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Table of Contents

January 2009

Cover

An infant chimpanzee.
Issue Image

Many of the differences between humans and our closest living relative are likely to be the result of natural selection acting on genes. However, a nonadaptive process unrelated to natural selection may have driven evolution in some of the genes that have changed the most since our common ancestor with chimpanzees (see Berglund et al., e1000026).

Image Credit: Owen Booth

Synopsis

Feedback System Protects Inner Ear

Richard Robinson

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000012

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Essays

Input Subsidies to Improve Smallholder Maize Productivity in Malawi: Toward an African Green Revolution

Glenn Denning, Patrick Kabambe, Pedro Sanchez, Alia Malik, Rafael Flor, Rebbie Harawa, Phelire Nkhoma, Colleen Zamba, Clement Banda, Chrispin Magombo, Michael Keating, Justine Wangila, Jeffrey Sachs

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000023

From Creation to Consolidation: A Novel Framework for Memory Processing

Edwin M Robertson

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000019

Perspectives

The Publisher's Pushback against NIH's Public Access and Scholarly Publishing Sustainability

John Willinsky

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000030

Integrated Ecosystem Assessments: Developing the Scientific Basis for Ecosystem-Based Management of the Ocean

Phillip S Levin, Michael J Fogarty, Steven A Murawski, David Fluharty

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000014

Primers

A New Look at Some Old Animals

Neil W Blackstone

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000007

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Biological Systems from an Engineer's Point of View

Gregory T Reeves, Scott E Fraser

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000021

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Research Articles

Concatenated Analysis Sheds Light on Early Metazoan Evolution and Fuels a Modern “Urmetazoon” Hypothesis

Bernd Schierwater, Michael Eitel, Wolfgang Jakob, Hans-Jürgen Osigus, Heike Hadrys, Stephen L Dellaporta, Sergios-Orestis Kolokotronis, Rob DeSalle

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000020

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Hotspots of Biased Nucleotide Substitutions in Human Genes

Jonas Berglund, Katherine S Pollard, Matthew T Webster

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000026

When Learning and Remembering Compete: A Functional MRI Study

Willem Huijbers, Cyriel M Pennartz, Roberto Cabeza, Sander M Daselaar

PLOS Biology: published January 13, 2009 | https://doi.org/10.1371/journal.pbio.1000011

A Point Mutation in the Hair Cell Nicotinic Cholinergic Receptor Prolongs Cochlear Inhibition and Enhances Noise Protection

Julian Taranda, Stéphane F Maison, Jimena A Ballestero, Eleonora Katz, Jessica Savino, Douglas E Vetter, Jim Boulter, M. Charles Liberman, Paul A Fuchs, A. Belén Elgoyhen

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000018

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Cell Lineages and the Logic of Proliferative Control

Arthur D Lander, Kimberly K Gokoffski, Frederic Y. M Wan, Qing Nie, Anne L Calof

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000015

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Collective Cell Migration Drives Morphogenesis of the Kidney Nephron

Aleksandr Vasilyev, Yan Liu, Sudha Mudumana, Steve Mangos, Pui-Ying Lam, Arindam Majumdar, Jinhua Zhao, Kar-Lai Poon, Igor Kondrychyn, Vladimir Korzh, Iain A Drummond

PLOS Biology: published January 6, 2009 | https://doi.org/10.1371/journal.pbio.1000009

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

Donatella Valdembri, Patrick T Caswell, Kurt I Anderson, Juliane P Schwarz, Ireen König, Elena Astanina, Francesca Caccavari, Jim C Norman, Martin J Humphries, Federico Bussolino, Guido Serini

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000025

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A Novel Function for Fragile X Mental Retardation Protein in Translational Activation

Elias G Bechara, Marie Cecile Didiot, Mireille Melko, Laetitia Davidovic, Mounia Bensaid, Patrick Martin, Marie Castets, Philippe Pognonec, Edouard W Khandjian, Hervé Moine, Barbara Bardoni

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000016

Functional Anatomy of Polycomb and Trithorax Chromatin Landscapes in Drosophila Embryos

Bernd Schuettengruber, Mythily Ganapathi, Benjamin Leblanc, Manuela Portoso, Rami Jaschek, Bas Tolhuis, Maarten van Lohuizen, Amos Tanay, Giacomo Cavalli

PLOS Biology: published January 13, 2009 | https://doi.org/10.1371/journal.pbio.1000013

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes

Michal Skružný, Claudia Schneider, Attila Rácz, Julan Weng, David Tollervey, Ed Hurt

PLOS Biology: published January 6, 2009 | https://doi.org/10.1371/journal.pbio.1000008

The Influence of Catalysis on Mad2 Activation Dynamics

Marco Simonetta, Romilde Manzoni, Roberto Mosca, Marina Mapelli, Lucia Massimiliano, Martin Vink, Bela Novak, Andrea Musacchio, Andrea Ciliberto

PLOS Biology: published January 13, 2009 | https://doi.org/10.1371/journal.pbio.1000010

Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition

Véronique Calleja, Michel Laguerre, Peter J Parker, Banafshé Larijani

PLOS Biology: published January 20, 2009 | https://doi.org/10.1371/journal.pbio.1000017

Correction

Correction: Caldendrin–Jacob: A Protein Liaison That Couples NMDA Receptor Signalling to the Nucleus

Daniela C Dieterich, Anna Karpova, Marina Mikhaylova, Irina Zdobnova, Imbritt König, Marco Landwehr, Martin Kreutz, Karl-Heinz Smalla, Karin Richter, Peter Landgraf, Carsten Reissner, Tobias M Boeckers, Werner Zuschratter, Christina Spilker, Constanze I Seidenbecher, Craig C Garner, Eckart D Gundelfinger, Michael R Kreutz

PLOS Biology: published January 27, 2009 | https://doi.org/10.1371/journal.pbio.1000022

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