Notch3 is an asymmetric gene and a modifier of heart looping defects in Nodal mouse mutants

• Tobias Holm Bønnelykke,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Supervision, Visualization, Writing – review & editing

  Affiliations Université Paris Cité, Imagine—Institut Pasteur Unit of Heart Morphogenesis , INSERM UMR1163, Paris, France, Sorbonne Université, Collège Doctoral, Paris, France

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• Marie-Amandine Chabry,

  Roles Formal analysis, Investigation, Visualization, Writing – review & editing

  Affiliation Université Paris Cité, Imagine—Institut Pasteur Unit of Heart Morphogenesis , INSERM UMR1163, Paris, France

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• Emeline Perthame,

  Roles Formal analysis, Methodology, Software, Visualization, Writing – review & editing

  Affiliations Université Paris Cité, Imagine—Institut Pasteur Unit of Heart Morphogenesis , INSERM UMR1163, Paris, France, Institut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics Hub, Paris, France

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• Gregor Dombrowsky,

  Roles Data curation, Formal analysis, Visualization, Writing – review & editing

  Affiliation Department for Medical Genetics, University of Oldenburg, Oldenburg, Germany

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• Felix Berger,

  Roles Resources, Writing – review & editing

  Affiliation Department of Congenital Heart Disease, Pediatric Cardiology Deutsches Herzzentrum der Charité, Charité Universitätsmedizin Berlin, Berlin, Germany

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• Sven Dittrich,

  Roles Resources, Writing – review & editing

  Affiliation Department of Pediatric Cardiology, University Hospital Erlangen, Friedrich-Alexander-University of Erlangen-Nürnberg, Erlangen, Germany

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• Marc-Phillip Hitz,

  Roles Writing – review & editing, Data curation, Formal analysis

  Affiliations Department for Medical Genetics, University of Oldenburg, Oldenburg, Germany, German Center for Cardiovascular Research (DZHK), Kiel, Germany

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• Audrey Desgrange ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – review & editing

  ¶‡ These authors are co-senior authors on this work.

  Affiliation Université Paris Cité, Imagine—Institut Pasteur Unit of Heart Morphogenesis , INSERM UMR1163, Paris, France

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• Sigolène M. Meilhac

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: sigolene.meilhac@institutimagine.org

  ¶‡ These authors are co-senior authors on this work.

  Affiliation Université Paris Cité, Imagine—Institut Pasteur Unit of Heart Morphogenesis , INSERM UMR1163, Paris, France

  https://orcid.org/0000-0003-4080-2617

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