TSC1/mTOR-controlled metabolic–epigenetic cross talk underpins DC control of CD8⁺ T-cell homeostasis

• Lei Shi ,

  Roles Data curation, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors are co-first authors on this work.

  Affiliations School of Life Sciences, Lanzhou University, Lanzhou, Gansu, China, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Xia Chen ,

  Roles Data curation, Investigation, Methodology, Project administration, Resources, Software, Validation, Writing – original draft, Writing – review & editing

  ¶‡ These authors are co-first authors on this work.

  Affiliations School of Life Sciences, Lanzhou University, Lanzhou, Gansu, China, CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Aiping Zang,

  Roles Investigation

  Affiliation CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Tiantian Li,

  Roles Investigation

  Affiliation CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Yanxiang Hu,

  Roles Investigation

  Affiliation Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong, China

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• Shixin Ma,

  Roles Investigation, Methodology

  Affiliation CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Mengdie Lü,

  Roles Investigation, Methodology

  Affiliation Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Diseases, Guangzhou, Guangdong, China

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• Huiyong Yin,

  Roles Investigation, Methodology

  Affiliation CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China

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• Haikun Wang,

  Roles Investigation, Methodology

  Affiliation CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Xiaoming Zhang,

  Roles Investigation, Methodology

  Affiliation CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

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• Bei Zhang,

  Roles Investigation

  Affiliation Department of Immunology, Medical College of Qingdao University, Qingdao, Shandong, China

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• Qibin Leng ,

  Roles Investigation, Methodology, Resources

  * E-mail: huixiao@ips.ac.cn (HX); yangjb@lzu.edu.cn (JY); qbleng@gzhmu.edu.cn (QL)

  Affiliation Affiliated Cancer Hospital and Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Diseases, Guangzhou, Guangdong, China

  http://orcid.org/0000-0002-4768-1312

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• Jinbo Yang ,

  Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Supervision

  * E-mail: huixiao@ips.ac.cn (HX); yangjb@lzu.edu.cn (JY); qbleng@gzhmu.edu.cn (QL)

  Affiliation School of Life Sciences, Lanzhou University, Lanzhou, Gansu, China

  ⨯
• Hui Xiao

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: huixiao@ips.ac.cn (HX); yangjb@lzu.edu.cn (JY); qbleng@gzhmu.edu.cn (QL)

  Affiliation CAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai; CAS Center for Excellence in Molecular Cell Science; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China

  http://orcid.org/0000-0001-5304-243X

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