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April 2009

An image of rod and cone photoreceptors in the primate retina is divided into several interlocking pieces. As reported in this issue of PLoS Biology (see Gauthier et al., e1000063), retinal ganglion cells perform a similar division of the visual scene represented by the photoreceptors. Each ganglion cell samples from an irregularly shaped region of space. These regions interlock like puzzle pieces to represent completely the images we see.

Image Credit: Jeffrey Gauthier (Salk Institute for Biological Studies).

Essay

How to Make Evolution-Proof Insecticides for Malaria Control

Andrew F Read, Penelope A Lynch, Matthew B Thomas

Research Articles

Accelerated Adaptive Evolution on a Newly Formed X Chromosome

Doris Bachtrog, Jeffrey D Jensen, Zhi Zhang

Reawakening Retrocyclins: Ancestral Human Defensins Active Against HIV-1

Nitya Venkataraman, Amy L Cole, Piotr Ruchala, Alan J Waring, Robert I Lehrer, Olga Stuchlik, Jan Pohl, Alexander M Cole

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Jeffrey L Gauthier, Greg D Field, Alexander Sher, Martin Greschner, Jonathon Shlens, Alan M Litke, E. J Chichilnisky

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Andreas Bergthaler, Lukas Flatz, Admar Verschoor, Ahmed N Hegazy, Martin Holdener, Katja Fink, Bruno Eschli, Doron Merkler, Rami Sommerstein, Edit Horvath, Marylise Fernandez, André Fitsche, Beatrice M Senn, J. Sjef Verbeek, Bernhard Odermatt, Claire-Anne Siegrist, Daniel D Pinschewer

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Structural Studies of the Giant Mimivirus

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Correction

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