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Table of Contents

June 2008

Cover

A fluorescence micrograph of cells expressing a reconstructed ancestral CDC14Bretro protein variant from the last common great ape.
Issue Image

Subcellular localization of a reconstructed ancestral CDC14Bretro protein from the last common great ape ancestor. A fluorescence micrograph of COS7 cells expressing a resurrected CDC14Bretro protein variant from the last common great ape ancestor (tagged with green fluorescent protein), co-localizing (yellow) with microtubules (stained in red with an anti-beta tubulin antibody) is shown. Cells are also co-stained with DAPI (blue) to visualize cell nuclei (see Rosso et al.).

Image Credit: Image generated by Lia Rosso

Synopses

A Roadmap for Migrating Neurons

Caitlin Sedwick

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060153

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The Ticket to Transport

Mary Hoff

PLOS Biology: published June 3, 2008 | https://doi.org/10.1371/journal.pbio.0060144

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The Fourth Dimension of Biochemical Pathways

Richard Robinson

PLOS Biology: published June 17, 2008 | https://doi.org/10.1371/journal.pbio.0060151

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Essay

Beyond Competition: Incorporating Positive Interactions between Species to Predict Ecosystem Invasibility

Fabio Bulleri, John F Bruno, Lisandro Benedetti-Cecchi

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060162

Primers

On the Emergence and Awareness of Auditory Objects

Shihab Shamma

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060155

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  2. Neural Correlates of Auditory Perceptual Awareness under Informational Masking

Micromanagement of Lymphomas

Enrico Arpaia, Tak W Mak

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060156

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Unravelling the Bcl-2 Apoptosis Code with a Simple Model System

Gorka Basañez, J. Marie Hardwick

PLOS Biology: published June 17, 2008 | https://doi.org/10.1371/journal.pbio.0060154

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Community Page

Gene Banks Pay Big Dividends to Agriculture, the Environment, and Human Welfare

R. C Johnson

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060148

Research Articles

Neural Correlates of Auditory Perceptual Awareness under Informational Masking

Alexander Gutschalk, Christophe Micheyl, Andrew J Oxenham

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060138

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Two-Dimensional Patterning by a Trapping/Depletion Mechanism: The Role of TTG1 and GL3 in Arabidopsis Trichome Formation

Daniel Bouyer, Florian Geier, Friedrich Kragler, Arp Schnittger, Martina Pesch, Katja Wester, Rachappa Balkunde, Jens Timmer, Christian Fleck, Martin Hülskamp

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060141

Hox Paralog Group 2 Genes Control the Migration of Mouse Pontine Neurons through Slit-Robo Signaling

Marc J Geisen, Thomas Di Meglio, Massimo Pasqualetti, Sebastien Ducret, Jean-François Brunet, Alain Chedotal, Filippo M Rijli

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060142

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Selective Ligand Recognition by a Diversity-Generating Retroelement Variable Protein

Jason L Miller, Johanne Le Coq, Asher Hodes, Roman Barbalat, Jeff F Miller, Partho Ghosh

PLOS Biology: published June 3, 2008 | https://doi.org/10.1371/journal.pbio.0060131

The B Cell Antigen Receptor and Overexpression of MYC Can Cooperate in the Genesis of B Cell Lymphomas

Yosef Refaeli, Ryan M Young, Brian C Turner, Jennifer Duda, Kenneth A Field, J. Michael Bishop

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060152

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Immunoglobulin Heavy Chain Exclusion in the Shark

Karolina Malecek, Victor Lee, Wendy Feng, Jing Li Huang, Martin F Flajnik, Yuko Ohta, Ellen Hsu

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060157

Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase

Louisa McRobert, Cathy J Taylor, Wensheng Deng, Quinton L Fivelman, Ross M Cummings, Spencer D Polley, Oliver Billker, David A Baker

PLOS Biology: published June 3, 2008 | https://doi.org/10.1371/journal.pbio.0060139

Modular Organization and Combinatorial Energetics of Proline–Tyrosine Nuclear Localization Signals

Katherine E Süel, Hongmei Gu, Yuh Min Chook

PLOS Biology: published June 3, 2008 | https://doi.org/10.1371/journal.pbio.0060137

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Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax

Lieven P Billen, Candis L Kokoski, Jonathan F Lovell, Brian Leber, David W Andrews

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060147

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Birth and Rapid Subcellular Adaptation of a Hominoid-Specific CDC14 Protein

Lia Rosso, Ana Claudia Marques, Manuela Weier, Nelle Lambert, Marie-Alexandra Lambot, Pierre Vanderhaeghen, Henrik Kaessmann

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060140

The Evolution of the DLK1-DIO3 Imprinted Domain in Mammals

Carol A Edwards, Andrew J Mungall, Lucy Matthews, Edward Ryder, Dionne J Gray, Andrew J Pask, Geoffrey Shaw, Jennifer A.M Graves, Jane Rogers, the SAVOIR consortium, Ian Dunham, Marilyn B Renfree, Anne C Ferguson-Smith

PLOS Biology: published June 3, 2008 | https://doi.org/10.1371/journal.pbio.0060135

Group II Intron Protein Localization and Insertion Sites Are Affected by Polyphosphate

Junhua Zhao, Wei Niu, Jun Yao, Sabine Mohr, Edward M Marcotte, Alan M Lambowitz

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060150

Structural Basis for the Regulation Mechanism of the Tyrosine Kinase CapB from Staphylococcus aureus

Vanesa Olivares-Illana, Philippe Meyer, Emmanuelle Bechet, Virginie Gueguen-Chaignon, Didier Soulat, Sylvie Lazereg-Riquier, Ivan Mijakovic, Josef Deutscher, Alain J Cozzone, Olivier Laprévote, Solange Morera, Christophe Grangeasse, Sylvie Nessler

PLOS Biology: published June 10, 2008 | https://doi.org/10.1371/journal.pbio.0060143

Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPD

Stefanie C Wolski, Jochen Kuper, Petra Hänzelmann, James J Truglio, Deborah L Croteau, Bennett Van Houten, Caroline Kisker

PLOS Biology: published June 24, 2008 | https://doi.org/10.1371/journal.pbio.0060149

Dynamics and Design Principles of a Basic Regulatory Architecture Controlling Metabolic Pathways

Chen-Shan Chin, Victor Chubukov, Emmitt R Jolly, Joe DeRisi, Hao Li

PLOS Biology: published June 17, 2008 | https://doi.org/10.1371/journal.pbio.0060146

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