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May 2009

An article published in the May issue of PLoS Biology reports on the completion of the mouse genome (see Church et al., e1000112). This genome assembly was constructed from a single inbred stain, C57BL/6J (featured in the center of the photo). A more-complete genome assembly reveals not only how mice differ from humans, but also shows how various strains can differ from each other.

Image Credit: Jennifer Torrance (Multimedia Services, The Jackson Laboratory).

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Deanna M. Church, Leo Goodstadt, LaDeana W. Hillier, Michael C. Zody, Steve Goldstein, Xinwe She, Carol J. Bult, Richa Agarwala, Joshua L. Cherry, Michael DiCuccio, Wratko Hlavina, Yuri Kapustin, Peter Meric, Donna Maglott, Zoë Birtle, Ana C. Marques, Tina Graves, Shiguo Zhou, Brian Teague, Konstantinos Potamousis, Christopher Churas, Michael Place, Jill Herschleb, Ron Runnheim, Daniel Forrest, James Amos-Landgraf, David C. Schwartz, Ze Cheng, Kerstin Lindblad-Toh, Evan E. Eichler, Chris P. Ponting, The Mouse Genome Sequencing Consortium

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Mark E. Burkard, John Maciejowski, Verónica Rodriguez-Bravo, Michael Repka, Drew M. Lowery, Karl R. Clauser, Chao Zhang, Kevan M. Shokat, Steven A. Carr, Michael B. Yaffe, Prasad V. Jallepalli

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