, Der-Fen Suen, Clement A. Gautier, Jie Shen, Mark R. Cookson, Richard J. Youle

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000298

Related Articles

1. The Roles of PINK1 and Parkin in Parkinson's Disease
2. The Roles of PINK1 and Parkin in Parkinson's Disease
3. PINK1: From Parkinson’s disease to mitophagy and back again

Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes

Casper C. Hoogenraad, Ioana Popa, Kensuke Futai, Emma Sanchez-Martinez, Phebe S. Wulf, Thijs van Vlijmen, Bjorn R. Dortland, Viola Oorschot, Roland Govers, Maria Monti, Albert J. R. Heck, Morgan Sheng, Judith Klumperman, Holger Rehmann, Dick Jaarsma, Lukas C. Kapitein, Peter van der Sluijs

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000283

Related Articles

1. Correction: Neuron Specific Rab4 Effector GRASP-1 Coordinates Membrane Specialization and Maturation of Recycling Endosomes

The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins

Rachel Santarella-Mellwig, Josef Franke, Andreas Jaedicke, Matyas Gorjanacz, Ulrike Bauer, Aidan Budd, Iain W. Mattaj, Damien P. Devos

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000281

Related Articles

1. Correction: The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins

A Rho Scaffold Integrates the Secretory System with Feedback Mechanisms in Regulation of Auxin Distribution

Ora Hazak, Daria Bloch, Limor Poraty, Hasana Sternberg, Jing Zhang, Jiří Friml, Shaul Yalovsky

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000282

Origin of Irreversibility of Cell Cycle Start in Budding Yeast

Gilles Charvin, Catherine Oikonomou, Eric D. Siggia, Frederick R. Cross

PLOS Biology: published January 19, 2010 | https://doi.org/10.1371/journal.pbio.1000284

Related Articles

1. Correction: Origin of Irreversibility of Cell Cycle Start in Budding Yeast

CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation

Genevieve M. Vidanes, Frédéric D. Sweeney, Sarah Galicia, Stephanie Cheung, John P. Doyle, Daniel Durocher, David P. Toczyski

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000286

Related Articles

1. A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G₂/M DNA Damage Checkpoint

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G₂/M DNA Damage Checkpoint

Marcel A. T. M. van Vugt, Alexandra K. Gardino, Rune Linding, Gerard J. Ostheimer, H. Christian Reinhardt, Shao-En Ong, Chris S. Tan, Hua Miao, Susan M. Keezer, Jeijin Li, Tony Pawson, Timothy A. Lewis, Steven A. Carr, Stephen J. Smerdon, Thijn R. Brummelkamp, Michael B. Yaffe

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000287

Related Articles

1. CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation

Poised Transcription Factories Prime Silent uPA Gene Prior to Activation

Carmelo Ferrai, Sheila Q. Xie, Paolo Luraghi, Davide Munari, Francisco Ramirez, Miguel R. Branco, Ana Pombo, Massimo P. Crippa

PLOS Biology: published January 5, 2010 | https://doi.org/10.1371/journal.pbio.1000270

Related Articles

1. Quiet and Poised: “Silent” Genes Accumulate Transcription Machinery
2. Quiet and Poised: “Silent” Genes Accumulate Transcription Machinery

Role of Plastid Protein Phosphatase TAP38 in LHCII Dephosphorylation and Thylakoid Electron Flow

Mathias Pribil, Paolo Pesaresi, Alexander Hertle, Roberto Barbato, Dario Leister

PLOS Biology: published January 26, 2010 | https://doi.org/10.1371/journal.pbio.1000288

2-D Structure of the A Region of Xist RNA and Its Implication for PRC2 Association

Sylvain Maenner, Magali Blaud, Laetitia Fouillen, Anne Savoye, Virginie Marchand, Agnès Dubois, Sarah Sanglier-Cianférani, Alain Van Dorsselaer, Philippe Clerc, Philip Avner, Athanase Visvikis, Christiane Branlant

PLOS Biology: published January 5, 2010 | https://doi.org/10.1371/journal.pbio.1000276

Preserving a Space for Science in an Age of Democracy

Harry Collins

PLOS Biology: published January 5, 2010 | https://doi.org/10.1371/journal.pbio.1000274